Aliases for ABCG4 Gene
Aliases for ABCG4 Gene
External Ids for ABCG4 Gene
- HGNC: 13884
- Entrez Gene: 64137
- Ensembl: ENSG00000172350
- OMIM: 607784
- UniProtKB: Q9H172
Previous GeneCards Identifiers for ABCG4 Gene
- GC11P135476
- GC11P120533
- GC11P119054
- GC11P118557
- GC11P118558
- GC11P118524
- GC11P119019
- GC11P114959
Summaries for ABCG4 Gene
-
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. [provided by RefSeq, Jan 2017]
GeneCards Summary for ABCG4 Gene
ABCG4 (ATP Binding Cassette Subfamily G Member 4) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include protein homodimerization activity and ATPase activity. An important paralog of this gene is ABCG1.
UniProtKB/Swiss-Prot for ABCG4 Gene
-
May be involved in macrophage lipid homeostasis.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABCG4 Gene
Genomics for ABCG4 Gene
Regulatory Elements for ABCG4 Gene
Enhancers for ABCG4 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ABCG4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ABCG4 gene promoter:
Regulatory Element Products
Genomic Location for ABCG4 Gene
- Chromosome:
- 11
- Start:
- 119,149,012 bp from pter
- End:
- 119,162,666 bp from pter
- Size:
- 13,655 bases
- Orientation:
- Plus strand
Genomic View for ABCG4 Gene
Genes around ABCG4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.3 by Ensembl
- 11q23.3 by Entrez Gene
- 11q23.3 by HGNC
ABCG4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ABCG4 Gene
Proteins for ABCG4 Gene
-
Protein details for ABCG4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H172-ABCG4_HUMAN
- Recommended name:
- ATP-binding cassette sub-family G member 4
- Protein Accession:
- Q9H172
- A8K1B5
- Q8WWH0
- Q8WWH1
- Q8WWH2
Protein attributes for ABCG4 Gene
- Size:
- 646 amino acids
- Molecular mass:
- 71896 Da
- Quaternary structure:
- No Data Available
Protein Expression for ABCG4 Gene
Post-translational modifications for ABCG4 Gene
Other Protein References for ABCG4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ABCG4
- Novus Biologicals Antibodies for ABCG4
-
Cloud-Clone Corp. Antibodies for ABCG4
- Invitrogen Antibodies for ABCG4
- antibodies-online Antibodies for ABCG4: See all 48
- GeneTex ABCG4 antibody for ABCG4
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ABCG4
- Origene Custom Protein Services for ABCG4
- Novus Biologicals proteins for ABCG4
-
Cloud-Clone Corp. Proteins for ABCG4
- Search GeneTex for Proteins for ABCG4
Assay Products
- antibodies-online Kits for ABCG4: See all 8
No data available for DME Specific Peptides for ABCG4 Gene
Domains & Families for ABCG4 Gene
Gene Families for ABCG4 Gene
- HGNC:
- IUPHAR :
Protein Domains for ABCG4 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ABCG4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H172UniProtKB/Swiss-Prot:
ABCG4_HUMAN :- Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
- Family:
-
- Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
Function for ABCG4 Gene
Molecular function for ABCG4 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in macrophage lipid homeostasis.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16870176 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016887 | ATPase activity | IEA | -- |
| GO:0017127 | cholesterol transporter activity | TAS | -- |
| GO:0034041 | sterol-transporting ATPase activity | IBA | -- |
Phenotypes for ABCG4 Gene
- MGI mutant phenotypes for ABCG4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ABCG4:
Animal Models for ABCG4 Gene
- MGI Knock Outs for ABCG4:
-
- Abcg4 tm1Dgen
Animal Model Products
-
Taconic Biosciences Mouse Models for ABCG4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ABCG4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ABCG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCG4 gene
- Search ViGene Biosciences for ABCG4
CRISPR Products
-
OriGene CRISPR knockouts for ABCG4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ABCG4
- GenScript: Design CRISPR guide RNA sequences for ABCG4
miRNA for ABCG4 Gene
- miRTarBase miRNAs that target ABCG4
miRNA Products
- Search ViGene Biosciences for ABCG4
Inhibitory RNA Products
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for ABCG4
- Browse OriGene Inhibitory RNA Products For ABCG4
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCG4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ABCG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ABCG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ABCG4
-
ViGene Biosciences adenoviral particle packaged cDNA for ABCG4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ABCG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCG4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ABCG4 Gene
Localization for ABCG4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ABCG4 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| peroxisome | 2 |
| endoplasmic reticulum | 2 |
| extracellular | 1 |
| endosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IBA,IEA | -- |
Pathways & Interactions for ABCG4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 |
.32
|
|
| 2 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||
Pathways by source for ABCG4 Gene
3 Reactome pathways for ABCG4 Gene
1 KEGG pathway for ABCG4 Gene
Interacting Proteins for ABCG4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0033344 | cholesterol efflux | TAS | 16682745 |
| GO:0055085 | transmembrane transport | TAS | -- |
No data available for SIGNOR curated interactions for ABCG4 Gene
Transcripts for ABCG4 Gene
mRNA/cDNA for ABCG4 Gene
- (6) REFSEQ mRNAs :
- (20) Additional mRNA sequences :
- (23) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ABCG4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ABCG4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ABCG4
- GenScript: Design CRISPR guide RNA sequences for ABCG4
miRNA Products
- Search ViGene Biosciences for ABCG4
Inhibitory RNA Products
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for ABCG4
- Browse OriGene Inhibitory RNA Products For ABCG4
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCG4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ABCG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ABCG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for ABCG4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
- Neural Tube (Nervous System)
- Liver (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for ABCG4 Gene
This gene is overexpressed in Brain - Cerebellum (x9.4), Brain - Cerebellar Hemisphere (x7.9), Brain - Cortex (x5.1), and Brain - Frontal Cortex (BA9) (x4.2).
This gene is overexpressed in Heart (31.4), Frontal cortex (20.4), and Adipocyte (17.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ABCG4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ABCG4 Gene:
ABCG4SOURCE GeneReport for Unigene cluster for ABCG4 Gene:
Hs.126378mRNA Expression by UniProt/SwissProt for ABCG4 Gene:
Q9H172-ABCG4_HUMAN
Tissue specificity:
Highly expressed in brain tissues with the exception of the spinal cord.
Evidence on tissue expression from TISSUES for ABCG4 Gene
- Nervous system(4.4)
- Lung(4.2)
- Liver(2.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for ABCG4
-
OriGene qPCR primer pairs for ABCG4
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ABCG4 Gene
Orthologs for ABCG4 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ABCG4 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ABCG4 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ABCG4 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Abcg4 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Abcg4 16 35 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ABCG4 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ABCG4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ABCG4 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ABCG4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | abcg4 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | abcg4a 35 |
|
OneToMany | |
| abcg4b 35 |
|
OneToMany | |||
| abcg4 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001858 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Atet 36 34 35 |
|
||
| BEST:CK02656 36 |
|
|
|||
| CG9663 36 35 |
|
||||
| CG5853 36 35 |
|
||||
| CG3164 35 |
|
ManyToMany | |||
| CG9664 35 |
|
ManyToMany | |||
| CG4822 36 35 |
|
||||
| CG9892 36 |
|
|
|||
| E23 36 35 |
|
||||
| CG31689 35 |
|
ManyToMany | |||
| w 36 35 |
|
||||
| CG32091 35 |
|
ManyToMany | |||
| CG17646 35 |
|
ManyToMany | |||
| st 36 35 |
|
||||
| worm (Caenorhabditis elegans) |
Secernentea | F02E11.1 36 |
|
|
|
| C05D10.3 36 |
|
|
|||
| C10C6.5 36 |
|
|
|||
| C16C10.12 36 |
|
|
|||
| F19B6.4 36 |
|
|
|||
| wht-4 35 |
|
ManyToMany | |||
| Y47D3A.11 36 |
|
|
|||
| T26A5.1 36 |
|
|
|||
| wht-2 35 |
|
ManyToMany | |||
| wht-8 35 |
|
ManyToMany | |||
| wht-3 35 |
|
ManyToMany | |||
| wht-6 35 |
|
ManyToMany | |||
| wht-5 35 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ADP1 35 |
|
OneToMany | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT4G27420 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os.7232 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.681 34 |
|
- Species where no ortholog for ABCG4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ABCG4 Gene
(5) SIMAP similar genes for ABCG4 Gene using alignment to 6 proteins:
Variants for ABCG4 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs193920956 | Uncertain significance | 119,150,202(+) | AAAAG(C/G/T)GGTAG | reference, missense, utr-variant-5-prime | |
| rs1000152386 | -- | 119,152,120(+) | GAAAG(A/G)CATAT | intron-variant, upstream-variant-2KB | |
| rs1000326400 | -- | 119,159,100(+) | CCCTA(G/T)GGATA | intron-variant | |
| rs1001093937 | -- | 119,148,942(+) | CCCCC(A/G)CGCCG | upstream-variant-2KB | |
| rs1001151479 | -- | 119,163,159(+) | CAGAG(G/T)CTTCA | downstream-variant-500B |
Residual Variation Intolerance Score:
11.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.03;
50.22% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ABCG4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ABCG4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABCG4 Gene
Disorders for ABCG4 Gene
Relevant External Links for ABCG4
No disorders were found for ABCG4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABCG4 Gene
Publications for ABCG4 Gene
- Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4. (PMID: 11856881) Annilo T. … Allikmets R. (Cytogenet. Cell Genet. 2001) 3 4 22 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PMID: 19343046) Saito A. … Kamatani N. (J. Hum. Genet. 2009) 3 46 64
- Integrative predictive model of coronary artery calcification in atherosclerosis. (PMID: 19948975) McGeachie M. … Ramoni M.F. (Circulation 2009) 3 46 64
- Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PMID: 18660489) Lu Y. … Boer J.M. (J. Lipid Res. 2008) 3 46 64
Products for ABCG4 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ABCG4
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ABCG4
- Origene Custom Protein Services for ABCG4
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ABCG4
- Browse OriGene Inhibitory RNA Products For ABCG4
- OriGene qPCR primer pairs and template standards for ABCG4
- OriGene qPCR primer pairs for ABCG4
- OriGene CRISPR knockouts for ABCG4
- OriGene ORF clones in human for ABCG4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ABCG4
- GenScript: Next-day shipping cDNA ORF clone for ABCG4 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ABCG4
- GenScript Custom Assay Services for ABCG4
- GenScript Custom overexpressing Cell Line Services for ABCG4
- GenScript: Design CRISPR guide RNA sequences for ABCG4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ABCG4
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ABCG4
- Novus Biologicals proteins for ABCG4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for ABCG4
- Cloud-Clone Corp. Proteins for ABCG4
- Browse Assay Kits at Cloud-Clone Corp.
- Taconic Biosciences Mouse Models for ABCG4
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for ABCG4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for ABCG4: See all 48
- antibodies-online Kits for ABCG4: See all 8
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex ABCG4 antibody for ABCG4
- Search GeneTex for Proteins for ABCG4
- ViGene Biosciences adenoviral particle packaged cDNA for ABCG4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ABCG4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ABCG4 gene
- Search ViGene Biosciences for ABCG4
- Horizon Cell Lines for ABCG4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ABCG4
- VectorBuilder custom plasmid, inducible vectors for ABCG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ABCG4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ABCG4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer