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ABCA9 Gene

protein-coding   GIFtS: 55
GCID: GC17M066970

ATP-Binding Cassette, Sub-Family A (ABC1), Member 9

  Search for ABCA9
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATP-Binding Cassette, Sub-Family A (ABC1), Member 91 2
EST6409182
ATP-Binding Cassette A92
ATP-Binding Cassette Sub-Family A Member 92
EC 3.6.38
EC 3.6.3.418

External Ids:    HGNC: 391   Entrez Gene: 103502   Ensembl: ENSG000001542587   OMIM: 6125075   UniProtKB: Q8IUA73   

Export aliases for ABCA9 gene to outside databases

Previous GC identifers: GC17M066770 GC17M069931 GC17M067435 GC17M067568 GC17M064482 GC17M062357


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ABCA9 Gene:
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein
contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules
across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP,
MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other
ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte
differentiation into macrophages and is suppressed by cholesterol import. (provided by RefSeq, Jul 2008)

GeneCards Summary for ABCA9 Gene:
ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a protein-coding gene. GO annotations related to this gene include ATPase activity. An important paralog of this gene is ABCA1.

UniProtKB/Swiss-Prot: ABCA9_HUMAN, Q8IUA7
Function: May play a role in monocyte differentiation and lipid homeostasis

Gene Wiki entry for ABCA9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ABCA9 gene promoter:
         c-Fos   NF-1   AP-1   JunB   FosB   Fra-1   MEF-2A   JunD   aMEF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABCA9 promoter sequence
   Search Chromatin IP Primers for ABCA9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ABCA9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q24.2   Ensembl cytogenetic band:  17q24.2   HGNC cytogenetic band: 17q24

ABCA9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABCA9 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M066970:  view genomic region     (about GC identifiers)

Start:
66,970,629 bp from pter      End:
67,057,205 bp from pter
Size:
86,577 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ABCA9_HUMAN, Q8IUA7 (See protein sequence)
Recommended Name: ATP-binding cassette sub-family A member 9  
Size: 1624 amino acids; 184362 Da
Developmental stage: Expressed in fetal tissues with higher expression in fetal heart and kidney
Sequence caution: Sequence=AAH62472.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC11021.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6P655 Q8N2S4 Q8WWZ5 Q96MD8
Alternative splicing: 5 isoforms:  Q8IUA7-1   Q8IUA7-2   Q8IUA7-3   Q8IUA7-4   Q8IUA7-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ABCA9: NX_Q8IUA7

Explore proteomics data for ABCA9 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn120, Asn195, Asn949
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ABCA9 (Q8IUA7) (see all 5)
     VLLLDEP  LDEPTAG  NGAGKST  DEPTAGLD 


    See ABCA9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_525022.2  
    ENSEMBL proteins: 
     ENSP00000342216   ENSP00000394264   ENSP00000465601   ENSP00000465191   ENSP00000359767  
    Reactome Protein details: Q8IUA7

    ABCA9 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ABCA9

     
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    Search eBioscience for ELISAs for ABCA9 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ABCA: ATP binding cassette transporters / subfamily A

    IUPHAR Guide to PHARMACOLOGY protein family classification: ABCA9
    ABCA subfamily

    4 InterPro protein domains:
     IPR003439 ABC_transporter-like
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase
     IPR026082 ABC_A

    Graphical View of Domain Structure for InterPro Entry Q8IUA7

    ProtoNet protein and cluster: Q8IUA7

    UniProtKB/Swiss-Prot: ABCA9_HUMAN, Q8IUA7
    Similarity: Belongs to the ABC transporter superfamily. ABCA family
    Similarity: Contains 2 ABC transporter domains


    Find genes that share domains with ABCA9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABCA9_HUMAN, Q8IUA7
    Function: May play a role in monocyte differentiation and lipid homeostasis
    Induction: Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of
    macrophages

         Enzyme Numbers (IUBMB): EC 3.6.3.412 EC 3.6.32

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity IEA--
    GO:0017111nucleoside-triphosphatase activity ----
         
    Find genes that share ontologies with ABCA9           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ABCA9
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ABCA9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ABCA9
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ABCA9

    miRNA
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    Block miRNA regulation of human, mouse, rat ABCA9 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ABCA9:
    hsa-miR-3163 hsa-miR-374b hsa-miR-3919 hsa-miR-374a hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidABCA9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ABCA9

    Gene Editing
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ABCA9 (NM_080283)
    Sino Biological Human cDNA Clone for ABCA9
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABCA9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA9

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCA9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABCA9_HUMAN, Q8IUA7: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    mitochondrion2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ABCA9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ABCA9 About    
    See pathways by source

    SuperPathContained pathways About
    1ABC-family proteins mediated transport
    ABC-family proteins mediated transport0.69
    ABCA transporters in lipid homeostasis0.00
    ABC transporters0.69
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Transmembrane transport of small molecules0.47


    Find genes that share SuperPaths with ABCA9           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for ABCA9
        ABCA transporters in lipid homeostasis


    1 Kegg Pathway  (Kegg details for ABCA9):
        ABC transporters

        Pathway & Disease-focused RT2 Profiler PCR Array including ABCA9: 
              Drug Transporters in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for ABCA9

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for ABCA9 (Q8IUA73 ENSP000003422164) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    DEDDO756183I2D: score=1 
    ABCG2ENSP000002376124STRING: ENSP00000237612
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--

    Find genes that share ontologies with ABCA9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ABCA9



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ABCA9 gene (2 alternative transcripts): 
    NM_080283.3  NM_172386.1  

    Unigene Cluster for ABCA9:

    ATP-binding cassette, sub-family A (ABC1), member 9
    Hs.131686  [show with all ESTs]
    Unigene Representative Sequence: NM_080283
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340001(uc010dez.3 uc002jhu.3) ENST00000453985 ENST00000482072
    ENST00000460872 ENST00000492580 ENST00000461623 ENST00000495634(uc002jhv.3)
    ENST00000585714 ENST00000370732
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate ABCA9:
    hsa-miR-3163 hsa-miR-374b hsa-miR-3919 hsa-miR-374a hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidABCA9 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ABCA9
    Predesigned siRNA for gene silencing in human, mouse, rat ABCA9
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ABCA9 (NM_080283)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABCA9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA9
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ABCA9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ABCA9
      QuantiTect SYBR Green Assays in human, mouse, rat ABCA9
      QuantiFast Probe-based Assays in human, mouse, rat ABCA9

    Additional mRNA sequence: 

    AF423307.1 AK057068.1 AK074491.1 AK122687.1 AL833712.1 AY028899.1 BC062472.1 CR627382.1 

    9 DOTS entries:

    DT.75117570  DT.410492  DT.100027018  DT.410491  DT.100704618  DT.75153861  DT.100736998  DT.120986999 
    DT.75122701 

    Selected AceView cDNA sequences (see all 57):

    BX280456 AF423307 BC062472 AI627862 BM992857 AL698804 BX281489 AI372047 
    NM_172386 NM_080283 F00423 AI446543 W84726 AK074491 CR627382 AY028899 
    BX500952 BU072174 AK057068 BU076154 AK122687 AW296945 BX496612 AI640540 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ABCA9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ABCA9 Expression
    About this image


    ABCA9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
     
     Epithelial Cells
             Podocytes Podocyte Layer
     
     Ovary (Reproductive System)
             Pre-Granulosa Cells Primordial Follicle
     
     Kidney (Urinary System)
             Podocytes Podocyte Layer
     
     Blood (Cardiovascular System)
             Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
    ABCA9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ABCA9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.131686

    UniProtKB/Swiss-Prot: ABCA9_HUMAN, Q8IUA7
    Tissue specificity: Widely expressed with higher expression in heart

        Pathway & Disease-focused RT2 Profiler PCR Array including ABCA9: 
              Drug Transporters in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCA9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ABCA9 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Abca91 , 5 ATP-binding cassette, sub-family A (ABC1), member 91, 5 81.55(n)1
    78.67(a)1
      11 (73.22 cM)5
    2172621  NM_147220.21  NP_671753.21 
     1101007495 
    chicken
    (Gallus gallus)
    Aves --
    --
    Uncharacterized protein
    51(a)
    46(a)
    many ↔ many
    many ↔ many
    18(8206967-8226132)
    18(8181915-8205387)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    45(a)
    1 → many
    GL343630.1(35018-149208)
    zebrafish
    (Danio rerio)
    Actinopterygii abch16
    ATP-binding cassette, sub-family H, member 1
    17(a)
    many ↔ many
    17(24365342-24392834) ENSDARG00000071341
    fruit fly
    (Drosophila melanogaster)
    Insecta CG312136
    --
    19(a)
    many ↔ many
    3R(15799235-15804734)
    worm
    (Caenorhabditis elegans)
    Secernentea ced-76
    Protein CED-7, isoform d
    19(a)
    many ↔ many
    III(9570216-9579873) WBGene00000421


    ENSEMBL Gene Tree for ABCA9 (if available)
    TreeFam Gene Tree for ABCA9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ABCA9 gene
    ABCA12  ABCA102  ABCA132  ABCA32  ABCA82  ABCA122  ABCA42  ABCA72  
    ABCA22  ABCA62  ABCA52  
    14 SIMAP similar genes for ABCA9 using alignment to 3 protein entries:     ABCA9_HUMAN (see all proteins):
    DKFZp686F2450    ABCA8    ABCA10    ABCA6    DKFZp686K07118    ABCA13
    ABCA2    ABCA11P    ABCA5    DKFZp547P193    ABC2    ABCG2
    ABCA4    DKFZp434E1030

    Find genes that share paralogs with ABCA9           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ABCA9
    PGOHUM00000248883


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ABCA9 (see all 2018)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1509667491,2
    --66970294(+) ATTGAC/TACTTT 1 -- ds50010--------
    rs80728101,2
    C,F,H--66970336(+) GTCTGA/TGTGTG 1 -- ds50016Minor allele frequency- T:0.05NS EA WA 518
    rs1394977701,2
    --66970349(+) ATTAGC/TGCGGA 1 -- ds50010--------
    rs80775041,2
    C,F,A,H--66970369(+) TCTTAT/CAAAAT 1 -- ds500117Minor allele frequency- C:0.25NS EA NA WA CSA 2081
    rs1496730531,2
    C--66970434(+) GAAATC/TTGGCT 1 -- ds50010--------
    rs1454379861,2
    --66970474(+) ATGTAC/TGTAAA 1 -- ds50010--------
    rs1857273031,2
    --66970521(+) CTCATC/TTGTGA 1 -- ds50010--------
    rs99026511,2
    C,F--66970577(+) TTTTTT/AAAAAA 1 -- ds50013Minor allele frequency- A:0.41WA 122
    rs21912131,2
    C,F,A,H--66970618(-) TTCGTA/CTGAGA 1 -- ds500113Minor allele frequency- C:0.44NS EA NA WA CSA 790
    rs1418697541,2
    --66970648(+) AAGTGG/TTTTAT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for ABCA9 (66970629 - 67057205 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ABCA9:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3246n71CNV Loss21882294
    nsv833526CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ABCA9
    DNA2.0 Custom Variant and Variant Library Synthesis for ABCA9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612507    OMIM disorders: --


    Find genes that share disorders with ABCA9           About GenesLikeMe

    Genetic Association Database (GAD): ABCA9
    Human Genome Epidemiology (HuGE) Navigator: ABCA9 (1 document)

    Export disorders for ABCA9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ABCA9 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ABCA9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9. (PubMed id 12150964)1, 2 Piehler A.... Schmitz G. (Biochem. Biophys. Res. Commun. 2002)
    5. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (J. Proteome Res. 2009)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. The human ATP-binding cassette (ABC) transporter superfamily. (PubMed id 11435397)1 Dean M....Allikmets R. (Genome Res. 2001)
    8. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1 Allikmets R....Dean M. (Hum. Mol. Genet. 1996)
    9. Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (Genome Res. 1996)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10350 HGNC: 39 AceView: ABCA9 Ensembl:ENSG00000154258 euGenes: HUgn10350
    ECgene: ABCA9 Kegg: 10350 H-InvDB: ABCA9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ABCA9 Pharmacogenomics, SNPs, Pathways
    ABCMdbhttp://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q8IUA7

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ABCA9 gene:
    Search GeneIP for patents involving ABCA9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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