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Aliases for ABHD16A Gene

Aliases for ABHD16A Gene

  • Abhydrolase Domain Containing 16A 2 3
  • BAT5 3 4 6
  • HLA-B Associated Transcript 5 2 3
  • Protein G5 3 4
  • D6S82E 3 6
  • NG26 3 4
  • Abhydrolase Domain-Containing Protein 16A 3
  • HLA-B-Associated Transcript 5 4
  • EC 3.-.-.- 4
  • PP199 3
  • G5 4

External Ids for ABHD16A Gene

Previous HGNC Symbols for ABHD16A Gene

  • BAT5

Previous GeneCards Identifiers for ABHD16A Gene

  • GC06M031440
  • GC06M031657
  • GC06M031661
  • GC06M031665
  • GC06M031696

Summaries for ABHD16A Gene

Entrez Gene Summary for ABHD16A Gene

  • A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

GeneCards Summary for ABHD16A Gene

ABHD16A (Abhydrolase Domain Containing 16A) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD16B.

Gene Wiki entry for ABHD16A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD16A Gene

Genomics for ABHD16A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ABHD16A Gene

Start:
31,686,949 bp from pter
End:
31,703,444 bp from pter
Size:
16,496 bases
Orientation:
Minus strand

Genomic View for ABHD16A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABHD16A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for ABHD16A Gene

Proteins for ABHD16A Gene

  • Protein details for ABHD16A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95870-ABHGA_HUMAN
    Recommended name:
    Abhydrolase domain-containing protein 16A
    Protein Accession:
    O95870
    Secondary Accessions:
    • A2BEY3
    • B7Z4R6
    • Q5SRR1
    • Q5SRR2
    • Q8WYH0
    • Q9NW33

    Protein attributes for ABHD16A Gene

    Size:
    558 amino acids
    Molecular mass:
    63243 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI17808.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI18401.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAM26084.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAM45793.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ABHD16A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABHD16A Gene

Proteomics data for ABHD16A Gene at MOPED

Post-translational modifications for ABHD16A Gene

  • Ubiquitination at Lys452
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ABHD16A Gene

Domains for ABHD16A Gene

Gene Families for ABHD16A Gene

HGNC:
  • ABHD :Abhydrolase domain containing

Protein Domains for ABHD16A Gene

Suggested Antigen Peptide Sequences for ABHD16A Gene

Graphical View of Domain Structure for InterPro Entry

O95870

UniProtKB/Swiss-Prot:

ABHGA_HUMAN :
  • O95870
Family:
  • Belongs to the AB hydrolase superfamily. ABHD16 family.
genes like me logo Genes that share domains with ABHD16A: view

Function for ABHD16A Gene

Enzyme Numbers (IUBMB) for ABHD16A Gene

Gene Ontology (GO) - Molecular Function for ABHD16A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 14667819
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD16A: view

Animal Model Products

CRISPR Products

miRNA for ABHD16A Gene

miRTarBase miRNAs that target ABHD16A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD16A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ABHD16A Gene

Localization for ABHD16A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABHD16A Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for ABHD16A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ABHD16A: view

No data available for Subcellular locations from COMPARTMENTS for ABHD16A Gene

Pathways for ABHD16A Gene

SuperPathways for ABHD16A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ABHD16A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD16A: view

No data available for Pathways by source for ABHD16A Gene

Transcripts for ABHD16A Gene

Unigene Clusters for ABHD16A Gene

Abhydrolase domain containing 16A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD16A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD16A Gene

No ASD Table

Relevant External Links for ABHD16A Gene

GeneLoc Exon Structure for
ABHD16A
ECgene alternative splicing isoforms for
ABHD16A

Expression for ABHD16A Gene

mRNA expression in normal human tissues for ABHD16A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ABHD16A Gene

SOURCE GeneReport for Unigene cluster for ABHD16A Gene Hs.388188

genes like me logo Genes that share expressions with ABHD16A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABHD16A Gene

Orthologs for ABHD16A Gene

This gene was present in the common ancestor of animals.

Orthologs for ABHD16A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ABHD16A 35
  • 99.64 (n)
  • 99.82 (a)
ABHD16A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ABHD16A 35
  • 93.85 (n)
  • 96.95 (a)
ABHD16A 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ABHD16A 35
  • 93.13 (n)
  • 96.06 (a)
ABHD16A 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abhd16a 35
  • 90.62 (n)
  • 96.06 (a)
Abhd16a 16
Abhd16a 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ABHD16A 36
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ABHD16A 36
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Abhd16a 35
  • 90.8 (n)
  • 95.34 (a)
lizard
(Anolis carolinensis)
Reptilia ABHD16A 36
  • 79 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia bat5-prov 35
tropical clawed frog
(Silurana tropicalis)
Amphibia abhd16a 35
  • 68.61 (n)
  • 72.91 (a)
Str.10410 35
zebrafish
(Danio rerio)
Actinopterygii abhd16a 35
  • 68.09 (n)
  • 68.53 (a)
abhd16a 36
  • 65 (a)
OneToMany
wufb55e01 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005364 35
  • 52.74 (n)
  • 46.15 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1309 35
  • 52.93 (n)
  • 45.96 (a)
CG1309 36
  • 41 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F37A4.1 35
  • 47.76 (n)
  • 37.89 (a)
F37A4.1 36
  • 33 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 33 (a)
ManyToMany
CSA.9728 36
  • 40 (a)
ManyToMany
Species with no ortholog for ABHD16A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ABHD16A Gene

ENSEMBL:
Gene Tree for ABHD16A (if available)
TreeFam:
Gene Tree for ABHD16A (if available)

Paralogs for ABHD16A Gene

Paralogs for ABHD16A Gene

Selected SIMAP similar genes for ABHD16A Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ABHD16A: view

Variants for ABHD16A Gene

Sequence variations from dbSNP and Humsavar for ABHD16A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs10298 -- 31,687,107(+) CATTT(A/C)CACAA utr-variant-3-prime, nc-transcript-variant
rs10573 -- 31,687,661(+) AAGTC(A/G)GGCCC reference, synonymous-codon, nc-transcript-variant
rs707917 -- 31,689,977(-) AAGGC(C/G)TCCCA intron-variant
rs707918 -- 31,686,955(-) CTATC(A/T)GGCTA utr-variant-3-prime, nc-transcript-variant
rs760294 -- 31,689,924(-) TGGGA(G/T)CCATG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ABHD16A Gene

Variant ID Type Subtype PubMed ID
nsv830627 CNV Loss 17160897
nsv884418 CNV Gain 21882294

Relevant External Links for ABHD16A Gene

HapMap Linkage Disequilibrium report
ABHD16A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABHD16A Gene

Disorders for ABHD16A Gene

No disorders were found for ABHD16A Gene.

No data available for UniProtKB/Swiss-Prot for ABHD16A Gene

Publications for ABHD16A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K. … Vandekerckhove J. (Nat. Biotechnol. 2003) 3 4
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  5. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PMID: 14656967) Xie T. … Hood L. (Genome Res. 2003) 3 4

Products for ABHD16A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ABHD16A
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD16A
  • Block miRNA regulation of ABHD16A using miScript Target Protectors

Sources for ABHD16A Gene

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