Aliases for ABT1 Gene
External Ids for ABT1 Gene
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABT1 Gene
ABT1 (Activator Of Basal Transcription 1) is a Protein Coding gene. Diseases associated with ABT1 include essential thrombocythemia and roberts syndrome. GO annotations related to this gene include RNA binding and transcription coactivator activity.
UniProtKB/Swiss-Prot for ABT1 Gene
Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity).