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ABCA5 Gene

protein-coding GIFtS: 57

GC17M064754

ATP-binding cassette, sub-family A (ABC1), member 5
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ABC13 ^²
DKFZp451F117 ^²
DKFZp779N2435 ^²
EST90625 ^¹, ²
FLJ16381 ^²
KIAA1888 ^³, ⁵

Descriptions
ATP-binding cassette A5 ^²
ATP-binding cassette, sub-family A (ABC1), member 5 ^²
ATP-binding cassette, sub-family A , member 5 ^²
ATP-binding cassette, sub-family A, member 5 ^¹

External Ids
HGNC: 35¹
Entrez Gene: 23461²
UniProtKB: Q8WWZ7³
Ensembl: ENSG00000154265⁷

Search outside databases for aliases for ABCA5 gene

Previous GC identifers: GC17M067042 GC17M070203 GC17M067707 GC17M067839

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ABCA5:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding

cassette (ABC) transporters. ABC proteins transport various molecules across extra- and

intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP,

MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members

of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular

eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the

substrate nor the function of this gene is known. Alternative splicing of this gene results in

several transcript variants; however, not all variants have been fully described. [provided by

RefSeq]

UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7

Function: May play a role in the processing of autolysosomes (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ABCA5 gene

Entrez Gene cytogenetic band: 17q24.3 Ensembl cytogenetic band: 17q24.3 HGNC cytogenetic band: 17q21-q25

ABCA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M064754: (about GC identifiers)

Start:	64,754,386 bp from pter
End:	64,834,885 bp from pter
Size:	80,500 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000017.9 NT_010641.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7 (See protein sequence)

Recommended Name: ATP-binding cassette sub-family A member 5

Size: 1642 amino acids; 186508 Da

Subcellular location: Lysosome membrane; Multi-pass membrane protein. Late endosome membrane;

Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein (By similarity)

Developmental stage: Expressed in fetal liver, kidney and brain

Secondary accessions: Q8IVJ2 Q96LJ1 Q96MS4 Q96PZ9 Q9NY14

Alternative splicing: 3 isoforms: Q8WWZ7-1 Q8WWZ7-2 Q8WWZ7-3

Post-translational modifications:

N-glycosylated (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_061142.2 NP_758424.1

ENSEMBL proteins:

ENSP00000376444 ENSP00000319766 ENSP00000376443

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ABCA5)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/7 Gene Ontology (GO) cellular component terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IEA	--
GO:0005765	lysosomal membrane	IEA	--
GO:0005768	endosome	IEA	--
GO:0005794	Golgi apparatus	IEA	--
GO:0016020	membrane	IEA	--

About this table

Antibodies for ABCA5:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ABCA5
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ABCA5), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for ABCA5

Assays for ABCA5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8WWZ7

ProtoNet protein and cluster: Q8WWZ7

UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7

Similarity: Belongs to the ABC transporter family. ABCA subfamily

Similarity: Contains 2 ABC transporter domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ABCA5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ABCA5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_172232

Applied Biosystems Silencer® siRNAs for ABCA5

Sigma-Aldrich siRNA and siRNA Panels for ABCA5

Sigma-Aldrich shRNA for ABCA5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_018672
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_018672
untagged cDNA clones in CMV expression vector (see all 2): NM_018672

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_018672

UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7

Function: May play a role in the processing of autolysosomes (By similarity)

Genatlas biochemistry entry for ABCA5:

ATP binding cassette superfamily,subfamily A,member 5,mouse ABC4 homolog

8 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Abca5):

	behavior/neurological	endocrine/exocrine gland	homeostasis/metabolism	life span-post-weaning/aging
liver/biliary system	muscle	vision/eye

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016887	ATPase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Interacting protein for ABCA5 (ENSP00000319766³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABCA9	ENSP00000342216³	STRING (score=.726)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006810	transport	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ABCA5

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ABCA5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ABCA5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_172232

Sigma-Aldrich siRNA and siRNA Panels for ABCA5

Sigma-Aldrich shRNA for ABCA5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_018672 NM_172232

REFSEQ mRNAs for ABCA5 gene (2 alternative transcripts):

NM_018672.3 NM_172232.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_018672 NM_172232

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_018672
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_018672
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_018672

Additional cDNA sequence:

AB067475.1 AJ275973.3 AJ512612.1 AK056533.1 AK058170.1 AK094416.1 AK096664.1 AK122803.1

AK292592.1 AY028897.1 BC029426.1 BC054480.1 BC070126.1 BC146819.1 BX640746.1 BX647447.1

BX648540.1 U66672.1

18 DOTS entries:

DT.101965656 DT.100718026 DT.101984314 DT.100775117 DT.92427874 DT.40280931 DT.99971934 DT.87046995

DT.100775118 DT.100775120 DT.86835941 DT.120986894 DT.120986890 DT.120987012 DT.95163499 DT.97775229

DT.100649690 DT.92033695

24/208 AceView cDNA sequences (see all 208 ):

AB067475 AK058170 BF061307 BX280304 BG566938 CA941702 BC029426 BU686259

AL698749 BQ441353 AW189609 CD629438 CA773136 NM_172232 AW440582 BG288838

AY247065 AA988796 AI698175 AY028897 AI032927 CA773849 BX415090 AI350336

highest scoring ESTs for ABCA5:

AA889893 AI149299 AI220973 AI568925 AJ275973 AJ512612 AL712051 BC029426 BF061307 BF448717

Unigene Cluster for ABCA5:

ATP-binding cassette, sub-family A (ABC1), member 5

Hs.421474 [show with all ESTs]

Unigene Representative Sequence: NM_018672

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for ABCA5

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17a	·	17b	^	18	^	19	^	20	^	21	^	22a	·	22b	^	23	^
SP1:
SP2:																																																	-
SP3:
SP4:
SP5:					-		-

ExUns:	24	^	25	^	26	^	27	^	28	^	29	^	30	^	31	^	32	^	33	^	34	^	35	^	36	^	37	^	38	^	39	^	40	^	41a	·	41b
SP1:																											-
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for ABCA5

3 Ensembl transcripts including schematic representations:

ENST00000392677 ENST00000320086 ENST00000392676

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ABCA5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ABCA5

¹ / ² / ³

4 probe-sets matching ABCA5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
38574_at²^{, 3}	U95-A	1	1.00	1.00	0.92	0.50	U66672	0.60	1.00	0.82	1
63906_f_at²^{, 3}	U95-C	3341	0.75	0.00	0.43	1.51	R98835	0.20	0.02	0.14	1
213353_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BF693921	0.60	1.00	0.82	1
213353_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ABCA5 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TAAATAGGCA

SOURCE GeneReport for Unigene cluster: Hs.421474
Expression variation in blood from EXPOLDB for ABCA5
UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7
Tissue specificity: Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney,
liver and placenta

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ABCA5 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ABCA5¹	--	ATP-binding cassette, sub-family A (ABC1), member 5	92.73(n) 93.06(a)	480455 XM_537573.2 XP_537573.2
chimpanzee (Pan troglodytes)	ABCA5¹	--	ATP-binding cassette, sub-family A (ABC1), member 5	99.53(n) 99.03(a)	454848 XM_001166542.1 XP_001166542.1
cow (Bos taurus)	ABCA5¹	--	ATP-binding cassette, sub-family A (ABC1), member 5	85.69(n) 87.25(a)	510497 XM_587636.3 XP_587636.3
rat (Rattus norvegicus)	Abca5¹	--	ATP-binding cassette, sub-family A (ABC1), member 5	86.22(n) 90.26(a)	286970 NM_173307.1 NP_775429.1
mouse (Mus musculus)	Abca5^{1, 5}	11⁵	ATP-binding cassette, sub-family A (ABC1), member 5^{1, 5}	86.4(n)¹ 89.52(a)¹	217265¹ NM_147219.1¹ NP_671752.1¹ AB097675⁵ AF491842⁵ (see all 20)

About this table Species with no ortholog for ABCA5

ENSEMBL Gene Tree for ABCA5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ABCA5 gene

ABCA10² ABCA9² ABCA6² ABCA8²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/412 NCBI SNPs in ABCA5 are shown (see all 412 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 129)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs482529^1,2	A,C,F,H	64836594(+)	`TATCCA/CTGATA`	1	--	ng3¹ tfbs³		3		EU EA	300
	rs557491^1,2	A,C,F,H	64778912(+)	`ATGCAC/TCACAT`	2	M/V	mis¹		14		EA NA EU WA	1236
	rs536009^1,2	A,C,F,H	64785477(+)	`TAGAGA/CAGCCT`	2	A/S	mis¹ ese³		8		EU EA WA	828
	rs15886^1,2	C,F,H	64754884(+)	`TTATGA/TATTAG`	2	--	ut3¹ ese³		23		MN EA CSAM NA EU WA	3582
	rs17686569^1,2	C,F,H	64802435(+)	`TCTTCT/CGAATA`	2	R/Q	mis¹ ese³		11		NA EU EA WA	980
--	rs11650658^1,2	A,C	64824812(+)	`gcataC/Tacata`	2	--	int¹ ng3¹		0	--	--	--	--
	rs7225907^1,2	A,H	64822270(+)	`agatgG/Tattaa`	2	--	int¹ ut5¹		4		EU EA WA	408
	rs11544715^1,2	C,F	64816042(-)	`TACAAG/ACATCC`	2	T/A	mis¹		4		EU EA WA	420
	rs12383^1,2	C,H	64820858(+)	`TTTCTG/TCATGA`	2	Q/K	mis¹ ese³		9		MN EU EA WA	1016
	rs333938^1,2	A,C	64835376(+)	`GAGTCC/TTCTGC`	1	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for ABCA5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 612503

Human Genome Epidemiology Navigator: ABCA5 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/13 PubMed articles for ABCA5 gene (see all 13 ):

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant. (PubMed id 12504089)^{3, 4} Petry F.... Hirsch-Ernst K.I. (2003)
Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)^{3, 4} Nagase T....Ohara O. (2001)
Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)^{2, 3} Allikmets R....Dean M. (1996)
Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)³ Saito A....Kamatani N. (2009)
Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)³ Hosgood H.D....Lan Q. (2008)
Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor. (PubMed id 17541169)³ Ohtsuki S....Terasaki T. (2007)
The ABCA5 protein: a urine diagnostic marker for prostatic intraepithelial neoplasia. (PubMed id 17289887)³ Hu Y....Stearns M.E. (2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 23461	HGNC: 35	AceView: ABCA5andABCA10	Ensembl:ENSG00000154265	euGenes: HUgn23461
ECgene: ABCA5	H-InvDB: ABCA5

(According to HUGE)
About This Section

HUGE: KIAA1888

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for ABCA5
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ABCA5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ABCA5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ABCA5		Antibodies for ABCA5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ABCA5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

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Search OriGene for ABCA5

Search Tocris compounds for ABCA5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for ABCA5

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ABCA5 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for ABCA5

Summaries
for ABCA5

Genomic Location
for ABCA5

Proteins
for ABCA5

Protein Domains/
Families
for ABCA5

Gene Function
for ABCA5

Pathways & Interactions
for ABCA5

Drugs & Compounds
for ABCA5

Transcripts
for ABCA5

Expression
for ABCA5

Orthologs
for ABCA5

Paralogs
for ABCA5

SNPs/Variants
for ABCA5

Disorders & Mutations
for ABCA5

Medical News
for ABCA5

Publications
for ABCA5

Search for ABCA5

Genome Databases showing ABCA5

Other Databases showing ABCA5

Specialized Databases showing ABCA5

Licensable Technologies
for ABCA5

Services
for ABCA5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ABCA5 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor ABCA5

Summariesfor ABCA5

Genomic Locationfor ABCA5

Proteinsfor ABCA5

Protein Domains/Familiesfor ABCA5

Gene Functionfor ABCA5

Pathways & Interactionsfor ABCA5

Drugs & Compoundsfor ABCA5

Transcriptsfor ABCA5

Expression for ABCA5

Orthologsfor ABCA5

Paralogsfor ABCA5

SNPs/Variantsfor ABCA5

Disorders & Mutationsfor ABCA5

Medical Newsfor ABCA5

Publicationsfor ABCA5

Search for ABCA5

Genome Databases showing ABCA5

Other Databases showing ABCA5

Specialized Databases showing ABCA5

Licensable Technologiesfor ABCA5

Servicesfor ABCA5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ABCA5

Summaries
for ABCA5

Genomic Location
for ABCA5

Proteins
for ABCA5

Protein Domains/
Families
for ABCA5

Gene Function
for ABCA5

Pathways & Interactions
for ABCA5

Drugs & Compounds
for ABCA5

Transcripts
for ABCA5

Expression
for ABCA5

Orthologs
for ABCA5

Paralogs
for ABCA5

SNPs/Variants
for ABCA5

Disorders & Mutations
for ABCA5

Medical News
for ABCA5

Publications
for ABCA5

Licensable Technologies
for ABCA5

Services
for ABCA5