ABHD13 Gene
protein-coding GIFtS: 45
GCID: GC13P108870
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abhydrolase domain containing 13(Previous name: chromosome 13 open reading frame 6 )
(Previous symbol: C13orf6)
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Aliases
for ABHD13 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Abhydrolase Domain Containing 131 2 | | FLJ149061 | | C13orf61 2 3 | | Chromosome 13 Open Reading Frame 61 | | BEM46L11 2 | | RP11-153I24.22 | | BA153I24.21 | | EC 3.-.-.-3 | | Abhydrolase Domain-Containing Protein 132 3 | | |
Export aliases for ABHD13 gene to outside databasesPrevious GC identifers: GC13P107670 GC13P089461 |
Summaries
for ABHD13 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ABHD13 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_009952.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABHD13 gene promoter:
Nkx3-1 Nkx3-1 v4 RP58 p300 STAT5A Nkx3-1 v1 POU6F1 (c2) Nkx3-1 v2 Nkx3-1 v3 ZID
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABHD13
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABHD13 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q33.3 Ensembl cytogenetic band: 13q33.3 HGNC cytogenetic band: 13q33.2ABHD13 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P108870: view genomic region
(about GC identifiers)
Start:
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108,870,727 bp from pter |
End:
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108,886,603 bp from pter |
Size:
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15,877 bases |
Orientation:
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plus strand |
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Proteins
for ABHD13 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ABHDD_HUMAN, Q7L211 (See
protein sequence)Recommended Name: Alpha/beta hydrolase domain-containing protein 13 Size: 337 amino acids; 38548 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Potential)
Sequence caution: Sequence=AAH70226.1; Type=Erroneous initiation; Sequence=AK075195; Type=Erroneous termination;Positions=167; Note=Translated as Leu; Sequence=BAB55387.1; Type=Erroneous initiation;
Secondary accessions: B3KWE7 Q8NBW1 Q96JX9Explore the universe of human proteins at neXtProt for ABHD13: NX_Q7L211
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7L211
ABHD13 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116248.2
ENSEMBL proteins: ENSP00000365063
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
ABHD13 for ontologies About GeneDecksing
ABHD13 Antibody Products:
Assay Products for ABHD13: |
Protein
Domains /
Families
for ABHD13 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q7L211 1 Blocks protein family: IPB003089 Alpha/beta hydrolase fold signature
UniProtKB/Swiss-Prot: ABHDD_HUMAN, Q7L211Similarity: Belongs to the serine esterase family |
Function
for ABHD13 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Enzyme Number (IUBMB): EC 3.-.-.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABHD13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABHD13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ABHD13 (NM_032859) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABHD13 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABHD13 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABHD13 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016787 | hydrolase activity |
IEA | -- |
ABHD13 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ABHD13:
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Pathways & Interactions
for ABHD13 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABHD13
5/7 Interacting proteins for ABHD13 (Q7L2113) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
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Drugs & Compounds
for ABHD13 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ABHD13
Search CenterWatch for drugs/clinical trials and news about ABHD13 / ABHDD
|
Transcripts
for ABHD13 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABHD13 gene: NM_032859.2 Unigene Cluster for ABHD13: Abhydrolase domain containing 13 Hs.183528 [show with all ESTs]Unigene Representative Sequence: NM_0328591 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000375898(uc001vqq.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABHD13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABHD13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ABHD13 (NM_032859) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABHD13 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABHD13 |
Additional cDNA sequence: AK027812.1 BC018608.1 BC022566.1 BC070226.1 BX647428.1 3 DOTS entries: DT.407487 DT.97823458 DT.92420168 24/86 AceView cDNA sequences (see all 86): AA403049 AK027812 CR597257 AA489076 BE018217 BU677103 BE047235 BU675394 NM_032859 AI281417 BM764222 AA548082 BC018608 AK124864 AW451214 BC070226 BC022566 CR609193 BE301702 AI282621 CB852981 AW085198 AA405672 AI911560
GeneLoc Exon Structure
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Expression
for ABHD13 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABHD13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAAGCAAAC
About this image
See ABHD13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABHD13
SOURCE GeneReport for Unigene cluster: Hs.183528
SABiosciences Custom PCR Arrays for ABHD13
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABHD13
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABHD13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABHD13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABHD13 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABHD13 |
Orthologs
for ABHD13 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ABHD13 gene from 9/33 species (see all 33) About this table
ENSEMBL Gene Tree for ABHD13 (if available)
TreeFam Gene Tree for ABHD13 (if available) |
Paralogs
for ABHD13 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABHD13 gene
- FAM108C12 FAM108A12 FAM108B12
ABHD13 for paralogs About GeneDecksing
|
Genomic Variants
for ABHD13 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABHD13 (108870727 - 108886603 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for ABHD13
5 CNVs: 87019 87020 87018 76480 76481 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABHD13 |
|
Disorders
/ Diseases
for ABHD13 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABHD13 for disorders About GeneDecksing
4  diseases for ABHD13: About MalaCardsconduct disorder adhd tuberculosis mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: ABHD13 (1 document)
Export disorders for ABHD13 gene to outside databases
|
Publications
for ABHD13 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABHD13 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ABHD13) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1 Hosgood H.D....Lan Q. (2009)
- Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)1 Anney R.J....Gill M. (2008)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ABHD13 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ABHD13 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABHD13 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABHD13 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ABHD13 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for ABHD13 gene:
Search GeneIP for patents involving ABHD13
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ABHD13 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ABHD13 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABHD13 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABHD13 | | | OriGene Protein Over-expression Lysate for ABHD13 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABHD13 | | OriGene 3'-UTR Clone for ABHD13 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABHD13 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABHD13 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABHD13 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABHD13 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABHD13 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABHD13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABHD13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABHD13 |
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 |  |  |  | |
| | | | Search Tocris compounds for ABHD13 |
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 | | | ABHD13 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABHD13 |
|  |  |  | | | | ThermoFisher Antibodies for ABHD13 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABHD13 |
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