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ABT1 Gene

protein-coding   GIFtS: 50
GCID: GC06P026597

Activator Of Basal Transcription 1

  See ABT1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Activator Of Basal Transcription 11 2
Basal Transcriptional Activator2 3
hABT12 3
TATA-Binding Protein-Binding Protein2

External Ids:    HGNC: 173691   Entrez Gene: 297772   Ensembl: ENSG000001461097   UniProtKB: Q9ULW33   

Export aliases for ABT1 gene to outside databases

Previous GC identifers: GC06P026654 GC06P026705 GC06P026540


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ABT1 Gene:
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the
core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely
activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ABT1 Gene:
ABT1 (activator of basal transcription 1) is a protein-coding gene. Diseases associated with ABT1 include spinocerebellar ataxia type 17, and roberts syndrome. GO annotations related to this gene include transcription coactivator activity and RNA binding.

UniProtKB/Swiss-Prot: ABT1_HUMAN, Q9ULW3
Function: Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can
act as a regulator of basal transcription for class II genes (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the ABT1 gene promoter:
         TBP   FOXD1   LCR-F1   Evi-1   GATA-2   NRF-2   FOXO1a   ATF6   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABT1 promoter sequence
   Search Chromatin IP Primers for ABT1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ABT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.2   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p21.31

ABT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABT1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P026597:  view genomic region     (about GC identifiers)

Start:
26,597,171 bp from pter      End:
26,600,278 bp from pter
Size:
3,108 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ABT1_HUMAN, Q9ULW3 (See protein sequence)
Recommended Name: Activator of basal transcription 1  
Size: 272 amino acids; 31079 Da
Subunit: Interacts with ESF1/ABTAP (By similarity). Interacts with IGHMBP2

Explore the universe of human proteins at neXtProt for ABT1: NX_Q9ULW3

Explore proteomics data for ABT1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys146
  • Modification sites at PhosphoSitePlus

  • See ABT1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_037507.1  
    ENSEMBL proteins: 
     ENSP00000274849  

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    antibodies-online proteins for ABT1 (4 products) 

     
    antibodies-online peptides for ABT1

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    antibodies-online antibodies for ABT1 (24 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q9ULW3

    ProtoNet protein and cluster: Q9ULW3

    UniProtKB/Swiss-Prot: ABT1_HUMAN, Q9ULW3
    Similarity: Belongs to the ESF2/ABP1 family
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    Find genes that share domains with ABT1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABT1_HUMAN, Q9ULW3
    Function: Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can
    act as a regulator of basal transcription for class II genes (By similarity)

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003677DNA binding IEA--
    GO:0003713transcription coactivator activity TAS10648625
    GO:0003723RNA binding ----
    GO:0005515protein binding IPI19299493
         
    Find genes that share ontologies with ABT1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ABT1:
     Decreased number of cells in m 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ABT1

    miRNA
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    miRTarBase miRNAs that target ABT1:
    hsa-mir-98-5p (MIRT027859), hsa-mir-196a-5p (MIRT026032), hsa-mir-124-3p (MIRT023111), hsa-let-7d-5p (MIRT032165), hsa-mir-328-3p (MIRT043755), hsa-mir-193b-3p (MIRT041584), hsa-mir-615-3p (MIRT039696), hsa-mir-186-5p (MIRT044910)

    Block miRNA regulation of human, mouse, rat ABT1 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ABT1:
    hsa-miR-1290 hsa-miR-183* hsa-miR-4251 hsa-miR-3116 hsa-miR-3157-5p
    SwitchGear 3'UTR luciferase reporter plasmidABT1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABT1_HUMAN, Q9ULW3: Nucleus (By similarity). Nucleus, nucleolus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS10648625
    GO:0005667transcription factor complex IEA--
    GO:0005730nucleolus IEA--

    Find genes that share ontologies with ABT1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ABT1
    Interactions:

        GeneGlobe Interaction Network for ABT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ABT1 (Q9ULW33 ENSP000002748494) via UniProtKB, MINT, STRING, and/or I2D (see all 81)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TBPP202263, ENSP000002303544I2D: score=1 STRING: ENSP00000230354
    NCAM2O153943I2D: score=1 
    PRNPP041563I2D: score=1 
    NOL10ENSP000003711014STRING: ENSP00000371101
    AATFENSP000002254024STRING: ENSP00000225402
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006357regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006366transcription from RNA polymerase II promoter IEA--
    GO:0021522spinal cord motor neuron differentiation IEA--

    Find genes that share ontologies with ABT1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ABT1

    8 Novoseek inferred chemical compound relationships for ABT1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tbps 79.9 1 8253078 (1)
    glutamine 27.6 4 15977647 (1), 18043721 (1)
    rrna 13.6 1 9843972 (1)
    s-adenosylmethionine 4.88 1 9878798 (1)
    zinc 4.56 1 10819460 (1)
    tyrosine 0 1 8094701 (1)
    leucine 0 1 15659240 (1)
    alanine 0 1 8577725 (1)



    Find genes that share compounds with ABT1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ABT1 gene: 
    NM_013375.3  

    Unigene Cluster for ABT1:

    Activator of basal transcription 1
    Hs.254406  [show with all ESTs]
    Unigene Representative Sequence: NM_013375
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000274849(uc003nii.3)
    miRNA
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    hsa-miR-1290 hsa-miR-183* hsa-miR-4251 hsa-miR-3116 hsa-miR-3157-5p
    SwitchGear 3'UTR luciferase reporter plasmidABT1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ABT1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABT1
    Primer
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    OriGene qPCR primer pairs and template standards for ABT1
    OriGene qSTAR qPCR primer pairs in human, mouse for ABT1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ABT1
      QuantiTect SYBR Green Assays in human, mouse, rat ABT1
      QuantiFast Probe-based Assays in human, mouse, rat ABT1

    Additional mRNA sequence: 

    AB027258.1 BC048812.1 BC066313.1 

    10 DOTS entries:

    DT.415322  DT.100806016  DT.40228669  DT.100806004  DT.100806013  DT.121323758  DT.91756269  DT.95211608 
    DT.121323754  DT.454223 

    Selected AceView cDNA sequences (see all 261):

    CR590058 BU957265 AA598460 AI583692 BU741142 AA897258 BQ218007 BU839333 
    BU188987 CR613442 AA907132 BF111304 BM726847 AI207160 BQ682982 AI659897 
    BM803677 BM810656 AW297681 BE328097 BU179656 BM772523 BU632184 CB111790 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ABT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTTTTGTG
    ABT1 Expression
    About this image

    ABT1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ABT1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.254406
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ABT1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Abt11 , 5 activator of basal transcription 11, 5 78.83(n)1
    79.47(a)1
      13 (9.65 cM)5
    309461  NM_013924.31  NP_038952.11 
     234215395 
    lizard
    (Anolis carolinensis)
    Reptilia ABT16
    activator of basal transcription 1
    50(a)
    1 ↔ 1
    2(69678977-69684060)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC529392 similar to activator of basal transcription 73.38(n)    BC041500.1 
    zebrafish
    (Danio rerio)
    Actinopterygii abt11 activator of basal transcription 1 56.46(n)
    58.37(a)
      553568  NM_001020547.1  NP_001018383.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG327086
    CG415626
    (see all 6)
    --
    31(a)
    29(a)
    (see all 6)
    1 ↔ many
    1 ↔ many
    (see all 6)
    X(8979965-8980899)
    U(5467096-5467810)
    worm
    (Caenorhabditis elegans)
    Secernentea F57B10.86
    Protein F57B10.8 (F57B10.8) mRNA, complete cds
    26(a)
    1 ↔ 1
    I(6548644-6550447) WBGene00019005
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ESF2(YNR054C)4 Essential nucleolar protein involved in pre-18S rRNA more   --   14(724306-723356) 855790  NP_014452.1 


    ENSEMBL Gene Tree for ABT1 (if available)
    TreeFam Gene Tree for ABT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ABT1 gene

    Find genes that share paralogs with ABT1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ABT1
    PGOHUM00000245631


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ABT1 (see all 123)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs737390271,2
    C,F--26595196(+) GTTCCA/G/TTTTTT 1 -- us2k11WA 2
    rs69154071,2
    C,F--26595219(+) TCTGGG/ACCTGA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs350581681,2
    C--26595248(+) CGCAT-/GGTGCA 1 -- us2k10--------
    rs69155551,2
    C,F,A,H--26595267(+) ATTCAT/GGAATT 1 -- us2k135Minor allele frequency- G:0.31NA EA NS WA CSA 3274
    rs783103711,2
    C--26595308(+) ACCCTC/GAAAAT 1 -- us2k10--------
    rs38070281,2
    C,F--26595427(+) TTCATA/TTTTTT 1 -- us2k1 trp35Minor allele frequency- T:0.25NA WA CSA 8
    rs800145291,2
    --26595439(+) TTTTTG/TTCGGT 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs38070291,2
    C,F,A--26595446(+) CGGTTC/TCACGG 1 -- us2k114Minor allele frequency- T:0.34NA WA CSA EA 514
    rs1922031311,2
    --26595478(+) ATTGAC/TACTTG 1 -- us2k10--------
    rs1824671051,2
    --26595643(+) CAACAC/TGTGTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ABT1 (26597171 - 26600278 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ABT1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ABT1
    DNA2.0 Custom Variant and Variant Library Synthesis for ABT1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for ABT1:    
    About MalaCards
    spinocerebellar ataxia type 17    roberts syndrome    neuronal intranuclear inclusion disease

    1 disease from the University of Copenhagen DISEASES database for ABT1:
    Roberts syndrome

    Find genes that share disorders with ABT1           About GenesLikeMe

    6 Novoseek inferred disease relationships for ABT1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sca17 70.1 2 15193429 (1), 18043721 (1)
    spinocerebellar ataxias 48.8 1 15365789 (1)
    leukemia t-cell 23.7 1 1996321 (1)
    cancer 5.62 1 15337825 (1)
    shock 0 2 18028214 (1), 15977647 (1)
    tumors 0 1 7834749 (1)

    Genetic Association Database (GAD): ABT1
    Human Genome Epidemiology (HuGE) Navigator: ABT1 (1 document)

    Export disorders for ABT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ABT1 gene, integrated from 10 sources (see all 198):
    (articles sorted by number of sources associating them with ABT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth. (PubMed id 10648625)1, 2, 3 Oda T.... Muramatsu M.-A. (Mol. Cell. Biol. 2000)
    2. Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery. (PubMed id 19299493)1, 2 de Planell-Saguer M....Mourelatos Z. (Hum. Mol. Genet. 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. Protein phosphatase 1I^ isoforms linked interactions in the brain. (PubMed id 23080069)1 Esteves S.L....da Cruz e Silva E.F. (J. Mol. Neurosci. 2013)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29777 HGNC: 17369 AceView: ABT1 Ensembl:ENSG00000146109 euGenes: HUgn29777
    ECgene: ABT1 H-InvDB: ABT1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ABT1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ABT1 gene:
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    GeneCards and IP:
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