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Aliases for ABHD15 Gene

Aliases for ABHD15 Gene

  • Abhydrolase Domain Containing 15 2 3
  • EC 3.1.1.- 4

External Ids for ABHD15 Gene

Previous GeneCards Identifiers for ABHD15 Gene

  • GC17M024912
  • GC17M027887
  • GC17M024097

Summaries for ABHD15 Gene

GeneCards Summary for ABHD15 Gene

ABHD15 (Abhydrolase Domain Containing 15) is a Protein Coding gene. An important paralog of this gene is ABHD1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD15 Gene

Genomics for ABHD15 Gene

Regulatory Elements for ABHD15 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ABHD15 Gene

Start:
29,560,547 bp from pter
End:
29,567,137 bp from pter
Size:
6,591 bases
Orientation:
Minus strand

Genomic View for ABHD15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABHD15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD15 Gene

Proteins for ABHD15 Gene

  • Protein details for ABHD15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXT9-ABH15_HUMAN
    Recommended name:
    Abhydrolase domain-containing protein 15
    Protein Accession:
    Q6UXT9
    Secondary Accessions:
    • Q96EC5

    Protein attributes for ABHD15 Gene

    Size:
    468 amino acids
    Molecular mass:
    51771 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ABHD15 Gene

Proteomics data for ABHD15 Gene at MOPED

Post-translational modifications for ABHD15 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABHD15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ABHD15 Gene

Domains for ABHD15 Gene

Gene Families for ABHD15 Gene

HGNC:
  • ABHD :Abhydrolase domain containing

Protein Domains for ABHD15 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ABHD15 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UXT9

UniProtKB/Swiss-Prot:

ABH15_HUMAN :
  • Q6UXT9
Family:
  • Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
genes like me logo Genes that share domains with ABHD15: view

Function for ABHD15 Gene

Enzyme Numbers (IUBMB) for ABHD15 Gene

Gene Ontology (GO) - Molecular Function for ABHD15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD15: view

Phenotypes for ABHD15 Gene

GenomeRNAi human phenotypes for ABHD15:
genes like me logo Genes that share phenotypes with ABHD15: view

Animal Model Products

CRISPR Products

miRNA for ABHD15 Gene

miRTarBase miRNAs that target ABHD15

No data available for Molecular function , Animal Models , Transcription Factor Targeting and HOMER Transcription for ABHD15 Gene

Localization for ABHD15 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABHD15 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ABHD15 Gene COMPARTMENTS Subcellular localization image for ABHD15 gene
Compartment Confidence
extracellular 3
cytosol 1
golgi apparatus 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ABHD15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with ABHD15: view

Pathways for ABHD15 Gene

SuperPathways for ABHD15 Gene

No Data Available

Interacting Proteins for ABHD15 Gene

Gene Ontology (GO) - Biological Process for ABHD15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD15: view

No data available for Pathways by source for ABHD15 Gene

Transcripts for ABHD15 Gene

mRNA/cDNA for ABHD15 Gene

(62) Selected AceView cDNA sequences:
(4) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ABHD15 Gene

Abhydrolase domain containing 15:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD15

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ABHD15

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD15 Gene

No ASD Table

Relevant External Links for ABHD15 Gene

GeneLoc Exon Structure for
ABHD15
ECgene alternative splicing isoforms for
ABHD15

Expression for ABHD15 Gene

mRNA expression in normal human tissues for ABHD15 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ABHD15 Gene

SOURCE GeneReport for Unigene cluster for ABHD15 Gene Hs.106510

genes like me logo Genes that share expressions with ABHD15: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABHD15 Gene

Orthologs for ABHD15 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ABHD15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ABHD15 35
  • 99 (n)
  • 99.15 (a)
ABHD15 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ABHD15 35
  • 88.68 (n)
  • 89.74 (a)
ABHD15 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ABHD15 35
  • 88.2 (n)
  • 90.64 (a)
ABHD15 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abhd15 35
  • 85.01 (n)
  • 88.58 (a)
Abhd15 16
Abhd15 36
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ABHD15 36
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Abhd15 35
  • 84.09 (n)
  • 87.21 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8045 35
tropical clawed frog
(Silurana tropicalis)
Amphibia abhd15 35
  • 57.96 (n)
  • 57.72 (a)
zebrafish
(Danio rerio)
Actinopterygii ABHD15 36
  • 46 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 14 (a)
ManyToMany
EEB1 36
  • 14 (a)
ManyToMany
EHT1 36
  • 16 (a)
ManyToMany
Species with no ortholog for ABHD15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ABHD15 Gene

ENSEMBL:
Gene Tree for ABHD15 (if available)
TreeFam:
Gene Tree for ABHD15 (if available)

Paralogs for ABHD15 Gene

Paralogs for ABHD15 Gene

Pseudogenes.org Pseudogenes for ABHD15 Gene

genes like me logo Genes that share paralogs with ABHD15: view

Variants for ABHD15 Gene

Sequence variations from dbSNP and Humsavar for ABHD15 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs539307 -- 29,562,560(+) GGTCT(C/T)TCACC utr-variant-3-prime
rs542939 - 29,562,968(+) GTAGG(C/T)ATCCC reference, missense
rs636000 -- 29,564,846(+) CTAAG(A/G)AAGCC intron-variant
rs721478 -- 29,562,785(+) GCGCA(A/G)GAAGC reference, synonymous-codon
rs721479 -- 29,562,945(+) CGGAG(C/G)GGGTC synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for ABHD15 Gene

Variant ID Type Subtype PubMed ID
nsv833409 CNV Gain 17160897
nsv908033 CNV Loss 21882294
nsv521557 CNV Loss 19592680
dgv3135n71 CNV Loss 21882294
esv22811 CNV Loss 19812545

Relevant External Links for ABHD15 Gene

HapMap Linkage Disequilibrium report
ABHD15

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABHD15 Gene

Disorders for ABHD15 Gene

No disorders were found for ABHD15 Gene.

No data available for UniProtKB/Swiss-Prot for ABHD15 Gene

Publications for ABHD15 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for ABHD15 Gene

  • antibodies-online proteins for ABHD15
  • antibodies-online antibodies for ABHD15
  • antibodies-online kits for ABHD15

Sources for ABHD15 Gene

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