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Aliases for ABHD16B Gene

Aliases for ABHD16B Gene

  • Abhydrolase Domain Containing 16B 2 3
  • C20orf135 3 4
  • Abhydrolase Domain-Containing Protein 16B 3
  • Chromosome 20 Open Reading Frame 135 2
  • DJ591C20.1 3
  • EC 3.-.-.- 4

External Ids for ABHD16B Gene

Previous Symbols for ABHD16B Gene

  • C20orf135

Summaries for ABHD16B Gene

GeneCards Summary for ABHD16B Gene

ABHD16B (Abhydrolase Domain Containing 16B) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD16A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD16B Gene

Genomics for ABHD16B Gene

Genomic Location for ABHD16B Gene

Start:
63,861,213 bp from pter
End:
63,863,306 bp from pter
Size:
2,094 bases
Orientation:
Plus strand

Genomic View for ABHD16B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABHD16B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD16B Gene

No data available for Regulatory Elements for ABHD16B Gene

Proteins for ABHD16B Gene

  • Protein details for ABHD16B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H3Z7-ABHGB_HUMAN
    Recommended name:
    Abhydrolase domain-containing protein 16B
    Protein Accession:
    Q9H3Z7
    Secondary Accessions:

    Protein attributes for ABHD16B Gene

    Size:
    469 amino acids
    Molecular mass:
    52555 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ABHD16B Gene

Proteomics data for ABHD16B Gene at MOPED

Post-translational modifications for ABHD16B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABHD16B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ABHD16B Gene

Domains for ABHD16B Gene

Gene Families for ABHD16B Gene

HGNC:
  • ABHD :Abhydrolase domain containing

Protein Domains for ABHD16B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ABHD16B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H3Z7

UniProtKB/Swiss-Prot:

ABHGB_HUMAN
Family:
  • Belongs to the AB hydrolase superfamily. ABHD16 family.:
    • Q9H3Z7
genes like me logo Genes that share domains with ABHD16B: view

Function for ABHD16B Gene

Enzyme Numbers (IUBMB) for ABHD16B Gene

Gene Ontology (GO) - Molecular Function for ABHD16B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD16B: view

Phenotypes for ABHD16B Gene

GenomeRNAi human phenotypes for ABHD16B:
genes like me logo Genes that share phenotypes with ABHD16B: view

No data available for Molecular function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ABHD16B Gene

Localization for ABHD16B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ABHD16B Gene

Pathways for ABHD16B Gene

SuperPathways for ABHD16B Gene

No Data Available

Interacting Proteins for ABHD16B Gene

Gene Ontology (GO) - Biological Process for ABHD16B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD16B: view

No data available for Pathways by source for ABHD16B Gene

Transcripts for ABHD16B Gene

mRNA/cDNA for ABHD16B Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(23) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ABHD16B Gene

Abhydrolase domain containing 16B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD16B Gene

No ASD Table

Relevant External Links for ABHD16B Gene

GeneLoc Exon Structure for
ABHD16B
ECgene alternative splicing isoforms for
ABHD16B

Expression for ABHD16B Gene

mRNA expression in normal human tissues for ABHD16B Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ABHD16B Gene

SOURCE GeneReport for Unigene cluster for ABHD16B Gene Hs.266774

genes like me logo Genes that share expressions with ABHD16B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABHD16B Gene

Orthologs for ABHD16B Gene

This gene was present in the common ancestor of animals.

Orthologs for ABHD16B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ABHD16B 35
  • 99.29 (n)
  • 98.72 (a)
ABHD16B 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ABHD16B 35
  • 86.99 (n)
  • 87.42 (a)
C13H20ORF135 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ABHD16B 35
  • 82.27 (n)
  • 75.53 (a)
ABHD16B 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abhd16b 35
  • 78.56 (n)
  • 85.47 (a)
Abhd16b 16
Abhd16b 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ABHD16B 36
  • 57 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Abhd16b 35
  • 78.82 (n)
  • 84.43 (a)
zebrafish
(Danio rerio)
Actinopterygii abhd16a 36
  • 41 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG1309 36
  • 29 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F37A4.1 36
  • 27 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 20 (a)
ManyToMany
CSA.9728 36
  • 35 (a)
ManyToMany
Species with no ortholog for ABHD16B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ABHD16B Gene

ENSEMBL:
Gene Tree for ABHD16B (if available)
TreeFam:
Gene Tree for ABHD16B (if available)

Paralogs for ABHD16B Gene

Paralogs for ABHD16B Gene

Selected SIMAP similar genes for ABHD16B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ABHD16B: view

Variants for ABHD16B Gene

Sequence variations from dbSNP and Humsavar for ABHD16B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs2236152 -- 63,862,674(-) TCCTG(C/G)GCCAA synonymous-codon, reference
rs2281534 - 63,861,569(-) GCACC(A/T)GCGCC missense, reference
rs2281535 -- 63,861,215(-) GTCTC(A/G)CTATG utr-variant-5-prime
rs2281536 -- 63,861,080(-) GGTGT(G/T)AGTCC upstream-variant-2KB
rs3215630 -- 63,862,541(-) GTGAC(-/A)GGGGG frameshift-variant, reference

Structural Variations from Database of Genomic Variants (DGV) for ABHD16B Gene

Variant ID Type Subtype PubMed ID
nsv913190 CNV Loss 21882294
dgv4644n71 CNV Loss 21882294
nsv428381 CNV Gain+Loss 18775914
nsv913250 CNV Loss 21882294
dgv4648n71 CNV Loss 21882294
nsv913267 CNV Loss 21882294
nsv828804 CNV Loss 20364138
nsv509784 CNV Insertion 20534489
nsv913268 CNV Loss 21882294
nsv913269 CNV Loss 21882294
nsv469773 CNV Gain 16826518

Relevant External Links for ABHD16B Gene

HapMap Linkage Disequilibrium report
ABHD16B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABHD16B Gene

Disorders for ABHD16B Gene

No disorders were found for ABHD16B Gene.

No data available for UniProtKB/Swiss-Prot for ABHD16B Gene

Publications for ABHD16B Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  4. Genome-scale RNAi screen for host factors required for HIV replication. (PMID: 18976975) Zhou H. … Espeseth A.S. (Cell Host Microbe 2008) 3
  5. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles R.A. … Easton D.F. (Nat. Genet. 2013) 3

Products for ABHD16B Gene

Sources for ABHD16B Gene

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