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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ABCF3 Gene

protein-coding   GIFtS: 53
GCID: GC03P183903

ATP-Binding Cassette, Sub-Family F (GCN20), Member 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ATP-Binding Cassette, Sub-Family F (GCN20), Member 31 2
EST2018642
ATP-Binding Cassette Sub-Family F Member 32
EC 3.6.38
EC 3.6.3.178

External Ids:    HGNC: 721   Entrez Gene: 553242   Ensembl: ENSG000001612047   UniProtKB: Q9NUQ83   

Export aliases for ABCF3 gene to outside databases

Previous GC identifers: GC03U990120 GC03P185305 GC03P185224 GC03P185386 GC03P181310


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ABCF3 Gene: 
ABCF3 (ATP-binding cassette, sub-family F (GCN20), member 3) is a protein-coding gene. Diseases associated with ABCF3 include west nile virus, and major depressive disorder. GO annotations related to this gene include ATPase activity and ATP binding. An important paralog of this gene is ABCF1.

UniProtKB/Swiss-Prot: ABCF3_HUMAN, Q9NUQ8
Function: Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ABCF3 gene promoter:
         E2F-3a   E2F-4   E2F-5   Lmo2   E2F-2   FAC1   E2F   E2F-1   Sox9   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABCF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ABCF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q27.1   Ensembl cytogenetic band:  3q27.1   HGNC cytogenetic band: 3q27.1

ABCF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABCF3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P183903:  view genomic region     (about GC identifiers)

Start:
183,903,811 bp from pter      End:
183,911,800 bp from pter
Size:
7,990 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ABCF3_HUMAN, Q9NUQ8 (See protein sequence)
Recommended Name: ATP-binding cassette sub-family F member 3  
Size: 709 amino acids; 79745 Da
Caution: Lacks transmembrane domains and is probably not involved in transport
Sequence caution: Sequence=BAB14989.1; Type=Erroneous initiation;
Secondary accessions: A8K241 Q86UA2 Q8NAN1 Q96GS8 Q9H7A8
Alternative splicing: 2 isoforms:  Q9NUQ8-1   Q9NUQ8-2   

Explore the universe of human proteins at neXtProt for ABCF3: NX_Q9NUQ8

Explore proteomics data for ABCF3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NUQ8

  • 3 DME Specific Peptides for ABCF3 (Q9NUQ8)
     NGAGKST  LLLLDEP  GENGAGKST 

    ABCF3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ABCF3 Protein Expression
    REFSEQ proteins: NP_060828.2  
    ENSEMBL proteins: 
     ENSP00000411471   ENSP00000415704   ENSP00000292808  

    Human Recombinant Protein Products for ABCF3: 
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    OriGene Purified Protein for ABCF3
    OriGene Protein Over-expression Lysate for ABCF3
    OriGene MassSpec for ABCF3 
    OriGene Custom Protein Services for ABCF3
    GenScript Custom Purified and Recombinant Proteins Services for ABCF3
    Novus Biologicals ABCF3 Protein
    Novus Biologicals ABCF3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ABCF3 


    ABCF3 Antibody Products: 
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    ThermoFisher Antibody for ABCF3
    LSBio Antibodies in human, mouse, rat for ABCF3 

    Assay Products for ABCF3: 
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    Cloud-Clone Corp. ELISAs for ABCF3 
    Cloud-Clone Corp. CLIAs for ABCF3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ABCF: ATP binding cassette transporters / subfamily F

    4 InterPro protein domains:
     IPR003439 ABC_transporter-like
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase
     IPR017871 ABC_transporter_CS

    Graphical View of Domain Structure for InterPro Entry Q9NUQ8

    ProtoNet protein and cluster: Q9NUQ8

    UniProtKB/Swiss-Prot: ABCF3_HUMAN, Q9NUQ8
    Similarity: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily
    Similarity: Contains 2 ABC transporter domains


    ABCF3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABCF3_HUMAN, Q9NUQ8
    Function: Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B
    (By similarity)

         Genatlas biochemistry entry for ABCF3:
    ATP-binding cassette superfamily,subfamily F (GCN20),member 3

         Enzyme Numbers (IUBMB): EC 3.6.32 EC 3.6.3.172

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity IEA--
    GO:0017111nucleoside-triphosphatase activity ----
         
    ABCF3 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Abcf3 (no phenotypes)

    ABCF3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Abcf3tm1Lex for ABCF3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ABCF3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ABCF3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ABCF3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ABCF3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABCF3
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ABCF3:
    hsa-miR-4271 hsa-miR-625 hsa-miR-32* hsa-miR-1910 hsa-miR-455-3p
    SwitchGear 3'UTR luciferase reporter plasmidABCF3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ABCF3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCF3

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of ABCF3

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ABCF3 (see all 7)
    OriGene ORF clones in mouse, rat for ABCF3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ABCF3 (NM_018358)
    Sino Biological Human cDNA Clone for ABCF3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABCF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCF3
    Sirion Biotech Customized lentivirus for stable overexpression of ABCF3 
                         Customized lentivirus expression plasmids for stable overexpression of ABCF3 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for ABCF3
    Search LifeMap BioReagents cell lines for ABCF3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCF3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABCF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/888 Interacting proteins for ABCF3 (Q9NUQ82, 3 ENSP000004114714) via UniProtKB, MINT, STRING, and/or I2D (see all 888)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051607defense response to virus IEA--

    ABCF3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ABCF3

    Search CenterWatch for drugs/clinical trials and news about ABCF3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ABCF3 gene: 
    NM_018358.2  

    Unigene Cluster for ABCF3:

    ATP-binding cassette, sub-family F (GCN20), member 3
    Hs.361323  [show with all ESTs]
    Unigene Representative Sequence: AK097073
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000429586(uc003fmz.2 uc003fna.2 uc003fnb.2) ENST00000421340
    ENST00000485921 ENST00000463685 ENST00000478288 ENST00000292808 ENST00000473311
    ENST00000481116 ENST00000498136 ENST00000466416 ENST00000471226 ENST00000472608
    ENST00000475728 ENST00000489719 ENST00000468892 ENST00000466742 ENST00000480562
    ENST00000480539
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ABCF3
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ABCF3:
    hsa-miR-4271 hsa-miR-625 hsa-miR-32* hsa-miR-1910 hsa-miR-455-3p
    SwitchGear 3'UTR luciferase reporter plasmidABCF3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ABCF3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCF3
    Clone
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    OriGene clones in human, mouse for ABCF3 (see all 7)
    OriGene ORF clones in mouse, rat for ABCF3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ABCF3 (NM_018358)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABCF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCF3
    Sirion Biotech Customized lentivirus for stable overexpression of ABCF3 
                         Customized lentivirus expression plasmids for stable overexpression of ABCF3 
    Primer
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    OriGene qPCR primer pairs and template standards for ABCF3
    OriGene qSTAR qPCR primer pairs in human, mouse for ABCF3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCF3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCF3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCF3

    Additional mRNA sequence: 

    AK002060.1 AK024758.1 AK027288.1 AK092415.1 AK097073.1 AK126150.1 AK290106.1 AK299256.1 
    AK299433.1 BC009253.2 BC035652.1 BC051754.2 BC051884.1 U66685.1 

    24/26 DOTS entries (see all 26):

    DT.454980  DT.95108652  DT.95081940  DT.120902378  DT.95093818  DT.101978221  DT.92041725  DT.100813236 
    DT.100813243  DT.100028670  DT.100680191  DT.101973577  DT.91921330  DT.100813240  DT.95200399  DT.120902361 
    DT.120902384  DT.91821276  DT.120902373  DT.120902379  DT.120902369  DT.120902383  DT.86846368  DT.95086095 

    24/296 AceView cDNA sequences (see all 296):

    BU527515 BI819233 BM544115 BC051754 AL706281 CR616374 CR607850 BE268250 
    BC009253 BX411388 AK024758 AL563529 BQ228746 T30711 BQ212205 AA281173 
    BU077626 BI754618 BE397105 BU173353 BQ054758 BC035652 AK097073 BQ898068 

    GeneLoc Exon Structure

    5/20 Alternative Splicing Database (ASD) splice patterns (SP) for ABCF3 (see all 20)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^
    SP1:                                                  -     -           -     -                                                                                 
    SP2:                                      -           -     -           -     -                                                                                 
    SP3:                                                  -     -                                                                                                   
    SP4:                                                                                                                                                            
    SP5:                                                  -                 -     -                                                                                 

    ExUns: 14a · 14b · 14c · 14d ^ 15a · 15b · 15c ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b
    SP1:                          -           -                                                         
    SP2:                          -           -                                                         
    SP3:                          -           -                                                         
    SP4:                          -           -                                                         
    SP5:                                                                                                


    ECgene alternative splicing isoforms for ABCF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ABCF3 expression in normal human tissues (normalized intensities)      ABCF3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGGCCACCA
    ABCF3 Expression
    About this image


    ABCF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)
             oocyte   
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Head Mesenchyme (Muscoskeletal System)
             Head Mesenchyme
     
     Oral Cavity (Gastrointestinal Tract)
             mouth   
     
     Limb (Muscoskeletal System)

    See ABCF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ABCF3

    SOURCE GeneReport for Unigene cluster: Hs.361323
        SABiosciences Custom PCR Arrays for ABCF3
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCF3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ABCF3 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Abcf31 , 5 ATP-binding cassette, sub-family F (GCN20), member 3 less1, 5 88.34(n)1
    96.9(a)1
      16 (12.46 cM)5
    274061  NM_013852.21  NP_038880.11 
     205485775 
    chicken
    (Gallus gallus)
    Aves ABCF31 ATP-binding cassette, sub-family F (GCN20), member 3 less 76.45(n)
    83.36(a)
      424950  XM_422757.3  XP_422757.2 
    lizard
    (Anolis carolinensis)
    Reptilia ABCF36
    Uncharacterized protein
    81(a)
    1 ↔ 1
    GL343245.1(767337-789124)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3985652 hypothetical protein LOC398565 72.99(n)    BC046370.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003312271 ATP-binding cassette sub-family F member 3-like 74.82(n)
    78.1(a)
      100331227  XM_002667473.2  XP_002667519.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG93301 CG9330 59.62(n)
    57.74(a)
      40131  NM_140872.2  NP_649129.1 
    worm
    (Caenorhabditis elegans)
    Secernentea abcf-31 Protein ABCF-3 53.35(n)
    51.6(a)
      175873  NM_065938.4  NP_498339.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GCN20(YFR009W)4
    GCN201
    Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA less4
    Gcn20p1
    49.98(n)1
    46.45(a)1
      6(162488-164746)4
    8505611, 4  NP_116664.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons GCN31 ABC transporter F family member 3 49.9(n)
    43.38(a)
      842763  NM_105130.3  NP_176636.1 
    rice
    (Oryza sativa)
    Liliopsida Os.107582 Oryza sativa (japonica cultivar-group) cDNA cloneJ023121N24, full insert sequence less 72.58(n)    AK099841.1 


    ENSEMBL Gene Tree for ABCF3 (if available)
    TreeFam Gene Tree for ABCF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ABCF3 gene
    ABCF12  
    2 SIMAP similar genes for ABCF3 using alignment to 2 protein entries:     ABCF3_HUMAN (see all proteins):
    ABCF1    ABCF2

    ABCF3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/403 SNPs in ABCF3 are shown (see all 403)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1438522741,2
    Cuntested1183907655(+) TTGACC/TGGTTT 2 R W mis11Minor allele frequency- T:0.00NA 4552
    rs665784041,2
    C--183902703(+) AAATT-/AAAAAA 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs2021920361,2
    C--183902720(+) AAAAAA/GAATAT 1 -- us2k10--------
    rs64439541,2
    C,F,A,H--183902801(+) CCAGTC/TTGTGT 1 -- us2k127Minor allele frequency- T:0.44EA NS NA WA CSA 2273
    rs1859074691,2
    --183903020(+) ATGGTG/TCAATA 1 -- us2k10--------
    rs1509359641,2
    --183903203(+) AATAGC/TCTTTT 1 -- us2k10--------
    rs1908286901,2
    --183903284(+) GTCCTG/TGTTTT 1 -- us2k10--------
    rs1407562831,2
    C--183903518(+) AGCTCA/TGGGCA 1 -- us2k10--------
    rs1824245081,2
    --183903520(+) CTCTGC/GGCAGG 1 -- us2k10--------
    rs1501154221,2
    C--183903541(+) GGCCTA/GACTGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ABCF3 (183903811 - 183911800 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ABCF3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv829812CNV Loss17160897
    nsv878057CNV Loss21882294
    nsv878056CNV Loss21882294
    nsv878058CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for ABCF3:    About MalaCards
    west nile virus    major depressive disorder    tuberculosis


    ABCF3 for disorders           About GeneDecksing


    Export disorders for ABCF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ABCF3 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with ABCF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1, 3 Allikmets R....Dean M. (1996)
    4. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. A mega-analysis of genome-wide association studies for major depressive disorder. (PubMed id 22472876)1 (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55324 HGNC: 72 AceView: ABCF3 Ensembl:ENSG00000161204 euGenes: HUgn55324
    ECgene: ABCF3 H-InvDB: ABCF3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ABCF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ABCF3 gene:
    Search GeneIP for patents involving ABCF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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