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Aliases for ABHD16B Gene

Aliases for ABHD16B Gene

  • Abhydrolase Domain Containing 16B 2 3 5
  • Alpha/Beta Hydrolase Domain-Containing Protein 16B 3 4
  • Abhydrolase Domain-Containing Protein 16B 3 4
  • C20orf135 3 4
  • Chromosome 20 Open Reading Frame 135 2
  • Protein ABHD16B 3
  • DJ591C20.1 3
  • EC 3.-.-.- 4

External Ids for ABHD16B Gene

Previous HGNC Symbols for ABHD16B Gene

  • C20orf135

Previous GeneCards Identifiers for ABHD16B Gene

  • GC20P062493

Summaries for ABHD16B Gene

GeneCards Summary for ABHD16B Gene

ABHD16B (Abhydrolase Domain Containing 16B) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD16A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD16B Gene

Genomics for ABHD16B Gene

Regulatory Elements for ABHD16B Gene

Enhancers for ABHD16B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ABHD16B on UCSC Golden Path with GeneCards custom track

Genomic Location for ABHD16B Gene

63,861,213 bp from pter
63,862,988 bp from pter
1,776 bases
Plus strand

Genomic View for ABHD16B Gene

Genes around ABHD16B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABHD16B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABHD16B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD16B Gene

Proteins for ABHD16B Gene

  • Protein details for ABHD16B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein ABHD16B
    Protein Accession:

    Protein attributes for ABHD16B Gene

    469 amino acids
    Molecular mass:
    52555 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ABHD16B Gene

Post-translational modifications for ABHD16B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABHD16B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ABHD16B Gene

Domains & Families for ABHD16B Gene

Gene Families for ABHD16B Gene

Protein Domains for ABHD16B Gene


Suggested Antigen Peptide Sequences for ABHD16B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the AB hydrolase superfamily. ABHD16 family.
  • Belongs to the AB hydrolase superfamily. ABHD16 family.
genes like me logo Genes that share domains with ABHD16B: view

Function for ABHD16B Gene

Enzyme Numbers (IUBMB) for ABHD16B Gene

Gene Ontology (GO) - Molecular Function for ABHD16B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD16B: view
genes like me logo Genes that share phenotypes with ABHD16B: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ABHD16B Gene

Localization for ABHD16B Gene

Subcellular locations from

Jensen Localization Image for ABHD16B Gene COMPARTMENTS Subcellular localization image for ABHD16B gene
Compartment Confidence
golgi apparatus 3
extracellular 2
cytosol 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ABHD16B Gene

Pathways & Interactions for ABHD16B Gene

SuperPathways for ABHD16B Gene

No Data Available

Interacting Proteins for ABHD16B Gene

Gene Ontology (GO) - Biological Process for ABHD16B Gene


No data available for Pathways by source and SIGNOR curated interactions for ABHD16B Gene

Drugs & Compounds for ABHD16B Gene

No Compound Related Data Available

Transcripts for ABHD16B Gene

mRNA/cDNA for ABHD16B Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(23) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ABHD16B Gene

Abhydrolase domain containing 16B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD16B Gene

No ASD Table

Relevant External Links for ABHD16B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ABHD16B Gene

mRNA expression in normal human tissues for ABHD16B Gene

Protein differential expression in normal tissues from HIPED for ABHD16B Gene

This gene is overexpressed in Pancreas (45.9) and Adipocyte (21.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ABHD16B Gene

Protein tissue co-expression partners for ABHD16B Gene

NURSA nuclear receptor signaling pathways regulating expression of ABHD16B Gene:


SOURCE GeneReport for Unigene cluster for ABHD16B Gene:

genes like me logo Genes that share expression patterns with ABHD16B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABHD16B Gene

Orthologs for ABHD16B Gene

This gene was present in the common ancestor of animals.

Orthologs for ABHD16B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ABHD16B 34
  • 86.99 (n)
  • 87.42 (a)
C13H20ORF135 35
  • 87 (a)
(Canis familiaris)
Mammalia ABHD16B 34
  • 82.27 (n)
  • 75.53 (a)
ABHD16B 35
  • 76 (a)
(Mus musculus)
Mammalia Abhd16b 34
  • 78.56 (n)
  • 85.47 (a)
Abhd16b 16
Abhd16b 35
  • 84 (a)
(Pan troglodytes)
Mammalia ABHD16B 34
  • 99.29 (n)
  • 98.72 (a)
ABHD16B 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Abhd16b 34
  • 78.82 (n)
  • 84.43 (a)
(Monodelphis domestica)
Mammalia ABHD16B 35
  • 57 (a)
(Danio rerio)
Actinopterygii abhd16a 35
  • 41 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1309 35
  • 29 (a)
(Caenorhabditis elegans)
Secernentea F37A4.1 35
  • 27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 20 (a)
CSA.9728 35
  • 35 (a)
Species where no ortholog for ABHD16B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ABHD16B Gene

Gene Tree for ABHD16B (if available)
Gene Tree for ABHD16B (if available)

Paralogs for ABHD16B Gene

Paralogs for ABHD16B Gene

(1) SIMAP similar genes for ABHD16B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ABHD16B: view

Variants for ABHD16B Gene

Sequence variations from dbSNP and Humsavar for ABHD16B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs2281534 - 63,861,569(-) GCACC(A/G/T)GCGCC reference, missense
rs2236152 -- 63,862,674(-) TCCTG(C/G)GCCAA reference, synonymous-codon
rs3215630 -- 63,862,541(-) GTGAC(-/A)GGGGG reference, frameshift-variant
rs2281535 -- 63,861,215(-) GTCTC(A/G)CTATG utr-variant-5-prime
rs2281536 -- 63,861,080(-) GGTGT(G/T)AGTCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ABHD16B Gene

Variant ID Type Subtype PubMed ID
nsv428381 CNV gain+loss 18775914
nsv469773 CNV gain 16826518
nsv509784 CNV insertion 20534489
nsv828804 CNV loss 20364138

Variation tolerance for ABHD16B Gene

Gene Damage Index Score: 5.43; 71.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ABHD16B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABHD16B Gene

Disorders for ABHD16B Gene

Relevant External Links for ABHD16B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ABHD16B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABHD16B Gene

Publications for ABHD16B Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 65
  2. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles R.A. … Easton D.F. (Nat. Genet. 2013) 3 65
  3. Genome-scale RNAi screen for host factors required for HIV replication. (PMID: 18976975) Zhou H. … Espeseth A.S. (Cell Host Microbe 2008) 3 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for ABHD16B Gene

Sources for ABHD16B Gene

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