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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ABLIM1 Gene

protein-coding GIFtS: 62
GCID: GC10M116190

actin binding LIM protein 1

(Previous symbols: LIMAB1, ABLIM)

Explore 4 diseases affiliated with
ABLIM1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Actin Binding LIM Protein 1¹ ²		LIMATIN²
LIMAB1¹ ² ³ ⁵		Actin-Binding Double-Zinc-Finger Protein²
ABLIM¹ ² ³		Actin-Binding LIM Protein 1²
Actin-Binding LIM Protein Family Member 1² ³		KIAA0059³
AbLIM-1¹		Limatin³
AbLIM¹		Actin-Binding Double Zinc Finger Protein³
Limatin³

External Ids:	HGNC: 78¹	Entrez Gene: 3983²	Ensembl: ENSG00000099204⁷	OMIM: 602330⁵	UniProtKB: O14639³

Export aliases for ABLIM1 gene to outside databases

Previous GC identifers: GC10M115109 GC10M115434 GC10M116322 GC10M115855 GC10M116180 GC10M109817

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABLIM1:

This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to

erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental

pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions.

The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets.

Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq, Jul

2008)

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639

Function: May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been

suggested to play a role in axon guidance

Gene Wiki entry for ABLIM1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ABLIM1 gene promoter:
AhR SRF SRF (504 AA) Lmo2 LCR-F1 C/EBPalpha YY1 Arnt AREB6 IRF-7A
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ABLIM1 promoter sequence

Search SABiosciences Chromatin IP Primers for ABLIM1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABLIM1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25 Ensembl cytogenetic band: 10q25.3 HGNC cytogenetic band: 10q25

ABLIM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABLIM1 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M116190: view genomic region (about GC identifiers)

Start:	116,190,869 bp from pter	End:	116,444,414 bp from pter
Size:	253,546 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639 (See protein sequence)

Recommended Name: Actin-binding LIM protein 1

Size: 778 amino acids; 87688 Da

Subunit: Binds F-actin. Interacts with ABRA

Subcellular location: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associated with the

cytoskeleton (By similarity)

Sequence caution: Sequence=BAA06681.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: A6NI16 A6NJ06 A8MXA9 Q15039 Q5JVV1 Q5JVV2 Q5T6N3 Q5T6N5 Q68CQ9 Q9BUP1

Alternative splicing: 5 isoforms: O14639-1 O14639-2 O14639-3 O14639-4 O14639-5

Explore the universe of human proteins at neXtProt for ABLIM1: NX_O14639

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O14639

ABLIM1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_001003407.1 NP_001003408.1 NP_002304.3 NP_006711.3

ENSEMBL proteins:

ENSP00000338190 ENSP00000358256 ENSP00000376682 ENSP00000376679 ENSP00000358261

ENSP00000358260 ENSP00000277895 ENSP00000358257 ENSP00000414154 ENSP00000400934

ENSP00000433629 ENSP00000358270

Reactome Protein details: O14639
Human Recombinant Protein Products:

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	Uscn Proteins for ABLIM1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0015629	actin cytoskeleton	IEA	--

ABLIM1 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for ABLIM1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ABLIM1 for domains About GeneDecksing

2 InterPro domains/families:

IPR001781 Znf_LIM

IPR003128 Villin_headpiece

Graphical View of Domain Structure for InterPro Entry O14639

ProtoNet protein and cluster: O14639

2 Blocks protein families:

IPB001781 Zn-binding protein

IPB003128 Villin headpiece

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639

Similarity: Contains 1 HP (headpiece) domain

Similarity: Contains 4 LIM zinc-binding domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639

Function: May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been

suggested to play a role in axon guidance

miRNA Products:		OriGene 3'-UTR Clone (see all 4): ABLIM1 Browse MicroRNA Expression Plasmids
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		8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate ABLIM1 (see all 29):
		hsa-miR-3128 hsa-miR-3678-3p hsa-miR-1321 hsa-miR-3200-5p hsa-miR-4251 hsa-miR-513a-5p hsa-miR-216b hsa-miR-449a

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABLIM1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--
GO:0005515	protein binding	IPI	16189514
GO:0008270	zinc ion binding	IEA	--

ABLIM1 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for ABLIM1:

Increased gamma-H2AX phosphory

Increased homologous recombina

Animal Models:
Mouse knock-out Ablim1^tm1Lex for ABLIM1
1 MGI mutant phenotype (inferred from 2 alleles) (MGI details for Ablim1):

normal

ABLIM1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Axon guidance

Axon guidance

1.00

Developmental Biology

0.69

Netrin-1 signaling

Netrin-1 signaling

1.00

DCC mediated attractive signaling

0.33

Netrin Signaling

Netrin Signaling

1.00

Axon guidance

Axon guidance

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ABLIM1

Netrin Signaling

4 Reactome Pathways for ABLIM1

	Developmental Biology
	Netrin-1 signaling
	DCC mediated attractive signaling
	Axon guidance

1 Kegg Pathway (Kegg details for ABLIM1):

Axon guidance

ABLIM1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ABLIM1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/33 Interacting proteins for ABLIM1 (O14639^{1, 2, 3} ENSP00000338190⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 33)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
KRT15	P19012²^,³, ENSP00000254043⁴	MINT-68218 I2D: score=5 STRING: ENSP00000254043
SFN	P31947²^,³	MINT-3974750 I2D: score=2
LDOC1	O95751¹^,²^,³, ENSP00000359557⁴	EBI-487024,EBI-740738 MINT-67267 I2D: score=6 STRING: ENSP00000359557
GOLGA2	Q08379²^,³, ENSP00000416097⁴	MINT-66414 I2D: score=5 STRING: ENSP00000416097
BEGAIN	Q9BUH8²^,³, ENSP00000347301⁴	MINT-66438 I2D: score=5 STRING: ENSP00000347301

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007010	cytoskeleton organization	IEA	--
GO:0007411	axon guidance	TAS	--
GO:0007601	visual perception	TAS	9245787
GO:0009887	organ morphogenesis	TAS	9245787
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IEA	--

ABLIM1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ABLIM1
Search CenterWatch for drugs/clinical trials and news about ABLIM1 / ABLM1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ABLIM1 gene (4 alternative transcripts):

NM_001003407.1 NM_001003408.1 NM_002313.5 NM_006720.3

Unigene Clusters for ABLIM1:

Actin binding LIM protein 1

Hs.438236 [show with all ESTs], Hs.538331

Unigene Representative Sequences: NM_001003408, AK054890

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000336585(uc021pyw.1 uc021pyx.1) ENST00000369252(uc021pza.1)

ENST00000392955 ENST00000392952(uc021pyu.1) ENST00000369257 ENST00000369256(uc021pze.1)

ENST00000277895(uc021pzd.1) ENST00000369253 ENST00000485570 ENST00000440467

ENST00000428430 ENST00000466400 ENST00000481974 ENST00000477638(uc001lbz.1)

ENST00000533213(uc021pyy.1 uc021pyz.1 uc021pzf.1) ENST00000369266(uc021pyv.1 uc021pzb.1 uc021pzc.1)

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		8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate ABLIM1 (see all 29):
		hsa-miR-3128 hsa-miR-3678-3p hsa-miR-1321 hsa-miR-3200-5p hsa-miR-4251 hsa-miR-513a-5p hsa-miR-216b hsa-miR-449a

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Additional cDNA sequence: AK054890.1

24/28 DOTS entries (see all 28):

DT.95113279 DT.95206861 DT.95228019 DT.101984191 DT.100798559 DT.95228045 DT.100798557 DT.121288101

DT.121288169 DT.95228040 DT.100798556 DT.95299536 DT.100798561 DT.121288094 DT.40116746 DT.95147880

DT.40276377 DT.95228020 DT.95320564 DT.99939110 DT.100008480 DT.91976084 DT.121288229 DT.121288243

1 AceView cDNA sequence:

AK054890

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ABLIM1 (see all 9) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	·	4c	^	5	^	6	^	7a	·	7b	^	8a	·	8b	·	8c	·	8d	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19a	·
SP1:					-				-														-		-		-		-																						-
SP2:					-				-														-		-		-		-						-																-
SP3:																													-																-						-
SP4:																													-						-		-								-						-
SP5:																													-						-

ExUns:	19b	^	20	^	21	^	22	^	23	^	24	^	25
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ABLIM1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ABLIM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTGTGTGTA

About this image

ABLIM1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Umbilical Cord

Umbilical Veins

Umbilical Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 7 LifeMap Cells

Name

Category

PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)

Endothelium

PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)

Lateral Plate Mesoderm, Neural Crest

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

PureStem™ progenitor T36 (Embryonic Progenitor Cell)

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Blimp1- mVenus and stella-ECFP genetically modified stem cells (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

See ABLIM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABLIM1

SOURCE GeneReport for Unigene clusters: Hs.438236 Hs.538331

UniProtKB/Swiss-Prot: ABLM1_HUMAN, O14639

Tissue specificity: Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner

segment and in the outer plexiform layers

SABiosciences Custom PCR Arrays for ABLIM1

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABLIM1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABLIM1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ABLIM1 gene from 6/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ABLIM1¹	actin binding LIM protein 1	84.3(n) 93.04(a)		423911 NM_001159363.1 NP_001152835.1
lizard (Anolis carolinensis)	Reptilia	ABLIM1⁶	--	79(a)	1 ↔ 1	GL343206.1(3978576-4152149)
African clawed frog (Xenopus laevis)	Amphibia	Xl.28513²	Xenopus laevis transcribed sequence with weak similarity more	78.15(n)		BJ074832.1
zebrafish (Danio rerio)	Actinopterygii	ablim1a¹	actin binding LIM protein 1a	73.24(n) 76.89(a)		100003558 NM_001114316.1 NP_001107788.1
fruit fly (Drosophila melanogaster)	Insecta	Unc-115a¹	CG31352-PA	50.94(n) 44.97(a)		261629 NM_001170103.1 NP_001163574.1
worm (Caenorhabditis elegans)	Secernentea	unc-115¹	Protein UNC-115	47.75(n) 39.19(a)		181227 NM_001029371.2 NP_001024542.1

ENSEMBL Gene Tree for ABLIM1 (if available)
TreeFam Gene Tree for ABLIM1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ABLIM1 gene

ABLIM3² LIMS1² LIMS3L² FHL5² LDB3² LPXN² ABLIM2² PDLIM5²

ENSG00000257207² LIMS2² FHL2² PDLIM7² EPB49² FHL3² FHL1² TGFB1I1²

LIMS3² PXN²

18/19 SIMAP similar genes for ABLIM1 using alignment to 9 protein entries: ABLM1_HUMAN (see all proteins) (see all similar genes):

ABLIM3 LHx4 CRIP1 LHX2 ABLIM2 LHX3

LIMS1 CRIP2 LHX8 EPB49 LMO1 AJUBA

ISL2 LHX4 LMO3 LIMK2 LMO4 LIMS2

ABLIM1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs7097492^1,2	C,	--	109817484(+)	`TGTATT/CCCCAC`	4	--	ds500¹		2		WA	120
rs76669575^1,2	C,F,	--	109817840(+)	`CACAGC/TTTTTC`	4	--	ut3¹		1		WA	118
rs74160407^1,2	C,	--	109818737(+)	`AGTACA/CGATTA`	4	--	ut3¹		2		WA	120
rs41293056^1,2		--	109819123(+)	`CTAGAC/TGTCTC`	4	--	ut3¹		1		NA	120
rs77656682^1,2	F,	--	109819130(+)	`TCTCCG/AAGTTA`	4	--	ut3¹		1		EA	120
rs55748348^1,2		--	109819239(+)	`CAGAAC/TTGGGT`	4	--	ut3¹		0	--	--	--	--
rs76140744^1,2		--	109819536(+)	`TCCTAT/CCATCA`	4	--	ut3¹		1		WA	118
rs7906167^1,2	C,F,A,H,	--	109819573(+)	`NNNNAT/CGCACT`	4	--	ut3¹ ese³		14		NS EA NA WA	1490
rs115859423^1,2	C,F,	--	109820169(+)	`NNNNCT/GTTATC`	4	--	ut3¹		1		WA	118
rs115533700^1,2	C,F,	--	109820304(+)	`AAGAGG/AAATTT`	4	--	ut3¹		1		WA	118

HapMap Linkage Disequilibrium report for ABLIM1 (116190869 - 116440869 bp, first 250kb of ABLIM1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ABLIM1
2 CNVs: 39062 65790

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ABLIM1 for disorders           About GeneDecksing

OMIM gene information: 602330    OMIM disorders: --

4 diseases for ABLIM1:    About MalaCards

corneal neovascularization intrahepatic cholangiocarcinoma cholangiocarcinoma alzheimer's disease

1 Novoseek disease relationship for ABLIM1 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
cancer	0	3	16328021 (1), 9417918 (1)

Human Genome Epidemiology (HuGE) Navigator: ABLIM1 (3 documents)

Export disorders for ABLIM1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ABLIM1 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with ABLIM1)

Utopia: connect your pdf to the dynamic
world of online information

Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein. (PubMed id 9245787)^{1, 2, 3, 9} Roof D.J.... Li T. (1997)
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)^{1, 2} Rush J.... Comb M.J. (2005)
Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)^{1, 2} Brill L.M....Peters E.C. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{1, 2} Nakajima D.... Nagase T. (2002)
Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)^{1, 2} Nomura N....Tabata S. (1994)
Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. (PubMed id 9417918)^{1, 9} Kim A.C....Chishti A.H. (1997)
Polymorphisms in ABLIM1 are associated with personalit y traits and alcohol dependence. (PubMed id 21547531)¹ Wang K.S....Liu Y. (2012)
A genome-wide search for loci interacting with known p rostate cancer risk-associated genetic variants. (PubMed id 22219177)¹ Tao S....Sun J. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 3983	HGNC: 78	AceView: ABLIM1.1	Ensembl:ENSG00000099204	euGenes: HUgn3983
ECgene: ABLIM1	Kegg: 3983	H-InvDB: ABLIM1

(According to HUGE)
About This Section

HUGE: KIAA0059

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ABLIM1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ABLIM1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ABLIM1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ABLIM1 gene:
Search GeneIP for patents involving ABLIM1

GeneCards and IP:
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actin binding LIM protein 1

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