ABCB8 Gene
protein-coding GIFtS: 60
GCID: GC07P150725
|
|
ATP-binding cassette, sub-family B (MDR/TAP), member 8
| |
Aliases
for ABCB8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 81 2 | | Mitochondrial ATP-Binding Cassette 12 3 | | MABC11 2 3 5 | | ATP-Binding Cassette Sub-Family B Member 8, Mitochondrial2 | | M-ABC11 2 3 | | Mitochondrial ABC Protein2 | | EST3281281 2 | | EC 3.6.38 |
Export aliases for ABCB8 gene to outside databasesPrevious GC identifers: GC07P148972 GC07P150040 GC07P150117 GC07P150164 GC07P150356 GC07P144537 |
Summaries
for ABCB8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABCB8:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes aredivided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of theMDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigenpresentation. The function of this half-transporter has not yet been determined; however, it may involve thecompartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol.This protein may also play a role in the transport of phospholipids into mitochondrial membranes. (provided by RefSeq,Jul 2008)
Gene Wiki entry for ABCB8
|
Genomic Views
for ABCB8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABCB8 gene promoter:
USF1 Lmo2 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 Arnt E47 AREB6 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCB8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCB8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q36 Ensembl cytogenetic band: 7q36.1 HGNC cytogenetic band: 7q36.1ABCB8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P150725: view genomic region
(about GC identifiers)
Start:
|
150,725,510 bp from pter |
End:
|
150,744,869 bp from pter |
Size:
|
19,360 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 150,055,049-150,074,408 |
|
Proteins
for ABCB8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ABCB8_HUMAN, Q9NUT2 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family B member 8, mitochondrial precursor Size: 735 amino acids; 79989 Da
Subunit: Monomer (Potential)
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Secondary accessions: B2RBL8 O95787 Q53GM0Alternative splicing: 2 isoforms: Q9NUT2-1 Q9NUT2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ABCB8: NX_Q9NUT2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NUT2
2 DME Specific Peptides for ABCB8 (Q9NUT2)
ABCB8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_009119.2
ENSEMBL proteins: ENSP00000417563 ENSP00000351717 ENSP00000419014 ENSP00000418970 ENSP00000420216 ENSP00000297504 ENSP00000420631 ENSP00000418271 ENSP00000419891 ENSP00000419558 ENSP00000418316 ENSP00000420162 ENSP00000438776 ENSP00000348353 Reactome Protein details: Q9NUT2
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
ABCB8 for ontologies About GeneDecksing
ABCB8 Antibody Products:
Assay Products for ABCB8: |
Protein
Domains /
Families
for ABCB8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCB8 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9NUT2ProtoNet protein and cluster: Q9NUT2 UniProtKB/Swiss-Prot: ABCB8_HUMAN, Q9NUT2Similarity: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201)subfamilySimilarity: Contains 1 ABC transmembrane type-1 domainSimilarity: Contains 1 ABC transporter domain |
Function
for ABCB8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
Genatlas biochemistry entry for ABCB8:ATP binding cassette superfamily,subfamily B (MDR/TAP),member 8,ubiquitously expressed,located in mitochondrial innermembrane
Enzyme Number (IUBMB): EC 3.6.32
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ABCB8 (NM_007188) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCB8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCB8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCB8 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005215 | transporter activity |
TAS | 9878413 | | GO:0005524 | ATP binding |
IEA | -- | | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances |
IBA | -- |
ABCB8 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ABCB8:
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Abcb8):
ABCB8 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ABCB8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | Mitochondrial ABC transporters | | | 3 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for ABCB8
1 
Kegg Pathway (Kegg details for ABCB8):
ABCB8 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABCB8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/9 Interacting proteins for ABCB8 (Q9NUT22, 3 ENSP000003517174) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
ABCB8 for ontologies About GeneDecksing
|
Drugs & Compounds
for ABCB8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ABCB8
1 DrugBank Compound for ABCB8 About this table
Search CenterWatch for drugs/clinical trials and news about ABCB8
|
Transcripts
for ABCB8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABCB8 gene: NM_007188.3 Unigene Cluster for ABCB8: ATP-binding cassette, sub-family B (MDR/TAP), member 8 Hs.647118 [show with all ESTs]Unigene Representative Sequence: NM_00718818/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000461373 ENST00000358849(uc003wil.4 uc010lpx.3 uc011kvd.2 uc003wim.4 uc003wik.4)
ENST00000482309 ENST00000488826 ENST00000489192 ENST00000471796 ENST00000462605
ENST00000466956 ENST00000470645(uc010lpw.1) ENST00000297504 ENST00000466514
ENST00000498578 ENST00000477719 ENST00000477092 ENST00000472698 ENST00000488370
ENST00000488551 ENST00000469410
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ABCB8 (NM_007188) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCB8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCB8 |
Additional cDNA sequence: AF047690.1 AF086382.1 AK002018.1 AK024401.1 AK094005.1 AK094636.1 AK222911.1 AK294344.1 AK310796.1 AK314721.1 AL117497.1 BC141814.1 BC141836.1 BC151235.1 U66688.1 21 DOTS entries: DT.100795794 DT.310230 DT.112092 DT.100795799 DT.101984506 DT.91750226 DT.100795798 DT.121101666 DT.95376252 DT.100028068 DT.100795797 DT.92426830 DT.121101698 DT.100795791 DT.102831874 DT.121101754 DT.102831873 DT.121101669 DT.121101676 DT.121101688 DT.121101685 24/204 AceView cDNA sequences (see all 204): BC030282 AW960651 AL046680 BQ223720 AA309016 BM552265 CA395398 BU155892 AK126885 BQ676865 AK024401 CR592221 CA944727 BU527147 BQ718758 BI490066 AA825988 AI420480 BQ678344 AF195024 BM664643 CR616094 BU625433 AK094636
GeneLoc Exon Structure
5/27 Alternative Splicing Database (ASD) splice patterns (SP) for ABCB8 (see all 27) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | - | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ | 23a | · | 23b | · | 23c | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 24 | ^ | 25 | ^ | 26 | ^ | 27a | · | 27b | ^ | 28a | · | 28b | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32a | · | 32b | · | 32c |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for ABCB8
|
Expression
for ABCB8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCB8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ABCB8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABCB8
SOURCE GeneReport for Unigene cluster: Hs.647118
UniProtKB/Swiss-Prot: ABCB8_HUMAN, Q9NUT2Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for ABCB8
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCB8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCB8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCB8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCB8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCB8 |
Orthologs
for ABCB8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ABCB8 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
ABCB86 |
-- |
64(a) |
1 ↔ 1 |
GL343907.1(112549-128459) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.184752 |
Transcribed sequence with moderate similarity to protein more |
74.02(n) |
|
BG303035.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG102263
CG18241 |
multidrug transporter3
CG18241 |
54(a)
(best of 2)3
56.88(n)1
53.19(a)1 |
|
65A103
322081 NM_132582.21 NP_572810.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
haf-61 |
Protein HAF-6 |
53.78(n)
51.3(a) |
|
171694 NM_058427.4 NP_490828.3 |
Alicante grape
(Vitis vinifera) |
eudicotyledons |
Vvi.63722 |
Vitis vinifera transcribed sequence with moderate similarity more |
68.98(n) |
|
CB979583.1 |
barley
(Hordeum vulgare) |
Liliopsida |
AB063580.12 |
-- |
73.12(n) |
|
AB063580.1 |
ENSEMBL Gene Tree for ABCB8 (if available)
TreeFam Gene Tree for ABCB8 (if available) |
Paralogs
for ABCB8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABCB8 gene
- TAP22 ENSG000002502642 ABCB102 TAP12 ABCB92
16 SIMAP similar genes for ABCB8 using alignment to 13 protein entries: ABCB8_HUMAN (see all proteins):ABCB4 NG-TRA TAP1 MDR1 ABCB10 TAP2-G
ABCB1 DKFZp434I2115 ABCB11 ABCB9 TAP2 ABCB5
ABCG2 ABCB6 ABC-transporter ABCB3
ABCB8 for paralogs About GeneDecksing
|
Genomic Variants
for ABCB8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCB8 (150725510 - 150744869 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ABCB8
1 CNV: 4574 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ABCB8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCB8 for disorders About GeneDecksing
OMIM gene information: 605464
OMIM disorders: --
7  diseases for ABCB8: About MalaCardsacute myeloid leukemia myeloid leukemia leukemia pneumonia
tuberculosis melanoma mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: ABCB8 (6 documents)
Export disorders for ABCB8 gene to outside databases
|
Publications
for ABCB8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCB8 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with ABCB8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of a mammalian mitochondrial ATP- binding cassette membrane protein. (PubMed id 9878413)1, 2, 9 Hogue D.L.... Ling V. (1999)
- ABCB8 mediates doxorubicin resistance in melanoma cells by protecting the mitochondrial genome. (PubMed id 19147539)1, 7 Elliott A.M. and Al-Hajj M.A. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population. (PubMed id 11829140)1, 2 Saito S.... Nakamura Y. (2002)
- Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1, 3 Allikmets R....Dean M. (1996)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
|
External Searches for ABCB8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing ABCB8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ABCB8 gene
(According to HUGE)
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Specialized Databases showing ABCB8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ABCB8 | Pharmacogenomics, SNPs, Pathways | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q9NUT2 |
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| Patent Information for ABCB8 gene:
Search GeneIP for patents involving ABCB8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ABCB8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for ABCB8 | | OriGene shRNA RFP for ABCB8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCB8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCB8 | | | OriGene Protein Over-expression Lysate for ABCB8 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABCB8 | | OriGene 3'-UTR Clone for ABCB8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABCB8 | | OriGene Custom Protein Services for ABCB8 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCB8 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCB8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCB8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCB8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCB8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCB8 |
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| | | | Search Tocris compounds for ABCB8 |
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 | | | ABCB8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCB8 |
|  |  |  | | | | ThermoFisher Antibodies for ABCB8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCB8 |
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