ABO Gene
protein-coding GIFtS: 61
GCID: GC09M136130
|
|
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;...
| |
Aliases
for ABO gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ABO Blood Group (Transferase A, Alpha 1-3-N-Acetylgalactosaminyltransferase;Transferase B, Alpha 1-3-Galactosyltransferase)1 2 | | ABO A3 Transferase2 | | A3GALNT1 2 | | ABO Glycosyltransferase2 | | A3GALT11 2 | | ABO Weak Transfer2 | | Fucosylglycoprotein 3-Alpha-Galactosyltransferase2 3 | | B(A) Alpha-1,3-Galactosyltransferase2 | | Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase2 3 | | Histo-Blood Group A2 Transferase2 | | Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase2 3 | | Histo-Blood Group ABO System Transferase2 | | Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase2 3 | | EC 2.4.1.373 | | Histo-Blood Group A Transferase2 3 | | EC 2.4.1.403 | | Histo-Blood Group B Transferase2 3 | | A Transferase3 | | NAGAT2 3 | | B Transferase3 | | GTB2 | | |
Export aliases for ABO gene to outside databasesPrevious GC identifers: GC09M127220 GC09M127687 GC09M129484 GC09M131407 GC09M133160 GC09M135120 GC09M105623 |
Summaries
for ABO gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABO:
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in anindividual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminusof the protein which results in a frameshift and translation of an almost entirely different protein. Individuals withthe A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen.Other minor alleles have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: BGAT_HUMAN, P16442Function: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves threecarbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts theH antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas Oindividuals lack such activity
Gene Wiki entry for ABO
|
Genomic Views
for ABO gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_035014.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABO gene promoter:
Sp1 MyoD IRF-7A CUTL1 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABO
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABO |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.2 Ensembl cytogenetic band: 9q34.2 HGNC cytogenetic band: 9q34.2ABO Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M136130: view genomic region
(about GC identifiers)
Start:
|
136,130,563 bp from pter |
End:
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136,150,630 bp from pter |
Size:
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20,068 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr9-,PATCHES 136,125,503-136,145,542 |
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Proteins
for ABO gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BGAT_HUMAN, P16442 (See
protein sequence)Recommended Name: Histo-blood group ABO system transferase Size: 354 amino acids; 40934 Da
Cofactor: Binds 1 manganese ion per subunit
Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid
6/83 PDB 3D structures from  and Proteopedia  for ABO (see all 83):1LZ0 (3D)
1LZ7 (3D)
1LZI (3D)
1LZJ (3D)
1R7T (3D)
1R7U (3D)
Secondary accessions: B0JDB9 O14758 Q14490 Q53I57 Q6ISD4 Q6KFZ2 Q70V27 Q99484 Q99485 Q9NY01 Q9UQ68Q9UQ69Explore the universe of human proteins at neXtProt for ABO: NX_P16442
Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P16442
ABO Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_065202.2
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
NAS | -- | | GO:0030173 | integral to Golgi membrane |
NAS | -- | | GO:0032580 | Golgi cisterna membrane |
IEA | -- |
ABO for ontologies About GeneDecksing
ABO Antibody Products:
Assay Products for ABO: |
Protein
Domains /
Families
for ABO gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABO for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P16442ProtoNet protein and cluster: P16442 1 Blocks protein family: IPB005076 Glycosyl transferase
UniProtKB/Swiss-Prot: BGAT_HUMAN, P16442Domain: The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphategroup of UDP and may also have a role in catalysisSimilarity: Belongs to the glycosyltransferase 6 family |
Function
for ABO gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BGAT_HUMAN, P16442Function: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves threecarbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts theH antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas Oindividuals lack such activityCatalytic activity: UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1->2)-D-galactose = UDP +glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactoseCatalytic activity: UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP +alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-REnzyme Numbers (IUBMB): EC 2.4.1.371 EC 2.4.1.401
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABO (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABO
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ABO (NM_020469) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABO | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABO |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABO |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004380 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity |
NAS | -- | | GO:0004381 | fucosylgalactoside 3-alpha-galactosyltransferase activity |
NAS | -- | | GO:0046872 | metal ion binding |
IEA | -- |
ABO for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ABO:
|
Pathways & Interactions
for ABO gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glycosphingolipid biosynthesis - lacto and neolacto series | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Kegg Pathways (Kegg details for ABO):
UniProtKB/Swiss-Prot: BGAT_HUMAN, P16442Pathway: Protein modification; protein glycosylation
ABO for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABO
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006486 | protein glycosylation |
NAS | -- |
ABO for ontologies About GeneDecksing
|
Drugs & Compounds
for ABO gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ABO for compounds About GeneDecksing
 Browse Tocris compounds for ABO
5 HMDB Compounds for ABO About this table
10/13 DrugBank Compounds for ABO (see all 13) About this table
10/12 Novoseek chemical compound relationships for ABO gene (see all 12) About this table
Search CenterWatch for drugs/clinical trials and news about ABO / BGAT
|
Transcripts
for ABO gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABO gene: NM_020469.2 Unigene Cluster for ABO: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) Hs.654423 [show with all ESTs]Unigene Representative Sequence: AK1245872 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000453660(lincRNA)(uc004cda.1 uc010naf.1 uc011mcz.1 uc010nag.1)
ENST00000538324(lincRNA)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABO (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABO
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ABO (NM_020469) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABO | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABO |
Additional cDNA sequence: AF134412.1 AF134413.1 AF134414.1 AF134415.1 AF134416.1 AK095379.1 AK124587.1 AK302203.1 AY579471.1 AY727862.1 BC069595.1 BC069605.1 BC069814.1 BC111575.1 DQ139865.1 FR691751.1 FR691752.1 J05175.1 JN791441.1 JX519569.1 JX519570.1 U15197.1 5 DOTS entries: DT.211476 DT.428863 DT.102822581 DT.95202884 DT.121166283 24/29 AceView cDNA sequences (see all 29): U15197 BX485027 AI476688 J05175 AF134413 BC069814 AW302156 AF134415 AA431249 AF134416 BC069605 AF134412 NM_020469 AA595771 BP354524 BC069595 BF448058 AF134414 BP351450 S44054 BP352662 AV761252 AA931083 BP351212
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ABO About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | · | 8c |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | |
| SP3: | | | - | | - | | | | | | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ABO
|
Expression
for ABO gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABO expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCTCAGGCC
About this image
Genevestigator expression for ABO
SOURCE GeneReport for Unigene cluster: Hs.654423
SABiosciences Custom PCR Arrays for ABO
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABO
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABO | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABO | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABO | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABO |
Orthologs
for ABO gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ABO gene from 2/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Abo1 , 5 |
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, more1, 5 |
75.56(n)1
75.15(a)1 |
|
2 (19.06 cM)5
809081 NM_030718.41 NP_109643.31
268425035 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
BX710344.12 |
-- |
74.06(n) |
|
BX710344.1 |
ENSEMBL Gene Tree for ABO (if available)
TreeFam Gene Tree for ABO (if available) |
Paralogs
for ABO gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ABO gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: BGAT_HUMAN, P16442Polymorphism: The sequence shown is that of the A transferase. The B form differs by a few residues substitutions. TheO phenotype results from a single base frameshift in the N-terminal extremity of the gene, resulting in a severlytruncated protein without catalytic activity
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABO (136130563 - 136150630 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for ABO
7 CNVs: 29809 38736 65542 53331 10311 52737 29808
1 Indel: 13207
Human Gene Mutation Database (HGMD): ABO
Locus Specific Mutation Databases (LSDB): ABO
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ABO gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABO for disorders About GeneDecksing
OMIM gene information: 110300
OMIM disorders: --
20/50  diseases for ABO (see all 50): About MalaCardsblood group incompatibility nail-patella syndrome plasmodium falciparum malaria pre-eclampsia
atrophic gastritis congenital muscular dystrophy muscular dystrophy cystic fibrosis lung disease
oral squamous cell carcinoma peptic ulcer fatty liver disease cystic fibrosis
squamous cell carcinoma myeloid leukemia exostosis chronic myeloid leukemia
smallpox calcinosis bleeding disorder myocardial infarction
4 diseases from the University of Copenhagen DISEASES database for ABO:Malaria Von Willebrand's disease Blood group incompatibility Peptic ulcer 7 Novoseek disease relationships for ABO gene About this table
Genetic Association Database (GAD): ABO
Human Genome Epidemiology (HuGE) Navigator: ABO (120 documents)
Export disorders for ABO gene to outside databases
|
Publications
for ABO gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABO gene, integrated from 9 sources (see all 273):
(articles sorted by number of sources associating them with ABO) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of DNA complementary to human UDP- GalNAc: Fuc alpha 1-->2Gal alpha 1-->3GalNAc transferase (histo-blood group A transferase) mRNA. (PubMed id 2104828)1, 2, 9 Yamamoto F.... Hakomori S. (1990)
- Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif. (PubMed id 17259183)1, 2, 9 Persson M.... Olsson M.L. (2007)
- A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase. (PubMed id 12529355)1, 2, 9 Marcus S.L.... Palcic M.M. (2003)
- The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases. (PubMed id 12972418)2, 7, 9 Nguyen H.P.... Evans S.V. (2003)
- Sugar-nucleotide donor specificity of histo-blood group A and B transferases is based on amino acid substitutions. (PubMed id 2121736)1, 2, 9 Yamamoto F. and Hakomori S. (1990)
- The structural basis for specificity in human ABO(H) blood group biosynthesis. (PubMed id 12198488)1, 2, 9 Patenaude S.I.... Evans S.V. (2002)
- Molecular genetic basis of the histo-blood group ABO system. (PubMed id 2333095)1, 2, 9 Yamamoto F.... Hakomori S. (1990)
- Weak blood group B phenotypes may be caused by variations in the CCAAT-binding factor/NF-Y enhancer region of the ABO gene. (PubMed id 17764507)1, 2 Seltsam A....Blasczyk R. (2007)
- Relationship between ABO and Secretor genotype with plasma levels of factor VIII and von Willebrand factor in thrombosis patients and control individuals. (PubMed id 15606555)1, 4 Schleef M....Spannagl M. (2005)
- The ABO blood group genotype and factor VIII levels as independent risk factors for venous thromboembolism. (PubMed id 15735796)1, 4 Tirado I....Fontcuberta J. (2005)
|
External Searches for ABO gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ABO gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABO gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABO gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ABO | Pharmacogenomics, SNPs, Pathways | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/ | | SeattleSNPs | http://pga.gs.washington.edu/data/abo/ | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_450 | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_502 |
|
| | |
About This Section
| Patent Information for ABO gene:
Search GeneIP for patents involving ABO
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ABO gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for ABO | | OriGene shRNA RFP for ABO | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABO | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABO | | | OriGene Protein Over-expression Lysate for ABO | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABO | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABO | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABO | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ABO | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABO | | OriGene Custom Protein Services for ABO | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABO | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABO | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABO | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABO | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABO | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABO |
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| | | | Search Tocris compounds for ABO |
| |  |  |  |  | | | | | | Recombinant Protein for ABO |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABO |
|  |  |  | | | | ThermoFisher Antibodies for ABO |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABO |
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