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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ABLIM1 Gene

protein-coding   GIFtS: 63
GCID: GC10M116190

Actin Binding LIM Protein 1


(Previous symbols: LIMAB1, ABLIM)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Actin Binding LIM Protein 11 2     Actin-Binding Double-Zinc-Finger Protein2
LIMAB11 2 3 5     Actin-Binding LIM Protein 12
ABLIM1 2 3     KIAA00593
Actin-Binding LIM Protein Family Member 12 3     Limatin3
abLIM-12 3     Actin-Binding Double Zinc Finger Protein3
LIMATIN2     

External Ids:    HGNC: 781   Entrez Gene: 39832   Ensembl: ENSG000000992047   OMIM: 6023305   UniProtKB: O146393   

Export aliases for ABLIM1 gene to outside databases

Previous GC identifers: GC10M115109 GC10M115434 GC10M116322 GC10M115855 GC10M116180 GC10M109817


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABLIM1 Gene:
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to
erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental
pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein
interactions. The protein encoded by this gene could mediate such interactions between actin filaments and
cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ABLIM1 Gene: 
ABLIM1 (actin binding LIM protein 1) is a protein-coding gene. Diseases associated with ABLIM1 include corneal neovascularization, and alcohol dependence, and among its related super-pathways are Axon guidance and DCC mediated attractive signaling. GO annotations related to this gene include actin binding and zinc ion binding. An important paralog of this gene is ABLIM3.

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639
Function: May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been
suggested to play a role in axon guidance

Gene Wiki entry for ABLIM1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ABLIM1 gene promoter:
         AhR   SRF   SRF (504 AA)   Lmo2   LCR-F1   C/EBPalpha   YY1   Arnt   AREB6   IRF-7A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABLIM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ABLIM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABLIM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q25

ABLIM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABLIM1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M116190:  view genomic region     (about GC identifiers)

Start:
116,190,869 bp from pter      End:
116,444,762 bp from pter
Size:
253,894 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639 (See protein sequence)
Recommended Name: Actin-binding LIM protein 1  
Size: 778 amino acids; 87688 Da
Subunit: Binds F-actin. Interacts with ABRA
Subcellular location: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associated with the
cytoskeleton (By similarity)
Sequence caution: Sequence=BAA06681.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NI16 A6NJ06 A8MXA9 Q15039 Q5JVV1 Q5JVV2 Q5T6N3 Q5T6N5 Q68CQ9 Q9BUP1
Alternative splicing: 5 isoforms:  O14639-1   O14639-2   O14639-3   O14639-4   O14639-5   

Explore the universe of human proteins at neXtProt for ABLIM1: NX_O14639

Explore proteomics data for ABLIM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14639

  • ABLIM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ABLIM1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001003407.1  NP_001003408.1  NP_002304.3  NP_006711.3  

    ENSEMBL proteins: 
     ENSP00000376679   ENSP00000376682   ENSP00000358257   ENSP00000358260   ENSP00000277895  
     ENSP00000414154   ENSP00000400934   ENSP00000433629   ENSP00000358256   ENSP00000358270  
    Reactome Protein details: O14639
    Human Recombinant Protein Products for ABLIM1: 
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    Cloud-Clone Corp. Proteins for ABLIM1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0015629actin cytoskeleton TAS9245787

    ABLIM1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001781 Znf_LIM
     IPR003128 Villin_headpiece

    Graphical View of Domain Structure for InterPro Entry O14639

    ProtoNet protein and cluster: O14639

    2 Blocks protein domains:
    IPB001781 Zn-binding protein
    IPB003128 Villin headpiece


    UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639
    Similarity: Contains 1 HP (headpiece) domain
    Similarity: Contains 4 LIM zinc-binding domains


    ABLIM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABLM1_HUMAN, O14639
    Function: May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been
    suggested to play a role in axon guidance

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005515protein binding IPI16189514
    GO:0008270zinc ion binding IEA--
         
    ABLIM1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ABLIM1:
     Increased gamma-H2AX phosphory  Increased homologous recombina 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Ablim1):
     normal 

    ABLIM1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ablim1tm1Lex for ABLIM1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ABLIM1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ABLIM1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Axon guidance
    Axon guidance0.69
    Developmental Biology0.69
    2Netrin-1 signaling
    DCC mediated attractive signaling0.33
    Netrin-1 signaling0.33
    3Netrin Signaling
    Netrin Signaling
    4Axon guidance
    Axon guidance

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ABLIM1
        Netrin Signaling


    4        Reactome Pathways for ABLIM1
        Developmental Biology
    Netrin-1 signaling
    DCC mediated attractive signaling
    Axon guidance


    1         Kegg Pathway  (Kegg details for ABLIM1):
        Axon guidance


    ABLIM1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABLIM1

    5/21 Interacting proteins for ABLIM1 (O146391, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LDOC1O957511, 2, 3EBI-487024,EBI-740738 MINT-67267 I2D: score=6 
    BEGAINQ9BUH82, 3MINT-66438 I2D: score=5 
    CALCOCO2Q131372, 3MINT-67707 I2D: score=5 
    GOLGA2Q083792, 3MINT-66414 I2D: score=5 
    HOOK2Q96ED92, 3MINT-68094 I2D: score=5 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization IEA--
    GO:0007411axon guidance TAS--
    GO:0007601visual perception TAS9245787
    GO:0009887organ morphogenesis TAS9245787
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ----

    ABLIM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ABLIM1 (ABLM1)

    Search CenterWatch for drugs/clinical trials and news about ABLIM1 / ABLM1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ABLIM1 gene (4 alternative transcripts): 
    NM_001003407.1  NM_001003408.1  NM_002313.5  NM_006720.3  

    Unigene Clusters for ABLIM1:

    Actin binding LIM protein 1
    Hs.438236  [show with all ESTs], Hs.538331
    Unigene Representative Sequences: NM_001003408, AK054890
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392952(uc021pyu.1) ENST00000392955 ENST00000369253 ENST00000369256(uc021pze.1)
    ENST00000277895(uc021pzd.1) ENST00000485570 ENST00000440467 ENST00000428430
    ENST00000466400 ENST00000481974 ENST00000477638(uc001lbz.1) ENST00000533213(uc021pyy.1 uc021pyz.1 uc021pzf.1)
    ENST00000369252(uc021pza.1) ENST00000369266(uc021pyv.1 uc021pzb.1 uc021pzc.1)


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    Additional mRNA sequence: AK054890.1 

    24/28 DOTS entries (see all 28):

    DT.95113279  DT.95206861  DT.95228019  DT.101984191  DT.100798559  DT.95228045  DT.100798557  DT.121288101 
    DT.121288169  DT.95228040  DT.100798556  DT.95299536  DT.100798561  DT.121288094  DT.40116746  DT.95147880 
    DT.40276377  DT.95228020  DT.95320564  DT.100008480  DT.91976084  DT.99939110  DT.121288229  DT.121288243 

    1 AceView cDNA sequence:

    AK054890 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ABLIM1 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a ·
    SP1:              -           -                                         -     -     -     -                                                                 -   
    SP2:              -           -                                         -     -     -     -                 -                                               -   
    SP3:                                                                                      -                                               -                 -   
    SP4:                                                                                      -                 -     -                       -                 -   
    SP5:                                                                                      -                 -                                                   

    ExUns: 19b ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for ABLIM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ABLIM1 expression in normal human tissues (normalized intensities)      ABLIM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTGTGTGTA
    ABLIM1 Expression
    About this image


    ABLIM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/12 selected tissues (see all 12) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 6 entries
             T Helper Cells Thymus
             Cord Blood Pan-T Cells   
             cd8+ t cell   
     
     Thymus (Hematopoietic System)    fully expand to see all 3 entries
             T Helper Cells Thymus
     
     Uncategorized (Uncategorized)    fully expand to see all 3 entries
             PureStem Progenitor ES-263
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 3 entries
             Cord Blood Pan-T Cells   
     
     Endothelium (Cardiovascular System)    fully expand to see all 3 entries
             Human Umbilical Vein Endothelial Cells (HUVEC) (ScienceCell)   

    See ABLIM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ABLIM1

    SOURCE GeneReport for Unigene clusters: Hs.438236 Hs.538331

    UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639
    Tissue specificity: Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the
    inner segment and in the outer plexiform layers

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ABLIM1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ablim11 , 5 actin-binding LIM protein 11, 5 87.8(n)1
    91.75(a)1
      19 (52.09 cM)5
    2262511  NM_178688.31  NP_848803.31 
     570327335 
    chicken
    (Gallus gallus)
    Aves ABLIM11 actin binding LIM protein 1 84.3(n)
    93.04(a)
      423911  NM_001159363.1  NP_001152835.1 
    lizard
    (Anolis carolinensis)
    Reptilia ABLIM16
    actin binding LIM protein 1
    78(a)
    1 ↔ 1
    GL343206.1(3960229-4152149)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.285132 Xenopus laevis transcribed sequence with weak similarity more 78.15(n)    BJ074832.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ablim1a1 actin binding LIM protein 1a 73.24(n)
    76.89(a)
      100003558  NM_001114316.1  NP_001107788.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Unc-115a1 CG31352-PA 50.94(n)
    44.97(a)
      261629  NM_001170103.1  NP_001163574.1 
    worm
    (Caenorhabditis elegans)
    Secernentea unc-1151 Protein UNC-115 47.75(n)
    39.19(a)
      181227  NM_001029371.2  NP_001024542.1 


    ENSEMBL Gene Tree for ABLIM1 (if available)
    TreeFam Gene Tree for ABLIM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ABLIM1 gene
    ABLIM32  LIMS12  LIMS3L2  DMTN2  LDB32  FHL52  LPXN2  PDLIM52  
    ABLIM22  ENSG000002572072  LIMS22  FHL22  PDLIM72  FHL32  FHL12  LIMS32  
    TGFB1I12  PXN2  
    18/19 SIMAP similar genes for ABLIM1 using alignment to 9 protein entries:     ABLM1_HUMAN (see all proteins) (see all similar genes):
    ABLIM3    LHx4    CRIP1    ABLIM2    LHX2    LHX3
    CRIP2    LASP1    LIMS1    ISL2    LHX8    LMO1
    DMTN    AJUBA    LHX4    LMO3    LIMK2    LIMS2

    ABLIM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5404 SNPs in ABLIM1 are shown (see all 5404)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs599477051,2
    C--109820817(+) CACAC-/ACACACAC/
    ACACACACACAC
    ACACG
    8 -- ut311NA 2
    rs1119228201,2
    C--109854916(+) AGGCGT/-CCGCC 4 -- int11Minor allele frequency- -:0.00CSA 2
    rs19697271,2
    C--109854917(-) TGGCGA/G/TCGCCT 4 -- int11NA 2
    rs339413311,2
    C--109854918(+) GGCGC-/A/TCGCCA 4 -- int10--------
    rs32156981,2
    C--109860092(-) AAAAAA/-TTCTT 4 -- int1 trp32Minor allele frequency- -:0.25NA 4
    rs1416183821,2
    C--109863147(+) CTCAA-/AATAATAA 4 -- int10--------
    rs2020148421,2
    C--109877509(+) TGTGTA/GTATAT 4 -- int10--------
    rs2008563381,2
    C--109928163(+) CACACA/TCTCAC 3 -- int10--------
    rs577563341,2
    C--109928845(+) AGAAGGAGGAA  
      GAAG
    /-
    AAGAA
    3 -- int11Minor allele frequency- -:0.00NA 2
    rs802448311,2
    C--109933412(+) ACATTA/TAAAAA 3 -- int11Minor allele frequency- T:0.00NA 2

    HapMap Linkage Disequilibrium report for ABLIM1 (116190869 - 116440869 bp, first 250kb of ABLIM1)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ABLIM1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2676795CNV Deletion23128226
    esv2741184CNV Deletion23290073
    nsv528140CNV Loss19592680
    esv26785CNV Loss19812545
    nsv7211OTHER Inversion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602330    OMIM disorders: --

    6 diseases for ABLIM1:    About MalaCards
    corneal neovascularization    alcohol dependence    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    alcoholism    alzheimer's disease


    ABLIM1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    1 Novoseek inferred disease relationship for ABLIM1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cancer 0 3 16328021 (1), 9417918 (1)

    Genetic Association Database (GAD): ABLIM1
    Human Genome Epidemiology (HuGE) Navigator: ABLIM1 (3 documents)

    Export disorders for ABLIM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ABLIM1 gene, integrated from 9 sources (see all 44):
    (articles sorted by number of sources associating them with ABLIM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein. (PubMed id 9245787)1, 2, 3, 9 Roof D.J.... Li T. (1997)
    2. A genome-wide search for loci interacting with known p rostate cancer risk-associated genetic variants. (PubMed id 22219177)1, 4 Tao S....Sun J. (2012)
    3. Genome-wide searching of rare genetic variants in WTC CC data. (PubMed id 20549515)1, 4 Feng T. and Zhu X. (2010)
    4. Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. (PubMed id 17194709)1, 2 Barrientos T.... Frey N. (2007)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    6. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    7. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3983 HGNC: 78 AceView: ABLIM1.1 Ensembl:ENSG00000099204 euGenes: HUgn3983
    ECgene: ABLIM1 Kegg: 3983 H-InvDB: ABLIM1

    (According to HUGE)
    About This Section
    HUGE: KIAA0059

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ABLIM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ABLIM1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ABLIM1 gene:
    Search GeneIP for patents involving ABLIM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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