ABCB5 Gene
protein-coding GIFtS: 57
GCID: GC07P020653
|
|
ATP-binding cassette, sub-family B (MDR/TAP), member 5
| |
Aliases
for ABCB5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 51 2 | | P-Glycoprotein ABCB52 3 | | ABCB5alpha1 2 | | ATP-Binding Cassette Protein2 | | ABCB5beta1 2 | | ATP-Binding Cassette Sub-Family B Member 52 | | EST4225621 2 | | EC 3.6.38 | | ABCB5 P-Gp2 3 | | EC 3.6.3.448 |
Export aliases for ABCB5 gene to outside databasesPrevious GC identifers: GC07U990157 GC07P020328 GC07P020431 GC07P020412 GC07P020460 GC07P020544 |
Summaries
for ABCB5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABCB5:
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteinsparticipate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions,sugars, and peptides to more complex organic molecules (Chen et al., 2005 (PubMed 15760339)).(supplied by OMIM, Mar2008)
UniProtKB/Swiss-Prot: ABCB5_HUMAN, Q2M3G0Function: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeuticdrug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas
Gene Wiki entry for ABCB5
|
Genomic Views
for ABCB5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABCB5 gene promoter:
Nkx3-1 TBP Nkx3-1 v4 Nkx3-1 v1 Nkx2-5 HNF-3beta YY1 Nkx3-1 v2 Nkx3-1 v3 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCB5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCB5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p21.1 Ensembl cytogenetic band: 7p21.1 HGNC cytogenetic band: 7p14ABCB5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P020653: view genomic region
(about GC identifiers)
Start:
|
20,654,830 bp from pter |
End:
|
20,816,658 bp from pter |
Size:
|
161,829 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 20,706,592-20,847,927 |
|
Proteins
for ABCB5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ABCB5_HUMAN, Q2M3G0 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family B member 5 Size: 812 amino acids; 89832 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Miscellaneous: Depletion of ABCB5 by RNAi increases the sensitivity to several drugs of a subset of melanoma cells
Caution: Was named ABCB1 by some authors
Sequence caution: Sequence=AAN76500.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAQ03033.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A4D131 B5MD19 B7WPL1 F8QQP8 Q2M3I5 Q5I5Q7 Q5I5Q8 Q6KG50 Q6XFQ5 Q8IXA1Alternative splicing: 3 isoforms: Q2M3G0-1 Q2M3G0-2 Q2M3G0-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ABCB5: NX_Q2M3G0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q2M3G0
4/8 DME Specific Peptides for ABCB5 (Q2M3G0) (see all 8)
ABCB5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001157413.1 NP_001157414.1 NP_001157465.1 NP_848654.3
ENSEMBL proteins: ENSP00000384881 ENSP00000406730 ENSP00000383899 ENSP00000258738 ENSP00000398692 Reactome Protein details: Q2M3G0
Human Recombinant Protein Products for ABCB5:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
ABCB5 for ontologies About GeneDecksing
ABCB5 Antibody Products:
Assay Products for ABCB5: |
Protein
Domains /
Families
for ABCB5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCB5 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q2M3G0ProtoNet protein and cluster: Q2M3G0 UniProtKB/Swiss-Prot: ABCB5_HUMAN, Q2M3G0Similarity: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201)subfamilySimilarity: Contains 1 ABC transmembrane type-1 domainSimilarity: Contains 2 ABC transporter domains |
Function
for ABCB5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ABCB5_HUMAN, Q2M3G0Function: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeuticdrug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas Genatlas biochemistry entry for ABCB5:ATP binding cassette superfamily,subfamily B (MDR/TAP),member 5,ubiquitously expressed
Enzyme Numbers (IUBMB): EC 3.6.3.442 EC 3.6.32
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005524 | ATP binding |
IEA | -- | | GO:0015562 | efflux transmembrane transporter activity |
IDA | 12960149 | | GO:0016887 | ATPase activity |
-- | -- | | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances |
IBA | -- |
ABCB5 for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for ABCB5:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB5 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB5 (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): ABCB5 (NM_178559) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCB5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCB5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCB5 |
|
Pathways & Interactions
for ABCB5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ABCB5
1 
Kegg Pathway (Kegg details for ABCB5):
ABCB5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABCB5
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for ABCB5 (Q2M3G03 ENSP000002587384) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
ABCB5 for ontologies About GeneDecksing
|
Drugs & Compounds
for ABCB5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ABCB5
Search CenterWatch for drugs/clinical trials and news about ABCB5
|
Transcripts
for ABCB5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABCB5 gene (4 alternative transcripts): NM_001163941.1 NM_001163942.1 NM_001163993.1 NM_178559.5 Unigene Cluster for ABCB5: ATP-binding cassette, sub-family B (MDR/TAP), member 5 Hs.404102 [show with all ESTs]Unigene Representative Sequence: NM_0011639416 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000404938(uc010kuh.3 uc003suw.4) ENST00000477094 ENST00000443026(uc003suv.4)
ENST00000406935(uc011jyi.1) ENST00000258738(uc003sux.1) ENST00000441315
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB5 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB5 (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ABCB5 (NM_178559) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCB5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCB5 |
Additional cDNA sequence: AB353947.1 AF319622.1 AF399931.1 AK127141.1 AY090613.1 AY230001.1 AY234788.1 AY785909.1 AY851364.1 AY851365.1 BC044248.1 BC104894.1 BC104920.1 BC110370.1 BX537763.1 GU437216.1 GU437217.1 U66692.1 10 DOTS entries: DT.99941473 DT.320703 DT.108191 DT.121059155 DT.121059165 DT.101958082 DT.108190 DT.101970870 DT.201506 DT.40307081 24/29 AceView cDNA sequences (see all 29): AA243820 AL040762 AK127141 AY234788 AY090613 NM_178559 H98200 CR595059 AF399931 BX452500 BC044248 BM926413 BM471690 AI289916 N43802 BM016204 AF319622 AL040763 AL040717 BX537763 BX463401 BM013981 N24315 H98201
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ABCB5 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ABCB5
|
Expression
for ABCB5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCB5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ABCB5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABCB5
SOURCE GeneReport for Unigene cluster: Hs.404102
UniProtKB/Swiss-Prot: ABCB5_HUMAN, Q2M3G0Tissue specificity: Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level).Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues
SABiosciences Expression via Pathway-Focused PCR Array including ABCB5:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCB5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCB5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCB5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCB5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCB5 |
Orthologs
for ABCB5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ABCB5 gene from 5/22 species (see all 22) About this table
ENSEMBL Gene Tree for ABCB5 (if available)
TreeFam Gene Tree for ABCB5 (if available) |
Paralogs
for ABCB5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABCB5 gene
- ABCB12 ABCB42 ABCB112
17 SIMAP similar genes for ABCB5 using alignment to 6 protein entries: ABCB5_HUMAN (see all proteins):TAP1 LOC402251 ABCB1 MDR3 ABCB4 ABCB11
NG-TRA MDR1 ABCB9 ABCC10 DKFZp434I2115 TAP2-G
ABCB10 CFTR TAP2 ABCB8 ABCG2
ABCB5 for paralogs About GeneDecksing
|
Genomic Variants
for ABCB5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCB5 (20654830 - 20816658 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for ABCB5
10 CNVs: 52189 37451 94404 36657 64773 99887 99888 39490 52190 44300
1 Indel: 47318 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCB5 |
|
Disorders
/ Diseases
for ABCB5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCB5 for disorders About GeneDecksing
OMIM gene information: 611785
OMIM disorders: --
10  diseases for ABCB5: About MalaCardscrohn's disease liver cancer pancreatic cancer colorectal cancer
pancreatitis obesity melanoma malaria
leukemia neuronitis
1 disease from the University of Copenhagen DISEASES database for ABCB5:Melanoma Human Genome Epidemiology (HuGE) Navigator: ABCB5 (1 document)
Export disorders for ABCB5 gene to outside databases
|
Publications
for ABCB5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCB5 gene, integrated from 9 sources (see all 29):
(articles sorted by number of sources associating them with ABCB5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter. (PubMed id 12960149)1, 2, 3 Frank N.Y....Frank M.H. (2003)
- ABCB5 Identifies a Therapy-Refractory Tumor Cell Popu lation in Colorectal Cancer Patients. (PubMed id 21652540)1, 2 Wilson B.J....Frank N.Y. (2011)
- Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes. (PubMed id 15760339)1, 2 Chen K.G....Gottesman M.M. (2005)
- ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. (PubMed id 15899824)1, 2 Frank N.Y.... Frank M.H. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. (PubMed id 15205344)1, 2 Huang Y.... Sadee W. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1, 3 Allikmets R....Dean M. (1996)
- The helicase HAGE expressed by malignant melanoma-init iating cells is required for tumor cell proliferation in vivo. (PubMed id 22393060)1 Linley A.J....Regad T. (2012)
- Profiling of ABC transporters ABCB5, ABCF2 and nestin- positive stem cells in nevi, in situ and invasive melanoma. (PubMed id 22555176)1 Setia N....Mahalingam M. (2012)
|
External Searches for ABCB5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ABCB5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCB5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ABCB5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ABCB5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ABCB5 gene:
Search GeneIP for patents involving ABCB5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ABCB5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ABCB5 | | OriGene shRNA RFP for ABCB5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCB5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCB5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABCB5 | | OriGene 3'-UTR Clone for ABCB5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCB5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABCB5 | | OriGene Custom Protein Services for ABCB5 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCB5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCB5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCB5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCB5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCB5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCB5 |
| |
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| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCB5 |
|  |  |  |  | | | | ThermoFisher Antibodies for ABCB5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCB5 |
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