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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ABLIM3 Gene

protein-coding GIFtS: 57
GCID: GC05P148501

actin binding LIM protein family, member 3

Explore 1 disease affiliated with
ABLIM3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Actin Binding LIM Protein Family, Member 3¹ ²
KIAA0843¹ ³
Actin-Binding LIM Protein Family Member 3² ³
AbLIM-3¹
Actin-Binding LIM Protein 3²

External Ids:	HGNC: 29132¹	Entrez Gene: 22885²	Ensembl: ENSG00000173210⁷	OMIM: 611305⁵	UniProtKB: O94929³

Export aliases for ABLIM3 gene to outside databases

Previous GC identifers: GC05P148549 GC05P143667

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABLIM3:

The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such

as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer (Krupp et al., 2006 (PubMed

16328021)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: ABLM3_HUMAN, O94929

Function: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity

Gene Wiki entry for ABLIM3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NC_018916.1 NT_029289.11

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ABLIM3 gene promoter:
RFX1 Sox5 AML1a LCR-F1 E47 POU2F1 POU2F1a POU2F1b Hand1 POU2F1c
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ABLIM3 promoter sequence

Search SABiosciences Chromatin IP Primers for ABLIM3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABLIM3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q32 Ensembl cytogenetic band: 5q32 HGNC cytogenetic band: 5q33.1

ABLIM3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABLIM3 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P148501: view genomic region (about GC identifiers)

Start:	148,521,046 bp from pter	End:	148,640,105 bp from pter
Size:	119,060 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ABLM3_HUMAN, O94929 (See protein sequence)

Recommended Name: Actin-binding LIM protein 3

Size: 683 amino acids; 77802 Da

Subunit: Directly interacts with F-actin and ABRA

Subcellular location: Cytoplasm (By similarity)

Sequence caution: Sequence=BAA74866.2; Type=Erroneous initiation;

2 PDB 3D structures from and Proteopedia for ABLIM3:

1UJS (3D)

2DJ7 (3D)

Secondary accessions: A8K121 Q19VH3 Q658S1 Q68CI5 Q9BV32

Alternative splicing: 4 isoforms: O94929-1 O94929-2 O94929-3 O94929-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ABLIM3: NX_O94929

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O94929

ABLIM3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055760.1

ENSEMBL proteins:

ENSP00000315841 ENSP00000310309 ENSP00000425394 ENSP00000421002 ENSP00000421183

ENSP00000420855 ENSP00000430150 ENSP00000348938

Reactome Protein details: O94929
Human Recombinant Protein Products for ABLIM3:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Novus Biologicals ABLIM3 Protein Novus Biologicals ABLIM3 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ABLIM3

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	NAS	--

ABLIM3 for ontologies About GeneDecksing

ABLIM3 Antibody Products:

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	Uscn Antibodies for ABLIM3
	Search ThermoFisher Antibodies for ABLIM3

Assay Products for ABLIM3:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for ABLIM3
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	Uscn ELISAs and CLIAs for ABLIM3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ABLIM3 for domains About GeneDecksing

2 InterPro domains/families:

IPR001781 Znf_LIM

IPR003128 Villin_headpiece

Graphical View of Domain Structure for InterPro Entry O94929

ProtoNet protein and cluster: O94929

1 Blocks protein family: IPB001781 Zn-binding protein

UniProtKB/Swiss-Prot: ABLM3_HUMAN, O94929

Similarity: Contains 1 HP (headpiece) domain

Similarity: Contains 4 LIM zinc-binding domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ABLM3_HUMAN, O94929

Function: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--
GO:0008270	zinc ion binding	NAS	--

ABLIM3 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ABLIM3:

Increased 8N DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ABLIM3

miRNA Products:		OriGene 3'-UTR Clone: ABLIM3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABLIM3
		8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate ABLIM3 (see all 28):
		hsa-miR-3685 hsa-miR-4311 hsa-miR-188-5p hsa-miR-3660 hsa-miR-605 hsa-miR-548s hsa-miR-410 hsa-miR-508-3p

		SwitchGear 3'UTR luciferase reporter plasmid: ABLIM3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABLIM3 (see all 4) OriGene shRNA RFP: ABLIM3 OriGene siRNA: ABLIM3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABLIM3
		Sirion Biotech Custom design and validation of potent shRNA sequences against ABLIM3

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for ABLIM3
			Sirion Biotech Customized adenovirus for overexpression of ABLIM3 Sirion Biotech Customized adenovirus for potent knockdown of ABLIM3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABLIM3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABLIM3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ABLIM3 (NM_014945)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABLIM3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABLIM3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ABLIM3
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		Sirion Biotech Customized stable knockdown cell line services for ABLIM3 Sirion Biotech Customized inducible knockdown cell line services for ABLIM3 Sirion Biotech Customized stable overexpressing cell line services for ABLIM3 Sirion Biotech Customized inducible overexpressing cell line services for ABLIM3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABLIM3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Axon guidance

Axon guidance

1.00

Developmental Biology

0.69

Netrin-1 signaling

Netrin-1 signaling

1.00

DCC mediated attractive signaling

0.33

Netrin Signaling

Netrin Signaling

1.00

Axon guidance

Axon guidance

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ABLIM3

Netrin Signaling

4 Reactome Pathways for ABLIM3

	Developmental Biology
	Netrin-1 signaling
	DCC mediated attractive signaling
	Axon guidance

1 Kegg Pathway (Kegg details for ABLIM3):

Axon guidance

ABLIM3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ABLIM3

STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

5/13 Interacting proteins for ABLIM3 (O94929³ ENSP00000310309⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 13)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ACTC1	P68032³, ENSP00000290378⁴	I2D: score=2 STRING: ENSP00000290378
GRB2	P62993³, ENSP00000339007⁴	I2D: score=1 STRING: ENSP00000339007
ABLIM1	ENSP00000338190⁴	STRING: ENSP00000338190
ABLIM2	ENSP00000393511⁴	STRING: ENSP00000393511
NTN1	ENSP00000173229⁴	STRING: ENSP00000173229

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007010	cytoskeleton organization	IEA	--
GO:0007411	axon guidance	TAS	--
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IEA	--

ABLIM3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ABLIM3
Search CenterWatch for drugs/clinical trials and news about ABLIM3 / ABLM3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ABLIM3 gene:

NM_014945.2

Unigene Cluster for ABLIM3:

Actin binding LIM protein family, member 3

Hs.49688 [show with all ESTs]

Unigene Representative Sequence: AK225769

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000326685(uc003lqd.1 uc003lqe.1) ENST00000309868(uc003lpy.2 uc003lqc.1)

ENST00000506113(uc003lpz.1 uc003lqa.1 uc003lqb.3) ENST00000515171

ENST00000504238(uc003lqf.3) ENST00000508983 ENST00000515796 ENST00000514212

ENST00000519549 ENST00000517451 ENST00000502855 ENST00000356541

miRNA Products:		OriGene 3'-UTR Clone: ABLIM3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABLIM3
		8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate ABLIM3 (see all 28):
		hsa-miR-3685 hsa-miR-4311 hsa-miR-188-5p hsa-miR-3660 hsa-miR-605 hsa-miR-548s hsa-miR-410 hsa-miR-508-3p

		SwitchGear 3'UTR luciferase reporter plasmid: ABLIM3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABLIM3 (see all 4) OriGene shRNA RFP: ABLIM3 OriGene siRNA: ABLIM3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABLIM3
		Sirion Biotech Custom design and validation of potent shRNA sequences against ABLIM3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABLIM3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABLIM3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ABLIM3 (NM_014945)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABLIM3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABLIM3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABLIM3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ABLIM3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABLIM3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABLIM3

Additional cDNA sequence:

AB020650.1 AB075881.1 AK225769.1 AK289736.1 AL833021.1 BC001665.2 BC014463.1 DQ413174.1

11 DOTS entries:

DT.100025415 DT.412336 DT.101977530 DT.95212938 DT.100751551 DT.99963960 DT.120864719 DT.91693987

DT.99959096 DT.101969107 DT.120864799

3 AceView cDNA sequences:

AL701274 AL603450 BX474446

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ABLIM3 (see all 7) About this scheme

ExUns:	1	^	2a	·	2b	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12	^	13a	·	13b	·	13c	^	14	^	15a	·	15b	·	15c	^	16a	·	16b	^	17	^
SP1:			-												-																												-		-		-
SP2:															-														-		-								-		-		-		-		-
SP3:																																							-		-		-		-		-
SP4:
SP5:																																							-						-		-

ExUns:	18	^	19	^	20	^	21	^	22	^	23	^	24
SP1:
SP2:											-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ABLIM3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ABLIM3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAGTTGCCT

About this image

ABLIM3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Antral Follicle

Cumulus Cells

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)

Endothelium

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

See ABLIM3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABLIM3

SOURCE GeneReport for Unigene cluster: Hs.49688

UniProtKB/Swiss-Prot: ABLM3_HUMAN, O94929

Tissue specificity: Expressed predominantly in heart and brain

SABiosciences Custom PCR Arrays for ABLIM3

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		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ABLIM3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABLIM3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABLIM3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABLIM3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ABLIM3 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ABLIM3¹	actin binding LIM protein family, member 3	83.85(n) 89.75(a)		416201 XM_414527.3 XP_414527.3
lizard (Anolis carolinensis)	Reptilia	ABLIM3⁶	--	89(a)	1 ↔ 1	2(122890995-122974846)
zebrafish (Danio rerio)	Actinopterygii	si:dkey-23o10.3⁶ ablim3⁶ (see all 3)	actin binding LIM protein family, member 3 (see all 3)	74(a) 74(a) (see all 3)	1 ↔ many 1 ↔ many (see all 3)	14(43528737-43639005) 14(35765305-35926930)
fruit fly (Drosophila melanogaster)	Insecta	Unc-115a⁶ Unc-115b⁶	--	27(a) 24(a)	many ↔ many many ↔ many	3R(5520444-5531165) 3R(5512782-5518497)
worm (Caenorhabditis elegans)	Secernentea	unc-115⁶	UNCoordinated family member (unc-115)	24(a)	1 → many	X(10146833-10152726)

ENSEMBL Gene Tree for ABLIM3 (if available)
TreeFam Gene Tree for ABLIM3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ABLIM3 gene

LIMS1² LIMS3L² FHL5² LDB3² LPXN² ABLIM2² PDLIM5² ENSG00000257207²

LIMS2² FHL2² ABLIM1² PDLIM7² EPB49² FHL3² FHL1² TGFB1I1²

LIMS3² PXN²

8 SIMAP similar genes for ABLIM3 using alignment to 2 protein entries: ABLM3_HUMAN (see all proteins):

LIMS1 ABLIM1 ABLIM2 LIMS2 PDLIM5 LDB3

WTIP LMO2

ABLIM3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs3839234^1,2	C	--	143743171(-)	`GAAGC-/CAAGAT`	1	--	int¹		2		NA CSA	4
rs201655783^1,2	C	--	143743171(+)	`ATCTTG/TGCTTC`	1	--	int¹		0	--	--	--	--
rs180981394^1,2		--	148519126(+)	`AAAATG/TTAGAG`	1	--	us2k¹		0	--	--	--	--
rs4291001^1,2	C,F,A,H	--	148519187(+)	`AAGCTG/ATTTTA`	1	--	us2k¹		28		NS EA NA WA CSA	2778
rs184337698^1,2		--	148519293(+)	`TTGGAA/GGTATC`	1	--	us2k¹		0	--	--	--	--
rs190449631^1,2		--	148519304(+)	`TCAGGC/TGTTTG`	1	--	us2k¹		0	--	--	--	--
rs117489712^1,2	F	--	148519373(+)	`CCCCAT/CTGGAC`	1	--	us2k¹		1		EA	120
rs114154234^1,2	C,F	--	148519378(+)	`TTGGAC/AAAAAT`	1	--	us2k¹		1		WA	118
rs143161699^1,2		--	148519493(+)	`CATCAA/CCTCAT`	1	--	us2k¹		0	--	--	--	--
rs144708032^1,2		--	148519595(+)	`CCATGC/TGCTCT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ABLIM3 (148521046 - 148640105 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for ABLIM3
2 CNVs: 99320 51589
2 Indels: 46789 46788

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABLIM3

DNA2.0 Custom Variant and Variant Library Synthesis for ABLIM3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ABLIM3 for disorders           About GeneDecksing

OMIM gene information: 611305    OMIM disorders: --

1 disease for ABLIM3:    About MalaCards

hepatoblastoma

Export disorders for ABLIM3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ABLIM3 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with ABLIM3)

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Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. (PubMed id 17194709)^{1, 2} Barrientos T.... Frey N. (2007)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)^{1, 2} Yamada S....Nakagawara A. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)^{1, 2} Nagase T....Ohara O. (1998)
Actin binding LIM protein 3 (abLIM3). (PubMed id 16328021)^{1, 9} Krupp M....Teufel A. (2006)
Phosphoproteome of resting human platelets. (PubMed id 18088087)² Zahedi R.P.... Sickmann A. (2008)
Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography. (PubMed id 18318008)² Han G.... Gu J. (2008)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The LIFEdb database in 2006. (PubMed id 16381901)¹ Mehrle A....Wiemann S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 22885	HGNC: 29132	AceView: ABLIM3	Ensembl:ENSG00000173210	euGenes: HUgn22885
ECgene: ABLIM3	Kegg: 22885	H-InvDB: ABLIM3

(According to HUGE)
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HUGE: KIAA0843

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ABLIM3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ABLIM3 gene
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Patent Information for ABLIM3 gene:
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ABLIM3 Gene

actin binding LIM protein family, member 3

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ABLIM3 Gene

actin binding LIM protein family, member 3

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