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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ABT1 Gene

protein-coding GIFtS: 49
GCID: GC06P026597

Activator Of Basal Transcription 1

Microbiology & Infectious Diseases Congress

17 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Activator Of Basal Transcription 1¹ ²
Basal Transcriptional Activator² ³
hABT1² ³
TATA-Binding Protein-Binding Protein²

External Ids:	HGNC: 17369¹	Entrez Gene: 29777²	Ensembl: ENSG00000146109⁷	UniProtKB: Q9ULW3³

Export aliases for ABT1 gene to outside databases

Previous GC identifers: GC06P026654 GC06P026705 GC06P026540

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABT1 Gene:

Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core

region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal

transcription from class II promoters by interaction with TBP and the class II promoter DNA. (provided by RefSeq, Jul

2008)

GeneCards Summary for ABT1 Gene:

ABT1 (activator of basal transcription 1) is a protein-coding gene. Diseases associated with ABT1 include neuronal intranuclear inclusion disease, and roberts syndrome. GO annotations related to this gene include transcription coactivator activity and RNA binding.

UniProtKB/Swiss-Prot: ABT1_HUMAN, Q9ULW3

Function: Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as

a regulator of basal transcription for class II genes (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.2 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ABT1 gene promoter:
TBP FOXD1 LCR-F1 Evi-1 GATA-2 NRF-2 FOXO1a ATF6 FOXO1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ABT1 promoter sequence

Search SABiosciences Chromatin IP Primers for ABT1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABT1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.2 Ensembl cytogenetic band: 6p22.2 HGNC cytogenetic band: 6p21.31

ABT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABT1 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06P026597: view genomic region (about GC identifiers)

Start:	26,597,171 bp from pter	End:	26,600,278 bp from pter
Size:	3,108 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ABT1_HUMAN, Q9ULW3 (See protein sequence)

Recommended Name: Activator of basal transcription 1

Size: 272 amino acids; 31079 Da

Subunit: Interacts with ESF1/ABTAP (By similarity). Interacts with IGHMBP2

Subcellular location: Nucleus (By similarity). Nucleus, nucleolus (By similarity)

Explore the universe of human proteins at neXtProt for ABT1: NX_Q9ULW3

Explore proteomics data for ABT1 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q9ULW3

ABT1 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_037507.1

ENSEMBL proteins:

ENSP00000274849

Human Recombinant Protein Products for ABT1:

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	Cloud-Clone Corp. Proteins for ABT1

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	TAS	10648625
GO:0005667	transcription factor complex	IEA	--
GO:0005730	nucleolus	IEA	--

ABT1 for ontologies About GeneDecksing

ABT1 Antibody Products:

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	LSBio Antibodies in human, mouse, rat for ABT1

Assay Products for ABT1:

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	Cloud-Clone Corp. ELISAs for ABT1 Cloud-Clone Corp. CLIAs for ABT1

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

1 InterPro protein domain:

IPR012677 Nucleotide-bd_a/b_plait

Graphical View of Domain Structure for InterPro Entry Q9ULW3

ProtoNet protein and cluster: Q9ULW3

UniProtKB/Swiss-Prot: ABT1_HUMAN, Q9ULW3

Similarity: Belongs to the ESF2/ABP1 family

Similarity: Contains 1 RRM (RNA recognition motif) domain

ABT1 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ABT1_HUMAN, Q9ULW3

Function: Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as

a regulator of basal transcription for class II genes (By similarity)

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003677	DNA binding	IEA	--
GO:0003713	transcription coactivator activity	TAS	10648625
GO:0003723	RNA binding	IEA	--
GO:0005515	protein binding	IPI	19299493

ABT1 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ABT1:

Decreased number of cells in m

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for ABT1

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ABT1

miRNA Products:
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		5 QIAGEN miScript miRNA Assays for microRNAs that regulate ABT1:
		hsa-miR-1290 hsa-miR-183* hsa-miR-4251 hsa-miR-3116 hsa-miR-3157-5p
		SwitchGear 3'UTR luciferase reporter plasmid: ABT1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: ABT1 (NM_013375)
		Sino Biological Human cDNA Clone for ABT1
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABT1

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABT1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ABT1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/31 Interacting proteins for ABT1 (Q9ULW3³ ENSP00000274849⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 31)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TBP	P20226³, ENSP00000230354⁴	I2D: score=1 STRING: ENSP00000230354
NCAM2	O15394³	I2D: score=1
PRNP	P04156³	I2D: score=1
PWP2	ENSP00000291576⁴	STRING: ENSP00000291576
NOL10	ENSP00000371101⁴	STRING: ENSP00000371101

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006357	regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006366	transcription from RNA polymerase II promoter	IEA	--
GO:0021522	spinal cord motor neuron differentiation	IEA	--

ABT1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

ABT1 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ABT1

8 Novoseek inferred chemical compound relationships for ABT1 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
tbps	79.9	1	8253078 (1)
glutamine	27.6	4	15977647 (1), 18043721 (1)
rrna	13.6	1	9843972 (1)
s-adenosylmethionine	4.88	1	9878798 (1)
zinc	4.56	1	10819460 (1)
tyrosine	0	1	8094701 (1)
leucine	0	1	15659240 (1)
alanine	0	1	8577725 (1)

Search CenterWatch for drugs/clinical trials and news about ABT1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ABT1 gene:

NM_013375.3

Unigene Cluster for ABT1:

Activator of basal transcription 1

Hs.254406 [show with all ESTs]

Unigene Representative Sequence: NM_013375

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000274849(uc003nii.3)

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA Products:
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		5 QIAGEN miScript miRNA Assays for microRNAs that regulate ABT1:
		hsa-miR-1290 hsa-miR-183* hsa-miR-4251 hsa-miR-3116 hsa-miR-3157-5p
		SwitchGear 3'UTR luciferase reporter plasmid: ABT1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for ABT1
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		Sirion Biotech Custom design and validation of potent shRNA sequences against ABT1

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		GenScript: all cDNA clones in your preferred vector: ABT1 (NM_013375)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABT1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABT1

Primer Products:		OriGene qPCR primer pairs and template standards for ABT1 OriGene qSTAR qPCR primer pairs in human, mouse for ABT1
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ABT1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABT1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABT1

Additional mRNA sequence:

AB027258.1 BC048812.1 BC066313.1

10 DOTS entries:

DT.415322 DT.100806016 DT.40228669 DT.100806004 DT.100806013 DT.121323758 DT.91756269 DT.95211608

DT.121323754 DT.454223

24/261 AceView cDNA sequences (see all 261):

BU632184 AA814359 BM069585 AI468953 CR596997 BM757998 CD742569 BU179168

BM747218 BU838762 AA894779 CR615011 CR590058 BM758011 AA598460 BU741142

CB111790 CA308956 BU607766 CR613442 AW273179 BM803677 BE205848 AW872764

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ABT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GAGTTTTGTG

About this image

See ABT1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABT1

SOURCE GeneReport for Unigene cluster: Hs.254406

SABiosciences Custom PCR Arrays for ABT1

Primer Products:		OriGene qPCR primer pairs and template standards for ABT1 OriGene qSTAR qPCR primer pairs in human, mouse for ABT1
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABT1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABT1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABT1 gene from 9/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Abt1^{1 , 5}	activator of basal transcription 1^{1, 5}	81.98(n)¹ 82.63(a)¹		13 (9.65 cM)⁵ 30946¹ NM_013924.3¹ NP_038952.1¹ 23421539⁵
lizard (Anolis carolinensis)	Reptilia	ABT1⁶	Uncharacterized protein	48(a)	1 ↔ 1	2(69678977-69684060)
African clawed frog (Xenopus laevis)	Amphibia	MGC52939²	similar to activator of basal transcription	73.38(n)		BC041500.1
zebrafish (Danio rerio)	Actinopterygii	abt1¹	activator of basal transcription 1	54.39(n) 52.63(a)		553568 NM_001020547.1 NP_001018383.1
fruit fly (Drosophila melanogaster)	Insecta	CG32708¹	CG32708	49.91(n) 37.84(a)		318161 NM_167174.2 NP_727306.1
worm (Caenorhabditis elegans)	Secernentea	F57B10.8¹	Protein F57B10.8	44.44(n) 34.83(a)		172368 NM_059486.2 NP_491887.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	ESF2(YNR054C)⁴ ESF2¹	Essential nucleolar protein involved in pre-18S rRNA more⁴ Esf2p¹	45.7(n)¹ 32.8(a)¹		14(724306-723356)⁴ 855790^{1, 4} NP_014452.1^{1, 4}
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G56510¹	RNA recognition motif-containing protein	46.21(n) 33.48(a)		824818 NM_001035796.1 NP_001030873.1
rice (Oryza sativa)	Liliopsida	Os07g0662600¹	hypothetical protein	44.54(n) 37.76(a)		4344189 NM_001067079.1 NP_001060544.1

ENSEMBL Gene Tree for ABT1 (if available)
TreeFam Gene Tree for ABT1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ABT1 gene

ABT1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for ABT1
PGOHUM00000245631

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs73739027^1,2	C,F	--	26595196(+)	`GTTCCA/G/TTTTTT`	1	--	us2k¹		1		WA	2
rs6915407^1,2	C,F	--	26595219(+)	`TCTGGG/ACCTGA`	1	--	us2k¹		1		WA	118
rs35058168^1,2	C	--	26595248(+)	`CGCAT-/GGTGCA`	1	--	us2k¹		0	--	--	--	--
rs6915555^1,2	C,F,A,H	--	26595267(+)	`ATTCAT/GGAATT`	1	--	us2k¹		35		NA EA NS WA CSA	3274
rs78310371^1,2	C	--	26595308(+)	`ACCCTC/GAAAAT`	1	--	us2k¹		0	--	--	--	--
rs3807028^1,2	C,F	--	26595427(+)	`TTCATA/TTTTTT`	1	--	us2k¹ trp³		5		NA WA CSA	8
rs80014529^1,2		--	26595439(+)	`TTTTTG/TTCGGT`	1	--	us2k¹		1		NA	2
rs3807029^1,2	C,F,A	--	26595446(+)	`CGGTTC/TCACGG`	1	--	us2k¹		14		NA WA CSA EA	514
rs192203131^1,2		--	26595478(+)	`ATTGAC/TACTTG`	1	--	us2k¹		0	--	--	--	--
rs182467105^1,2		--	26595643(+)	`CAACAC/TGTGTT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ABT1 (26597171 - 26600278 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for ABT1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABT1

DNA2.0 Custom Variant and Variant Library Synthesis for ABT1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ABT1 for disorders About GeneDecksing

17 diseases for ABT1: About MalaCards

neuronal intranuclear inclusion disease roberts syndrome essential thrombocythemia rabies

spinocerebellar ataxia ataxia cholera hodgkin's lymphoma

non-hodgkin lymphoma cytochrome p450 systemic lupus erythematosus t-cell leukemia

lupus erythematosus alzheimer's disease lung cancer neuronitis

leukemia

1 disease from the University of Copenhagen DISEASES database for ABT1:

Roberts syndrome

Congresses - knowledge worth sharing:
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

6 Novoseek inferred disease relationships for ABT1 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
sca17	70.1	2	15193429 (1), 18043721 (1)
spinocerebellar ataxias	48.8	1	15365789 (1)
leukemia t-cell	23.7	1	1996321 (1)
cancer	5.62	1	15337825 (1)
shock	0	2	18028214 (1), 15977647 (1)
tumors	0	1	7834749 (1)

Genetic Association Database (GAD): ABT1
Human Genome Epidemiology (HuGE) Navigator: ABT1 (1 document)

Export disorders for ABT1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ABT1 gene, integrated from 9 sources (see all 198):
(articles sorted by number of sources associating them with ABT1)

Utopia: connect your pdf to the dynamic
world of online information

A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth. (PubMed id 10648625)^{1, 2, 3} Oda T.... Muramatsu M.-A. (2000)
Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery. (PubMed id 19299493)^{1, 2} de Planell-Saguer M....Mourelatos Z. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)¹ Varjosalo M....Superti-Furga G. (2013)
Protein phosphatase 1g isoforms linked interactions in the brain. (PubMed id 23080069)¹ Esteves S.L....da Cruz e Silva E.F. (2013)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29777	HGNC: 17369	AceView: ABT1	Ensembl:ENSG00000146109	euGenes: HUgn29777
ECgene: ABT1	H-InvDB: ABT1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ABT1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ABT1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ABT1 gene:
Search GeneIP for patents involving ABT1

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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Activator Of Basal Transcription 1

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