Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ABHD1 Gene

protein-coding   GIFtS: 47
GCID: GC02P027349

Abhydrolase Domain Containing 1

  Search for ABHD1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Abhydrolase Domain Containing 11 2
LABH12 3 5
Lung Alpha/Beta Hydrolase 12 3
Abhydrolase Domain-Containing Protein 12
EC 3.1.1.-3
EC 3.1.18

External Ids:    HGNC: 175531   Entrez Gene: 846962   Ensembl: ENSG000001439947   OMIM: 6121955   UniProtKB: Q96SE03   

Export aliases for ABHD1 gene to outside databases

Previous GC identifers: GC02P027268 GC02P027439 GC02P027321 GC02P027258 GC02P027088


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABHD1 Gene:
This gene is a member of the AB hydrolase superfamily and encodes a protein with an alpha/beta hydrolase fold.
This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and catalytic
functions. (provided by RefSeq, Jul 2008)

GeneCards Summary for ABHD1 Gene: 
ABHD1 (abhydrolase domain containing 1) is a protein-coding gene. GO annotations related to this gene include molecular_function and carboxylesterase activity. An important paralog of this gene is ABHD15.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ABHD1 gene promoter:
         NF-1/L   NF-1   Elk-1   NRSF form 1   p300   Nkx2-2   CUTL1   NRSF form 2   HNF-4alpha1   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABHD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ABHD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABHD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p23.3

ABHD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABHD1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P027349:  view genomic region     (about GC identifiers)

Start:
27,346,657 bp from pter      End:
27,353,680 bp from pter
Size:
7,024 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ABHD1_HUMAN, Q96SE0 (See protein sequence)
Recommended Name: Abhydrolase domain-containing protein 1  
Size: 405 amino acids; 45207 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Potential)
Secondary accessions: Q05BY3 Q53SZ1 Q8IXQ7

Explore the universe of human proteins at neXtProt for ABHD1: NX_Q96SE0

Explore proteomics data for ABHD1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96SE0

  • 4/6 DME Specific Peptides for ABHD1 (Q96SE0) (see all 6)
     VVFNNRG  ALYLGYYW  NTEDLETV  GGHIGFLEG 

    ABHD1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ABHD1 Protein Expression
    REFSEQ proteins: NP_115993.3  
    ENSEMBL proteins: 
     ENSP00000410756   ENSP00000326491   ENSP00000390390   ENSP00000397522  

    Human Recombinant Protein Products for ABHD1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ABHD1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ABHD1
    GenScript Custom Purified and Recombinant Proteins Services for ABHD1
    Novus Biologicals ABHD1 Protein
    Novus Biologicals ABHD1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ABHD1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane NAS12735795

    ABHD1 for ontologies           About GeneDecksing



    ABHD1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ABHD1
    GenScript Custom Superior Antibodies Services for ABHD1
    Novus Biologicals ABHD1 Antibodies
    Abcam antibodies for ABHD1
    Cloud-Clone Corp. Antibodies for ABHD1 
    Search ThermoFisher Antibodies for ABHD1
    LSBio Antibodies in human, mouse, rat for ABHD1 

    Assay Products for ABHD1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ABHD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ABHD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ABHD1 
    Cloud-Clone Corp. CLIAs for ABHD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ABHD: Abhydrolase domain containing

    2 InterPro protein domains:
     IPR000952 UPF0017_hydro-like_CS
     IPR012020 AB-Hydro_YheT

    Graphical View of Domain Structure for InterPro Entry Q96SE0

    ProtoNet protein and cluster: Q96SE0

    1 Blocks protein domain: IPB000952 Protein of unknown function UPF0017

    UniProtKB/Swiss-Prot: ABHD1_HUMAN, Q96SE0
    Similarity: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family


    ABHD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Enzyme Numbers (IUBMB): EC 3.1.12 EC 3.1.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0004091carboxylesterase activity IEA--
         
    ABHD1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ABHD1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ABHD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ABHD1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ABHD1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABHD1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ABHD1:
    hsa-miR-3145-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ABHD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABHD1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ABHD1
    Sirion Biotech Customized adenovirus for overexpression of ABHD1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ABHD1 (see all 6)
    OriGene ORF clones in mouse, rat for ABHD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ABHD1 (NM_021160)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABHD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABHD1
    Sirion Biotech Customized lentivirus for stable overexpression of ABHD1 
                         Customized lentivirus expression plasmids for stable overexpression of ABHD1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ABHD1
    Search LifeMap BioReagents cell lines for ABHD1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABHD1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABHD1

    5/22 Interacting proteins for ABHD1 (Q96SE03) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000096150P622693I2D: score=1 
    ENSG00000223367P622693I2D: score=1 
    ENSG00000226225P622693I2D: score=1 
    ENSG00000235650P622693I2D: score=1 
    RPS18P622693I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    ABHD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ABHD1

    Search CenterWatch for drugs/clinical trials and news about ABHD1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ABHD1 gene (2 alternative transcripts): 
    NM_032604.3  NM_152870.1  

    Unigene Cluster for ABHD1:

    Abhydrolase domain containing 1
    Hs.375791  [show with all ESTs]
    Unigene Representative Sequence: BC039576
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000489120 ENST00000448950(uc002riu.3 uc002riv.3) ENST00000316470(uc002rit.3)
    ENST00000420647 ENST00000416071 ENST00000496739
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABHD1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ABHD1:
    hsa-miR-3145-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ABHD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABHD1
    Clone
    Products:
         
    OriGene clones in human, mouse for ABHD1 (see all 6)
    OriGene ORF clones in mouse, rat for ABHD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ABHD1 (NM_021160)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABHD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABHD1
    Sirion Biotech Customized lentivirus for stable overexpression of ABHD1 
                         Customized lentivirus expression plasmids for stable overexpression of ABHD1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ABHD1
    OriGene qSTAR qPCR primer pairs in human, mouse for ABHD1
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ABHD1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABHD1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABHD1

    Additional mRNA sequence: 

    AY033290.1 BC039576.1 BC056403.1 

    6 DOTS entries:

    DT.101985109  DT.40204293  DT.95155684  DT.91798562  DT.443424  DT.100877117 

    24/44 AceView cDNA sequences (see all 44):

    BU739913 BC039576 NM_152870 AI678612 NM_032604 AA432315 BU740385 AW444693 
    T34011 AI554273 BC031868 AA382999 AY033290 AA428655 BM720460 BX367193 
    BC028378 BI827051 BI825476 AA609036 AX748133 BI829504 AI028742 BC056403 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ABHD1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8
    SP1:                          -                                                   
    SP2:              -           -     -                       -                     
    SP3:              -           -                                                   
    SP4:                                                                              
    SP5:                                                                              


    ECgene alternative splicing isoforms for ABHD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ABHD1 expression in normal human tissues (normalized intensities)      ABHD1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCGCCTCT
    ABHD1 Expression
    About this image


    ABHD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             sperm   
     
     Thymus (Hematopoietic System)
             Thymus
     
     Brain (Nervous System)
             Meninges

    See ABHD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ABHD1

    SOURCE GeneReport for Unigene cluster: Hs.375791

    UniProtKB/Swiss-Prot: ABHD1_HUMAN, Q96SE0
    Tissue specificity: Ubiquitously expressed

        SABiosciences Custom PCR Arrays for ABHD1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ABHD1
    OriGene qSTAR qPCR primer pairs in human, mouse for ABHD1
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ABHD1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABHD1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABHD1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABHD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ABHD1 gene from 7/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Abhd15 abhydrolase domain containing 1   --   5 (16.90 cM) 30950066 
    lizard
    (Anolis carolinensis)
    Reptilia ABHD16
    Uncharacterized protein
    59(a)
    1 ↔ 1
    AAWZ02039802(4010-6700)
    African clawed frog
    (Xenopus laevis)
    Amphibia abhd1-prov2 abhydrolase domain containing 3 73.61(n)    BC046710.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hydr16
    alpha/beta hydrolase 1
    28(a)
    1 → many
    2R(5019992-5022958)
    worm
    (Caenorhabditis elegans)
    Secernentea C44C1.56
    Y60A3A.76
    Protein Y60A3A.7
    31(a)
    31(a)
    many ↔ many
    many ↔ many
    X(975526-978445)
    V(19955460-19958912)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YMR210W)4 Putative acyltransferase with similarity to Eeb1p and more   --   13(687516-688865) 855250  NP_013937.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G499501 embryogenesis-associated protein-like protein 43.53(n)
    28.82(a)
      835059  NM_124374.4  NP_199806.1 


    ENSEMBL Gene Tree for ABHD1 (if available)
    TreeFam Gene Tree for ABHD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ABHD1 gene
    ABHD152  ABHD32  ABHD22  
    1 SIMAP similar gene for ABHD1 using alignment to 5 protein entries:     ABHD1_HUMAN (see all proteins):
    ABHD3

    ABHD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/232 SNPs in ABHD1 are shown (see all 232)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0310884
    ----see VAR_0310882 W C mis40--------
    VAR_0310874
    ----see VAR_0310872 D E mis40--------
    rs134285321,2
    C,F,H--27267745(+) catggA/Gccagt 1 -- us2k16Minor allele frequency- G:0.01NS EA NA WA 422
    rs1429734351,2
    --27267893(+) CCAGGC/TCACTT 1 -- us2k10--------
    rs1472252741,2
    --27267928(+) TGTGCC/TTGAGT 1 -- us2k10--------
    rs1405763621,2
    --27267972(+) AAGAGG/TTCACT 1 -- us2k10--------
    rs1151772931,2
    C,F--27268348(+) GATGCC/GAAATA 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1113200721,2
    C,F--27268476(+) GTCCCG/AGGGAT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs803092971,2
    C,F--27268478(+) CCCAGG/AGATGG 1 -- us2k11Minor allele frequency- A:0.06EA 120
    rs76055261,2
    C,F,A,H--27268562(+) TACCAG/AGTCCT 1 -- us2k125Minor allele frequency- A:0.31NS EA NA WA 2770

    HapMap Linkage Disequilibrium report for ABHD1 (27346657 - 27353680 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ABHD1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv833603CNV Loss17160897
    nsv873753CNV Loss21882294
    nsv455974CNV Loss19166990
    nsv817673CNV Gain17921354

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ABHD1
    DNA2.0 Custom Variant and Variant Library Synthesis for ABHD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ABHD1 for disorders           About MalaCards
    OMIM gene information: 612195    OMIM disorders: --


    ABHD1 for disorders           About GeneDecksing


    Export disorders for ABHD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ABHD1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ABHD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12. (PubMed id 12735795)1, 2 Edgar A.J. (2003)
    4. Cloning and tissue distribution of three murine alpha/beta hydrolase fold protein cDNAs. (PubMed id 11922611)1, 3 Edgar A.J. and Polak J.M. (2002)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84696 HGNC: 17553 AceView: ABHD1 Ensembl:ENSG00000143994 euGenes: HUgn84696
    ECgene: ABHD1 H-InvDB: ABHD1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ABHD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ABHD1 gene:
    Search GeneIP for patents involving ABHD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ABHD1  
     OriGene qPCR primer pairs and template standards for ABHD1   OriGene Protein Over-expression Lysate for ABHD1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ABHD1  
     OriGene qSTAR qPCR primer pairs in human, mouse for ABHD1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ABHD1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ABHD1   OriGene Custom Protein Services for ABHD1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABHD1
     QIAGEN SeqTarget long-range PCR primers for resequencing ABHD1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABHD1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABHD1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABHD1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABHD1
     GenScript Custom Purified and Recombinant Proteins Services for ABHD1 GenScript cDNA clones with any tag delivered in your preferred vector for ABHD1
     GenScript Custom Assay Services for ABHD1 GenScript Custom Superior Antibodies Services for ABHD1
     GenScript Custom overexpressing Cell Line Services for ABHD1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ABHD1 promoter
     Search Chromatin IP Primers for ABHD1
     RT2 qPCR Primer Assay in human, mouse / rat ABHD1
     Search GNC Networks for ABHD1
     SABiosciences Custom PCR Arrays for ABHD1
     Search Tocris compounds for ABHD1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ABHD1 antibodies
     ABHD1 proteins
     ABHD1 lysates
     Antibodies for ABHD1
     See all of Abcam's Antibodies, Kits and Proteins for ABHD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ABHD1
     Antibodies for ABHD1
     ELISAs for ABHD1
     CLIAs for ABHD1
     Search LifeMap BioReagents cell lines for ABHD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABHD1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ABHD1
     SwitchGear Promoter luciferase reporter plasmids for ABHD1
     Search ThermoFisher Antibodies for ABHD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABHD1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ABHD1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ABHD1
    Customized:
     lentivirus for stable overexpression of ABHD1
     lentivirus expression plasmids for stable overexpression of ABHD1
     adenovirus for overexpression of ABHD1
     LSBio Antibodies in human, mouse, rat for ABHD1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ABHD1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4