ABCG8 Gene
protein-coding GIFtS: 59
GCID: GC02P043977
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ATP-binding cassette, sub-family G (WHITE), member 8(Previous names: ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin...)
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Aliases for ABCG8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family G (WHITE), Member 81 2 | | ATP-Binding Cassette, Subfamily G, Member 82 | | GBD41 2 5 | | Sterolin 22 | | ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (Sterolin 2)1 | | Sterolin-23 | | STSL2 | | Sterolin-23 | | ATP-Binding Cassette Sub-Family G Member 82 | | |
Export aliases for ABCG8 gene to outside databasesPrevious GC identifers: GC02P044065 GC02P044234 GC02P044040 GC02P043802 |
Summaries for ABCG8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ABCG8: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily.The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promoteexcretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen.It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed onchromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterolaccumulation and atherosclerosis, and have been observed in patients with sitosterolemia. (provided by RefSeq, Jul2008) UniProtKB/Swiss-Prot: ABCG8_HUMAN, Q9H221Function: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterolin and out of the enterocytes and in the selective sterol excretion by the liver into bile Gene Wiki entry for ABCG8
|
Genomic Views for ABCG8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ABCG8 gene promoter: SRF AML1a HOXA3 SRF (504 AA) Evi-1 PPAR-alpha POU2F1 POU2F1a c-Myb ATF6 Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCG8
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCG8 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2p21ABCG8 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P043977: view genomic region
(about GC identifiers)
Start:
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44,066,103 bp from pter |
End:
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44,105,605 bp from pter |
Size:
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39,503 bases |
Orientation:
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plus strand |
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Proteins for ABCG8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ABCG8_HUMAN, Q9H221 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family G member 8 Size: 673 amino acids; 75679 Da
Subunit: May form heterodimers with ABCG5 or be tightly coupled to ABCG5 along a pathway regulating diatery-sterolabsorption and excretion
Subcellular location: Membrane; Multi-pass membrane protein (Probable)
Caution: Seems to have a defective ATP-binding region
Secondary accessions: Q53QN8Alternative splicing: 2 isoforms: Q9H221-1 Q9H221-2 (Minor form detected in approximately 10% of the cDNA clones)Explore the universe of human proteins at neXtProt for ABCG8: NX_Q9H221
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H221 ABCG8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_071882.1 ENSEMBL proteins: ENSP00000272286 Reactome Protein details: Q9H221 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ABCG8 for ontologies About GeneDecksing
ABCG8 Antibody Products: Assay Products for ABCG8: |
Protein
Domains / Families for ABCG8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCG8 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H221ProtoNet protein and cluster: Q9H221 UniProtKB/Swiss-Prot: ABCG8_HUMAN, Q9H221Similarity: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204)subfamilySimilarity: Contains 1 ABC transmembrane type-2 domainSimilarity: Contains 1 ABC transporter domain |
Function for ABCG8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ABCG8_HUMAN, Q9H221Function: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterolin and out of the enterocytes and in the selective sterol excretion by the liver into bile
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG8 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG8 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ABCG8 (NM_022437) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCG8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCG8  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCG8 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ABCG8 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ABCG8: Animal Models: Mouse knock-outs for ABCG8: Abcg5/Abcg8Abcg5/tm1Hobb Abcg8tm1Elk 4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Abcg8):
ABCG8 for phenotypes About GeneDecksing
|
Pathways & Interactions for ABCG8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | Metabolism | | | 3 | Statin Pathway, Pharmacodynamics | | | 4 | Trafficking of dietary sterols | | | 5 | Vitamin A and carotenoid metabolism | |
Pathway sources See GeneCards unified pathways Show all pathways
2 BioSystems Pathways for ABCG8 
5/7
Reactome Pathways for ABCG8 (see all 7) 1 PharmGKB Pathway for ABCG8 3
Kegg Pathways (Kegg details for ABCG8):
ABCG8 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABCG8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
 5/8 Interacting proteins for ABCG8 (Q9H2212, 3 ENSP000002722864) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15): About this table
ABCG8 for ontologies About GeneDecksing
|
Drugs & Compounds for ABCG8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ABCG8 for compounds About GeneDecksing
Browse Tocris compounds for ABCG8 10 Novoseek chemical compound relationships for ABCG8 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sterol |
89.2 |
49 |
15520451 (3), 15044450 (3), 15860120 (2), 12208868 (2) (see all 31) |
| sitosterol |
83.9 |
5 |
15040800 (2), 12488046 (1), 15331430 (1) |
| lathosterol |
80.7 |
2 |
15331430 (1), 15210841 (1) |
| ezetimibe |
78.7 |
2 |
15737409 (1), 19013286 (1) |
| cholesterol |
74.7 |
88 |
15175352 (4), 19019257 (4), 18581044 (3), 16250035 (3) (see all 45) |
| cholestanol |
52.9 |
1 |
15175352 (1) |
| atp |
44.6 |
18 |
11668628 (2), 16893193 (2), 14657202 (1), 15121760 (1) (see all 14) |
| lipid |
31.8 |
6 |
15311998 (1), 15860120 (1), 17098593 (1), 16980816 (1) (see all 5) |
| phospholipid |
4.5 |
1 |
16250035 (1) |
| glucose |
0 |
1 |
17543849 (1) |
Search CenterWatch for drugs/clinical trials and news about ABCG8 
|
Transcripts for ABCG8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ABCG8 gene: NM_022437.2 Unigene Cluster for ABCG8: ATP-binding cassette, sub-family G (WHITE), member 8 Hs.413931 [show with all ESTs]Unigene Representative Sequence: NM_0224371 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000272286(uc002rtq.3 uc010yoa.2)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG8 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG8 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ABCG8 (NM_022437) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCG8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCG8  |
Additional cDNA sequence: AF320294.1 AF324494.1 BC113657.1 BC143564.1 3 DOTS entries: DT.97830216 DT.102880 DT.75131703 21 AceView cDNA sequences: NM_022437 AF320294 BX481838 H55780 AA700584 CB162405 BX096032 AF324494 AA033788 AA701645 BX482362 AA034046 BX109661 R89160 T84531 R89063 H60686 T91380 H55873 H59871 R00110 GeneLoc Exon Structure
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Expression for ABCG8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCG8 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GGCTCCAAAA
About this image See ABCG8 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ABCG8
SOURCE GeneReport for Unigene cluster: Hs.413931 UniProtKB/Swiss-Prot: ABCG8_HUMAN, Q9H221Tissue specificity: Strongly expressed in the liver, lower levels in the small intestine and colon. Detectable in awide variety of human tissues SABiosciences Expression via Pathway-Focused PCR Array including ABCG8:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCG8 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCG8 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCG8 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCG8 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCG8 |
Orthologs for ABCG8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ABCG8 gene from 8/22 species (see all 22) About this table
ENSEMBL Gene Tree for ABCG8 (if available) TreeFam Gene Tree for ABCG8 (if available)  |
Paralogs for ABCG8 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ABCG8 gene
- ABCG12 ABCA12 ABCA102 ABCA132 ABCA32 ABCA82 ABCG42 ABCA122
- ABCA42 ABCA72 ABCG52 ABCA22 ABCA92 ABCA62 ABCA52 ABCG22
2 SIMAP similar genes for ABCG8 using alignment to 4 protein entries: ABCG8_HUMAN (see all proteins):ABCG2 ABCG5
ABCG8 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ABCG8 PGOHUM00000235393
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Genomic Variants for ABCG8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 2 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCG8 (44066103 - 44105605 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 6 variations for ABCG8 5 CNVs: 73443 89620 50500 78526 50499 1 Indel: 50498 Human Gene Mutation Database (HGMD): ABCG8
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCG8 |
|
Disorders
/ Diseases for ABCG8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCG8 for disorders About GeneDecksing
OMIM gene information: 605460 OMIM disorders: 210250 611465 UniProtKB/Swiss-Prot: ABCG8_HUMAN, Q9H221
Genetic variations in ABCG8 can be associated with susceptibility to gallbladder disease type 4 (GBD4)[MIM:611465]. With an overall prevalence of 10-20%, gallstone disease (cholelithiasis) represents one of the mostfrequent and economically relevant health problems of industrialized countries Defects in ABCG8 are a cause of sitosterolemia (STSL) [MIM:210250]; also known as phytosterolemia or shellfishsterolemia. It is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterolsincluding cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile.Sitosterolemia patients have hypercholesterolemia, very high levels of plant sterols in the plasma, and frequentlydevelop tendon and tuberous xanthomas, accelerated atherosclerosis and premature coronary artery disease 20/22 diseases for ABCG8 (see all 22): About MalaCardssitosterolemia atherosclerosis cholesterol gallbladder disease 4 biliary tract cancer macrothrombocytopenia gallbladder disease hypercholesterolemia coronary heart disease familial hypercholesterolemia aortic atherosclerosis insulin resistance cholelithiasis gallbladder cancer vascular disease thrombocytopenia kidney disease twinning colorectal cancer breast cancer
2 diseases from the University of Copenhagen DISEASES database for ABCG8:Cholelithiasis Atherosclerosis 4 Novoseek disease relationships for ABCG8 gene About this table
Genetic Association Database (GAD): ABCG8 Human Genome Epidemiology (HuGE) Navigator: ABCG8 (58 documents) Export disorders for ABCG8 gene to outside databases
|
Publications for ABCG8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCG8 gene, integrated from 9 sources (see all 150): (articles sorted by number of sources associating them with ABCG8) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. (PubMed id 11099417)1, 2, 3 Berge K.E.... Hobbs H.H. (2000)
- Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin- 2, encoded by ABCG5 and ABCG8, respectively. (PubMed id 11452359)1, 2, 9 Lu K....Patel S.B. (2001)
- Mutations in ATP-cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia. (PubMed id 11668628)1, 2, 9 Hubacek J.A.... Hobbs H.H. (2001)
- Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity. (PubMed id 15175352)1, 4, 9 Gylling H....Miettinen T.A. (2004)
- Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteers. (PubMed id 15520451)1, 4, 9 Plat J....Mensink R.P. (2005)
- Polymorphisms in ABCG5 and ABCG8 transporters and plasma cholesterol levels. (PubMed id 15311998)1, 4, 9 Hubacek J.A....Poledne R. (2004)
- Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol. (PubMed id 17626266)1, 3, 9 Grunhage F....Lammert F. (2007)
- ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects. (PubMed id 15816807)1, 4, 9 Miwa K....Mabuchi H. (2005)
- ATP-binding cassette transporter G8 gene as a determinant of apolipoprotein B-100 kinetics in overweight men. (PubMed id 15331430)1, 4, 9 Chan D.C....van Bockxmeer F.M. (2004)
- ATP binding cassette G5 C1950G polymorphism may affect blood cholesterol concentrations in humans. (PubMed id 12220438)1, 4, 9 Weggemans R.M....Katan M.B. (2002)
|
External Searches for ABCG8 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ABCG8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCG8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABCG8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ABCG8 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ABCG8 | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q9H221 |
|
| | |
About This Section
| Patent Information for ABCG8 gene: Search GeneIP for patents involving ABCG8
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ABCG8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for ABCG8 | | OriGene shRNA RFP for ABCG8 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCG8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCG8 | | OriGene Protein Over-expression Lysate for ABCG8 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ABCG8 | | OriGene 3'-UTR Clone for ABCG8 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG8 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ABCG8 | | OriGene Custom Protein Services for ABCG8 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCG8 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCG8 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCG8 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCG8 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCG8 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCG8 |
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| | | Search Tocris compounds for ABCG8 |
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 | | ABCG8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCG8 |
|  |  |  | | | ThermoFisher Antibodies for ABCG8 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCG8 |
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