ABCD3 Gene
protein-coding GIFtS: 64
GCID: GC01P094883
|
|
ATP-binding cassette, sub-family D (ALD), member 3
(Previous symbol: PXMP1)
| |
Aliases
for ABCD3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family D (ALD), Member 31 2 | | ABC432 | | PMP701 2 3 5 | | ATP-Binding Cassette Sub-Family D Member 32 | | PXMP11 2 3 5 | | DJ824O18.1 (ATP-Binding Cassette, Sub-Family D (ALD), Member 3 (PMP70, PXMP1))2 | | ZWS21 2 | | Peroxisomal Membrane Protein 1 (70kD, Zellweger Syndrome)2 | | 70 KDa Peroxisomal Membrane Protein2 3 | | Peroxisomal Membrane Protein-1 (70kD)2 |
Export aliases for ABCD3 gene to outside databasesPrevious GC identifers: GC01P095285 GC01P094089 GC01P094234 GC01P094355 GC01P094596 GC01P094656 GC01P093005 |
Summaries
for ABCD3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABCD3:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily,which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomalABC transporters are half transporters which require a partner half transporter molecule to form a functionalhomodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role inperoxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group ofperoxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinctisoforms. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ABCD3_HUMAN, P28288Function: Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity
Gene Wiki entry for ABCD3
|
Genomic Views
for ABCD3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABCD3 gene promoter:
AML1a FOXF2 POU6F1 (c2) Nkx2-5 C/EBPalpha GATA-1 Egr-2 S8 SRY Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCD3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCD3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p21.3 Ensembl cytogenetic band: 1p21.3 HGNC cytogenetic band: 1p21.3ABCD3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P094883: view genomic region
(about GC identifiers)
Start:
|
94,883,933 bp from pter |
End:
|
94,984,222 bp from pter |
Size:
|
100,290 bases |
Orientation:
|
plus strand |
|
Proteins
for ABCD3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ABCD3_HUMAN, P28288 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family D member 3 Size: 659 amino acids; 75476 Da
Subunit: Can form heterodimers with ABCD1/ALD and ABCD2/ALDR. Dimerization is necessary to form an active transporter.Interacts with PEX19
Subcellular location: Peroxisome membrane; Multi-pass membrane protein
Miscellaneous: Mutation in ABCD3 have been found in two individuals affected by Zellweger syndrome. However, the roleof ABCD3 in the causation of Zellweger syndrome remains uncertain
Secondary accessions: D3DT46 Q15271 Q6NUN5 Q96DA3 Q9H529Alternative splicing: 3 isoforms: P28288-1 P28288-2 P28288-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ABCD3: NX_P28288
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P28288
ABCD3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001116146.1 NP_002849.1
ENSEMBL proteins: ENSP00000359233 ENSP00000326880 ENSP00000377780 ENSP00000403357 ENSP00000440692 Reactome Protein details: P28288
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
ABCD3 for ontologies About GeneDecksing
ABCD3 Antibody Products:
Assay Products for ABCD3: |
Protein
Domains /
Families
for ABCD3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCD3 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry P28288ProtoNet protein and cluster: P28288 1 Blocks protein family: IPB010509 ABC transporter
UniProtKB/Swiss-Prot: ABCD3_HUMAN, P28288Similarity: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC3.A.1.203) subfamilySimilarity: Contains 1 ABC transmembrane type-1 domainSimilarity: Contains 1 ABC transporter domain |
Function
for ABCD3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ABCD3_HUMAN, P28288Function: Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity Genatlas biochemistry entry for ABCD3:ATP binding cassette superfamily,subfamily D (ALD),member 3,peroxisomal membrane protein,involved in the peroxisomalimport of fatty acid or fatty acyl coA,see ZWS2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCD3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCD3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ABCD3 (NM_002858) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCD3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCD3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCD3 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
ABCD3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ABCD3:
|
Pathways & Interactions
for ABCD3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | Nuclear receptors in lipid metabolism and toxicity | | | 3 | Peroxisome | | | 4 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for ABCD3
3 
Reactome Pathways for ABCD3
2 
Kegg Pathways (Kegg details for ABCD3):
ABCD3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABCD3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/33 Interacting proteins for ABCD3 (P282881, 2, 3 ENSP000003592334) via UniProtKB, MINT, STRING, and/or I2D (see all 33)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ABCD1 | P338971, 3, ENSP000002181044 | EBI-80992,EBI-81045 I2D:
score=5 STRING: ENSP00000218104 | | PEX19 | P408551, 2, 3, ENSP000003570514 | EBI-80992,EBI-981972 MINT-8089481 MINT-8089465 I2D:
score=6 STRING: ENSP00000357051 | | BRF2 | Q9HAW03, ENSP000002206594 | I2D:
score=2 STRING: ENSP00000220659 | | MLF2 | Q157733, ENSP000002036304 | I2D:
score=2 STRING: ENSP00000203630 | | PELO | Q9BRX23, ENSP000002743114 | I2D:
score=2 STRING: ENSP00000274311 |
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
ABCD3 for ontologies About GeneDecksing
|
Drugs & Compounds
for ABCD3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ABCD3 for compounds About GeneDecksing
 Browse Tocris compounds for ABCD3
4 Novoseek chemical compound relationships for ABCD3 gene About this table
Search CenterWatch for drugs/clinical trials and news about ABCD3
|
Transcripts
for ABCD3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABCD3 gene (2 alternative transcripts): NM_001122674.1 NM_002858.3 Unigene Cluster for ABCD3: ATP-binding cassette, sub-family D (ALD), member 3 Hs.700576 [show with all ESTs]Unigene Representative Sequence: BX6487159 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000370214(uc001dqn.4 uc010oto.2 uc010otp.2) ENST00000315713(uc001dqm.4)
ENST00000468860 ENST00000493416 ENST00000484213(uc001dqo.4) ENST00000464165
ENST00000394233(uc009wdr.3) ENST00000454898 ENST00000536817
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCD3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCD3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ABCD3 (NM_002858) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCD3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCD3 |
Additional cDNA sequence: AK126440.1 AK296791.1 AK302714.1 AK308159.1 BC009712.2 BC068509.1 BT006644.1 BX648715.1 M81182.1 X58528.1 16 DOTS entries: DT.117127 DT.100036367 DT.101958761 DT.100798387 DT.97858768 DT.97815054 DT.95165005 DT.92442676 DT.95081624 DT.121420094 DT.95165015 DT.95165017 DT.95261027 DT.97786392 DT.75133855 DT.91979646 24/228 AceView cDNA sequences (see all 228): AA013086 BF002935 AL603048 AA020969 BF968869 AU128317 H25922 BM055442 AA576086 BM974900 N85752 BU736454 N29142 CA431008 AA013052 AU128259 BU683773 CB161901 BM928546 AA013345 R95434 CB132791 CB160218 N53598
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ABCD3 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ABCD3
|
Expression
for ABCD3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTGAATTAT
About this image
See ABCD3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABCD3
SOURCE GeneReport for Unigene cluster: Hs.700576
SABiosciences Expression via Pathway-Focused PCR Array including ABCD3:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCD3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCD3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCD3 |
Orthologs
for ABCD3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ABCD3 gene from 9/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ABCD31 |
ATP-binding cassette, sub-family D (ALD), member 3 |
81.89(n)
88.89(a) |
|
424487 NM_001012597.1 NP_001012615.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ABCD36 |
-- |
85(a) |
1 ↔ 1 |
4(89053018-89085566) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.14982 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.22(n) |
|
BX845528.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.36142 |
Danio rerio mRNA similar to ATP-binding cassette, sub-family more |
77.97(n) |
|
BC044468.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG127031 , 3 |
peroxisome organization and biogenesis
ATP-binding more3
CG127031 |
59(a)3
56.48(n)1
60.03(a)1 |
|
18F13
329921 NM_134510.11 NP_608354.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C44B7.93
pmp-21 |
peroxisomal membrane protein (PMP70, an
ATP-binding more3
Protein PMP-21 |
61(a)
(best of 2)3
61.64(n)1
61.8(a)1 |
|
II(6884046-6887635)3
1741271 NM_063007.31 NP_495408.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
PXA11 |
ABC transporter D family member 1 |
46.86(n)
37.48(a) |
|
830144 NM_001204044.1 NP_001190973.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.289882 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
74.62(n) |
|
NM_189403.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
yddA6 |
fused predicted multidrug transporter subunits of ... |
19(a) |
1 → many |
Chromosome(1575681-1577366) |
ENSEMBL Gene Tree for ABCD3 (if available)
TreeFam Gene Tree for ABCD3 (if available) |
Paralogs
for ABCD3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABCD3 gene
- ABCD12 ABCD42 ABCD22
4 SIMAP similar genes for ABCD3 using alignment to 3 protein entries: ABCD3_HUMAN (see all proteins):ABCD1 ALD ABCD2 ABCD4
ABCD3 for paralogs About GeneDecksing
|
Genomic Variants
for ABCD3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCD3 (94883933 - 94984222 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ABCD3
1 Indel: 41329
Human Gene Mutation Database (HGMD): ABCD3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCD3 |
|
Disorders
/ Diseases
for ABCD3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCD3 for disorders About GeneDecksing
OMIM gene information: 170995
OMIM disorders: --
13  diseases for ABCD3: About MalaCardszellweger syndrome peroxisomal biogenesis disorder peroxisome biogenesis disorders zellweger syndrome-2
adrenoleukodystrophy peroxisomal disease protein s deficiency colon carcinoma
cholesterol tuberculosis carcinoma neuronitis
mycobacterium tuberculosis
2 diseases from the University of Copenhagen DISEASES database for ABCD3:Adrenoleukodystrophy Peroxisomal disease 2 Novoseek disease relationships for ABCD3 gene About this table
Human Genome Epidemiology (HuGE) Navigator: ABCD3 (8 documents)
Export disorders for ABCD3 gene to outside databases
|
Publications
for ABCD3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCD3 gene, integrated from 9 sources (see all 85):
(articles sorted by number of sources associating them with ABCD3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. (PubMed id 1301993)1, 2, 3, 9 Gaertner J.... Valle D. (1992)
- Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1). (PubMed id 9521874)1, 2, 9 Gaertner J.... Valle D. (1998)
- Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters. (PubMed id 11248239)1, 2, 9 Roerig P.... Gaertner J. (2001)
- Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p. (PubMed id 10777694)1, 2, 9 Gloeckner C.J.... Roscher A.A. (2000)
- Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters. (PubMed id 1536884)1, 2, 9 Kamijo K.... Hashimoto T. (1992)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. (PubMed id 10704444)1, 2 Sacksteder K.A.... Gould S.J. (2000)
- Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters. (PubMed id 10551832)1, 2 Liu L.X....Aubourg P. (1999)
- Localization of the 70-kDa peroxisomal membrane protein to human 1p21-p22 and mouse 3. (PubMed id 8449508)1, 3 Gartner J....Valle D. (1993)
- Role of Pex19p in the targeting of PMP70 to peroxisome. (PubMed id 16344115)1, 9 Kashiwayama Y....Imanaka T. (2005)
|
External Searches for ABCD3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ABCD3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCD3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABCD3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for ABCD3 | Pharmacogenomics, SNPs, Pathways | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=P28288 |
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About This Section
| Patent Information for ABCD3 gene:
Search GeneIP for patents involving ABCD3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ABCD3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for ABCD3 | | OriGene shRNA RFP for ABCD3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCD3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCD3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABCD3 | | OriGene 3'-UTR Clone for ABCD3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCD3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCD3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABCD3 | | OriGene Custom Protein Services for ABCD3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCD3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCD3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCD3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCD3 |
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| | | | Search Tocris compounds for ABCD3 |
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 | | | ABCD3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCD3 |
|  |  |  | | | | ThermoFisher Antibody for ABCD3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCD3 |
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