Aliases for ABLIM1 Gene
External Ids for ABLIM1 Gene
Previous HGNC Symbols for ABLIM1 Gene
Previous GeneCards Identifiers for ABLIM1 Gene
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABLIM1 Gene
ABLIM1 (Actin Binding LIM Protein 1) is a Protein Coding gene. Among its related pathways are Netrin-1 signaling and Netrin Signaling. GO annotations related to this gene include actin binding. An important paralog of this gene is ABLIM3.
UniProtKB/Swiss-Prot for ABLIM1 Gene
May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.