ABCG5 Gene
protein-coding GIFtS: 59
GCID: GC02M044039
|
|
ATP-binding cassette, sub-family G (WHITE), member 5
| |
Aliases
for ABCG5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family G (WHITE), Member 51 2 | | Sterolin 12 | | STSL1 2 | | Sterolin-13 | | ATP-Binding Cassette Sub-Family G Member 52 | | Sterolin-13 | | ATP-Binding Cassette, Subfamily G, Member 52 | | |
Export aliases for ABCG5 gene to outside databasesPrevious GC identifers: GC02M044038 GC02M044208 GC02M044014 GC02M043951 GC02M043893 GC02M043776 |
Summaries
for ABCG5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABCG5:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliaryexcretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene istandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene maycontribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ABCG5_HUMAN, Q9H222Function: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterolin and out of the enterocytes and in the selective sterol excretion by the liver into bile
Gene Wiki entry for ABCG5
|
Genomic Views
for ABCG5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABCG5 gene promoter:
HOXA9 SRF Bach2 SRF (504 AA) CUTL1 Evi-1 HEN1 AREB6 POU2F1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCG5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCG5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2p21ABCG5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M044039: view genomic region
(about GC identifiers)
Start:
|
44,039,611 bp from pter |
End:
|
44,066,004 bp from pter |
Size:
|
26,394 bases |
Orientation:
|
minus strand |
|
Proteins
for ABCG5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ABCG5_HUMAN, Q9H222 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family G member 5 Size: 651 amino acids; 72504 Da
Subunit: May form heterodimers with ABCG8 or be tightly coupled to ABCG8 along a pathway regulating diatery-sterolabsorption and excretion
Subcellular location: Membrane; Multi-pass membrane protein (Probable)Explore the universe of human proteins at neXtProt for ABCG5: NX_Q9H222
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H222
ABCG5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_071881.1
ENSEMBL proteins: ENSP00000260645 ENSP00000430935 ENSP00000384513 ENSP00000386501 ENSP00000445107 Reactome Protein details: Q9H222
Human Recombinant Protein Products for ABCG5:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
ABCG5 for ontologies About GeneDecksing
ABCG5 Antibody Products:
Assay Products for ABCG5: |
Protein
Domains /
Families
for ABCG5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCG5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H222ProtoNet protein and cluster: Q9H222 UniProtKB/Swiss-Prot: ABCG5_HUMAN, Q9H222Similarity: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204)subfamilySimilarity: Contains 1 ABC transmembrane type-2 domainSimilarity: Contains 1 ABC transporter domain |
Function
for ABCG5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ABCG5_HUMAN, Q9H222Function: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterolin and out of the enterocytes and in the selective sterol excretion by the liver into bile Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ABCG5 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ABCG5:
12 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Abcg5):
ABCG5 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Abcg5/Abcg8Abcg5/tm1Hobb for ABCG5
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ABCG5 (NM_022436) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCG5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCG5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCG5 |
|
Pathways & Interactions
for ABCG5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | Metabolism | | | 3 | Statin Pathway, Pharmacodynamics | | | 4 | Trafficking of dietary sterols | | | 5 | Nuclear receptors in lipid metabolism and toxicity | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for ABCG5
5/7 
Reactome Pathways for ABCG5 (see all 7)
1  PharmGKB Pathway for ABCG5
3 
Kegg Pathways (Kegg details for ABCG5):
ABCG5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABCG5
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
4 Interacting proteins for ABCG5 (Q9H2221, 2, 3 ENSP000002606454) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table
ABCG5 for ontologies About GeneDecksing
|
Drugs & Compounds
for ABCG5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ABCG5 for compounds About GeneDecksing
 Browse Tocris compounds for ABCG5
8 Novoseek chemical compound relationships for ABCG5 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sterol |
88.8 |
34 |
15044450 (3), 15860120 (2), 11452359 (2), 12208868 (2) (see all 23) |
| sitosterol |
84.3 |
2 |
15175352 (1), 12488046 (1) |
| ezetimibe |
75.4 |
1 |
19013286 (1) |
| cholesterol |
74.8 |
73 |
16614398 (5), 19019257 (4), 15175352 (3), 12679197 (3) (see all 35) |
| atp |
43.9 |
13 |
11668628 (2), 15980630 (1), 19846887 (1), 16614398 (1) (see all 10) |
| lipid |
32.9 |
6 |
15311998 (1), 15860120 (1), 17098593 (1), 16980816 (1) (see all 5) |
| phospholipid |
5.62 |
1 |
16250035 (1) |
| glucose |
0 |
1 |
17543849 (1) |
Search CenterWatch for drugs/clinical trials and news about ABCG5
|
Transcripts
for ABCG5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABCG5 gene: NM_022436.2 Unigene Cluster for ABCG5: ATP-binding cassette, sub-family G (WHITE), member 5 Hs.132992 [show with all ESTs]Unigene Representative Sequence: BC1115415 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000260645(uc002rtn.3) ENST00000486512 ENST00000405322(uc002rto.3 uc002rtp.3)
ENST00000409962 ENST00000543989(uc002rtm.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ABCG5 (NM_022436) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCG5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCG5 |
Additional cDNA sequence: AF312715.2 AF320293.1 AK091997.1 BC111541.1 BC111542.1 5 DOTS entries: DT.105305 DT.40281773 DT.99999805 DT.40188892 DT.97766428 18 AceView cDNA sequences: AF312715 AK091997 AF320293 AX747300 NM_022436 AI140253 BM856449 BX092855 AA700019 AI033358 AV695922 T99836 AV694671 T86384 AV689089 AA203458 T93792 T93842
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for ABCG5 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ABCG5
|
Expression
for ABCG5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCG5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGTTATTTG
About this image
See ABCG5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABCG5
SOURCE GeneReport for Unigene cluster: Hs.132992
UniProtKB/Swiss-Prot: ABCG5_HUMAN, Q9H222Tissue specificity: Strongly expressed in the liver, lower levels in the small intestine and colon
SABiosciences Custom PCR Arrays for ABCG5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCG5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCG5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCG5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCG5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCG5 |
Orthologs
for ABCG5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ABCG5 gene from 7/21 species (see all 21) About this table
ENSEMBL Gene Tree for ABCG5 (if available)
TreeFam Gene Tree for ABCG5 (if available) |
Paralogs
for ABCG5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABCG5 gene
- ABCG12 ABCA12 ABCA102 ABCA132 ABCA32 ABCA82 ABCG42 ABCA122
- ABCG82 ABCA42 ABCA72 ABCA22 ABCA92 ABCA62 ABCA52 ABCG22
11 SIMAP similar genes for ABCG5 using alignment to 9 protein entries: ABCG5_HUMAN (see all proteins):RHBDD3 NCF1 SYNE1 L3MBTL2 ETFA PAM16
NAA15 ABCG2 ADCY7 ABCG8 ABCG1
ABCG5 for paralogs About GeneDecksing
|
Genomic Variants
for ABCG5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCG5 (44039611 - 44066004 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ABCG5: --
Human Gene Mutation Database (HGMD): ABCG5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCG5 |
|
Disorders
/ Diseases
for ABCG5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCG5 for disorders About GeneDecksing
OMIM gene information: 605459
OMIM disorders: 210250
UniProtKB/Swiss-Prot: ABCG5_HUMAN, Q9H222
Defects in ABCG5 are a cause of sitosterolemia (STSL) [MIM:210250]; also known as phytosterolemia or shellfishsterolemia. It is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterolsincluding cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile.Sitosterolemia patients have hypercholesterolemia, very high levels of plant sterols in the plasma, and frequentlydevelop tendon and tuberous xanthomas, accelerated atherosclerosis and premature coronary artery disease
18  diseases for ABCG5: About MalaCardssitosterolemia macrothrombocytopenia hypercholesterolemia coronary heart disease
familial hypercholesterolemia tangier disease aortic atherosclerosis insulin resistance
cholelithiasis atherosclerosis thrombocytopenia twinning
alzheimer's disease colorectal cancer breast cancer hypertension
cholesterol hepatitis
2 diseases from the University of Copenhagen DISEASES database for ABCG5:Atherosclerosis Cholelithiasis 4 Novoseek disease relationships for ABCG5 gene About this table
Genetic Association Database (GAD): ABCG5
Human Genome Epidemiology (HuGE) Navigator: ABCG5 (45 documents)
Export disorders for ABCG5 gene to outside databases
|
Publications
for ABCG5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCG5 gene, integrated from 9 sources (see all 139):
(articles sorted by number of sources associating them with ABCG5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin- 2, encoded by ABCG5 and ABCG8, respectively. (PubMed id 11452359)1, 2, 3, 9 Lu K....Patel S.B. (2001)
- Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. (PubMed id 11099417)1, 2, 3 Berge K.E.... Hobbs H.H. (2000)
- Mutations in ATP-cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia. (PubMed id 11668628)1, 2, 9 Hubacek J.A.... Hobbs H.H. (2001)
- Polymorphisms in ABCG5 and ABCG8 transporters and plasma cholesterol levels. (PubMed id 15311998)1, 4, 9 Hubacek J.A....Poledne R. (2004)
- Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity. (PubMed id 15175352)1, 4, 9 Gylling H....Miettinen T.A. (2004)
- Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. (PubMed id 11138003)1, 2, 9 Lee M.-H.... Patel S.B. (2001)
- No genetic association between ATP binding cassette proteins and Japanese sporadic Alzheimer's disease. (PubMed id 15980630)1, 4, 9 Ohkubo T....Arai H. (2005)
- Role of ABCG1 and other ABCG family members in lipid metabolism. (PubMed id 11590207)1, 2, 9 Schmitz G.... Heimerl S. (2001)
- ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects. (PubMed id 15816807)1, 4, 9 Miwa K....Mabuchi H. (2005)
- ATP binding cassette G5 C1950G polymorphism may affect blood cholesterol concentrations in humans. (PubMed id 12220438)1, 4, 9 Weggemans R.M....Katan M.B. (2002)
|
External Searches for ABCG5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ABCG5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCG5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABCG5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ABCG5 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ABCG5 | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q9H222 |
|
| | |
About This Section
| Patent Information for ABCG5 gene:
Search GeneIP for patents involving ABCG5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ABCG5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ABCG5 | | OriGene shRNA RFP for ABCG5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCG5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCG5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABCG5 | | OriGene 3'-UTR Clone for ABCG5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCG5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABCG5 | | OriGene Custom Protein Services for ABCG5 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCG5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCG5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCG5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCG5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCG5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCG5 |
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