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Aliases for ABRACL Gene

Aliases for ABRACL Gene

  • ABRA C-Terminal Like 2 3 5
  • ABRA C-Terminal-Like Protein 3 4
  • C6orf115 3 4
  • Chromosome 6 Open Reading Frame 115 2
  • Costars Family Protein ABRACL 3
  • Costars 3
  • HSPC280 3
  • PRO2013 3

External Ids for ABRACL Gene

Previous HGNC Symbols for ABRACL Gene

  • C6orf115

Previous GeneCards Identifiers for ABRACL Gene

  • GC06P139349

Summaries for ABRACL Gene

GeneCards Summary for ABRACL Gene

ABRACL (ABRA C-Terminal Like) is a Protein Coding gene.

Additional gene information for ABRACL Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABRACL Gene

Genomics for ABRACL Gene

Regulatory Elements for ABRACL Gene

Enhancers for ABRACL Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H139131 1.6 Ensembl ENCODE dbSUPER 6.6 +105.9 105890 5.9 PKNOX1 ARNT ARID4B SIN3A ZNF143 ZNF207 FOS SP3 ZHX2 ZC3H11A ABRACL HECA TXLNB ECT2L GC06P139052
GH06H139124 1.3 Ensembl ENCODE dbSUPER 6.6 +97.3 97270 2.9 ELF3 RAD21 SCRT2 ZNF143 FOS RUNX3 ZNF654 CEBPB ELF1 REST ABRACL HECA GC06P139052
GH06H138957 1.2 Ensembl ENCODE dbSUPER 6.1 -70.4 -70369 1.8 ELF3 SOX6 MAX EBF1 PRDM6 ZNF316 IKZF1 HNF4A MLLT1 IKZF2 REPS1 ABRACL ENSG00000220600
GH06H139111 1.1 FANTOM5 ENCODE dbSUPER 6.5 +84.6 84647 3.6 OSR2 GATA3 ZSCAN4 FOXP2 SP7 HECA ECT2L LOC102723690 ABRACL REPS1 GC06P139052
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ABRACL on UCSC Golden Path with GeneCards custom track

Promoters for ABRACL Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000203824 618 2601 HDGF FOXA2 ARNT SIN3A GLI4 ZNF2 GLIS2 ELK1 ZNF143 ATF7

Genomic Locations for ABRACL Gene

Genomic Locations for ABRACL Gene
14,621 bases
Plus strand

Genomic View for ABRACL Gene

Genes around ABRACL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABRACL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABRACL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABRACL Gene

Proteins for ABRACL Gene

  • Protein details for ABRACL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Costars family protein ABRACL
    Protein Accession:
    Secondary Accessions:
    • Q5SZC8
    • Q9P0A1

    Protein attributes for ABRACL Gene

    81 amino acids
    Molecular mass:
    9056 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF28958.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ABRACL Gene

neXtProt entry for ABRACL Gene

Post-translational modifications for ABRACL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABRACL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ABRACL Gene

Domains & Families for ABRACL Gene

Gene Families for ABRACL Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for ABRACL Gene


Suggested Antigen Peptide Sequences for ABRACL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the costars family.
  • Belongs to the costars family.
genes like me logo Genes that share domains with ABRACL: view

Function for ABRACL Gene

genes like me logo Genes that share phenotypes with ABRACL: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ABRACL Gene

Localization for ABRACL Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ABRACL gene
Compartment Confidence
cytosol 4
nucleus 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ABRACL Gene

Pathways & Interactions for ABRACL Gene

SuperPathways for ABRACL Gene

No Data Available

Interacting Proteins for ABRACL Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: Q9P1F3-ABRAL_HUMAN ENSP00000356632 for ABRACL Gene via IID STRING

Gene Ontology (GO) - Biological Process for ABRACL Gene


No data available for Pathways by source and SIGNOR curated interactions for ABRACL Gene

Drugs & Compounds for ABRACL Gene

No Compound Related Data Available

Transcripts for ABRACL Gene


Unigene Clusters for ABRACL Gene

ABRA C-terminal like:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ABRACL Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b
SP1: -
SP2: -

Relevant External Links for ABRACL Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ABRACL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ABRACL Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ABRACL Gene

This gene is overexpressed in NK cells (9.3) and Oral epithelium (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ABRACL Gene

Protein tissue co-expression partners for ABRACL Gene

NURSA nuclear receptor signaling pathways regulating expression of ABRACL Gene:


SOURCE GeneReport for Unigene cluster for ABRACL Gene:


Evidence on tissue expression from TISSUES for ABRACL Gene

  • Nervous system(2.9)
  • Spleen(2)
genes like me logo Genes that share expression patterns with ABRACL: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ABRACL Gene

Orthologs for ABRACL Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABRACL Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ABRACL 33 34
  • 99.18 (n)
(Canis familiaris)
Mammalia ABRACL 33 34
  • 91.77 (n)
(Bos Taurus)
Mammalia ABRACL 34 33
  • 90.95 (n)
(Mus musculus)
Mammalia Abracl 16 34 33
  • 88.48 (n)
(Rattus norvegicus)
Mammalia Abracl 33
  • 87.24 (n)
(Ornithorhynchus anatinus)
Mammalia ABRACL 34
  • 86 (a)
(Monodelphis domestica)
Mammalia ABRACL 34
  • 83 (a)
(Gallus gallus)
Aves ABRACL 34
  • 84 (a)
C6ORF115 33
  • 80.66 (n)
(Anolis carolinensis)
Reptilia ABRACL 34
  • 84 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia abracl 33
  • 79.01 (n)
(Danio rerio)
Actinopterygii abracl 34 33
  • 69.14 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G33640 33
  • 65.38 (n)
(Oryza sativa)
Liliopsida Os03g0690000 33
  • 61.18 (n)
Species where no ortholog for ABRACL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ABRACL Gene

Gene Tree for ABRACL (if available)
Gene Tree for ABRACL (if available)

Paralogs for ABRACL Gene

(1) SIMAP similar genes for ABRACL Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ABRACL: view

No data available for Paralogs for ABRACL Gene

Variants for ABRACL Gene

Sequence variations from dbSNP and Humsavar for ABRACL Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000303029 -- 139,036,428(+) CTACT(A/T)TTCCC intron-variant
rs1000440422 -- 139,036,142(+) CACCA(G/T)GTTGG intron-variant
rs1000569400 -- 139,029,386(+) AGCCC(A/G)GGGCA intron-variant
rs1000640733 -- 139,037,626(+) CCACG(C/T)ATTTC intron-variant
rs1000676420 -- 139,035,466(+) ATCAT(A/G)CTGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ABRACL Gene

Variant ID Type Subtype PubMed ID
nsv510052 OTHER sequence alteration 20534489
nsv478447 CNV novel sequence insertion 20440878

Variation tolerance for ABRACL Gene

Residual Variation Intolerance Score: 45% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.19; 4.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ABRACL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABRACL Gene

Disorders for ABRACL Gene

Relevant External Links for ABRACL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ABRACL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABRACL Gene

Publications for ABRACL Gene

  1. Solution structure of the human HSPC280 protein. (PMID: 21082705) Lin J … Wang J (Protein science : a publication of the Protein Society 2011) 2 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K … Vandekerckhove J (Nature biotechnology 2003) 3 4 60
  4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang QH … Chen Z (Genome research 2000) 3 4 60
  5. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C … Emili A (Nature 2015) 3 60

Products for ABRACL Gene

Sources for ABRACL Gene

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