Aliases for ACAA2 Gene
External Ids for ACAA2 Gene
Previous GeneCards Identifiers for ACAA2 Gene
The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACAA2 Gene
ACAA2 (Acetyl-CoA Acyltransferase 2) is a Protein Coding gene. Diseases associated with ACAA2 include progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 2 and mitochondrial dna depletion syndrome 12. Among its related pathways are Fatty acid metabolism and Fatty Acyl-CoA Biosynthesis. GO annotations related to this gene include poly(A) RNA binding and acetyl-CoA C-acyltransferase activity. An important paralog of this gene is ACAT2.
UniProtKB/Swiss-Prot for ACAA2 Gene
Abolishes BNIP3-mediated apoptosis and mitochondrial damage.