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Aliases for ABHD17A Gene

Aliases for ABHD17A Gene

  • Abhydrolase Domain Containing 17A 2 3
  • Family With Sequence Similarity 108, Member A1 2 3
  • C19orf27 3 4
  • FAM108A1 3 4
  • Alpha/Beta Hydrolase Domain-Containing Protein 17A 3
  • Abhydrolase Domain-Containing Protein FAM108A1 3
  • Chromosome 19 Open Reading Frame 27 2
  • EC 3.-.-.- 4

External Ids for ABHD17A Gene

Previous Symbols for ABHD17A Gene

  • C19orf27
  • FAM108A1

Summaries for ABHD17A Gene

GeneCards Summary for ABHD17A Gene

ABHD17A (Abhydrolase Domain Containing 17A) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD17B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD17A Gene

Genomics for ABHD17A Gene

Genomic Location for ABHD17A Gene

Start:
1,876,810 bp from pter
End:
1,885,547 bp from pter
Size:
8,738 bases
Orientation:
Minus strand

Genomic View for ABHD17A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABHD17A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD17A Gene

No data available for Regulatory Elements for ABHD17A Gene

Proteins for ABHD17A Gene

  • Protein details for ABHD17A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GS6-AB17A_HUMAN
    Recommended name:
    Alpha/beta hydrolase domain-containing protein 17A
    Protein Accession:
    Q96GS6
    Secondary Accessions:
    • A8K0G8
    • D6W5Z9
    • Q6PJU2
    • Q8WUH9
    • Q9BWL0
    • Q9H7Q9

    Protein attributes for ABHD17A Gene

    Size:
    310 amino acids
    Molecular mass:
    33990 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15709.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB84869.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC03419.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ABHD17A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABHD17A Gene

Proteomics data for ABHD17A Gene at MOPED

Post-translational modifications for ABHD17A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys92

Other Protein References for ABHD17A Gene

No data available for DME Specific Peptides for ABHD17A Gene

Domains for ABHD17A Gene

Gene Families for ABHD17A Gene

HGNC:
  • ABHD :Abhydrolase domain containing

Protein Domains for ABHD17A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

AB17A_HUMAN
Family:
  • Belongs to the AB hydrolase superfamily. ABHD17 family.:
    • Q96GS6
genes like me logo Genes that share domains with ABHD17A: view

Function for ABHD17A Gene

Enzyme Numbers (IUBMB) for ABHD17A Gene

Gene Ontology (GO) - Molecular Function for ABHD17A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23088713
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD17A: view

Phenotypes for ABHD17A Gene

GenomeRNAi human phenotypes for ABHD17A:
genes like me logo Genes that share phenotypes with ABHD17A: view

No data available for Molecular function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ABHD17A Gene

Localization for ABHD17A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABHD17A Gene

Secreted.

Gene Ontology (GO) - Cellular Components for ABHD17A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with ABHD17A: view

Pathways for ABHD17A Gene

SuperPathways for ABHD17A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ABHD17A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD17A: view

No data available for Pathways by source for ABHD17A Gene

Transcripts for ABHD17A Gene

Unigene Clusters for ABHD17A Gene

Abhydrolase domain containing 17A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD17A Gene

No ASD Table

Relevant External Links for ABHD17A Gene

GeneLoc Exon Structure for
ABHD17A
ECgene alternative splicing isoforms for
ABHD17A

Expression for ABHD17A Gene

mRNA expression in normal human tissues for ABHD17A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ABHD17A Gene

SOURCE GeneReport for Unigene cluster for ABHD17A Gene Hs.465542

genes like me logo Genes that share expressions with ABHD17A: view

Orthologs for ABHD17A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABHD17A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ABHD17A 37
  • 99 (a)
OneToOne
FAM108A1 36
  • 99.46 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia ABHD17A 36
  • 90.11 (n)
  • 93.55 (a)
ABHD17A 37
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ABHD17A 36
  • 91.18 (n)
  • 94.84 (a)
ABHD17A 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abhd17a 36
  • 87.85 (n)
  • 92.9 (a)
Abhd17a 37
  • 93 (a)
OneToOne
Fam108a 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 86 (a)
OneToMany
-- 37
  • 86 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ABHD17A 37
  • 91 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Abhd17a 36
  • 87.06 (n)
  • 93.2 (a)
chicken
(Gallus gallus)
Aves ABHD17A 37
  • 85 (a)
OneToOne
FAM108A1 36
  • 82.73 (n)
  • 87.13 (a)
lizard
(Anolis carolinensis)
Reptilia ABHD17A 37
  • 84 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia abhd17a 36
  • 69.19 (n)
  • 80.26 (a)
zebrafish
(Danio rerio)
Actinopterygii abhd17aa 37
  • 76 (a)
OneToMany
abhd17ab 36
  • 76.45 (n)
  • 84.52 (a)
abhd17ab 37
  • 81 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG33096 37
  • 68 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea aho-3 37
  • 51 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 37
  • 23 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G14390 36
  • 51 (n)
  • 51.15 (a)
rice
(Oryza sativa)
Liliopsida Os12g0286600 36
  • 54.09 (n)
  • 51.36 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8399 37
  • 70 (a)
OneToMany
Species with no ortholog for ABHD17A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ABHD17A Gene

ENSEMBL:
Gene Tree for ABHD17A (if available)
TreeFam:
Gene Tree for ABHD17A (if available)

Paralogs for ABHD17A Gene

Paralogs for ABHD17A Gene

Selected SIMAP similar genes for ABHD17A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ABHD17A: view

Variants for ABHD17A Gene

Sequence variations from dbSNP and Humsavar for ABHD17A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs893542 -- 1,881,920(+) CTGTC(A/G)GTCCC intron-variant, utr-variant-5-prime
rs893543 -- 1,881,921(+) TGTCA(A/G)TCCCC intron-variant, utr-variant-5-prime
rs1610107 -- 1,883,434(+) CCTAC(C/T)GGTGC intron-variant, upstream-variant-2KB
rs1610108 -- 1,883,655(+) CACCA(A/G)CCCGG intron-variant, upstream-variant-2KB
rs1866378 -- 1,887,365(+) ACACC(A/G)AAGGG upstream-variant-2KB

Relevant External Links for ABHD17A Gene

HapMap Linkage Disequilibrium report
ABHD17A

No data available for Structural Variations from Database of Genomic Variants (DGV) for ABHD17A Gene

Disorders for ABHD17A Gene

No disorders were found for ABHD17A Gene.

No data available for UniProtKB/Swiss-Prot for ABHD17A Gene

Publications for ABHD17A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for ABHD17A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ABHD17A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD17A
    • Block miRNA regulation of ABHD17A using miScript Target Protectors

    Sources for ABHD17A Gene

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