Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ABCF3 Gene

Aliases for ABCF3 Gene

  • ATP-Binding Cassette, Sub-Family F (GCN20), Member 3 2 3
  • ATP-Binding Cassette Sub-Family F Member 3 3
  • EC 3.6.3.17 63
  • EST201864 3
  • EC 3.6.3 63

External Ids for ABCF3 Gene

Previous GeneCards Identifiers for ABCF3 Gene

  • GC03U990120
  • GC03P185305
  • GC03P185224
  • GC03P185386
  • GC03P183903
  • GC03P181310

Summaries for ABCF3 Gene

GeneCards Summary for ABCF3 Gene

ABCF3 (ATP-Binding Cassette, Sub-Family F (GCN20), Member 3) is a Protein Coding gene. GO annotations related to this gene include ATPase activity. An important paralog of this gene is ABCF1.

UniProtKB/Swiss-Prot for ABCF3 Gene

  • Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABCF3 Gene

Genomics for ABCF3 Gene

Regulatory Elements for ABCF3 Gene

Genomic Location for ABCF3 Gene

Start:
184,186,023 bp from pter
End:
184,194,012 bp from pter
Size:
7,990 bases
Orientation:
Plus strand

Genomic View for ABCF3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ABCF3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABCF3 Gene

Proteins for ABCF3 Gene

  • Protein details for ABCF3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NUQ8-ABCF3_HUMAN
    Recommended name:
    ATP-binding cassette sub-family F member 3
    Protein Accession:
    Q9NUQ8
    Secondary Accessions:
    • A8K241
    • Q86UA2
    • Q8NAN1
    • Q96GS8
    • Q9H7A8

    Protein attributes for ABCF3 Gene

    Size:
    709 amino acids
    Molecular mass:
    79745 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14989.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ABCF3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABCF3 Gene

Proteomics data for ABCF3 Gene at MOPED

Selected DME Specific Peptides for ABCF3 Gene

Post-translational modifications for ABCF3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ABCF3 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains for ABCF3 Gene

Gene Families for ABCF3 Gene

HGNC:
  • ABCF :ATP binding cassette transporters / subfamily F

Protein Domains for ABCF3 Gene

Suggested Antigen Peptide Sequences for ABCF3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NUQ8

UniProtKB/Swiss-Prot:

ABCF3_HUMAN :
  • Q9NUQ8
Domain:
  • Contains 2 ABC transporter domains.
Family:
  • Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
genes like me logo Genes that share domains with ABCF3: view

Function for ABCF3 Gene

Molecular function for ABCF3 Gene

GENATLAS Biochemistry: ATP-binding cassette superfamily,subfamily F (GCN20),member 3
UniProtKB/Swiss-Prot Function: Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.

Enzyme Numbers (IUBMB) for ABCF3 Gene

Gene Ontology (GO) - Molecular Function for ABCF3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
GO:0005524 ATP binding IEA --
GO:0016887 ATPase activity IEA --
genes like me logo Genes that share ontologies with ABCF3: view

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ABCF3 Gene

Localization for ABCF3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ABCF3 Gene COMPARTMENTS Subcellular localization image for ABCF3 gene
Compartment Confidence
cytosol 3
nucleus 2
endosome 1

Gene Ontology (GO) - Cellular Components for ABCF3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with ABCF3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ABCF3 Gene

Pathways for ABCF3 Gene

SuperPathways for ABCF3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ABCF3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006200 obsolete ATP catabolic process --
GO:0008152 metabolic process IEA --
GO:0051607 defense response to virus IEA --
genes like me logo Genes that share ontologies with ABCF3: view

No data available for Pathways by source for ABCF3 Gene

Transcripts for ABCF3 Gene

Unigene Clusters for ABCF3 Gene

ATP-binding cassette, sub-family F (GCN20), member 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ABCF3 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^
SP1: - - - -
SP2: - - - - -
SP3: - -
SP4:
SP5: - - -
SP6: - - - -
SP7: - - - - -
SP8: - - - - -
SP9: - - -
SP10:
SP11:
SP12: - - - - - -
SP13: - -
SP14: -
SP15: - - -
SP16: - - - - - - - - - -
SP17:
SP18:
SP19:
SP20:

ExUns: 14a · 14b · 14c · 14d ^ 15a · 15b · 15c ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b
SP1: - -
SP2: - -
SP3: - -
SP4: - -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20: -

Relevant External Links for ABCF3 Gene

GeneLoc Exon Structure for
ABCF3
ECgene alternative splicing isoforms for
ABCF3

Expression for ABCF3 Gene

mRNA expression in normal human tissues for ABCF3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ABCF3 Gene

SOURCE GeneReport for Unigene cluster for ABCF3 Gene Hs.361323

genes like me logo Genes that share expressions with ABCF3: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABCF3 Gene

Orthologs for ABCF3 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABCF3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ABCF3 35
  • 99.72 (n)
  • 99.72 (a)
ABCF3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ABCF3 35
  • 91.77 (n)
  • 98.31 (a)
ABCF3 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ABCF3 35
  • 92.67 (n)
  • 98.31 (a)
ABCF3 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Abcf3 35
  • 88.34 (n)
  • 96.9 (a)
Abcf3 16
Abcf3 36
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ABCF3 36
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ABCF3 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Abcf3 35
  • 88.53 (n)
  • 96.33 (a)
chicken
(Gallus gallus)
Aves ABCF3 35
  • 76.45 (n)
  • 83.36 (a)
ABCF3 36
  • 82 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ABCF3 36
  • 81 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia LOC398565 35
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100145696 35
  • 70.29 (n)
  • 77.86 (a)
zebrafish
(Danio rerio)
Actinopterygii ABCF3 36
  • 76 (a)
OneToOne
LOC100331227 35
  • 74.37 (n)
  • 77.26 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012005 35
  • 60.88 (n)
  • 58.39 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9330 35
  • 59.62 (n)
  • 57.74 (a)
CG9330 36
  • 56 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea abcf-3 35
  • 53.4 (n)
  • 51.9 (a)
abcf-3 36
  • 49 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AEL032W 35
  • 51.41 (n)
  • 47.95 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GCN20 35
  • 51.27 (n)
  • 47.8 (a)
GCN20 36
  • 41 (a)
OneToMany
GCN20 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0A10857g 35
  • 49.53 (n)
  • 47.44 (a)
soybean
(Glycine max)
eudicotyledons Gma.4290 35
thale cress
(Arabidopsis thaliana)
eudicotyledons GCN3 35
  • 49.98 (n)
  • 43.02 (a)
corn
(Zea mays)
Liliopsida Zm.4768 35
rice
(Oryza sativa)
Liliopsida Os.10758 35
bread mold
(Neurospora crassa)
Ascomycetes NCU04051 35
  • 53.88 (n)
  • 48.85 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC29A3.09c 35
  • 50.22 (n)
  • 47.34 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.11475 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1523 36
  • 57 (a)
OneToOne
Species with no ortholog for ABCF3:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ABCF3 Gene

ENSEMBL:
Gene Tree for ABCF3 (if available)
TreeFam:
Gene Tree for ABCF3 (if available)

Paralogs for ABCF3 Gene

Paralogs for ABCF3 Gene

Selected SIMAP similar genes for ABCF3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ABCF3: view

Variants for ABCF3 Gene

Sequence variations from dbSNP and Humsavar for ABCF3 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs843337 -- 184,194,437(-) GATGG(C/T)TTCTC downstream-variant-500B
rs843338 -- 184,193,677(-) CGGCG(A/G)AACTG reference, synonymous-codon
rs843339 -- 184,191,375(-) AGCCC(A/G)GGCCC intron-variant
rs843342 -- 184,190,214(-) AAGAC(A/G)CCAGG intron-variant
rs843343 -- 184,190,114(-) TGCCA(C/T)GTGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ABCF3 Gene

Variant ID Type Subtype PubMed ID
nsv829812 CNV Loss 17160897
nsv878056 CNV Loss 21882294
nsv878057 CNV Loss 21882294
nsv878058 CNV Gain 21882294

Relevant External Links for ABCF3 Gene

HapMap Linkage Disequilibrium report
ABCF3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABCF3 Gene

Disorders for ABCF3 Gene

No disorders were found for ABCF3 Gene.

No data available for UniProtKB/Swiss-Prot for ABCF3 Gene

Publications for ABCF3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PMID: 8894702) Allikmets R. … Dean M. (Hum. Mol. Genet. 1996) 2 3
  4. The human ATP-binding cassette (ABC) transporter superfamily. (PMID: 11435397) Dean M. … Allikmets R. (Genome Res. 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ABCF3 Gene

Sources for ABCF3 Gene

Back to Top

Content