Aliases for ABCC2 Gene
Aliases for ABCC2 Gene
External Ids for ABCC2 Gene
- HGNC: 53
- Entrez Gene: 1244
- Ensembl: ENSG00000023839
- OMIM: 601107
- UniProtKB: Q92887
Previous HGNC Symbols for ABCC2 Gene
- CMOAT
Previous GeneCards Identifiers for ABCC2 Gene
- GC10P100435
- GC10P100776
- GC10P101673
- GC10P101207
- GC10P101532
- GC10P095169
Summaries for ABCC2 Gene
-
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABCC2 Gene
ABCC2 (ATP Binding Cassette Subfamily C Member 2) is a Protein Coding gene. Diseases associated with ABCC2 include Dubin-Johnson Syndrome and Bilirubin Metabolic Disorder. Among its related pathways are Vinka Alkaloid Pathway, Pharmacokinetics and Constitutive Androstane Receptor Pathway. Gene Ontology (GO) annotations related to this gene include transporter activity and protein domain specific binding. An important paralog of this gene is ABCC3.
UniProtKB/Swiss-Prot for ABCC2 Gene
-
Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Additional gene information for ABCC2 Gene
- Monarch Initiative
- Search for ABCC2 at DataMed
- Search for ABCC2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABCC2 Gene
Genomics for ABCC2 Gene
GeneHancer (GH) Regulatory Elements for ABCC2 Gene
Regulatory Element Products
Genomic Locations for ABCC2 Gene
- chr10:99,782,598-99,852,576
- (GRCh38/hg38)
- Size:
- 69,979 bases
- Orientation:
- Plus strand
- chr10:101,542,463-101,611,949
- (GRCh37/hg19)
Genomic View for ABCC2 Gene
- Cytogenetic band:
-
- 10q24.2 by Ensembl
- 10q24.2 by Entrez Gene
- 10q24.2 by HGNC


RefSeq DNA sequence for ABCC2 Gene
Proteins for ABCC2 Gene
-
Protein details for ABCC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92887-MRP2_HUMAN
- Recommended name:
- Canalicular multispecific organic anion transporter 1
- Protein Accession:
- Q92887
- B2RMT8
- Q14022
- Q5T2B1
- Q92500
- Q92798
- Q99663
- Q9UMS2
Protein attributes for ABCC2 Gene
- Size:
- 1545 amino acids
- Molecular mass:
- 174207 Da
- Quaternary structure:
- No Data Available
Protein Expression for ABCC2 Gene
Post-translational modifications for ABCC2 Gene
- Glycosylation at posLast=77, posLast=1212, and Asn1011
Other Protein References for ABCC2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Recommended
No data available for DME Specific Peptides for ABCC2 Gene
Domains & Families for ABCC2 Gene
Gene Families for ABCC2 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- FDA approved drug targets
- Plasma proteins
- Predicted membrane proteins
- Transporters
Protein Domains for ABCC2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ABCC2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q92887UniProtKB/Swiss-Prot:
MRP2_HUMAN :- Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
- Family:
-
- Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Function for ABCC2 Gene
Molecular function for ABCC2 Gene
- GENATLAS Biochemistry:
- ATP binding cassette superfamily,subfamily C (CFTR/MRP),member 2,mainly expressed in canilicular membranes of hepatocytes,also present in other apical domains of prolonged cells,such as the epithelial cells of proximal tubule of kidney
- UniProtKB/Swiss-Prot Function:
- Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005215 | transporter activity | IEA | -- |
GO:0005515 | protein binding | IPI | 17825285 |
GO:0005524 | ATP binding | IEA | -- |
GO:0008514 | organic anion transmembrane transporter activity | IEA,TAS | 7559771 |
GO:0015127 | bilirubin transmembrane transporter activity | TAS | -- |
Phenotypes for ABCC2 Gene
- MGI mutant phenotypes for ABCC2:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for ABCC2:
Animal Models for ABCC2 Gene
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miRNA for ABCC2 Gene
- miRTarBase miRNAs that target ABCC2
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-
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available ABCC2 gene related products
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-
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for ABCC2 Gene
Localization for ABCC2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ABCC2 Gene
- Apical cell membrane; Multi-pass membrane protein.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0005887 | integral component of plasma membrane | IBA,IEA | -- |
GO:0009986 | cell surface | IDA | 17825285 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ABCC2 Gene
Pathways & Interactions for ABCC2 Gene
Pathways by source for ABCC2 Gene
1 Cell Signaling Technology pathway for ABCC2 Gene
7 BioSystems pathways for ABCC2 Gene
2 Reactome pathways for ABCC2 Gene
4 KEGG pathways for ABCC2 Gene
2 R&D Systems pathways for ABCC2 Gene
1 Qiagen pathway for ABCC2 Gene
Interacting Proteins for ABCC2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006810 | transport | TAS | 7559771 |
GO:0006855 | drug transmembrane transport | IEA | -- |
GO:0006979 | response to oxidative stress | IEA | -- |
GO:0007565 | female pregnancy | IEA | -- |
GO:0009408 | response to heat | IEA | -- |
No data available for SIGNOR curated interactions for ABCC2 Gene
Drugs & Compounds for ABCC2 Gene
(169) Drugs for ABCC2 Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, FDA Approved Drugs, HMDB, and Novoseek
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Docetaxel | Approved May 1996, Investigational | Pharma | Transporter, substrate | Microtubulin disassembly inhibitor, Tubulin and VEGF inhibitor, Taxanes | 2040 | |
Cisplatin | Approved | Pharma | Transporter, inducer | Inhibits DNA synthesis,chemotherapy drug, Potent pro-apoptotic anticancer agent; activates caspase-3, Platinum | 2906 | |
Methotrexate | Approved | Pharma | Transporter, substrate, inhibitor | Folate antagonist,inhibits DFHR | 1603 | |
Pravastatin | Approved | Pharma | Competitive, Inhibitor, Transporter, substrate, inhibitor | 154 | ||
Ritonavir | Approved, Investigational | Pharma | Transporter, substrate, inducer | HIV protease inhibitor | 897 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
3',4'-Dihydrodiol |
|
|
||||
O-Desmethylverapamil (D-702) |
|
|
(4) ApexBio Compounds for ABCC2 Gene
Compound | Action | Cas Number |
---|---|---|
CP 100356 hydrochloride | 142715-48-8 | |
Fumitremorgin C | 118974-02-0 | |
KS 176 | 1253452-78-6 | |
Vinblastine sulfate | Anti-mitotic agent | 143-67-9 |
Transcripts for ABCC2 Gene
mRNA/cDNA for ABCC2 Gene
- (5) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (76) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ABCC2 Gene
CRISPR Products
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Inhibitory RNA Products
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Clone Products
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- VectorBuilder custom plasmid, inducible vectors for ABCC2
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available ABCC2 gene related products
- orf clones - Search results for available ABCC2 gene related products
- Applied Biological Materials Clones for ABCC2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for ABCC2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Liver (Hepatobiliary System)
- Brain (Nervous System)
- Endothelium (Cardiovascular System)
- Epithelial Cells (Uncategorized)
mRNA differential expression in normal tissues according to GTEx for ABCC2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ABCC2 Gene
NURSA nuclear receptor signaling pathways regulating expression of ABCC2 Gene:
ABCC2SOURCE GeneReport for Unigene cluster for ABCC2 Gene:
Hs.368243mRNA Expression by UniProt/SwissProt for ABCC2 Gene:
Q92887-MRP2_HUMANEvidence on tissue expression from TISSUES for ABCC2 Gene
- Liver(4.8)
- Intestine(3.1)
- Kidney(3)
- Blood(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ABCC2 Gene
- ectoderm
- endoderm
- mesoderm
- digestive
- integumentary
- nervous
- urinary
- eye
- head
- mouth
- biliary tract
- gallbladder
- kidney
- liver
- pancreas
- stomach
- skin
Primer Products
-
OriGene qPCR primer pairs for ABCC2
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Orthologs for ABCC2 Gene
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
dog (Canis familiaris) |
Mammalia | ABCC2 33 |
|
||
MRP2 34 |
|
OneToOne | |||
cow (Bos Taurus) |
Mammalia | ABCC2 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Abcc2 33 |
|
||
mouse (Mus musculus) |
Mammalia | Abcc2 33 16 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | ABCC2 34 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | ABCC2 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | ABCC2 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | ABCC2 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | abcc2 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | abcc2 33 34 |
|
||
zgc66072 33 |
|
||||
fruit fly (Drosophila melanogaster) |
Insecta | Sur 35 |
|
|
|
MRP 34 |
|
ManyToMany | |||
CG6214 35 |
|
|
|||
worm (Caenorhabditis elegans) |
Secernentea | mrp-2 35 |
|
|
|
mrp-8 35 |
|
|
|||
mrp-3 34 |
|
ManyToMany | |||
mrp-7 35 |
|
|
|||
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | YCF1 34 |
|
OneToMany | |
NFT1 36 |
|
|
|||
thale cress (Arabidopsis thaliana) |
eudicotyledons | MRP1 33 |
|
||
wheat (Triticum aestivum) |
Liliopsida | Ta.9148 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
ManyToMany |
- Species where no ortholog for ABCC2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for ABCC2 Gene
(20) SIMAP similar genes for ABCC2 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for ABCC2 Gene
Variants for ABCC2 Gene
SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs112758556 | uncertain-significance, likely-benign, Dubin-Johnson syndrome, not specified | 99,830,429(+) | C/T | coding_sequence_variant, downstream_transcript_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant | |
rs113646094 | benign, likely-benign, not specified, Dubin-Johnson syndrome | 99,804,255(+) | C/G/T | coding_sequence_variant, non_coding_transcript_variant, synonymous_variant | |
rs1137968 | likely-benign, Dubin-Johnson syndrome | 99,847,104(+) | G/T | coding_sequence_variant, downstream_transcript_variant, genic_downstream_transcript_variant, non_coding_transcript_variant, synonymous_variant | |
rs138221862 | uncertain-significance, Dubin-Johnson syndrome | 99,832,112(+) | T/C | coding_sequence_variant, downstream_transcript_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant | |
rs138578110 | uncertain-significance, Dubin-Johnson syndrome | 99,851,890(+) | G/A/T | 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv506n106 | CNV | deletion | 24896259 |
esv3423829 | CNV | duplication | 20981092 |
nsv1046030 | CNV | loss | 25217958 |
nsv1137953 | CNV | deletion | 24896259 |
nsv825539 | CNV | loss | 20364138 |
nsv825540 | CNV | gain | 20364138 |
nsv831960 | CNV | gain | 17160897 |
Additional Variant Information for ABCC2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABCC2 Gene
Disorders for ABCC2 Gene

(14) MalaCards diseases for ABCC2 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
dubin-johnson syndrome |
|
|
bilirubin metabolic disorder |
|
|
intrahepatic cholestasis |
|
|
cholestasis |
|
|
hyperbilirubinemia, rotor type |
|
UniProtKB/Swiss-Prot
MRP2_HUMAN- Dubin-Johnson syndrome (DJS) [MIM:237500]: Autosomal recessive disorder characterized by conjugated hyperbilirubinemia, an increase in the urinary excretion of coproporphyrin isomer I, deposition of melanin-like pigment in hepatocytes, and prolonged retention of sulfobromophthalein, but otherwise normal liver function. {ECO:0000269 PubMed:10053008, ECO:0000269 PubMed:10464142, ECO:0000269 PubMed:11093739, ECO:0000269 PubMed:11266082, ECO:0000269 PubMed:11477083, ECO:0000269 PubMed:22290738, ECO:0000269 PubMed:25336012, ECO:0000269 PubMed:9425227}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for ABCC2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for ABCC2 Gene
Publications for ABCC2 Gene
- Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. (PMID: 11500505) Ito K … Cole SP (The Journal of biological chemistry 2001) 3 4 22 25 58
- A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. (PMID: 8797578) Taniguchi K … Kuwano M (Cancer research 1996) 2 3 4 22 58
- A nonsynonymous variation in MRP2/ABCC2 is associated with neurological adverse drug reactions of carbamazepine in patients with epilepsy. (PMID: 20216337) Kim WJ … Lee MG (Pharmacogenetics and genomics 2010) 3 22 44 58
- Genetic polymorphisms of MRP2 and UGT2B7 and gastrointestinal symptoms in renal transplant recipients taking mycophenolic acid. (PMID: 19730281) Yang JW … Min DI (Therapeutic drug monitoring 2009) 3 22 44 58
- UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients. (PMID: 19494809) van Schaik RH … van Gelder T (Clinical pharmacology and therapeutics 2009) 3 22 44 58
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- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 58 available ABCC2 Antibodies ranked by validation data
- Compare Top ABCC2 Antibodies
- antibodies-online: Search results for 5 available ABCC2 Elisa Kits ranked by validation data
- Compare Top ABCC2 Elisa Kits
- Recommended
- antibodies-online: Search results for 10 available ABCC2 Proteins ranked by validation data
- Compare Top ABCC2 Proteins
- GeneTex ABCC2 antibody for ABCC2
- Search GeneTex for Proteins for ABCC2
- ViGene Biosciences adenoviral particle packaged cDNA for ABCC2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ABCC2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ABCC2 gene
- Search ViGene Biosciences for ABCC2
- Santa Cruz Biotechnology (SCBT) Antibodies for ABCC2
- Search Santa Cruz Biotechnology (SCBT) for ABCC2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ABCC2
- Horizon Cell Lines for ABCC2
- genomics-online: cdna clones - Search results for available ABCC2 gene related products
- orf clones - Search results for available ABCC2 gene related products
- genomics-online: gRNA clones - Search results for available ABCC2 gene related products
- genomics-online: primer clones - Search results for available ABCC2 gene related products
- genomics-online: shRNA clones - Search results for available ABCC2 gene related products
Sources for ABCC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew