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Aliases for ABHD17C Gene

Aliases for ABHD17C Gene

  • Abhydrolase Domain Containing 17C 2 3
  • Family With Sequence Similarity 108, Member C1 2 3
  • FAM108C1 3 4
  • Abhydrolase Domain-Containing Protein FAM108C1 3
  • EC 3.-.-.- 4

External Ids for ABHD17C Gene

Previous HGNC Symbols for ABHD17C Gene

  • FAM108C1

Previous GeneCards Identifiers for ABHD17C Gene

  • GC15P080972

Summaries for ABHD17C Gene

GeneCards Summary for ABHD17C Gene

ABHD17C (Abhydrolase Domain Containing 17C) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity and serine-type peptidase activity. An important paralog of this gene is ABHD17B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD17C Gene

Genomics for ABHD17C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ABHD17C Gene

80,679,684 bp from pter
80,755,621 bp from pter
75,938 bases
Plus strand

Genomic View for ABHD17C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABHD17C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD17C Gene

No data available for Regulatory Elements for ABHD17C Gene

Proteins for ABHD17C Gene

  • Protein details for ABHD17C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Alpha/beta hydrolase domain-containing protein 17C
    Protein Accession:
    Secondary Accessions:
    • Q1RMD6
    • Q9NPM1

    Protein attributes for ABHD17C Gene

    329 amino acids
    Molecular mass:
    35831 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ABHD17C Gene


neXtProt entry for ABHD17C Gene

Proteomics data for ABHD17C Gene at MOPED

Post-translational modifications for ABHD17C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABHD17C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ABHD17C Gene

Domains & Families for ABHD17C Gene

Gene Families for ABHD17C Gene

Protein Domains for ABHD17C Gene


Suggested Antigen Peptide Sequences for ABHD17C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the AB hydrolase superfamily. ABHD17 family.
  • Belongs to the AB hydrolase superfamily. ABHD17 family.
genes like me logo Genes that share domains with ABHD17C: view

Function for ABHD17C Gene

Enzyme Numbers (IUBMB) for ABHD17C Gene

Gene Ontology (GO) - Molecular Function for ABHD17C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD17C: view

Phenotypes for ABHD17C Gene

GenomeRNAi human phenotypes for ABHD17C:
genes like me logo Genes that share phenotypes with ABHD17C: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD17C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Animal Models , Transcription Factor Targets and HOMER Transcription for ABHD17C Gene

Localization for ABHD17C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ABHD17C Gene

Pathways & Interactions for ABHD17C Gene

SuperPathways for ABHD17C Gene

No Data Available

Interacting Proteins for ABHD17C Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q6PCB6-AB17C_HUMAN ENSP00000258884 for ABHD17C Gene via I2D STRING

Gene Ontology (GO) - Biological Process for ABHD17C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD17C: view

No data available for Pathways by source and SIGNOR curated interactions for ABHD17C Gene

Drugs & Compounds for ABHD17C Gene

No Compound Related Data Available

Transcripts for ABHD17C Gene

Unigene Clusters for ABHD17C Gene

Abhydrolase domain containing 17C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD17C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD17C Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP2: - -
SP3: - - -
SP4: - - -

Relevant External Links for ABHD17C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ABHD17C Gene

mRNA expression in normal human tissues for ABHD17C Gene

mRNA differential expression in normal tissues according to GTEx for ABHD17C Gene

This gene is overexpressed in Colon - Transverse (x4.4) and Esophagus - Mucosa (x4.3).

Protein differential expression in normal tissues from HIPED for ABHD17C Gene

This gene is overexpressed in Bone (24.5), Peripheral blood mononuclear cells (13.0), and Heart (12.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ABHD17C Gene

SOURCE GeneReport for Unigene cluster for ABHD17C Gene Hs.459072

genes like me logo Genes that share expression patterns with ABHD17C: view

Protein tissue co-expression partners for ABHD17C Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ABHD17C Gene

Orthologs for ABHD17C Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABHD17C Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ABHD17C 35
  • 92.2 (n)
  • 94.83 (a)
ABHD17C 36
  • 97 (a)
(Mus musculus)
Mammalia Abhd17c 35
  • 90.52 (n)
  • 95.31 (a)
Fam108c 16
Abhd17c 36
  • 98 (a)
(Pan troglodytes)
Mammalia FAM108C1 35
  • 90.15 (n)
  • 90.25 (a)
ABHD17C 36
  • 89 (a)
(Rattus norvegicus)
Mammalia Abhd17c 35
  • 89.48 (n)
  • 95.31 (a)
(Canis familiaris)
Mammalia ABHD17C 36
  • 100 (a)
(Monodelphis domestica)
Mammalia ABHD17C 36
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia ABHD17C 36
  • 88 (a)
(Gallus gallus)
Aves ABHD17C 35
  • 85.31 (n)
  • 95.72 (a)
ABHD17C 36
  • 95 (a)
(Anolis carolinensis)
Reptilia ABHD17C 36
  • 95 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia abhd17c 35
  • 78.71 (n)
  • 90.97 (a)
Str.1269 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.6584 35
(Danio rerio)
Actinopterygii abhd17c 35
  • 79.93 (n)
  • 89.46 (a)
zgc55468 35
abhd17c 36
  • 89 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10703 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010402 35
  • 65.86 (n)
  • 76.12 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33096 35
  • 67.96 (n)
  • 69.96 (a)
CG33096 36
  • 70 (a)
(Caenorhabditis elegans)
Secernentea aho-3 35
  • 57.98 (n)
  • 63.03 (a)
Y41E3.18 36
  • 22 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 21 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G31020 35
  • 52.62 (n)
  • 49.61 (a)
(Oryza sativa)
Liliopsida Os02g0796600 35
  • 57.1 (n)
  • 51.39 (a)
(Triticum aestivum)
Liliopsida Ta.30013 35
(Zea mays)
Liliopsida Zm.1574 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8399 36
  • 73 (a)
Species with no ortholog for ABHD17C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for ABHD17C Gene

Gene Tree for ABHD17C (if available)
Gene Tree for ABHD17C (if available)

Paralogs for ABHD17C Gene

Paralogs for ABHD17C Gene

(2) SIMAP similar genes for ABHD17C Gene using alignment to 2 proteins: Pseudogenes for ABHD17C Gene

genes like me logo Genes that share paralogs with ABHD17C: view

Variants for ABHD17C Gene

Sequence variations from dbSNP and Humsavar for ABHD17C Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs923000 -- 80,707,660(-) aaccc(A/G/T)cggcc intron-variant
rs958091 -- 80,732,026(+) ACATT(A/T)AAAGT intron-variant
rs960170 -- 80,731,835(+) ATTTA(A/G)GAGGA intron-variant
rs967839 -- 80,727,564(-) CCTCT(A/G)GGAAA intron-variant
rs972480 -- 80,734,710(-) AAGAA(C/T)GTAAT intron-variant

Variation tolerance for ABHD17C Gene

Residual Variation Intolerance Score: 32.53% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.12; 2.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ABHD17C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ABHD17C Gene

Disorders for ABHD17C Gene

Relevant External Links for ABHD17C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ABHD17C: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABHD17C Gene

Publications for ABHD17C Gene

  1. Genome-wide association study of antibody response to smallpox vaccine. (PMID: 22542470) Ovsyannikova I.G. … Poland G.A. (Vaccine 2012) 67
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ABHD17C Gene

Sources for ABHD17C Gene

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