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ABCC9 Gene

protein-coding   GIFtS: 63

GC12M021844
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
ABC37 2
CMD1O 1, 2, 5
FLJ36852 2
SUR2 1, 2, 3, 5
Descriptions
ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2
ATP-binding cassette, sub-family C, member 9 2
Sulfonylurea receptor 2 3
sulfonylurea receptor 2A 2
External Ids
HGNC: 601
Entrez Gene: 100602
UniProtKB: O607063
Ensembl: ENSG000000694317
Search outside databases for aliases for ABCC9 gene

Previous GC identifers: GC12M022239 GC12M021955 GC12M021852 GC12M021845

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ABCC9:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)
transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20,
White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance.
This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and
vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding
channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has
been associated with this gene thus far. Alternative splicing of this gene results in several
products, two of which result from differential usage of two terminal exons and one of which
results from exon deletion. [provided by RefSeq]

UniProtKB/Swiss-Prot: ABCC9_HUMAN, O60706
Function: Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth
muscle-type KATP channels with KIR6.2. KIR6.2 forms the channel pore while SUR2 is required for
activation and regulation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ABCC9 gene  

Entrez Gene cytogenetic band: 12p12.1   Ensembl cytogenetic band:  12p12.1   HGNC cytogenetic band: 12p12.1

ABCC9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M021844:     (about GC identifiers)

Start:
21,841,590 bp from pter
End:
21,985,603 bp from pter
Size:
144,014 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000012.10  NT_009714.16  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ABCC9_HUMAN, O60706 (See protein sequence)
Recommended Name: ATP-binding cassette transporter sub-family C member 9  
Size: 1549 amino acids; 174223 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: O60707
Alternative splicing: 2 isoforms:  O60706-1   O60706-2   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins (3 alternative transcripts): 
    NP_005682.2  NP_064693.2  NP_064694.2  


    ENSEMBL proteins: 
    ENSP00000261201 ENSP00000317518 ENSP00000261200 ENSP00000261202 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ABCC9)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008282 ATP-sensitive potassium channel complex ISS--
    GO:0016020 membrane IEA--
    GO:0016021 integral to membrane IEA--
    About this table

    Antibodies for ABCC9: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ABCC9
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (ABCC9), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for ABCC9

    Assays for ABCC9: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    5/7 InterPro domains/families (see all 7 ):
     IPR003593 ATPase_AAA+_core
     IPR001475 Sulphonylurea_rcpt_2_N
     IPR003439 ABC_transporter-like
     IPR000388 Sulphorea_rcpt_N
     IPR017940 ABC_transporter_type1


       GeneDecks  ABCC9 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry O60706

    ProtoNet protein and cluster: O60706

    2 Blocks protein families:
    IPB000388 Sulphonylurea receptor family signature
    IPB001475 Sulphonylurea receptor type 2 family signature


    UniProtKB/Swiss-Prot: ABCC9_HUMAN, O60706
    Similarity: Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily
    Similarity: Contains 2 ABC transmembrane type-1 domains
    Similarity: Contains 2 ABC transporter domains

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ABCC9)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ABCC9)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_020297

                  Applied Biosystems Silencer® siRNAs for ABCC9

                  Sigma-Aldrich siRNA and siRNA Panels for ABCC9  
                         Sigma-Aldrich shRNA for ABCC9  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ABCC9
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_005691
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_005691
                                     untagged cDNA clones in CMV expression vector (see all 4): BC033804 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_020297

    UniProtKB/Swiss-Prot: ABCC9_HUMAN, O60706
    Function: Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth
    muscle-type KATP channels with KIR6.2. KIR6.2 forms the channel pore while SUR2 is required for
    activation and regulation

    Genatlas biochemistry entry for ABCC9:
    ATP-binding cassette superfamily,subfamily C (CFTR/MRP),member 9

    5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Abcc9):

    growth/sizehomeostasis/metabolismlife span-post-weaning/agingmuscle

    5/8 Gene Ontology (GO) molecular function terms (links to tree view) (see all 8 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0004872 receptor activity IEA--
    GO:0005215 transporter activity TAS8826984
    GO:0005524 ATP binding IEA--
    GO:0008281 sulfonylurea receptor activity TAS8826984
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for ABCC9
      outward current

       GeneDecks  ABCC9 for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for ABCC9):
     hsa02010 ABC transporters

       GeneDecks  ABCC9 for the pathways selected above  
    About GeneDecksing

    2 Interacting proteins for ABCC9 (ENSP000002612013) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KCNJ11ENSP000003457083STRING (score=.936)
    KCNJ8ENSP000002406623STRING (score=.855)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810 transport IEA--
    GO:0010107 potassium ion import ISS--
    GO:0051607 defense response to virus IMP18026101
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ABCC9
    6 Novoseek chemical compound relationships for ABCC9 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    sulfonylurea 92.64 18 16672225 (2), 17110465 (1), 10469651 (1), 8630239 (1) (see all 16)
    katp 91.91 36 8826984 (2), 10224138 (2), 11054556 (2), 10099692 (1) (see all 27)
    mgatp 71.55 4 10436001 (1), 12145099 (1), 15023854 (1), 11714894 (1)
    mgadp 71.27 3 12145099 (1), 11714894 (1), 12475777 (1)
    potassium 65.77 4 10469651 (1), 10436001 (1), 18316485 (1), 12959913 (1)
    atp 45.02 15 10436001 (4), 10224138 (2), 9692785 (1), 9755153 (1) (see all 7)
    About this table

    2 PharmGKB drug compound relationships for ABCC9 gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    antiarrhythmicsFA  8630239
    diazoxideFA  8630239
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ABCC9)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ABCC9)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_020297

                  Sigma-Aldrich siRNA and siRNA Panels for ABCC9  
                         Sigma-Aldrich shRNA for ABCC9  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_005691  NM_020297  NM_020298  

    REFSEQ mRNAs for ABCC9 gene (3 alternative transcripts): 

    NM_005691.2   NM_020297.2   NM_020298.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_005691  NM_020297  NM_020298  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_005691
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_005691
                                     untagged cDNA clones in CMV expression vector (see all 4): BC033804 

    Additional cDNA sequence: 

    AK056519.1 AK092535.1 AK094171.1 BC033804.1 BX537513.1 BX640893.1 CR619334.1 

    5 DOTS entries:

    DT.40189058  DT.315094  DT.95267937  DT.99932355  DT.99954570 

    24/56 AceView cDNA sequences (see all 56 ):

    CR619334 BE148672 AK092535 CA389699 CA390366 AA687622 AA233923 AA716277 
    AA329631 AW172466 BX640893 AK056519 BG564434 AA234172 BQ004763 BX432024 
    CA389496 BX104670 NM_020297 AI015113 CD630005 BX499619 AA452215 NM_020298 

    highest scoring ESTs for ABCC9:

    BI763735 BX497417 H16193 R73927 AA234172 AA452215 AK056519 AW172466 BC033804 BE550227 

    Unigene Cluster for ABCC9:

    ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    Hs.446050  [show with all ESTs]
    Unigene Representative Sequence: NM_020297


    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ABCC9

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21
    SP1:                                                                                                                                          
    SP2:                                            -                                                                                             
    SP3:                    -                                                                                                                     

    About this scheme

    ECgene alternative splicing isoforms for ABCC9

    4 Ensembl transcripts including schematic representations:
    ENST00000261201  ENST00000326684  ENST00000261200  ENST00000345162  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ABCC9 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ABCC9

    1 / 2 / 3

    13 probe-sets matching ABCC9 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    75176_at2, 3 U95-E 1 1.00 1.00 0.96 2.01 AA234172 0.60 1.00 0.82 1
    37260_at2, 3 U95-A 1 1.00 1.00 0.92 0.62 AF061324 0.20 1.00 0.72 1
    37262_at2, 3 U95-A 1 0.94 1.00 0.26 1.13 AF061324 0.20 1.00 0.72 1

    37261_g_at2, 3 U95-A 2 0.94 0.97 0.96 0.48 AF061324 0.20 1.00 0.72 1

    208561_at2, 3 U133-A 1 1.00 1.00 -- -- NM_020297 0.60 1.00 0.82 1

    208562_s_at2, 3 U133-A 2 1.00 0.95 -- -- NM_020297 0.60 1.00 0.82 1

    208462_s_at2, 3 U133-A 1 0.91 1.00 -- -- NM_005691 0.60 1.00 0.82 1

    206323_x_at2 U133-A 32 0.82 0.10 -- -- -- -- -- -- --

    1557374_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    208561_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    208562_s_at2 U133Plus2 2 1.00 0.95 -- -- -- -- -- -- --

    208462_s_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --

    206323_x_at2 U133Plus2 32 0.82 0.10 -- -- -- -- -- -- --
    GeneDecks  ABCC9 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.446050

    Expression variation in blood from EXPOLDB for ABCC9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ABCC9 gene from 5/12 species (see all 12 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ABCC91   -- ATP-binding cassette, sub-family C (CFTR/MRP), member more 92.81(n)
    98.77(a)
    486638  XM_847653.1  XP_852746.1 
    chimpanzee
    (Pan troglodytes)
    ABCC91   -- ATP-binding cassette, sub-family C (CFTR/MRP), member more 99.74(n)
    99.94(a)
    465338  XM_001149571.1  XP_001149571.1 
    cow
    (Bos taurus)
    ABCC91   -- ATP-binding cassette, sub-family C (CFTR/MRP), member more 91.85(n)
    98.53(a)
    522913  XM_601202.3  XP_601202.3 
    rat
    (Rattus norvegicus)
    Abcc91   -- ATP-binding cassette, sub-family C (CFTR/MRP), member more 85.13(n)
    97.22(a)
    25560  NM_013040.2  NP_037172.2 
    mouse
    (Mus musculus)
    Abcc91, 5 6 (70.00 cM)5
    ATP-binding cassette, sub-family C (CFTR/MRP), member more1, 5 85.96(n)1
    97.09(a)1
    209281  NM_011511.21  NP_035641.11 
     AF0035315  AI4140275  (see all 14)
    About this table        Species with no ortholog for ABCC9

    ENSEMBL Gene Tree for ABCC9
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ABCC9 gene
    ABCC102  CFTR2  ABCC82  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/787 NCBI SNPs in ABCC9 are shown (see all 787 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 287)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 12 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs73162711,2
    A,C,F,H21981729(+) agtgaT/Cgtgct 3 -- ng318Minor allele frequency- C:0.37EU EA WA 838
    rs118350911,2
    A,C,F,H21841965(+) GTGCAT/CAATTG 1 -- ut314Minor allele frequency- C:0.01EU EA WA 418
    rs116153101,2
    A,C,F,H21982585(+) AAGGTA/GTTAAT 3 -- ng314Minor allele frequency- G:0.02EU EA WA 418
    rs118326761,2
    C,F,H21841862(+) GTCCCG/AAATCT 1 -- ut314Minor allele frequency- A:0.01EU EA WA 418
    rs107347151,2
    C,H21981765(+) tattaT/Atgctg 3 -- ng314Minor allele frequency- A:0.00EU EA WA 420
    rs38092061,2
    F,H21981342(-) ACTCTG/ATCACA 3 -- ng315Minor allele frequency- A:0.02EA EU WA 1724
    rs12837841,2
    F,H21844726(+) AGGCTC/GTTAAG 1 -- ut314Minor allele frequency- G:0.03EU EA WA 416
    rs8290631,2
    F,H21844204(+) TGATCA/TTGTGT 1 -- ut314Minor allele frequency- T:0.03EU EA WA 418
    rs41486811,2
    H21849178(-) TGTGTT/GTTCAA 3 -- ng51 int14Minor allele frequency- G:0.00EU EA WA 416
    --
    rs176309221,2
    F21849105(+) GAAATT/GGGTCC 3 -- ng51 int13Minor allele frequency- G:0.01NA 142
    About this table

    HapMap Linkage Disequilibrium images for ABCC9 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 601439   disorders: 608569  

    UniProtKB/Swiss-Prot: ABCC9_HUMAN, O60706

  • Defects in ABCC9 are the cause of cardiomyopathy dilated type 1O (CMD1O) [MIM:608569];
    also known as dilated cardiomyopathy with ventricular tachycardia. Dilated cardiomyopathy is a
    disorder characterized by ventricular dilation and impaired systolic function, resulting in
    congestive heart failure and arrhythmia. Patients are at risk of premature death
  • 1 Novoseek disease relationship for ABCC9 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 0.00 1 16829188 (1)
    About this table

    GeneTests: ABCC9
    Dilated Cardiomyopathy

    Human Gene Mutation Database: ABCC9
    Human Genome Epidemiology Navigator: ABCC9 (2 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/81 PubMed articles for ABCC9 gene (see all 81 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 10060 HGNC: 60 AceView: ABCC9 Ensembl:ENSG00000069431 euGenes: HUgn10060
    ECgene: ABCC9 H-InvDB: ABCC9
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    GeneReviewshttp://www.genetests.org/query?gene=ABCC9
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ABCC9:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ABCC9-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ABCC9 Antibodies for ABCC9
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ABCC9 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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