Aliases for ACAA1 Gene
Aliases for ACAA1 Gene
External Ids for ACAA1 Gene
- HGNC: 82
- Entrez Gene: 30
- Ensembl: ENSG00000060971
- OMIM: 604054
- UniProtKB: P09110
Previous GeneCards Identifiers for ACAA1 Gene
- GC03M037452
- GC03M037977
- GC03M038124
- GC03M038139
- GC03M038164
Summaries for ACAA1 Gene
-
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACAA1 Gene
ACAA1 (Acetyl-CoA Acyltransferase 1) is a Protein Coding gene. Diseases associated with ACAA1 include Chondrodysplasia Punctata Syndrome and Alpha-Methylacetoacetic Aciduria. Among its related pathways are fatty acid beta-oxidation (peroxisome) and Innate Immune System. GO annotations related to this gene include transferase activity, transferring acyl groups other than amino-acyl groups and palmitoyl-CoA oxidase activity. An important paralog of this gene is HADHB.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACAA1 Gene
Genomics for ACAA1 Gene
Regulatory Elements for ACAA1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH03G038163 | 2 | FANTOM5 Ensembl ENCODE dbSUPER | 20.4 | -30.0 | -29957 | 8.0 | MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 | OXSR1 ACAA1 MYD88 C3orf35 GORASP1 SLC22A13 ACVR2B-AS1 VILL PLCD1 DLEC1 |
| GH03G038150 | 1.7 | FANTOM5 Ensembl ENCODE dbSUPER | 11.6 | -15.9 | -15872 | 5.0 | HDAC1 ZFP64 GATA2 FOS NFYC CEBPB USF2 ZEB2 REST ELF1 | VILL MYD88 OXSR1 ACAA1 |
| GH03G038129 | 1.4 | ENCODE dbSUPER | 10.8 | +2.7 | 2667 | 10.9 | HDGF PKNOX1 FOXA2 MLX ARNT AGO1 ZFP64 ARID4B SIN3A DMAP1 | ACAA1 OXSR1 ENSG00000201965 GC03M038125 |
| GH03G038227 | 0.8 | Ensembl ENCODE | 16.1 | -90.8 | -90789 | 1.1 | JUN BHLHE40 SCRT2 CEBPB CEBPG | ACAA1 MYD88 GC03P038253 PIR62277 LOC101928234 |
| GH03G038102 | 0.8 | FANTOM5 Ensembl | 11.8 | +34.8 | 34790 | 0.9 | IKZF1 ZNF341 KDM1A | MYD88 VILL ACAA1 SLC22A13 PLCD1 OXSR1 SLC22A14 PIR60395 GC03M038048 |
- Transcription factor binding sites by QIAGEN in the ACAA1 gene promoter:
Regulatory Element Products
Genomic Location for ACAA1 Gene
- Chromosome:
- 3
- Start:
- 38,103,129 bp from pter
- End:
- 38,137,242 bp from pter
- Size:
- 34,114 bases
- Orientation:
- Minus strand
Genomic View for ACAA1 Gene
- Cytogenetic band:
-
- 3p22.2 by Ensembl
- 3p22.2 by Entrez Gene
- 3p22.2 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ACAA1 Gene
Proteins for ACAA1 Gene
-
Protein details for ACAA1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P09110-THIK_HUMAN
- Recommended name:
- 3-ketoacyl-CoA thiolase, peroxisomal
- Protein Accession:
- P09110
- G5E935
- Q96CA6
Protein attributes for ACAA1 Gene
- Size:
- 424 amino acids
- Molecular mass:
- 44292 Da
- Quaternary structure:
-
- Homodimer.
Protein Expression for ACAA1 Gene
Selected DME Specific Peptides for ACAA1 Gene
- P09110:
-
- TLLNELKRRG
- GSTTAGN
- GMGAAAVFE
- EKVNPLGGA
- PAFKKDG
- GLPILGV
- MARIAQFLS
- FALASQQKAA
- PMGITSENVA
- RGGFKDT
- DVVVVHGRRT
- NRQCSSGL
- RLQVVLGHL
- SMCIGTGMGAA
- FEINEAFA
- CLIPMGIT
Post-translational modifications for ACAA1 Gene
Other Protein References for ACAA1 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ACAA1
- Novus Biologicals Antibodies for ACAA1
-
Cloud-Clone Corp. Antibodies for ACAA1
- Invitrogen Antibodies for ACAA1
- antibodies-online Antibodies for ACAA1: See all 62
- GeneTex ACAA1 antibody for ACAA1
-
Santa Cruz Biotechnology (SCBT) Antibodies for ACAA1
Protein Products
-
OriGene Purified Proteins for ACAA1
- Search Origene for MassSpec and Protein Over-expression Lysates for ACAA1
- Origene Custom Protein Services for ACAA1
- Sino Biological Recombinant Proteins for ACAA1
- Sino Biological Cell Lysates for ACAA1
- ProSpec Recombinant Proteins for ACAA1
-
Cloud-Clone Corp. Proteins for ACAA1
- antibodies-online Proteins for ACAA1: See all 14
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ACAA1
Assay Products
Domains & Families for ACAA1 Gene
Protein Domains for ACAA1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ACAA1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P09110- Family:
-
- Belongs to the thiolase family.
No data available for Gene Families for ACAA1 Gene
Function for ACAA1 Gene
Molecular function for ACAA1 Gene
- GENATLAS Biochemistry:
- acetyl-CoA acyltransferase,(peroxisomal matrix 3-oxoacyl-CoA thiolase),medium or long chain,catalyzing the fourth step of fatty acid beta-oxidation,expressed
- UniProtKB/Swiss-Prot CatalyticActivity:
- Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
- UniProtKB/Swiss-Prot Induction:
- Peroxisomal thiolase is markedly induced (at the level of transcription) by various hypolipidemic compounds in parallel with the other two enzymes of the peroxisomal beta-oxidation system.
Enzyme Numbers (IUBMB) for ACAA1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003824 | catalytic activity | IEA | -- |
| GO:0003988 | acetyl-CoA C-acyltransferase activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 18281296 |
| GO:0008775 | acetate CoA-transferase activity | EXP | 11734571 |
| GO:0016401 | palmitoyl-CoA oxidase activity | IMP | 2882519 |
Phenotypes for ACAA1 Gene
- MGI mutant phenotypes for ACAA1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ACAA1:
-
- Increased vaccinia virus (VACV) infection
- Decreased shRNA abundance (Z-score < -2)
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Wnt reporter downregulated
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Downregulation of Wnt pathway after Wnt3A stimulation
Animal Models for ACAA1 Gene
- MGI Knock Outs for ACAA1:
-
- Acaa1a tm1a(KOMP)Wtsi
Animal Model Products
-
Taconic Biosciences Mouse Models for ACAA1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACAA1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ACAA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAA1 gene
- Search ViGene Biosciences for ACAA1
CRISPR Products
-
OriGene CRISPR knockouts for ACAA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACAA1
- GenScript: Design CRISPR guide RNA sequences for ACAA1
miRNA for ACAA1 Gene
- miRTarBase miRNAs that target ACAA1
miRNA Products
- Search ViGene Biosciences for ACAA1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ACAA1
- Browse OriGene Inhibitory RNA Products For ACAA1
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAA1 gene
Clone Products
- Sino Biological Human cDNA Clone for ACAA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ACAA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACAA1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ACAA1
-
ViGene Biosciences adenoviral particle packaged cDNA for ACAA1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ACAA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAA1 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ACAA1 Gene
Localization for ACAA1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ACAA1 Gene
- Peroxisome.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005777 | peroxisome | IEA,IDA | 1347505 |
| GO:0005782 | peroxisomal matrix | TAS | -- |
| GO:0016020 | membrane | IDA | 19946888 |
| GO:0035580 | specific granule lumen | TAS | -- |
Pathways & Interactions for ACAA1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.37
|
|
| 2 | Innate Immune System |
.61
|
|
| 3 | Fatty acid metabolism | ||
| 4 | alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | ||
| 5 | Peroxisomal lipid metabolism | ||
Pathways by source for ACAA1 Gene
4 BioSystems pathways for ACAA1 Gene
8 KEGG pathways for ACAA1 Gene
UniProtKB/Swiss-Prot P09110-THIK_HUMAN
- Pathway: Lipid metabolism; fatty acid metabolism.
Interacting Proteins for ACAA1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000038 | very long-chain fatty acid metabolic process | IMP | 2318981 |
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006631 | fatty acid metabolic process | IEA | -- |
| GO:0006635 | fatty acid beta-oxidation | IMP | 2365812 |
| GO:0008152 | metabolic process | IEA | -- |
No data available for SIGNOR curated interactions for ACAA1 Gene
Drugs & Compounds for ACAA1 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| (+)-7-Isojasmonic acid CoA |
|
|
|
|||
| (2E)-Decenoyl-CoA |
|
10018-95-8 |
|
|||
| (2E)-Dodecenoyl-CoA |
|
1066-12-2 |
|
|||
| (2E)-Hexadecenoyl-CoA |
|
4460-95-1 |
|
|||
| (2E)-Octenoyl-CoA |
|
10018-94-7 |
|
Transcripts for ACAA1 Gene
mRNA/cDNA for ACAA1 Gene
- (5) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (488) Selected AceView cDNA sequences:
- (20) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ACAA1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ACAA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACAA1
- GenScript: Design CRISPR guide RNA sequences for ACAA1
miRNA Products
- Search ViGene Biosciences for ACAA1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ACAA1
- Browse OriGene Inhibitory RNA Products For ACAA1
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAA1 gene
Clone Products
- Sino Biological Human cDNA Clone for ACAA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ACAA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACAA1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: |
| ExUns: | 14a | · | 14b | · | 14c | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | · | 17d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: | |||||||||||||||||||
| SP4: | |||||||||||||||||||
| SP5: | |||||||||||||||||||
| SP6: | |||||||||||||||||||
| SP7: | |||||||||||||||||||
| SP8: | |||||||||||||||||||
| SP9: | - | - | - | ||||||||||||||||
| SP10: | |||||||||||||||||||
| SP11: | - | - | - | ||||||||||||||||
| SP12: | - | - | - | ||||||||||||||||
| SP13: | |||||||||||||||||||
| SP14: | |||||||||||||||||||
| SP15: | - | - | - | ||||||||||||||||
| SP16: | |||||||||||||||||||
| SP17: | |||||||||||||||||||
| SP18: | |||||||||||||||||||
| SP19: |
Expression for ACAA1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Neural Tube (Nervous System)
- Kidney (Urinary System)
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
- Eye (Sensory Organs)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Spleen (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for ACAA1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ACAA1 Gene
NURSA nuclear receptor signaling pathways regulating expression of ACAA1 Gene:
ACAA1SOURCE GeneReport for Unigene cluster for ACAA1 Gene:
Hs.643487Evidence on tissue expression from TISSUES for ACAA1 Gene
- Liver(4.8)
- Nervous system(4.4)
- Pancreas(4.3)
- Intestine(2.9)
- Lung(2.9)
- Blood(2.3)
- Heart(2.2)
- Kidney(2.1)
- Muscle(2)
Primer Products
-
OriGene qPCR primer pairs for ACAA1
-
OriGene qPCR primer pairs and template standards for ACAA1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ACAA1 Gene
Orthologs for ACAA1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ACAA1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ACAA1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ACAA1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Acaa1b 35 |
|
OneToMany | |
| Acaa1a 34 16 35 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Acaa1b 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ACAA1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ACAA1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ACAA1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ACAA1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | acaa1 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | acaa1-prov 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | acaa1 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | POT1 35 37 |
|
OneToOne | |
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.5310 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os10g0457600 34 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.28367 34 |
|
- Species where no ortholog for ACAA1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- worm (Caenorhabditis elegans)
Paralogs for ACAA1 Gene
(4) SIMAP similar genes for ACAA1 Gene using alignment to 8 proteins:
Variants for ACAA1 Gene
| SNP ID | Clin | Chr 03 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs137853065 | Pathogenic | 38,138,978(+) | GCTGC(C/T)TACCA | upstream-variant-2KB, reference, missense | |
| rs878852993 | Pathogenic | 38,138,853(+) | CTGGC(-/GGA)GGAGA | upstream-variant-2KB, cds-indel | |
| rs201871349 | untested | 38,138,780(+) | CAACA(C/T)GCGAG | upstream-variant-2KB, reference, missense | |
| rs587778543 | untested | 38,138,821(+) | TGCGG(A/T)CACAG | upstream-variant-2KB, reference, missense | |
| rs587778544 | untested | 38,138,692(+) | CAGGA(C/G)CGCCC | upstream-variant-2KB, reference, missense |
Relevant External Links for ACAA1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACAA1 Gene
Disorders for ACAA1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chondrodysplasia punctata syndrome |
|
|
| alpha-methylacetoacetic aciduria |
|
|
| alpha-methylacyl-coa racemase deficiency |
|
|
| cardiomyopathy, hypertrophic, 20 |
|
|
Genatlas disease for ACAA1 Gene
Relevant External Links for ACAA1
No data available for UniProtKB/Swiss-Prot for ACAA1 Gene
Publications for ACAA1 Gene
- Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient. (PMID: 1679347) Bout A. … Benne R. (Biochim. Biophys. Acta 1991) 3 4 22 64
- Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P. … Inskip P.D. (Cancer Epidemiol. Biomarkers Prev. 2010) 3 46 64
- Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S. … Kang D. (Hum. Immunol. 2010) 3 46 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 46 64
Products for ACAA1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ACAA1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ACAA1
- Search Origene for MassSpec and Protein Over-expression Lysates for ACAA1
- Origene Custom Protein Services for ACAA1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ACAA1
- Browse OriGene Inhibitory RNA Products For ACAA1
- OriGene qPCR primer pairs and template standards for ACAA1
- OriGene qPCR primer pairs for ACAA1
- OriGene CRISPR knockouts for ACAA1
- OriGene ORF clones in human for ACAA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ACAA1
- GenScript: Next-day shipping cDNA ORF clone for ACAA1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ACAA1
- GenScript Custom Assay Services for ACAA1
- GenScript Custom overexpressing Cell Line Services for ACAA1
- GenScript: Design CRISPR guide RNA sequences for ACAA1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ACAA1
- Sino Biological Human cDNA Clone for ACAA1
- Sino Biological Recombinant Proteins for ACAA1
- Sino Biological Cell Lysates for ACAA1
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ACAA1
- Novus Biologicals proteins and lysates for ACAA1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for ACAA1
- Cloud-Clone Corp. Antibodies for ACAA1
- Cloud-Clone Corp. Proteins for ACAA1
- Browse Assay Kits at Cloud-Clone Corp.
- Taconic Biosciences Mouse Models for ACAA1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for ACAA1: See all 62
- Search antibodies-online for kits
- antibodies-online Proteins for ACAA1: See all 14
- Search antibodies-online for peptides
- GeneTex ACAA1 antibody for ACAA1
- Search GeneTex for Proteins for ACAA1
- ViGene Biosciences adenoviral particle packaged cDNA for ACAA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ACAA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ACAA1 gene
- Search ViGene Biosciences for ACAA1
- Santa Cruz Biotechnology (SCBT) Antibodies for ACAA1
- Search Santa Cruz Biotechnology (SCBT) for ACAA1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ACAA1
- Horizon Cell Lines for ACAA1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACAA1
- VectorBuilder custom plasmid, inducible vectors for ACAA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACAA1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ACAA1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




