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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ABI3 Gene

protein-coding   GIFtS: 56
GCID: GC17P047287

ABI Family, Member 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ABI Family, Member 31 2
NESH2 3 5
New Molecule Including SH32 3
SSH3BP32
ABI Gene Family Member 32
Nesh3

External Ids:    HGNC: 298591   Entrez Gene: 512252   Ensembl: ENSG000001087987   OMIM: 6063635   UniProtKB: Q9P2A43   

Export aliases for ABI3 gene to outside databases

Previous GC identifers: GC17P047763 GC17P044642 GC17P042653


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABI3 Gene:
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a
homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE
complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as
well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative
splicing results in multiple transcript variants. (provided by RefSeq, Sep 2013)

GeneCards Summary for ABI3 Gene: 
ABI3 (ABI family, member 3) is a protein-coding gene. Diseases associated with ABI3 include chronic lymphocytic leukemia, and acute myeloid leukemia. GO annotations related to this gene include protein binding. An important paralog of this gene is ABI1.

UniProtKB/Swiss-Prot: ABI3_HUMAN, Q9P2A4
Function: May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility

Gene Wiki entry for ABI3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ABI3 gene promoter:
         GATA-3   CBF-C   GATA-2   Ik-2   CBF-A   CBF-B   CP1C   CP1A   LyF-1   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABI3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ABI3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABI3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.3

ABI3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABI3 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P047287:  view genomic region     (about GC identifiers)

Start:
47,287,589 bp from pter      End:
47,300,587 bp from pter
Size:
12,999 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ABI3_HUMAN, Q9P2A4 (See protein sequence)
Recommended Name: ABI gene family member 3  
Size: 366 amino acids; 39035 Da
Subunit: May interact with PAK1 and PAK2. Probably interacts with TARSH
Subcellular location: Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells
Secondary accessions: C9IZN8 Q9H0P6
Alternative splicing: 2 isoforms:  Q9P2A4-1   Q9P2A4-2   

Explore the universe of human proteins at neXtProt for ABI3: NX_Q9P2A4

Explore proteomics data for ABI3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P2A4

  • ABI3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ABI3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001128658.1  NP_057512.1  

    ENSEMBL proteins: 
     ENSP00000225941   ENSP00000406651   ENSP00000460776   ENSP00000459171  

    Human Recombinant Protein Products for ABI3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein for ABI3
    OriGene Protein Over-expression Lysate for ABI3
    OriGene MassSpec for ABI3 
    OriGene Custom Protein Services for ABI3
    GenScript Custom Purified and Recombinant Proteins Services for ABI3
    Novus Biologicals ABI3 Proteins
    Novus Biologicals ABI3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for ABI3
    Cloud-Clone Corp. Proteins for ABI3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA17101133
    GO:0005737cytoplasm NAS11956071
    GO:0030027lamellipodium IDA17101133

    ABI3 for ontologies           About GeneDecksing



    ABI3 Antibody Products: 
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    Assay Products for ABI3: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for ABI3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ABI3 
    Cloud-Clone Corp. CLIAs for ABI3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR012849 Abl-interactor_HHR_dom
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry Q9P2A4

    ProtoNet protein and cluster: Q9P2A4

    2 Blocks protein domains:
    IPB001452 SH3 domain signature
    IPB012849 Abl-interactor HHR


    UniProtKB/Swiss-Prot: ABI3_HUMAN, Q9P2A4
    Similarity: Belongs to the ABI family
    Similarity: Contains 1 SH3 domain


    ABI3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABI3_HUMAN, Q9P2A4
    Function: May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
         
    ABI3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ABI3:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ABI3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ABI3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ABI3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ABI3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABI3
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate ABI3:
    hsa-miR-4283 hsa-miR-1184 hsa-miR-4272
    SwitchGear 3'UTR luciferase reporter plasmidABI3 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: ABI3 (NM_015429)
    Sino Biological Human cDNA Clone for ABI3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABI3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABI3
    Sirion Biotech Customized lentivirus for stable overexpression of ABI3 
                         Customized lentivirus expression plasmids for stable overexpression of ABI3 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABI3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABI3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/32 Interacting proteins for ABI3 (Q9P2A41, 2, 3 ENSP000002259414) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DTNBP1Q96EV82, 3, ENSP000003416804MINT-66229 I2D: score=5 STRING: ENSP00000341680
    HOMER1Q86YM72, 3, ENSP000003343824MINT-66923 I2D: score=5 STRING: ENSP00000334382
    KRT15P190122, 3, ENSP000002540434MINT-67148 I2D: score=5 STRING: ENSP00000254043
    TMEM147Q9BVK82, 3, ENSP000002222844MINT-66733 I2D: score=5 STRING: ENSP00000222284
    EIF3HO153721, 3, ENSP000002766824EBI-742038,EBI-709735 I2D: score=4 STRING: ENSP00000276682
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006928cellular component movement NAS11956071
    GO:0018108NOT peptidyl-tyrosine phosphorylation IDA17101133
    GO:0030334regulation of cell migration IDA11956071

    ABI3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ABI3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ABI3

    1 Novoseek inferred chemical compound relationship for ABI3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    abscisic acid 77.6 25 9161030 (8), 7827492 (3), 11115891 (2), 11737778 (2)

    Search CenterWatch for drugs/clinical trials and news about ABI3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ABI3 gene (2 alternative transcripts): 
    NM_001135186.1  NM_016428.2  

    Unigene Cluster for ABI3:

    ABI family, member 3
    Hs.130719  [show with all ESTs]
    Unigene Representative Sequence: AB037886
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000225941(uc002ioq.1 uc002iop.1) ENST00000419580 ENST00000573347
    ENST00000571035
    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate ABI3:
    hsa-miR-4283 hsa-miR-1184 hsa-miR-4272
    SwitchGear 3'UTR luciferase reporter plasmidABI3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABI3
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    GenScript: all cDNA clones in your preferred vector: ABI3 (NM_015429)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABI3
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                         Customized lentivirus expression plasmids for stable overexpression of ABI3 
    Primer
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    OriGene qPCR primer pairs and template standards for ABI3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABI3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABI3

    Additional mRNA sequence: 

    AB037886.1 AL136709.1 BC007780.2 

    4 DOTS entries:

    DT.108938  DT.95184620  DT.97841061  DT.97841062 

    24/71 AceView cDNA sequences (see all 71):

    AI301619 BF437660 AW204075 AW136767 BI835429 BC007780 BI907503 NM_016428 
    BI906278 AB037886 BG744250 CR621565 BI768790 CR608488 AA721188 BI833256 
    BI839121 AA622957 BI906791 BI772446 BI771802 BM918896 BG398401 CA418390 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ABI3    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8
    SP1:                                                              -           -         
    SP2:                    -                                                               
    SP3:                                                                                    


    ECgene alternative splicing isoforms for ABI3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ABI3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGGACAGGG
    ABI3 Expression
    About this image


    See ABI3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ABI3

    SOURCE GeneReport for Unigene cluster: Hs.130719

    UniProtKB/Swiss-Prot: ABI3_HUMAN, Q9P2A4
    Tissue specificity: Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and
    skeletal muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABI3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ABI3 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Abi31 , 5 ABI gene family, member 31, 5 83.29(n)1
    86.43(a)1
      11 (59.01 cM)5
    666101  NM_025659.41  NP_079935.11 
     958300745 
    chicken
    (Gallus gallus)
    Aves ABI31 ABI family, member 3 66.1(n)
    63.1(a)
      419988  XM_418110.3  XP_418110.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    61(a)
    45(a)
    1 ↔ many
    1 ↔ many
    AAWZ02040951(519-2748)
    6(76199630-76217666)
    zebrafish
    (Danio rerio)
    Actinopterygii ABI3 (1 of 2)6
    ABI3 (2 of 2)6
    ABI family, member 3
    31(a)
    23(a)
    1 ↔ many
    1 ↔ many
    3(33530060-33551944)
    12(6281077-6293478)
    fruit fly
    (Drosophila melanogaster)
    Insecta Abi6
    Abelson interacting protein
    25(a)
    1 → many
    3R(9944984-9948142)
    worm
    (Caenorhabditis elegans)
    Secernentea abi-16
    Protein ABI-1
    26(a)
    1 → many
    III(5690107-5692740)


    ENSEMBL Gene Tree for ABI3 (if available)
    TreeFam Gene Tree for ABI3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ABI3 gene
    ABI12  ABI22  
    6 SIMAP similar genes for ABI3 using alignment to 4 protein entries:     ABI3_HUMAN (see all proteins):
    ABI-2    SH3GL1    SH3GL2    ARHGEF7    SH3RF3    ABI1

    ABI3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ABI3
    PGOHUM00000250839


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/279 SNPs in ABI3 are shown (see all 279)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0609934
    ----see VAR_0609932 F S mis40--------
    VAR_0602434
    ----see VAR_0602432 S F mis40--------
    rs21076331,2
    H--42656346(-) cttcaG/Tatgag 2 -- int14Minor allele frequency- T:0.00NS EA 420
    rs1503657171,2
    --42656352(+) TGAAGC/TCCGGT 2 -- int10--------
    rs10095711,2
    C,F,A,H--42656396(+) agctgA/Gggttt 2 -- int113Minor allele frequency- G:0.09NA EA NS WA 1018
    rs10095721,2
    C,F,A,H--42656437(+) cctagC/Ttagtg 2 -- int123Minor allele frequency- T:0.12NS EA NA WA 2770
    rs1112908381,2
    C,F--42656441(+) GCTAGT/CGTCAG 2 -- int12Minor allele frequency- C:0.07CSA WA 120
    rs1815198801,2
    --42656443(+) TAGTGG/TCAGAG 2 -- int10--------
    rs800408441,2
    F--42656462(+) CAAACG/ACAGAA 2 -- int11Minor allele frequency- A:0.04WA 118
    rs1866511021,2
    C--42656548(+) GTTGAA/GTGACC 2 -- int10--------

    HapMap Linkage Disequilibrium report for ABI3 (47287589 - 47300587 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ABI3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv2074CNV Insertion18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ABI3
    DNA2.0 Custom Variant and Variant Library Synthesis for ABI3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606363    OMIM disorders: --

    4 diseases for ABI3:    About MalaCards
    chronic lymphocytic leukemia    acute myeloid leukemia    myeloid leukemia    leukemia


    ABI3 for disorders           About GeneDecksing


    Export disorders for ABI3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ABI3 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with ABI3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. (PubMed id 11956071)1, 2, 3 Ichigotani Y....Matsuda S. (2002)
    2. Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein. (PubMed id 10978530)1, 2, 3 Miyazaki K.... Hamaguchi M. (2000)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    5. Cloning and sequencing of a novel human gene that encodes a putative target protein of Nesh-SH3. (PubMed id 11501947)1, 2 Matsuda S.... Hamaguchi M. (2001)
    6. Loci associated with N-glycosylation of human immunogl obulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (2013)
    7. Identification of 23 new prostate cancer susceptibilit y loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (2013)
    8. ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence. (PubMed id 21223585)1 Latini F.R....Cerutti J.M. (2011)
    9. An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
    10. NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation. (PubMed id 17101133)1 Hirao N....Tani K. (2006)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51225 HGNC: 29859 AceView: ABI3 Ensembl:ENSG00000108798 euGenes: HUgn51225
    ECgene: ABI3 H-InvDB: ABI3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for ABI3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ABI3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ABI3 gene:
    Search GeneIP for patents involving ABI3

    GeneCards and IP:
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