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Aliases for ABI3BP Gene

Aliases for ABI3BP Gene

  • ABI Family, Member 3 (NESH) Binding Protein 2 3
  • TARSH 3 4 6
  • ABI Gene Family Member 3-Binding Protein 3 4
  • Nesh-Binding Protein 3 4
  • Target Of Nesh-SH3 2 3
  • NESHBP 3 4
  • ABI Gene Family, Member 3 (NESH) Binding Protein 3

External Ids for ABI3BP Gene

Previous GeneCards Identifiers for ABI3BP Gene

  • GC03M101951
  • GC03M100468
  • GC03M097836

Summaries for ABI3BP Gene

GeneCards Summary for ABI3BP Gene

ABI3BP (ABI Family, Member 3 (NESH) Binding Protein) is a Protein Coding gene. GO annotations related to this gene include heparin binding and collagen binding. An important paralog of this gene is FNDC1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABI3BP Gene

Genomics for ABI3BP Gene

Regulatory Elements for ABI3BP Gene

Genomic Location for ABI3BP Gene

Start:
100,749,156 bp from pter
End:
100,993,515 bp from pter
Size:
244,360 bases
Orientation:
Minus strand

Genomic View for ABI3BP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABI3BP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABI3BP Gene

Proteins for ABI3BP Gene

  • Protein details for ABI3BP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z7G0-TARSH_HUMAN
    Recommended name:
    Target of Nesh-SH3
    Protein Accession:
    Q7Z7G0
    Secondary Accessions:
    • B3KSL4
    • Q6ZW20
    • Q6ZW22
    • Q9C082
    • Q9UFI6

    Protein attributes for ABI3BP Gene

    Size:
    1075 amino acids
    Molecular mass:
    118642 Da
    Quaternary structure:
    • Probably interacts with ABI3
    SequenceCaution:
    • Sequence=CAB56034.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ABI3BP Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABI3BP Gene

Proteomics data for ABI3BP Gene at MOPED

Post-translational modifications for ABI3BP Gene

  • Glycosylation at Asn44
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ABI3BP Gene

Domains for ABI3BP Gene

Gene Families for ABI3BP Gene

HGNC:
  • FN3 :Fibronectin type III domain containing

Protein Domains for ABI3BP Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ABI3BP Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z7G0

UniProtKB/Swiss-Prot:

TARSH_HUMAN :
  • Q7Z7G0
Domain:
  • Contains 2 fibronectin type-III domains.
genes like me logo Genes that share domains with ABI3BP: view

Function for ABI3BP Gene

Gene Ontology (GO) - Molecular Function for ABI3BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0005518 collagen binding IEA --
GO:0005539 glycosaminoglycan binding --
GO:0008201 heparin binding IEA --
genes like me logo Genes that share ontologies with ABI3BP: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ABI3BP Gene

Localization for ABI3BP Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABI3BP Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ABI3BP Gene COMPARTMENTS Subcellular localization image for ABI3BP gene
Compartment Confidence
extracellular 4
plasma membrane 3
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for ABI3BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005614 interstitial matrix IEA --
GO:0005615 extracellular space IDA 20551380
GO:0031012 colocalizes_with extracellular matrix IDA 20551380
genes like me logo Genes that share ontologies with ABI3BP: view

Pathways for ABI3BP Gene

SuperPathways for ABI3BP Gene

No Data Available

Gene Ontology (GO) - Biological Process for ABI3BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010811 positive regulation of cell-substrate adhesion IEA --
GO:0030198 extracellular matrix organization IEA --
genes like me logo Genes that share ontologies with ABI3BP: view

No data available for Pathways by source for ABI3BP Gene

Transcripts for ABI3BP Gene

Unigene Clusters for ABI3BP Gene

ABI family, member 3 (NESH) binding protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ABI3BP Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
SP1: - -
SP2: -
SP3:
SP4:
SP5:

ExUns: 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32a · 32b ^ 33 ^ 34 ^ 35 ^ 36 ^ 37a · 37b
SP1: -
SP2:
SP3:
SP4:
SP5:

Relevant External Links for ABI3BP Gene

GeneLoc Exon Structure for
ABI3BP
ECgene alternative splicing isoforms for
ABI3BP

Expression for ABI3BP Gene

mRNA expression in normal human tissues for ABI3BP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ABI3BP Gene

This gene is overexpressed in Artery - Tibial (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ABI3BP Gene

SOURCE GeneReport for Unigene cluster for ABI3BP Gene Hs.477015

mRNA Expression by UniProt/SwissProt for ABI3BP Gene

Q7Z7G0-TARSH_HUMAN
Tissue specificity: Expressed in brain, heart, lung, liver, pancreas kidney and placenta.
genes like me logo Genes that share expressions with ABI3BP: view

Orthologs for ABI3BP Gene

This gene was present in the common ancestor of chordates.

Orthologs for ABI3BP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ABI3BP 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ABI3BP 35
  • 87.53 (n)
  • 87.07 (a)
ABI3BP 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ABI3BP 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abi3bp 16
Abi3bp 36
  • 68 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ABI3BP 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ABI3BP 36
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves ABI3BP 35
  • 63.37 (n)
  • 56.75 (a)
ABI3BP 36
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ABI3BP 36
  • 52 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii -- 35
abi3bp 36
  • 43 (a)
OneToMany
ABI3BP (1 of 2) 36
  • 32 (a)
OneToMany
Species with no ortholog for ABI3BP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ABI3BP Gene

ENSEMBL:
Gene Tree for ABI3BP (if available)
TreeFam:
Gene Tree for ABI3BP (if available)

Paralogs for ABI3BP Gene

Paralogs for ABI3BP Gene

genes like me logo Genes that share paralogs with ABI3BP: view

Variants for ABI3BP Gene

Sequence variations from dbSNP and Humsavar for ABI3BP Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs16334 -- 100,749,563(-) TAACT(-/AACT)GTTTA utr-variant-3-prime
rs17354 -- 100,802,011(+) TGGCA(A/G)TATTT intron-variant
rs182934 -- 100,755,908(+) AGATA(G/T)ATATT intron-variant
rs186924 -- 100,756,142(+) catgt(A/G)aaccc intron-variant
rs186957 -- 100,768,797(+) TAAAT(C/G)TGTGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ABI3BP Gene

Variant ID Type Subtype PubMed ID
dgv182e55 CNV Gain 17911159
dgv183e55 CNV Gain 17911159
esv5408 CNV Deletion 18987735
nsv822202 CNV Loss 20364138
dgv819n67 CNV Loss 20364138
esv2659333 CNV Deletion 23128226
esv2725700 CNV Deletion 23290073
esv21526 CNV Loss 19812545
nsv877221 CNV Gain 21882294
nsv514163 CNV Loss 21397061
nsv3922 CNV Loss 18451855
dgv1480e1 CNV Complex 17122850
esv2534604 CNV Deletion 19546169
nsv10294 CNV Loss 18304495
esv2308387 CNV Deletion 18987734
esv2668933 CNV Deletion 23128226
esv28693 CNV Loss 19812545
esv2422136 CNV Deletion 20811451
nsv441834 CNV CNV 18776908
nsv525082 CNV Loss 19592680

Relevant External Links for ABI3BP Gene

HapMap Linkage Disequilibrium report
ABI3BP
Human Gene Mutation Database (HGMD)
ABI3BP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABI3BP Gene

Disorders for ABI3BP Gene

Relevant External Links for ABI3BP

Genetic Association Database (GAD)
ABI3BP
Human Genome Epidemiology (HuGE) Navigator
ABI3BP
genes like me logo Genes that share disorders with ABI3BP: view

No data available for UniProtKB/Swiss-Prot for ABI3BP Gene

Publications for ABI3BP Gene

  1. Cloning and sequencing of a novel human gene that encodes a putative target protein of Nesh-SH3. (PMID: 11501947) Matsuda S. … Hamaguchi M. (J. Hum. Genet. 2001) 2 3 4
  2. Cancer-associated loss of TARSH gene expression in human primary lung cancer. (PMID: 16205947) Terauchi K. … Fushiki S. (J. Cancer Res. Clin. Oncol. 2006) 3 23
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Genome-wide association study of suicide attempts in mood disorder patients. (PMID: 21041247) Perlis R.H. … Smoller J.W. (Am J Psychiatry 2010) 3 48

Products for ABI3BP Gene

Sources for ABI3BP Gene

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