ABCE1 Gene
protein-coding GIFtS: 53
GCID: GC04P146019
|
|
ATP-binding cassette, sub-family E (OABP), member 1 (Previous symbols: RNASEL1, RNASELI, RNS4I)
| |
Aliases for ABCE1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family E (OABP), Member 11 2 | | 2'-5'-Oligoadenylate-Binding Protein2 3 | | RNASELI1 2 3 5 | | RNase L Inhibitor2 3 | | RNS4I1 2 3 5 | | ABC382 | | RLI1 2 3 | | ATP-Binding Cassette Sub-Family E Member 12 | | RNASEL11 2 3 | | HuHP683 | | OABP1 2 | | Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) Inhibitor2 | | Ribonuclease 4 Inhibitor2 3 | | HuHP683 |
Export aliases for ABCE1 gene to outside databasesPrevious GC identifers: GC04P146819 GC04P146391 GC04P146597 GC04P146377 GC04P146238 GC04P141750 |
Summaries for ABCE1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ABCE1: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily.Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L.Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathwayfor viral interferon action. Two transcript variants encoding the same protein have been found for this gene.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: ABCE1_HUMAN, P61221Function: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through directinteraction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in theregulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. Mayact as a chaperone for post-translational events during HIV-1 capsid assembly
|
Genomic Views for ABCE1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ABCE1 gene promoter: E2F-1 E2F Pbx1a AML1a Cart-1 E2F-2 LCR-F1 MRF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCE1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCE1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q31 Ensembl cytogenetic band: 4q31.21 HGNC cytogenetic band: 4q31ABCE1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P146019: view genomic region
(about GC identifiers)
Start:
|
146,019,084 bp from pter |
End:
|
146,050,676 bp from pter |
Size:
|
31,593 bases |
Orientation:
|
plus strand |
|
Proteins for ABCE1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ABCE1_HUMAN, P61221 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family E member 1 Size: 599 amino acids; 67314 Da
Subunit: Probably heterodimerizes with RNASEL; this interaction inhibits the RNASEL. Associates with HIV-1 Vif andHIV-1, HIV-2 and SIV Gag proteins
Subcellular location: Cytoplasm. Mitochondrion. Note=Localized to clusters of virus formation at the plasma membrane
Miscellaneous: The ABC transporter domains seem not to be functional
Secondary accessions: O88793 Q13181 Q13864 Q6NR76 Q96AL0 Q96B10 Q99K66Explore the universe of human proteins at neXtProt for ABCE1: NX_P61221
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P61221 ABCE1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001035809.1 NP_002931.2 ENSEMBL proteins: ENSP00000296577 ENSP00000421250 ENSP00000422068 ENSP00000423415 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ABCE1 for ontologies About GeneDecksing
ABCE1 Antibody Products: Assay Products for ABCE1: |
Protein
Domains / Families for ABCE1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCE1 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry P61221ProtoNet protein and cluster: P61221 2 Blocks protein families: IPB007209 Possible metal-binding region in RNase L inhibitor IPB013283 ABC transporter family E signature
UniProtKB/Swiss-Prot: ABCE1_HUMAN, P61221Similarity: Belongs to the ABC transporter superfamily. ABCE familySimilarity: Contains 2 4Fe-4S ferredoxin-type domainsSimilarity: Contains 2 ABC transporter domains |
Function for ABCE1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ABCE1_HUMAN, P61221Function: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through directinteraction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in theregulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. Mayact as a chaperone for post-translational events during HIV-1 capsid assemblyInduction: Activated by encephalomyocarditis virus (EMCV) and HIV-1 Genatlas biochemistry entry for ABCE1:ATP binding cassette superfamily,subfamilyE (OABP),member 1,ubiquitously expressed
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCE1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCE1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ABCE1 (NM_001040876) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCE1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCE1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCE1 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
ABCE1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for ABCE1: Animal Models: 1 MGI phenotypic allele for Abce1 (no phenotypes)
ABCE1 for phenotypes About GeneDecksing
|
Pathways & Interactions for ABCE1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABCE1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/110 Interacting proteins for ABCE1 (P612213 ENSP000002965774) via UniProtKB, MINT, STRING, and/or I2D (see all 110)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
ABCE1 for ontologies About GeneDecksing
|
Drugs & Compounds for ABCE1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ABCE1
1 DrugBank Compound for ABCE1 About this table
Search CenterWatch for drugs/clinical trials and news about ABCE1 
|
Transcripts for ABCE1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ABCE1 gene (2 alternative transcripts): NM_001040876.1 NM_002940.2 Unigene Cluster for ABCE1: ATP-binding cassette, sub-family E (OABP), member 1 Hs.12013 [show with all ESTs]Unigene Representative Sequence: NM_00294010 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000296577(uc003ijx.3 uc003ijy.3 uc010iot.3) ENST00000502586 ENST00000502803 ENST00000507193 ENST00000506506 ENST00000504292 ENST00000515678 ENST00000509593 ENST00000510321 ENST00000504683
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCE1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCE1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ABCE1 (NM_001040876) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCE1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCE1  |
Additional cDNA sequence: AB062293.1 AK123593.1 AK315198.1 BC016283.1 BC016988.1 BT009779.1 X74987.1 X76388.1 13 DOTS entries: DT.448327 DT.92453076 DT.101977083 DT.95306496 DT.121341907 DT.100800662 DT.100800665 DT.99981971 DT.121275165 DT.121427773 DT.95306494 DT.121275160 DT.99928359 24/351 AceView cDNA sequences (see all 351): BI495011 CA430799 AI253209 BU616894 AI205870 BU686342 BM970266 AI970155 T34234 BG741599 BX116792 AI919038 AW009691 BM457986 BU189552 BM981410 BM833583 BM975279 BC016283 BG571761 BM504188 AI564670 BM974936 BX489818 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ABCE1 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | - |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ABCE1
|
Expression for ABCE1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCE1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See ABCE1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ABCE1
SOURCE GeneReport for Unigene cluster: Hs.12013 SABiosciences Custom PCR Arrays for ABCE1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCE1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCE1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCE1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCE1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCE1 |
Orthologs for ABCE1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ABCE1 gene from 11/44 species (see all 44) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Abce11 , 5 |
ATP-binding cassette, sub-family E (OABP), member 11, 5 |
93.04(n)1 100(a)1 |
  |
8 (37.77 cM)5 240151 NM_015751.21 NP_056566.21 796834425 |
chicken (Gallus gallus) |
Aves |
ABCE11 |
ATP-binding cassette, sub-family E (OABP), member 1 |
85.87(n) 98.83(a) |
  |
422462 NM_001006440.1 NP_001006440.1 |
lizard (Anolis carolinensis) |
Reptilia |
ABCE16 |
-- |
97(a) |
1 ↔ 1 |
5(117947336-117960725) |
African clawed frog (Xenopus laevis) |
Amphibia |
BC046573.12 |
-- |
80.04(n) |
  |
BC046573.1 |
zebrafish (Danio rerio) |
Actinopterygii |
AY391404.12 |
-- |
77.91(n) |
  |
AY391404.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG56513 pix1 |
ribonuclease inhibitor3 pixie1 |
76(a)3 66.11(n)1 77.39(a)1 |
  |
66E53 390271 NM_168306.11 NP_729435.11 |
worm (Caenorhabditis elegans) |
Secernentea |
Y39E4B.13 abce-11 |
Protein ABCE-11 |
65(a)3 61.93(n)1 67.34(a)1 |
  |
III(13225073-13227795)3 1767331 NM_067316.31 NP_499717.11 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
RLI1(YDR091C)4 RLI11 |
Essential iron-sulfur protein required for ribosome more4 Rli1p1 |
64.44(n)1 69.12(a)1 |
  |
4(628534-626708)4 8516651, 4 NP_010376.31 NP_010376.14 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
RLI21 |
ABC transporter E family member 2 |
67.45(n) 75.79(a) |
  |
827661 NM_118041.4 NP_193656.2 |
rice (Oryza sativa) |
Liliopsida |
AK102362.12 |
-- |
76.33(n) |
  |
AK102362.1 |
ENSEMBL Gene Tree for ABCE1 (if available) TreeFam Gene Tree for ABCE1 (if available)  |
Paralogs for ABCE1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ABCE1 gene
ABCE1 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for ABCE1 PGOHUM00000244380 PGOHUM00000251144 PGOHUM00000232615
|
Genomic Variants for ABCE1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCE1 |
|
Disorders
/ Diseases for ABCE1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCE1 for disorders About GeneDecksing
OMIM gene information: 601213
OMIM disorders: --
9 diseases for ABCE1: About MalaCardsmedian neuropathy ulnar neuropathy neuropathy colon cancer lung cancer prostate cancer prostatitis immunodeficiency malaria Human Genome Epidemiology (HuGE) Navigator: ABCE1 (2 documents) Export disorders for ABCE1 gene to outside databases
|
Publications for ABCE1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCE1 gene, integrated from 9 sources (see all 49): (articles sorted by number of sources associating them with ABCE1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and characterization of a RNase L inhibitor. A new component of the interferon-regulated 2-5A pathway. (PubMed id 7539425)1, 2, 3 Bisbal C.... Salehzada T. (1995)
- Conservation of a stepwise, energy-sensitive pathway involving HP68 for assembly of primate lentivirus capsids in cells. (PubMed id 14747530)1, 2 Dooher J.E. and Lingappa J.R. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of a host protein essential for assembly of immature HIV-1 capsids. (PubMed id 11780123)1, 2 Zimmerman C.... Lingappa J.R. (2002)
- The 2-5A/RNase L/RNase L inhibitor (RNI) pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells. (PubMed id 11585831)1, 2 Le Roy F....Salehzada T. (2001)
- RNase L inhibitor is induced during human immunodeficiency virus type 1 infection and down regulates the 2-5A/RNase L pathway in human T cells. (PubMed id 9847332)1, 2 Martinand C....Bisbal C. (1999)
- RNase L inhibitor (RLI) antisense constructions block partially the down regulation of the 2-5A/RNase L pathway in encephalomyocarditis- virus-(EMCV)-infected cells. (PubMed id 9660177)1, 2 Martinand C.... Bisbal C. (1998)
- Chromosomal localization and expression pattern of the RNase L inhibitor gene. (PubMed id 8641422)1, 2 Aubry F.... Galibert F. (1996)
- Basic residues in the nucleocapsid domain of Gag are required for interaction of HIV-1 gag with ABCE1 (HP68), a cellular protein important for HIV-1 capsid assembly. (PubMed id 16275648)1, 9 Lingappa J.R....Klein K.C. (2006)
- ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients. (PubMed id 15809757)1, 9 Shichijo S....Itoh K. (2005)
|
External Searches for ABCE1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ABCE1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCE1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABCE1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ABCE1 | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/abce1/ | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=P61221 |
|
| | |
About This Section
| Patent Information for ABCE1 gene: Search GeneIP for patents involving ABCE1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ABCE1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | OriGene Antibodies for ABCE1 | | OriGene shRNA RFP for ABCE1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCE1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCE1 | | OriGene Protein Over-expression Lysate for ABCE1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ABCE1 | | OriGene 3'-UTR Clone for ABCE1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCE1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCE1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for ABCE1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ABCE1 | | OriGene Custom Protein Services for ABCE1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCE1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCE1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCE1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCE1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCE1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCE1 |
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| | | Search Tocris compounds for ABCE1 |
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 | | ABCE1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCE1 |
|  |  |  | | | ThermoFisher Antibodies for ABCE1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCE1 |
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