Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ABHD17A Gene

Aliases for ABHD17A Gene

  • Abhydrolase Domain Containing 17A 2 3 5
  • Alpha/Beta Hydrolase Domain-Containing Protein 17A 3 4
  • Family With Sequence Similarity 108, Member A1 2 3
  • Abhydrolase Domain-Containing Protein 17A 3 4
  • C19orf27 3 4
  • FAM108A1 3 4
  • Abhydrolase Domain-Containing Protein FAM108A1 3
  • Chromosome 19 Open Reading Frame 27 2
  • EC 3.-.-.- 4

External Ids for ABHD17A Gene

Previous HGNC Symbols for ABHD17A Gene

  • C19orf27
  • FAM108A1

Summaries for ABHD17A Gene

GeneCards Summary for ABHD17A Gene

ABHD17A (Abhydrolase Domain Containing 17A) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD17B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD17A Gene

Genomics for ABHD17A Gene

Regulatory Elements for ABHD17A Gene

Promoters for ABHD17A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ABHD17A on UCSC Golden Path with GeneCards custom track

Genomic Location for ABHD17A Gene

1,876,810 bp from pter
1,885,547 bp from pter
8,738 bases
Minus strand

Genomic View for ABHD17A Gene

Genes around ABHD17A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABHD17A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABHD17A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD17A Gene

Proteins for ABHD17A Gene

  • Protein details for ABHD17A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein ABHD17A
    Protein Accession:
    Secondary Accessions:
    • A8K0G8
    • D6W5Z9
    • Q6PJU2
    • Q8WUH9
    • Q9BWL0
    • Q9H7Q9

    Protein attributes for ABHD17A Gene

    310 amino acids
    Molecular mass:
    33990 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB15709.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB84869.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC03419.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ABHD17A Gene


neXtProt entry for ABHD17A Gene

Proteomics data for ABHD17A Gene at MOPED

Post-translational modifications for ABHD17A Gene

  • Ubiquitination at Lys 92
  • Modification sites at PhosphoSitePlus

Other Protein References for ABHD17A Gene

No data available for DME Specific Peptides for ABHD17A Gene

Domains & Families for ABHD17A Gene

Gene Families for ABHD17A Gene

Protein Domains for ABHD17A Gene


Suggested Antigen Peptide Sequences for ABHD17A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the AB hydrolase superfamily. ABHD17 family.
  • Belongs to the AB hydrolase superfamily. ABHD17 family.
genes like me logo Genes that share domains with ABHD17A: view

Function for ABHD17A Gene

Enzyme Numbers (IUBMB) for ABHD17A Gene

Gene Ontology (GO) - Molecular Function for ABHD17A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23088713
genes like me logo Genes that share ontologies with ABHD17A: view
genes like me logo Genes that share phenotypes with ABHD17A: view

Animal Models for ABHD17A Gene

MGI Knock Outs for ABHD17A:

Animal Model Products

No data available for Molecular function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for ABHD17A Gene

Localization for ABHD17A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABHD17A Gene


Gene Ontology (GO) - Cellular Components for ABHD17A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with ABHD17A: view

No data available for Subcellular locations from COMPARTMENTS for ABHD17A Gene

Pathways & Interactions for ABHD17A Gene

SuperPathways for ABHD17A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ABHD17A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD17A: view

No data available for Pathways by source and SIGNOR curated interactions for ABHD17A Gene

Drugs & Compounds for ABHD17A Gene

No Compound Related Data Available

Transcripts for ABHD17A Gene

Unigene Clusters for ABHD17A Gene

Abhydrolase domain containing 17A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD17A Gene

No ASD Table

Relevant External Links for ABHD17A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ABHD17A Gene

mRNA expression in normal human tissues for ABHD17A Gene

Protein differential expression in normal tissues from HIPED for ABHD17A Gene

This gene is overexpressed in Pancreas (14.4), Bone (12.9), Peripheral blood mononuclear cells (11.7), NK cells (8.7), Bone marrow mesenchymal stem cell (7.2), and CD8 Tcells (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ABHD17A Gene

SOURCE GeneReport for Unigene cluster for ABHD17A Gene Hs.465542

genes like me logo Genes that share expression patterns with ABHD17A: view

Protein tissue co-expression partners for ABHD17A Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABHD17A Gene

Orthologs for ABHD17A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABHD17A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ABHD17A 35
  • 90.11 (n)
  • 93.55 (a)
ABHD17A 36
  • 94 (a)
(Canis familiaris)
Mammalia ABHD17A 35
  • 91.18 (n)
  • 94.84 (a)
ABHD17A 36
  • 95 (a)
(Mus musculus)
Mammalia Abhd17a 35
  • 87.85 (n)
  • 92.9 (a)
Abhd17a 16
Abhd17a 36
  • 93 (a)
(Pan troglodytes)
Mammalia FAM108A1 35
  • 99.46 (n)
  • 100 (a)
ABHD17A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Abhd17a 35
  • 87.06 (n)
  • 93.2 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 86 (a)
-- 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia ABHD17A 36
  • 91 (a)
(Gallus gallus)
Aves FAM108A1 35
  • 82.73 (n)
  • 87.13 (a)
ABHD17A 36
  • 85 (a)
(Anolis carolinensis)
Reptilia ABHD17A 36
  • 84 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia abhd17a 35
  • 69.19 (n)
  • 80.26 (a)
(Danio rerio)
Actinopterygii abhd17ab 35
  • 76.45 (n)
  • 84.52 (a)
abhd17aa 36
  • 76 (a)
abhd17ab 36
  • 81 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33096 36
  • 68 (a)
(Caenorhabditis elegans)
Secernentea aho-3 36
  • 51 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 23 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G14390 35
  • 51 (n)
  • 51.15 (a)
(Oryza sativa)
Liliopsida Os12g0286600 35
  • 54.09 (n)
  • 51.36 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8399 36
  • 70 (a)
Species with no ortholog for ABHD17A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ABHD17A Gene

Gene Tree for ABHD17A (if available)
Gene Tree for ABHD17A (if available)

Paralogs for ABHD17A Gene

Paralogs for ABHD17A Gene

(2) SIMAP similar genes for ABHD17A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ABHD17A: view

Variants for ABHD17A Gene

Sequence variations from dbSNP and Humsavar for ABHD17A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs893542 -- 1,881,920(+) CTGTC(A/G)GTCCC intron-variant, utr-variant-5-prime
rs893543 -- 1,881,921(+) TGTCA(A/G)TCCCC intron-variant, utr-variant-5-prime
rs1610107 -- 1,883,434(+) CCTAC(C/T)GGTGC intron-variant, utr-variant-5-prime
rs1610108 -- 1,883,655(+) CACCA(A/G)CCCGG intron-variant, utr-variant-5-prime
rs1866378 -- 1,887,365(+) ACACC(A/G)AAGGG upstream-variant-2KB

Variation tolerance for ABHD17A Gene

Residual Variation Intolerance Score: 85.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.24; 40.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ABHD17A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ABHD17A Gene

Disorders for ABHD17A Gene

Relevant External Links for ABHD17A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ABHD17A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABHD17A Gene

Publications for ABHD17A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Protein interactions of the transcription factor Hoxa1. (PMID: 23088713) Lambert B. … Rezsohazy R. (BMC Dev. Biol. 2012) 3
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3

Products for ABHD17A Gene

Sources for ABHD17A Gene

Back to Top