Aliases for ABCG4 Gene
External Ids for ABCG4 Gene
Previous GeneCards Identifiers for ABCG4 Gene
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. [provided by RefSeq, Jan 2017]
GeneCards Summary for ABCG4 Gene
ABCG4 (ATP Binding Cassette Subfamily G Member 4) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include protein homodimerization activity and ATPase activity. An important paralog of this gene is ABCG1.
UniProtKB/Swiss-Prot for ABCG4 Gene
May be involved in macrophage lipid homeostasis.