Aliases for ABHD6 Gene
External Ids for ABHD6 Gene
Previous GeneCards Identifiers for ABHD6 Gene
GeneCards Summary for ABHD6 Gene
ABHD6 (Abhydrolase Domain Containing 6) is a Protein Coding gene. Among its related pathways are Circadian entrainment and triacylglycerol degradation. GO annotations related to this gene include acylglycerol lipase activity.
UniProtKB/Swiss-Prot for ABHD6 Gene
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. May also have a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity).
ABHD6 encodes a serine hydrolase enzyme known as alpha/beta-hydrolase domain 6. This enzyme catalyzes the hydrolysis of 2-arachidonylglycerol.