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Aliases for ABHD14A Gene

Aliases for ABHD14A Gene

  • Abhydrolase Domain Containing 14A 2 3
  • Abhydrolase Domain-Containing Protein 14A 3 4
  • Alpha/Beta Hydrolase Domain-Containing Protein 14A 3
  • EC 3.-.-.- 4
  • DORZ1 3

External Ids for ABHD14A Gene

Previous GeneCards Identifiers for ABHD14A Gene

  • GC03P051985
  • GC03P052005

Summaries for ABHD14A Gene

GeneCards Summary for ABHD14A Gene

ABHD14A (Abhydrolase Domain Containing 14A) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is ABHD14B.

UniProtKB/Swiss-Prot for ABHD14A Gene

  • Possible role in granule neuron development.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABHD14A Gene

Genomics for ABHD14A Gene

Regulatory Elements for ABHD14A Gene

Genomic Location for ABHD14A Gene

Start:
51,971,426 bp from pter
End:
51,981,200 bp from pter
Size:
9,775 bases
Orientation:
Plus strand

Genomic View for ABHD14A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABHD14A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABHD14A Gene

Proteins for ABHD14A Gene

  • Protein details for ABHD14A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUJ0-ABHEA_HUMAN
    Recommended name:
    Alpha/beta hydrolase domain-containing protein 14A
    Protein Accession:
    Q9BUJ0
    Secondary Accessions:
    • Q6UXU8
    • Q9Y3T7

    Protein attributes for ABHD14A Gene

    Size:
    271 amino acids
    Molecular mass:
    29765 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ88568.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ABHD14A Gene

Proteomics data for ABHD14A Gene at MOPED

Post-translational modifications for ABHD14A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABHD14A Gene

Antibody Products

No data available for DME Specific Peptides for ABHD14A Gene

Domains for ABHD14A Gene

Gene Families for ABHD14A Gene

HGNC:
  • ABHD :Abhydrolase domain containing

Protein Domains for ABHD14A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ABHD14A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BUJ0

UniProtKB/Swiss-Prot:

ABHEA_HUMAN :
  • Q9BUJ0
Family:
  • Belongs to the AB hydrolase superfamily. ABHD14 family.
genes like me logo Genes that share domains with ABHD14A: view

Function for ABHD14A Gene

Molecular function for ABHD14A Gene

UniProtKB/Swiss-Prot Function: Possible role in granule neuron development.

Enzyme Numbers (IUBMB) for ABHD14A Gene

Gene Ontology (GO) - Molecular Function for ABHD14A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ABHD14A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD14A

In Situ Assay Products

Flow Cytometry Products

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ABHD14A Gene

Localization for ABHD14A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABHD14A Gene

Cytoplasm. Membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ABHD14A Gene COMPARTMENTS Subcellular localization image for ABHD14A gene
Compartment Confidence
cytosol 4
chloroplast 2
extracellular 2
nucleus 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for ABHD14A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with ABHD14A: view

Pathways for ABHD14A Gene

SuperPathways for ABHD14A Gene

No Data Available

Interacting Proteins for ABHD14A Gene

Gene Ontology (GO) - Biological Process for ABHD14A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ABHD14A: view

No data available for Pathways by source for ABHD14A Gene

Transcripts for ABHD14A Gene

mRNA/cDNA for ABHD14A Gene

Unigene Clusters for ABHD14A Gene

Abhydrolase domain containing 14A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ABHD14A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ABHD14A Gene

No ASD Table

Relevant External Links for ABHD14A Gene

GeneLoc Exon Structure for
ABHD14A
ECgene alternative splicing isoforms for
ABHD14A

Expression for ABHD14A Gene

mRNA expression in normal human tissues for ABHD14A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ABHD14A Gene

SOURCE GeneReport for Unigene cluster for ABHD14A Gene Hs.534400

genes like me logo Genes that share expressions with ABHD14A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABHD14A Gene

Orthologs for ABHD14A Gene

This gene was present in the common ancestor of animals.

Orthologs for ABHD14A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ABHD14A 35
  • 88.93 (n)
  • 87.97 (a)
dog
(Canis familiaris)
Mammalia ABHD14A 35
  • 91.02 (n)
  • 90.41 (a)
ABHD14A 36
  • 69 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abhd14a 35
  • 83.4 (n)
  • 81.38 (a)
Abhd14a 16
Abhd14a 36
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ABHD14A 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Abhd14a 35
  • 84.16 (n)
  • 82.64 (a)
chicken
(Gallus gallus)
Aves ABHD14A 36
  • 51 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ABHD14A 36
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia abhd14a 35
  • 57.32 (n)
  • 47.66 (a)
zebrafish
(Danio rerio)
Actinopterygii abhd14a 35
  • 61.35 (n)
  • 55.4 (a)
abhd14a 36
  • 46 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y55F3AM.10 36
  • 28 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
ManyToMany
CSA.1288 36
  • 31 (a)
ManyToMany
Species with no ortholog for ABHD14A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ABHD14A Gene

ENSEMBL:
Gene Tree for ABHD14A (if available)
TreeFam:
Gene Tree for ABHD14A (if available)

Paralogs for ABHD14A Gene

Paralogs for ABHD14A Gene

Selected SIMAP similar genes for ABHD14A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ABHD14A: view

Variants for ABHD14A Gene

Sequence variations from dbSNP and Humsavar for ABHD14A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
VAR_031390 -
VAR_031391 -

Structural Variations from Database of Genomic Variants (DGV) for ABHD14A Gene

Variant ID Type Subtype PubMed ID
nsv520211 CNV Gain 19592680
nsv508922 CNV Insertion 20534489
nsv876780 CNV Loss 21882294
dgv5134n71 CNV Loss 21882294
dgv5135n71 CNV Loss 21882294
nsv519445 CNV Gain+Loss 19592680

Relevant External Links for ABHD14A Gene

HapMap Linkage Disequilibrium report
ABHD14A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABHD14A Gene

Disorders for ABHD14A Gene

(1) University of Copenhagen DISEASES for ABHD14A Gene

genes like me logo Genes that share disorders with ABHD14A: view

No data available for UniProtKB/Swiss-Prot for ABHD14A Gene

Publications for ABHD14A Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A high-throughput approach for measuring temporal changes in the interactome. (PMID: 22863883) Kristensen A.R. … Foster L.J. (Nat. Methods 2012) 3
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for ABHD14A Gene

Sources for ABHD14A Gene

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