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Aliases for ABRACL Gene

Aliases for ABRACL Gene

  • ABRA C-Terminal Like 2 3 5
  • ABRA C-Terminal-Like Protein 3 4
  • C6orf115 3 4
  • Chromosome 6 Open Reading Frame 115 2
  • Costars 3
  • HSPC280 3
  • PRO2013 3

External Ids for ABRACL Gene

Previous HGNC Symbols for ABRACL Gene

  • C6orf115

Previous GeneCards Identifiers for ABRACL Gene

  • GC06P139349

Summaries for ABRACL Gene

GeneCards Summary for ABRACL Gene

ABRACL (ABRA C-Terminal Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABRACL Gene

Genomics for ABRACL Gene

Regulatory Elements for ABRACL Gene

Promoters for ABRACL Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ABRACL on UCSC Golden Path with GeneCards custom track

Genomic Location for ABRACL Gene

139,028,682 bp from pter
139,043,302 bp from pter
14,621 bases
Plus strand

Genomic View for ABRACL Gene

Genes around ABRACL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABRACL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABRACL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABRACL Gene

Proteins for ABRACL Gene

  • Protein details for ABRACL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Costars family protein ABRACL
    Protein Accession:
    Secondary Accessions:
    • Q5SZC8
    • Q9P0A1

    Protein attributes for ABRACL Gene

    81 amino acids
    Molecular mass:
    9056 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF28958.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ABRACL Gene

neXtProt entry for ABRACL Gene

Proteomics data for ABRACL Gene at MOPED

Post-translational modifications for ABRACL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABRACL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ABRACL Gene

Domains & Families for ABRACL Gene

Protein Domains for ABRACL Gene


Suggested Antigen Peptide Sequences for ABRACL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the costars family.
  • Belongs to the costars family.
genes like me logo Genes that share domains with ABRACL: view

No data available for Gene Families for ABRACL Gene

Function for ABRACL Gene

genes like me logo Genes that share phenotypes with ABRACL: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ABRACL Gene

Localization for ABRACL Gene

Subcellular locations from

Jensen Localization Image for ABRACL Gene COMPARTMENTS Subcellular localization image for ABRACL gene
Compartment Confidence
cytosol 4
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ABRACL Gene

Pathways & Interactions for ABRACL Gene

SuperPathways for ABRACL Gene

No Data Available

Interacting Proteins for ABRACL Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000356632 for ABRACL Gene via STRING

Gene Ontology (GO) - Biological Process for ABRACL Gene


No data available for Pathways by source and SIGNOR curated interactions for ABRACL Gene

Drugs & Compounds for ABRACL Gene

No Compound Related Data Available

Transcripts for ABRACL Gene


Unigene Clusters for ABRACL Gene

ABRA C-terminal like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ABRACL Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b
SP1: -
SP2: -

Relevant External Links for ABRACL Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ABRACL Gene

mRNA expression in normal human tissues for ABRACL Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ABRACL Gene

This gene is overexpressed in NK cells (9.3) and Oral epithelium (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ABRACL Gene

SOURCE GeneReport for Unigene cluster for ABRACL Gene Hs.600861

genes like me logo Genes that share expression patterns with ABRACL: view

Protein tissue co-expression partners for ABRACL Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABRACL Gene

Orthologs for ABRACL Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABRACL Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ABRACL 35
  • 90.95 (n)
  • 95.06 (a)
  • 95 (a)
(Canis familiaris)
Mammalia ABRACL 35
  • 91.77 (n)
  • 98.77 (a)
  • 99 (a)
(Mus musculus)
Mammalia Abracl 35
  • 88.48 (n)
  • 92.59 (a)
Abracl 16
Abracl 36
  • 93 (a)
(Pan troglodytes)
Mammalia ABRACL 35
  • 99.18 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Abracl 35
  • 87.24 (n)
  • 93.83 (a)
(Monodelphis domestica)
Mammalia ABRACL 36
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia ABRACL 36
  • 86 (a)
(Gallus gallus)
Aves C6ORF115 35
  • 80.66 (n)
  • 85.19 (a)
  • 84 (a)
(Anolis carolinensis)
Reptilia ABRACL 36
  • 84 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia abracl 35
  • 79.01 (n)
  • 90.12 (a)
(Danio rerio)
Actinopterygii abracl 35
  • 69.14 (n)
  • 80.25 (a)
abracl 36
  • 79 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G33640 35
  • 65.38 (n)
  • 70.51 (a)
(Oryza sativa)
Liliopsida Os03g0690000 35
  • 61.18 (n)
  • 68.35 (a)
Species with no ortholog for ABRACL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ABRACL Gene

Gene Tree for ABRACL (if available)
Gene Tree for ABRACL (if available)

Paralogs for ABRACL Gene

(1) SIMAP similar genes for ABRACL Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ABRACL: view

No data available for Paralogs for ABRACL Gene

Variants for ABRACL Gene

Sequence variations from dbSNP and Humsavar for ABRACL Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs2498642 -- 139,026,682(+) ctttc(C/T)ttttt upstream-variant-2KB
rs2498643 -- 139,039,936(+) ATAAA(A/G)ATAAA intron-variant
rs2504376 -- 139,028,784(+) TCCTT(C/G)GCCTC utr-variant-5-prime
rs2504377 -- 139,040,800(+) CTTCA(C/T)GCTGG intron-variant
rs4391279 -- 139,027,347(+) CGACT(A/G)TGAAA upstream-variant-2KB

Variation tolerance for ABRACL Gene

Residual Variation Intolerance Score: 45% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.19; 4.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ABRACL Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ABRACL Gene

Disorders for ABRACL Gene

Relevant External Links for ABRACL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ABRACL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABRACL Gene

Publications for ABRACL Gene

  1. Solution structure of the human HSPC280 protein. (PMID: 21082705) Lin J. … Wang J. (Protein Sci. 2011) 2 3 4 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. Costars, a Dictyostelium protein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motility. (PMID: 20940261) Pang T.L. … Chen M.Y. (J. Cell. Sci. 2010) 3
  4. A proteomic analysis of human hemodialysis fluid. (PMID: 15723814) Molina H. … Pandey A. (Mol. Cell Proteomics 2005) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for ABRACL Gene

Sources for ABRACL Gene

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