Aliases for ABCC10 Gene
External Ids for ABCC10 Gene
Previous GeneCards Identifiers for ABCC10 Gene
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
GeneCards Summary for ABCC10 Gene
ABCC10 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10) is a Protein Coding gene. Diseases associated with ABCC10 include congenital bilateral absence of vas deferens and bronchiectasis with or without elevated sweat chloride 1. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Tenofovir/Adefovir Pathway, Pharmacokinetics. GO annotations related to this gene include ATPase activity and ATPase activity, coupled to transmembrane movement of substances.
UniProtKB/Swiss-Prot for ABCC10 Gene
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.