ABCA5 Gene
protein-coding GIFtS: 52
GCID: GC17M067240
|
|
ATP-binding cassette, sub-family A (ABC1), member 5
| |
Aliases
for ABCA5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP-Binding Cassette, Sub-Family A (ABC1), Member 51 2 | | ATP-Binding Cassette Sub-Family A Member 52 | | EST906251 2 | | EC 3.6.38 | | KIAA18883 5 | | EC 3.6.3.258 | | ABC132 | | EC 3.6.3.418 | | ATP-Binding Cassette A52 | | |
Export aliases for ABCA5 gene to outside databasesPrevious GC identifers: GC17M067042 GC17M070203 GC17M067707 GC17M067839 GC17M064754 GC17M062625 |
Summaries
for ABCA5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ABCA5:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes aredivided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is amember of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively inmulticellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substratenor the function of this gene is known. Alternative splicing of this gene results in several transcript variants;however, not all variants have been fully described. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7Function: May play a role in the processing of autolysosomes (By similarity)
|
Genomic Views
for ABCA5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ABCA5 gene promoter:
HOXA9B HOXA9 PPAR-gamma1 PPAR-gamma2 Meis-1 Evi-1 FOXL1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ABCA5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCA5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q24.3 Ensembl cytogenetic band: 17q24.3 HGNC cytogenetic band: 17q24.3ABCA5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M067240: view genomic region
(about GC identifiers)
Start:
|
67,240,452 bp from pter |
End:
|
67,323,385 bp from pter |
Size:
|
82,934 bases |
Orientation:
|
minus strand |
|
Proteins
for ABCA5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7 (See
protein sequence)Recommended Name: ATP-binding cassette sub-family A member 5 Size: 1642 amino acids; 186508 Da
Subcellular location: Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membraneprotein. Golgi apparatus membrane; Multi-pass membrane protein (By similarity)
Developmental stage: Expressed in fetal liver, kidney and brain
Sequence caution: Sequence=BAB71700.1; Type=Erroneous initiation;
Secondary accessions: Q8IVJ2 Q96LJ1 Q96MS4 Q96PZ9 Q9NY14Alternative splicing: 3 isoforms: Q8WWZ7-1 Q8WWZ7-2 Q8WWZ7-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ABCA5: NX_Q8WWZ7
Post-translational modifications:
N-glycosylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WWZ7
4/6 DME Specific Peptides for ABCA5 (Q8WWZ7) (see all 6)
ABCA5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_061142.2 NP_758424.1
ENSEMBL proteins: ENSP00000376443 ENSP00000467882 ENSP00000465766 ENSP00000467251 ENSP00000465351 ENSP00000467448 ENSP00000466931 ENSP00000467524 ENSP00000467815 ENSP00000466662 ENSP00000467672 ENSP00000376444
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
ABCA5 for ontologies About GeneDecksing
ABCA5 Antibody Products:
Assay Products for ABCA5: |
Protein
Domains /
Families
for ABCA5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ABCA5 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WWZ7ProtoNet protein and cluster: Q8WWZ7 UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7Similarity: Belongs to the ABC transporter superfamily. ABCA familySimilarity: Contains 2 ABC transporter domains |
Function
for ABCA5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7Function: May play a role in the processing of autolysosomes (By similarity) Genatlas biochemistry entry for ABCA5:ATP binding cassette superfamily,subfamily A,member 5,mouse ABC4 homolog
Enzyme Numbers (IUBMB): EC 3.6.3.412 EC 3.6.32 EC 3.6.3.252
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCA5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCA5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ABCA5 (NM_018672) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCA5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCA5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ABCA5 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Abca5tm1Akya for ABCA5
8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Abca5):
ABCA5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ABCA5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for ABCA5):
ABCA5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ABCA5
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0010745 | negative regulation of macrophage derived foam cell differentiation |
ISS | -- | | GO:0033344 | cholesterol efflux |
ISS | -- | | GO:0034375 | high-density lipoprotein particle remodeling |
ISS | -- | | GO:0043691 | reverse cholesterol transport |
IC | -- |
ABCA5 for ontologies About GeneDecksing
|
Drugs & Compounds
for ABCA5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ABCA5
1 DrugBank Compound for ABCA5 About this table
Search CenterWatch for drugs/clinical trials and news about ABCA5
|
Transcripts
for ABCA5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ABCA5 gene (2 alternative transcripts): NM_018672.3 NM_172232.2 Unigene Cluster for ABCA5: ATP-binding cassette, sub-family A (ABC1), member 5 Hs.731824 [show with all ESTs]Unigene Representative Sequence: NM_01867215 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000392676(uc002jif.2) ENST00000588877 ENST00000591234 ENST00000586995
ENST00000586601 ENST00000586811 ENST00000588106 ENST00000593153 ENST00000589975
ENST00000593253 ENST00000587607 ENST00000592568 ENST00000588665 ENST00000589609
ENST00000392677(uc002jib.2 uc002jic.2 uc002jid.2 uc002jie.2 uc002jig.2 uc002jih.2 uc010dfe.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCA5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCA5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ABCA5 (NM_018672) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ABCA5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA5 |
Additional cDNA sequence: AB067475.1 AJ275973.3 AJ512612.1 AK056533.1 AK058170.1 AK094416.1 AK096664.1 AK122803.1 AK292592.1 AY028897.1 BC029426.1 BC054480.1 BC070126.1 BC146819.1 BX640746.1 BX647447.1 BX648540.1 U66672.1 18 DOTS entries: DT.101965656 DT.100718026 DT.101984314 DT.100775117 DT.92427874 DT.99971934 DT.40280931 DT.87046995 DT.100775118 DT.100775120 DT.86835941 DT.120986894 DT.95163499 DT.97775229 DT.100649690 DT.120986890 DT.120987012 DT.92033695 24/208 AceView cDNA sequences (see all 208): BX640746 AL698749 T24994 CD629438 BQ441353 CA773136 AB067475 AI942287 AW189609 AI350336 BQ000362 NM_172232 BX280304 BF061307 CA941702 BX415090 CD629436 AI032927 AL711380 AV718464 AA988796 AJ512612 AJ275973 NM_018672
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ABCA5 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22a | · | 22b | ^ | 23 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41a | · | 41b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ABCA5
|
Expression
for ABCA5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ABCA5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAATAGGCA
About this image
See ABCA5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ABCA5
SOURCE GeneReport for Unigene cluster: Hs.731824
UniProtKB/Swiss-Prot: ABCA5_HUMAN, Q8WWZ7Tissue specificity: Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta
SABiosciences Expression via Pathway-Focused PCR Array including ABCA5: | Drug Transporters in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCA5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ABCA5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCA5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCA5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCA5 |
Orthologs
for ABCA5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ABCA5 gene from 5/21 species (see all 21) About this table
ENSEMBL Gene Tree for ABCA5 (if available)
TreeFam Gene Tree for ABCA5 (if available) |
Paralogs
for ABCA5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ABCA5 gene
- ABCG12 ABCA12 ABCA102 ABCA132 ABCA32 ABCA82 ABCG42 ABCA122
- ABCG82 ABCA42 ABCA72 ABCG52 ABCA22 ABCA92 ABCA62 ABCG22
14 SIMAP similar genes for ABCA5 using alignment to 9 protein entries: ABCA5_HUMAN (see all proteins):DKFZp686K07118 ABC2 ABCG2 ABCA10 DKFZp686F2450 ABCA6
ABCA2 ABCA8 ABCA9 DKFZp547P193 ABCA3 ABCA11P
ABCA4 DKFZp434E1030
ABCA5 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ABCA5
PGOHUM00000250826
|
Genomic Variants
for ABCA5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ABCA5 (67240452 - 67323385 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ABCA5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCA5 |
|
Disorders
/ Diseases
for ABCA5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ABCA5 for disorders About GeneDecksing
OMIM gene information: 612503
OMIM disorders: --
8  diseases for ABCA5: About MalaCardspulmonary disease pharyngitis pneumonia cholesterol
tuberculosis melanoma prostatitis mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: ABCA5 (5 documents)
Export disorders for ABCA5 gene to outside databases
|
Publications
for ABCA5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ABCA5 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with ABCA5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant. (PubMed id 12504089)1, 2 Petry F.... Hirsch-Ernst K.I. (2003)
- Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T....Ohara O. (2001)
- Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1, 3 Allikmets R....Dean M. (1996)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Identification of CBX3 and ABCA5 as putative biomarker s for tumor stem cells in osteosarcoma. (PubMed id 22870217)1 Saini V....Shoemaker R.H. (2012)
- Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1 Guey L.T....Malats N. (2010)
- ATP-binding cassette transporter ABCB5 gene is expres sed with variability in malignant melanoma. (PubMed id 20487690)1 VA!squez-Moctezuma I....Herrera-GonzA!lez N.E. (2010)
- PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1 Hosgood H.D....Lan Q. (2009)
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1 Saito A....Kamatani N. (2009)
|
External Searches for ABCA5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ABCA5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ABCA5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ABCA5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ABCA5 | Pharmacogenomics, SNPs, Pathways | | ABCMdb | http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q8WWZ7 |
|
| | |
About This Section
| Patent Information for ABCA5 gene:
Search GeneIP for patents involving ABCA5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ABCA5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ABCA5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ABCA5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ABCA5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ABCA5 | | OriGene 3'-UTR Clone for ABCA5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ABCA5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ABCA5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ABCA5 | | OriGene Custom Protein Services for ABCA5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ABCA5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ABCA5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ABCA5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ABCA5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ABCA5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ABCA5 |
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| | | | Search Tocris compounds for ABCA5 |
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 | | | ABCA5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCA5 |
|  |  |  | | | | Search ThermoFisher Antibodies for ABCA5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA5 |
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