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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ABCF1 Gene

protein-coding   GIFtS: 55
GCID: GC06P030539

ATP-binding cassette, sub-family F (GCN20), member 1


(Previous symbol: ABC50)
 Explore 14 diseases affiliated with
ABCF1 via our new
 Human Malady Compendium 
Biological research products
for ABCF1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ATP-Binding Cassette, Sub-Family F (GCN20), Member 11 2     ATP-Binding Cassette Sub-Family F Member 12
ABC501 2 3 5     TNFalpha-Inducible ATP-Binding Protein2
TNF-Alpha-Stimulated ABC Protein2 3     ATP-Binding Cassette 503
EST1231471     EC 2.7.7.68
ABC272     EC 3.6.3.178
ATP-Binding Cassette 50 (TNF-Alpha Stimulated)2     

External Ids:    HGNC: 701   Entrez Gene: 232   Ensembl: ENSG000002045747   OMIM: 6034295   UniProtKB: Q8NE713   

Export aliases for ABCF1 gene to outside databases

Previous GC identifers: GC06P030594 GC06P030309 GC06P030645 GC06P030647 GC06P030339


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ABCF1:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC
proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven
distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily.
Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most
ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of
protein synthesis and the inflammation process. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ABCF1_HUMAN, Q8NE71
Function: Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not
involved in the ribosome biogenesis

Gene Wiki entry for ABCF1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167245.1  NT_167246.1  NT_167247.1  NT_167248.1  
NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ABCF1 gene promoter:
         AREB6   IRF-2   p53   SREBP-1a   Pax-5   SREBP-1c   SREBP-1b   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ABCF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ABCF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.33   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.33

ABCF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABCF1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030539:  view genomic region     (about GC identifiers)

Start:
30,539,153 bp from pter      End:
30,564,956 bp from pter
Size:
25,804 bases      Orientation:
plus strand

6 alternative locations:
Chr6+,ALT_REF_LOCI_4 30,506,901-30,527,040      Chr6+,ALT_REF_LOCI_6 30,528,662-30,584,395      Chr6+,ALT_REF_LOCI_3 30,529,391-30,560,585     
Chr6+,ALT_REF_LOCI_5 30,532,447-30,552,586      Chr6+,ALT_REF_LOCI_2 30,529,000-30,588,340      Chr6+,ALT_REF_LOCI_7 30,460,913-30,481,051     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ABCF1_HUMAN, Q8NE71 (See protein sequence)
Recommended Name: ATP-binding cassette sub-family F member 1  
Size: 845 amino acids; 95926 Da
Subunit: Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status.
Isoform 2 associates (via both ABC transporter domains) with the ribosomes
Subcellular location: Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope
Secondary accessions: A2BF75 O14897 Q69YP6
Alternative splicing: 2 isoforms:  Q8NE71-1   Q8NE71-2   

Explore the universe of human proteins at neXtProt for ABCF1: NX_Q8NE71

Post-translational modifications:

  • Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by
  • CK2; inhibits association of EIF2 with ribosomes1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8NE71

  • 3 DME Specific Peptides for ABCF1 (Q8NE71)
     LMLDEPT  LILDEPT  KRLKLLE 

    ABCF1 Protein expression data from MOPED and PaxDb:    About this image 
    ABCF1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001020262.1  NP_001081.1  

    ENSEMBL proteins: 
     ENSP00000313603   ENSP00000365728   ENSP00000405512   ENSP00000440893   ENSP00000379772  
     ENSP00000445100  

    Human Recombinant Protein Products for ABCF1: 
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    Novus Biologicals ABCF1 Protein
    Novus Biologicals ABCF1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ABCF1

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IEA--
    GO:0005654nucleoplasm IEA--
    GO:0005737cytoplasm IDA19570978
    GO:0005840ribosome IEA--
    GO:0042788polysomal ribosome IDA19570978

    ABCF1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ABCF1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ABCF1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR003439 ABC_transporter-like
     IPR003593 AAA+_ATPase
     IPR017871 ABC_transporter_CS

    Graphical View of Domain Structure for InterPro Entry Q8NE71

    ProtoNet protein and cluster: Q8NE71

    UniProtKB/Swiss-Prot: ABCF1_HUMAN, Q8NE71
    Similarity: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily
    Similarity: Contains 2 ABC transporter domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABCF1_HUMAN, Q8NE71
    Function: Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not
    involved in the ribosome biogenesis
    Induction: By TNF in cultured synoviocytes

         Genatlas biochemistry entry for ABCF1:
    ATP binding cassette superfamily,subfamily F (GCN20) member 1,widely expressed,putative ribosomal protein,involved in
    translation of mRNA,present in synoviocytes after TNFA induction,potentially involved in inflammatory process

         Enzyme Numbers (IUBMB): EC 2.7.7.62 EC 3.6.3.172

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17894550
    GO:0005524ATP binding IEA--
    GO:0008135translation factor activity, nucleic acid binding TAS9790762
    GO:0008494translation activator activity IDA19570978
    GO:0016887ATPase activity IEA--
         
    ABCF1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ABCF1 

    miRNA
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    hsa-miR-4291 hsa-miR-15a hsa-miR-497 hsa-miR-103a hsa-miR-424 hsa-miR-593* hsa-miR-16 hsa-miR-195
    SwitchGear 3'UTR luciferase reporter plasmidABCF1 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCF1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABCF1

    5/746 Interacting proteins for ABCF1 (Q8NE712, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 746)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABCF3Q9NUQ82MINT-7945693 MINT-7947479
    ACTBP607092MINT-7945693 MINT-7947479
    ACTL6AO960192MINT-7945693 MINT-7947479
    ACTR1AP611632MINT-7945693 MINT-7947479
    ACTR2P611602MINT-7945693 MINT-7947479
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation TAS9790762
    GO:0006413translational initiation IMP19570978
    GO:0006954inflammatory response TAS9790762
    GO:0042254NOT ribosome biogenesis IDA19570978
    GO:0045727positive regulation of translation IDA19570978

    ABCF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ABCF1

    1 HMDB Compound for ABCF1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Search CenterWatch for drugs/clinical trials and news about ABCF1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ABCF1 gene (2 alternative transcripts): 
    NM_001025091.1  NM_001090.2  

    Unigene Cluster for ABCF1:

    ATP-binding cassette, sub-family F (GCN20), member 1
    Hs.655285  [show with all ESTs]
    Unigene Representative Sequence: NM_001025091
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326195(uc003nqk.2 uc003nql.3 uc003nqm.3) ENST00000376545
    ENST00000441867 ENST00000468958 ENST00000396515 ENST00000542772 ENST00000475993
    ENST00000479542

    miRNA
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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate ABCF1 (see all 10):
    hsa-miR-4291 hsa-miR-15a hsa-miR-497 hsa-miR-103a hsa-miR-424 hsa-miR-593* hsa-miR-16 hsa-miR-195
    SwitchGear 3'UTR luciferase reporter plasmidABCF1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCF1 (see all 7)
    OriGene shRNA RFP: ABCF1
    OriGene siRNA: ABCF1
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    Sirion Biotech Custom design and validation of potent shRNA sequences against ABCF1 
    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCF1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCF1 (see all 2)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ABCF1 (NM_001090)
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    Primer
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    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCF1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCF1
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    Additional cDNA sequence: 

    AB209564.1 AF027302.1 AF075071.1 AK298061.1 AK307551.1 AL832430.1 BC016772.1 BC034488.2 
    BC112923.1 U66677.1 

    18 DOTS entries:

    DT.100815058  DT.101984925  DT.217889  DT.92442036  DT.100815063  DT.95108905  DT.121360162  DT.97769090 
    DT.100815055  DT.95258527  DT.91777805  DT.100815060  DT.121360120  DT.121360366  DT.95189966  DT.97855263 
    DT.40190068  DT.95189965 

    24/391 AceView cDNA sequences (see all 391):

    AW474795 BQ060931 AA593333 AA663990 BM008717 BQ060751 BM476604 BM666238 
    AI281821 BQ065050 BQ073631 AW250881 AI282663 AL832430 BQ898945 AL040535 
    BQ958085 CK003422 BE047866 BQ645169 AA486482 AI862783 BQ001284 AI684204 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ABCF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGGTGGAGT
    ABCF1 Expression
    About this image
    See ABCF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ABCF1

    SOURCE GeneReport for Unigene cluster: Hs.655285

    UniProtKB/Swiss-Prot: ABCF1_HUMAN, Q8NE71
    Tissue specificity: Ubiquitous

        SABiosciences Expression via Pathway-Focused PCR Array including ABCF1: 
              Drug Transporters in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for ABCF1 gene from 8/30 species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia ABCF16
    --
    80(a)
    1 ↔ 1
    2(191965325-192012930)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU914504.12   -- 76.69(n)    BU914504.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CK236499.12   -- 76.56(n)    CK236499.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG17031 , 3 ATP-binding cassette (ABC) transporter3
    CG17031
    65(a)3
    58.49(n)1
    55.42(a)1
      10D13
    321121  NM_132508.31  NP_572736.11 
    worm
    (Caenorhabditis elegans)
    Secernentea F18E2.23
    abcf-11
    ABC transpoter3
    Protein ABCF-11
    61(a)3
    58.23(n)1
    60.78(a)1
      V(12763786-12765958)3
    1797481  NM_073791.41  NP_506192.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons GCN41 ABC transporter F family member 4 51.68(n)
    47.86(a)
      824619  NM_115311.3  NP_567001.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g04415001 hypothetical protein 52.55(n)
    45.39(a)
      4333216  NM_001056996.1  NP_001050461.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria yheS6
    fused predicted transporter subunits of ABC superf...
    28(a)
    1 → many
    Chromosome(3479311-3481224)


    ENSEMBL Gene Tree for ABCF1 (if available)
    TreeFam Gene Tree for ABCF1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ABCF1 gene
    ABCF32  
    3 SIMAP similar genes for ABCF1 using alignment to 10 protein entries:     ABCF1_HUMAN (see all proteins):
    ABCF3    ABCB4    ABCF2

    ABCF1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/372 NCBI SNPs in ABCF1 are shown (see all 372    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs31302421,2
    C,F,H--30537339(+) CACTCA/GTGCCA 2 -- us2k124Minor allele frequency- G:0.25NS EA NA WA CSA 2352
    rs759298141,2
    F--30537345(+) TGCCAC/GTCCAG 2 -- us2k11Minor allele frequency- G:0.05EA 120
    rs1908263691,2
    --30537391(+) TGTCCA/GAACAC 2 -- us2k10--------
    rs774165961,2
    --30537489(+) AATGAT/CTTGCT 2 -- us2k13Minor allele frequency- C:0.08CSA WA EA 240
    rs1148476971,2
    F--30537516(+) GAGGCC/TTCATT 2 -- us2k11Minor allele frequency- T:0.04WA 118
    rs31326131,2
    C,F,O,A,H--30537606(-) GATTAC/GGTTTC 2 -- us2k120Minor allele frequency- N:0.00EA NS NA WA CSA 950
    rs678927101,2
    C--30537612(+) TAATC-/AGAGATC 2 -- us2k10--------
    rs31302431,2
    C,F,A,H--30537853(+) acaggA/Ctttag 2 -- us2k124Minor allele frequency- C:0.29NS EA NA WA CSA 2352
    rs1394270971,2
    --30537999(+) GAATCA/TTCATT 2 -- us2k10--------
    rs95010231,2
    C,F,H--30538193(+) CTATCA/GAACAT 2 -- us2k16Minor allele frequency- G:0.02NS EA MN WA 632

    HapMap Linkage Disequilibrium report for ABCF1 (30539153 - 30564956 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ABCF1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ABCF1 for disorders           About GeneDecksing

    OMIM gene information: 603429    OMIM disorders: --

    14 diseases for ABCF1:    About MalaCards
    systemic lupus erythematosus    eosinophilic esophagitis    lupus erythematosus    chronic lymphocytic leukemia
    lymphocytic leukemia    autoimmune pancreatitis    leukemia    lung cancer
    pancreatitis    pneumonia    esophagitis    tuberculosis
    malaria    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: ABCF1 (7 documents)

    Export disorders for ABCF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ABCF1 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with ABCF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes. (PubMed id 9790762)1, 2, 3 Richard M.... Beaulieu A.D. (1998)
    2. The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2. (PubMed id 17894550)1, 2, 9 Paytubi S....Proud C.G. (2008)
    3. ABC50 promotes translation initiation in mammalian ce lls. (PubMed id 19570978)1, 2 Paytubi S....Proud C.G. (2009)
    4. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (2007)
    5. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    9. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23 HGNC: 70 AceView: ABCF1 Ensembl:ENSG00000204574 euGenes: HUgn23
    ECgene: ABCF1 H-InvDB: ABCF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ABCF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ABCF1 Genetics and Cytogenetics in Oncology and Haematology
    ABCMdbhttp://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q8NE71

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ABCF1 gene:
    Search GeneIP for patents involving ABCF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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