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Aliases for ABHD18 Gene

Aliases for ABHD18 Gene

  • Abhydrolase Domain Containing 18 2 3 5
  • Alpha/Beta Hydrolase Domain-Containing Protein 18 3 4
  • Abhydrolase Domain-Containing Protein 18 3 4
  • C4orf29 3 4
  • Chromosome 4 Open Reading Frame 29 2
  • Uncharacterized Protein C4orf29 3

External Ids for ABHD18 Gene

Previous HGNC Symbols for ABHD18 Gene

  • C4orf29

Summaries for ABHD18 Gene

GeneCards Summary for ABHD18 Gene

ABHD18 (Abhydrolase Domain Containing 18) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD18 Gene

Genomics for ABHD18 Gene

Regulatory Elements for ABHD18 Gene

Promoters for ABHD18 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ABHD18 on UCSC Golden Path with GeneCards custom track

Genomic Location for ABHD18 Gene

Chromosome:
4
Start:
127,965,261 bp from pter
End:
128,039,711 bp from pter
Size:
74,451 bases
Orientation:
Plus strand

Genomic View for ABHD18 Gene

Genes around ABHD18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABHD18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABHD18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD18 Gene

Proteins for ABHD18 Gene

  • Protein details for ABHD18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0P651-ABD18_HUMAN
    Recommended name:
    Protein ABHD18
    Protein Accession:
    Q0P651
    Secondary Accessions:
    • A1A4W8
    • A1A4W9
    • Q9H7A7

    Protein attributes for ABHD18 Gene

    Size:
    414 amino acids
    Molecular mass:
    46954 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ABHD18 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABHD18 Gene

Proteomics data for ABHD18 Gene at MOPED

Post-translational modifications for ABHD18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ABHD18 Gene

Domains & Families for ABHD18 Gene

Protein Domains for ABHD18 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q0P651

UniProtKB/Swiss-Prot:

ABD18_HUMAN :
  • Belongs to the AB hydrolase superfamily.
Family:
  • Belongs to the AB hydrolase superfamily.
genes like me logo Genes that share domains with ABHD18: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for ABHD18 Gene

Function for ABHD18 Gene

Phenotypes for ABHD18 Gene

genes like me logo Genes that share phenotypes with ABHD18: view

Animal Model Products

miRNA for ABHD18 Gene

miRTarBase miRNAs that target ABHD18

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ABHD18 Gene

Localization for ABHD18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABHD18 Gene

Secreted.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ABHD18 Gene

Pathways & Interactions for ABHD18 Gene

SuperPathways for ABHD18 Gene

No Data Available

Interacting Proteins for ABHD18 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000381937%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: Q0P651-ABD18_HUMAN ENSP00000381937 for ABHD18 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for ABHD18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ABHD18 Gene

Drugs & Compounds for ABHD18 Gene

No Compound Related Data Available

Transcripts for ABHD18 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD18 Gene

No ASD Table

Relevant External Links for ABHD18 Gene

GeneLoc Exon Structure for
ABHD18
ECgene alternative splicing isoforms for
ABHD18

Expression for ABHD18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expression patterns with ABHD18: view

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ABHD18 Gene

Orthologs for ABHD18 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABHD18 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia C19H4orf29 35
  • 93.24 (n)
  • 94.44 (a)
C4orf29 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 3110057O12Rik 35
  • 88.81 (n)
  • 90.58 (a)
Abhd18 16
3110057O12Rik 36
  • 81 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C4H4orf29 35
  • 99.68 (n)
  • 99.28 (a)
C4orf29 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC499602 35
  • 88.33 (n)
  • 91.3 (a)
cow
(Bos Taurus)
Mammalia MGC165715 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C4orf29 36
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C4orf29 36
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves C4H4ORF29 35
  • 75.65 (n)
  • 76.46 (a)
C4H4ORF29 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C4orf29 36
  • 71 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC68853 35
zebrafish
(Danio rerio)
Actinopterygii wufk51f04 35
zgc:110741 35
  • 65.07 (n)
  • 72.73 (a)
C14H4orf29 36
  • 62 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9375 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003371 35
  • 57.68 (n)
  • 62.42 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32112 35
  • 53.28 (n)
  • 51.58 (a)
CG32112 36
  • 40 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C54G4.7 35
  • 48.26 (n)
  • 39.83 (a)
C54G4.7 36
  • 33 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G12150 35
  • 44.48 (n)
  • 33.14 (a)
rice
(Oryza sativa)
Liliopsida Os02g0195000 35
  • 44.78 (n)
  • 37.61 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
OneToOne
Species with no ortholog for ABHD18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ABHD18 Gene

ENSEMBL:
Gene Tree for ABHD18 (if available)
TreeFam:
Gene Tree for ABHD18 (if available)

Paralogs for ABHD18 Gene

No data available for Paralogs for ABHD18 Gene

Variants for ABHD18 Gene

Sequence variations from dbSNP and Humsavar for ABHD18 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs413343 -- 128,027,824(-) ATGAT(C/T)TGCCT intron-variant
rs447300 -- 127,978,478(-) CTGTA(C/T)GCTTA intron-variant
rs450264 -- 128,027,434(-) agtga(A/G)actcc intron-variant
rs516804 -- 127,969,189(+) GTTTT(C/T)ttttt intron-variant
rs748630 -- 127,980,247(-) agaat(C/T)gaact intron-variant

Variation tolerance for ABHD18 Gene

Residual Variation Intolerance Score: 53.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.12; 75.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ABHD18 Gene

HapMap Linkage Disequilibrium report
ABHD18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ABHD18 Gene

Disorders for ABHD18 Gene

Relevant External Links for ABHD18

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ABHD18
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ABHD18

No disorders were found for ABHD18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABHD18 Gene

Publications for ABHD18 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3

Products for ABHD18 Gene

Sources for ABHD18 Gene

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