ABCC10 Gene
protein-coding GIFtS: 54
GCID: GC06P043442
|
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 1...
| |
Aliases
for ABCC10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 101 2 | | MRP71 2 3 5 | | SIMRP71 2 3 | | EST1827631 2 | | ATP-Binding Cassette Sub-Family C Member 102 3 | | Multidrug Resistance-Associated Protein 72 |
Export aliases for ABCC10 gene to outside databasesPrevious GC identifers: GC06U990186 GC06P043391 GC06P043503 GC06P043117 |
Summaries
for ABCC10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABCC10:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of theMRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoformshave been found for this gene.(provided by RefSeq, Nov 2010)
UniProtKB/Swiss-Prot: MRP7_HUMAN, Q5T3U5Function: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion
Gene Wiki entry for ABCC10
|
Genomic Views
for ABCC10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABCC10 gene promoter:
NF-1/L Spz1 Sp1 LCR-F1 C/EBPalpha E47 HEN1 AREB6 HFH-1 Hand1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCC10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCC10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p12.3ABCC10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P043442: view genomic region
(about GC identifiers)
Start:
|
43,395,104 bp from pter |
End:
|
43,418,168 bp from pter |
Size:
|
23,065 bases |
Orientation:
|
plus strand |
|
Proteins
for ABCC10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MRP7_HUMAN, Q5T3U5 (See
protein sequence)Recommended Name: Multidrug resistance-associated protein 7 Size: 1492 amino acids; 161629 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAA92227.1; Type=Erroneous initiation; Sequence=BAB15736.1; Type=Miscellaneous discrepancy;Note=Intron retention;
Secondary accessions: Q8NHX7 Q9H7N2 Q9NXY3 Q9UF48Alternative splicing: 2 isoforms: Q5T3U5-1 Q5T3U5-2 Explore the universe of human proteins at neXtProt for ABCC10: NX_Q5T3U5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5T3U5
ABCC10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001185863.1 NP_258261.2
ENSEMBL proteins: ENSP00000361593 ENSP00000361608 ENSP00000244533 ENSP00000409161 ENSP00000422699 Reactome Protein details: Q5T3U5
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
TAS | -- | | GO:0016021 | integral to membrane |
IEA | -- |
ABCC10 for ontologies About GeneDecksing
ABCC10 Antibody Products:
Assay Products for ABCC10: |
Protein
Domains /
Families
for ABCC10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCC10 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q5T3U5ProtoNet protein and cluster: Q5T3U5 UniProtKB/Swiss-Prot: MRP7_HUMAN, Q5T3U5Similarity: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamilySimilarity: Contains 2 ABC transmembrane type-1 domainsSimilarity: Contains 2 ABC transporter domains |
Function
for ABCC10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MRP7_HUMAN, Q5T3U5Function: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusionBiophysicochemical properties: Kinetic parameters: KM=57.8 uM for 17-beta-estradiol 17-(beta-D-glucuronide) (at 37degrees Celsius); Vmax=20 pmol/min/mg enzyme toward 17-beta-estradiol 17-(beta-D- glucuronide) (at 37 degreesCelsius); Genatlas biochemistry entry for ABCC10:ATP binding cassettte superfamily,subfamily C (CFTR/MRP),member 10
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCC10 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCC10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ABCC10 (NM_033450) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCC10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCC10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCC10 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005524 | ATP binding |
IEA | -- | | GO:0016887 | ATPase activity |
-- | -- | | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances |
IEA | -- |
ABCC10 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ABCC10:
Animal Models:
Mouse knock-out Abcc10tm1Eah for ABCC10
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Abcc10):
ABCC10 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ABCC10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | Tenofovir/Adefovir Pathway, Pharmacokinetics | | | 3 | SLC-mediated transmembrane transport | | | 4 | Ifosfamide Pathway, Pharmacokinetics | | | 5 | Citalopram Pathway, Pharmacokinetics | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ABCC10
3  PharmGKB Pathways for ABCC10
1 
Kegg Pathway (Kegg details for ABCC10):
ABCC10 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ABCC10
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ABCC10 (ENSP000002445334) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0055085 | transmembrane transport |
TAS | -- |
ABCC10 for ontologies About GeneDecksing
|
Drugs & Compounds
for ABCC10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ABCC10 for compounds About GeneDecksing
 Browse Tocris compounds for ABCC10
10/14 DrugBank Compounds for ABCC10 (see all 14) About this table
4 Novoseek chemical compound relationships for ABCC10 gene About this table
1 PharmGKB related drug/compound annotation for ABCC10 geneAbout this table
Search CenterWatch for drugs/clinical trials and news about ABCC10 / MRP7
|
Transcripts
for ABCC10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABCC10 gene (2 alternative transcripts): NM_001198934.1 NM_033450.2 Unigene Cluster for ABCC10: ATP-binding cassette, sub-family C (CFTR/MRP), member 10 Hs.55879 [show with all ESTs]Unigene Representative Sequence: NM_03345011 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372515 ENST00000502549 ENST00000372530(uc003ouy.1) ENST00000443426
ENST00000244533(uc003ouz.1) ENST00000463024(uc010jyo.1) ENST00000469856
ENST00000372512 ENST00000437104 ENST00000443394 ENST00000505344
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCC10 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCC10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ABCC10 (NM_033450) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCC10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCC10 |
Additional cDNA sequence: AK000002.1 AK024446.1 AL122095.1 AL133613.1 AY032599.1 BC024103.1 14 DOTS entries: DT.411217 DT.121405800 DT.100785771 DT.205330 DT.100785775 DT.100785772 DT.101971906 DT.95191036 DT.100678325 DT.102842105 DT.121405582 DT.91921778 DT.97792295 DT.91989261 24/99 AceView cDNA sequences (see all 99): AK000002 BQ927118 BM352750 AL133613 AL122095 BX295257 BQ101068 BU856523 AK024446 AA872614 CK823092 AI279844 CR598420 BE504183 BU557035 BQ101051 NM_033450 BC024103 BU553425 BG757898 BG758292 BQ686840 BQ002433 BU856287
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ABCC10 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18b | · | 18c | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ABCC10
|
Expression
for ABCC10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCC10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ABCC10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABCC10
SOURCE GeneReport for Unigene cluster: Hs.55879
UniProtKB/Swiss-Prot: MRP7_HUMAN, Q5T3U5Tissue specificity: Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed
SABiosciences Expression via Pathway-Focused PCR Array including ABCC10:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCC10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCC10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCC10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCC10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCC10 |
Orthologs
for ABCC10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ABCC10 gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ABCC101 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 10 less |
64.39(n)
62.74(a) |
|
421456 XM_419506.3 XP_419506.3 |
lizard
(Anolis carolinensis) |
Reptilia |
ABCC106 |
-- |
60(a) |
1 ↔ 1 |
1(231265368-231287919) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.166182 |
Transcribed sequence with weak similarity to protein pirT43469 (H.sapiens) T43469 hypothetical protein DKFZp434L0827.1 - human (fragment) less |
77.46(n) |
|
57094294 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG78061 |
CG7806 |
47.09(n)
39.56(a) |
|
34140 NM_135363.2 NP_609207.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
MRP111 |
multidrug resistance-associated protein 11 |
46.02(n)
39.55(a) |
|
815414 NM_126770.7 NP_178811.7 |
ENSEMBL Gene Tree for ABCC10 (if available)
TreeFam Gene Tree for ABCC10 (if available) |
Paralogs
for ABCC10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABCC10 gene
- ABCC42 ABCC122 ABCC12 CFTR2 ABCC82 ABCC52 ABCC32 ABCC62
- ABCC22 ABCC112 ABCC92
18/25 SIMAP similar genes for ABCC10 using alignment to 4 protein entries: MRP7_HUMAN (see all proteins)
(see all similar genes):DKFZp434I2115 NG-TRA ABCB4 CFTR ABCC1 TAP1
ABCB5 ABCC9 DKFZp781G125 MOAT-B mrp 7 ABCC2
ara ABCB9 ABCC4 ABCC3 TAP2 MRP3
ABCC10 for paralogs About GeneDecksing
|
Genomic Variants
for ABCC10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCC10 (43395104 - 43418168 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ABCC10: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCC10 |
|
Disorders
/ Diseases
for ABCC10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCC10 for disorders About GeneDecksing
OMIM gene information: 612509
OMIM disorders: --
4  diseases for ABCC10: About MalaCardslung cancer adenocarcinoma cftr-related disorders was-related disorders
1 Novoseek disease relationship for ABCC10 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cancer |
11.4 |
3 |
19841739 (1) |
Human Genome Epidemiology (HuGE) Navigator: ABCC10 (1 document)
Export disorders for ABCC10 gene to outside databases
|
Publications
for ABCC10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCC10 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with ABCC10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10). (PubMed id 12527806)1, 2, 7 Chen Z.-S....Kruh G.D. (2003)
- Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B. (PubMed id 19118001)1, 7, 9 Hopper-Borge E....Kruh G.D. (2009)
- Genomic structure, gene expression, and promoter analysis of human multidrug resistance-associated protein 7. (PubMed id 12566991)1, 2, 9 Kao H.-H.... Huang J.-D. (2003)
- Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance. (PubMed id 19150344)1, 7, 9 Zhou Y....Chen Z.S. (2009)
- Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel. (PubMed id 15256465)1, 2, 9 Hopper-Borge E.... Kruh G.D. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1, 3 Allikmets R....Dean M. (1996)
- Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily. (PubMed id 11146224)1, 9 Hopper E....Kruh G.D. (2001)
- Imatinib and nilotinib reverse multidrug resistance i n cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10). (PubMed id 19841739)1, 9 Shen T....Chen Z.S. (2009)
- Multidrug resistance-associated protein 7 expression is involved in cross-resistance to docetaxel in salivary gland adenocarcinoma cell lines. (PubMed id 17203221)1, 9 Naramoto H....Furusawa K. (2007)
|
External Searches for ABCC10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ABCC10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCC10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABCC10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ABCC10 | Pharmacogenomics, SNPs, Pathways | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q5T3U5 |
|
| | |
About This Section
| Patent Information for ABCC10 gene:
Search GeneIP for patents involving ABCC10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ABCC10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ABCC10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCC10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCC10 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABCC10 | | OriGene 3'-UTR Clone for ABCC10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCC10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCC10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABCC10 | | OriGene Custom Protein Services for ABCC10 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCC10 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCC10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCC10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCC10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCC10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCC10 |
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| | | | Search Tocris compounds for ABCC10 |
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 | | | ABCC10 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCC10 |
|  |  |  | | | | ThermoFisher Antibody for ABCC10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCC10 |
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