Aliases for ABHD3 Gene
External Ids for ABHD3 Gene
Previous GeneCards Identifiers for ABHD3 Gene
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABHD3 Gene
ABHD3 (Abhydrolase Domain Containing 3) is a Protein Coding gene. Among its related pathways are Glycerophospholipid biosynthesis and Metabolism. GO annotations related to this gene include carboxylic ester hydrolase activity and phosphatidylcholine 1-acylhydrolase activity. An important paralog of this gene is ABHD1.
UniProtKB/Swiss-Prot for ABHD3 Gene
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.