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ABCA3 Gene

protein-coding   GIFtS: 63

GC16M002265
ATP-binding cassette, sub-family A (ABC1), member 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: ABC3)
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
ABC-C 1, 2
ABC3 2, 3, 5
EST111653 1, 2
LBM180 1, 2
MGC166979 2
MGC72201 2
SMDP3 2, 5
Descriptions
ABC transporter 3 2
ABC-C transporter 3
ATP-binding cassette 3 3
ATP-binding cassette transporter 3 3
ATP-binding cassette, sub-family A (ABC1), member 3 2
ATP-binding cassette, sub-family A member 3 2
ATP-binding cassette, sub-family A, member 3 1
External Ids
HGNC: 331
Entrez Gene: 212
UniProtKB: Q997583
Ensembl: ENSG000001679727
Search outside databases for aliases for ABCA3 gene

Previous GC identifers: GC16P002406 GC16M002351

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ABCA3:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding
cassette (ABC) transporters. ABC proteins transport various molecules across extra- and
intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP,
MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1
subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The
full transporter encoded by this gene may be involved in development of resistance to xenobiotics
and engulfment during programmed cell death. [provided by RefSeq]

UniProtKB/Swiss-Prot: ABCA3_HUMAN, Q99758
Function: Plays an important role in the formation of pulmonary surfactant, probably by
transporting lipids such as cholesterol

Gene Wiki entry for ABCA3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ABCA3 gene  

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

ABCA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M002265:     (about GC identifiers)

Start:
2,265,880 bp from pter
End:
2,330,748 bp from pter
Size:
64,869 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000016.8  NT_037887.4  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ABCA3_HUMAN, Q99758 (See protein sequence)
Recommended Name: ATP-binding cassette sub-family A member 3  
Size: 1704 amino acids; 191362 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q54A95 Q92473

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_001080.2  

    ENSEMBL proteins: 
    ENSP00000301732 ENSP00000371818 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (P180 Lamellar Body Protein)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    4 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005624 membrane fraction TAS9027511
    GO:0005886 plasma membrane IDA11718719
    GO:0016021 integral to membrane TAS9027511
    GO:0042599 lamellar body IDA11718719
    About this table

    Antibodies for ABCA3: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ABCA3
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (P180 Lamellar Body Protein), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for ABCA3

    Assays for ABCA3: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    3 InterPro domains/families:
     IPR003593 ATPase_AAA+_core
     IPR003439 ABC_transporter-like
     IPR017871 ABC_transporter_CS


       GeneDecks  ABCA3 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q99758

    ProtoNet protein and cluster: Q99758

    UniProtKB/Swiss-Prot: ABCA3_HUMAN, Q99758
    Domain: Multifunctional polypeptide with two homologous halves, each containing an hydrophobic
    membrane-anchoring domain and an ATP binding cassette (ABC) domain (By similarity)
    Similarity: Belongs to the ABC transporter family. ABCA subfamily
    Similarity: Contains 2 ABC transporter domains

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ABCA3)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ABCA3)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001089

                  Applied Biosystems Silencer® siRNAs for ABCA3

                  Sigma-Aldrich siRNA and siRNA Panels for ABCA3  
                         Sigma-Aldrich shRNA for ABCA3  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001089
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001089
                                     untagged cDNA clone in CMV expression vector: NM_001089 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001089

    UniProtKB/Swiss-Prot: ABCA3_HUMAN, Q99758
    Function: Plays an important role in the formation of pulmonary surfactant, probably by
    transporting lipids such as cholesterol

    Genatlas biochemistry entry for ABCA3:
    ATP binding cassette superfamily,subfamily A,member 3,involved in resistance to xenobiotics,mouse
    ABC2 (mu ABC2) homolog,highly expressed in lung,brain,heart,pancreas

    6 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Abca3):

    behavior/neurologicalhomeostasis/metabolismlethality-prenatal/perinatalrenal/urinary system
    respiratory system

    5 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0005215 transporter activity TAS9027511
    GO:0005524 ATP binding TAS9027511
    GO:0016887 ATPase activity IEA--
    GO:0042626 ATPase activity, coupled to transmembrane movement of substances TAS9027511
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Kegg Pathway  (Kegg details for ABCA3):
     hsa02010 ABC transporters

       GeneDecks  ABCA3 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  ABCA3 


    5/9 Interacting proteins for ABCA3 (ENSP000003718183) via UniProtKB, MINT, and/or STRING (see all 9 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NKX2-1ENSP000003539183STRING (score=.946)
    ABCA9ENSP000003422163STRING (score=.916)
    SFTPBENSP000003451613STRING (score=.849)
    STAT3ENSP000002646573STRING (score=.845)
    LEPREL2ENSP000002905103STRING (score=.842)
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810 transport IDA15531465
    GO:0042493 response to drug TAS8706931
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ABCA3
    2 Novoseek chemical compound relationships for ABCA3 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 28.06 1 15465012 (1)
    lipid 0.00 1 16847209 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ABCA3)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ABCA3)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001089

                  Sigma-Aldrich siRNA and siRNA Panels for ABCA3  
                         Sigma-Aldrich shRNA for ABCA3  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001089  

    REFSEQ mRNAs for ABCA3 gene: 

    NM_001089.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001089  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001089
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001089
                                     untagged cDNA clone in CMV expression vector: NM_001089 

    Additional cDNA sequence: 

    AB070929.1 AB210044.1 AK310864.1 BC020724.1 BC035752.1 BC062779.1 BC140895.1 BC146866.1 
    BC151840.1 U66675.1 U78735.1 X97187.1 

    9 DOTS entries:

    DT.415038  DT.97822342  DT.97797548  DT.95163281  DT.97846373  DT.120688009  DT.95163280  DT.91743399 
    DT.95163277 

    24/35 AceView cDNA sequences (see all 35 ):

    BE669619 X97187 AB070929 BE669421 BE251915 BC035752 NM_001089 BC020724 
    BC062779 U78735 AA351351 AW450470 BX372615 BQ328862 BX101771 BE671452 
    BM990801 BU856049 BF090334 BF091460 AW295642 BF923714 AW900257 T05334 

    highest scoring ESTs for ABCA3:

    U78735 AA351351 AB070929 AW296862 AW450470 BE251915 BF851463 BF923714 NM_001089 X97187 

    Unigene Cluster for ABCA3:

    ATP-binding cassette, sub-family A (ABC1), member 3
    Hs.26630  [show with all ESTs]
    Unigene Representative Sequence: NM_001089


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ABCA3

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
    SP1:                                            -                                                                                                               
    SP2:                                            -                       -                                                                                       
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            

    ExUns: 25a · 25b ^ 26 ^ 27a · 27b ^ 28 ^ 29 ^ 30 ^ 31 ^ 32
    SP1:  -                                                         
    SP2:  -                                                         
    SP3:                                                            
    SP4:                                                            

    About this scheme

    ECgene alternative splicing isoforms for ABCA3

    2 Ensembl transcripts including schematic representations:
    ENST00000301732  ENST00000382381  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ABCA3 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ABCA3

    1 / 2 / 3

    3 probe-sets matching ABCA3 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    35183_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 U78735 1.00 0.90 0.95 1

    204343_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001089 0.60 1.00 0.82 1

    204343_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ABCA3 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TGTCAAAAAA

    SOURCE GeneReport for Unigene cluster: Hs.26630

    Expression variation in blood from EXPOLDB for ABCA3

    UniProtKB/Swiss-Prot: ABCA3_HUMAN, Q99758
    Tissue specificity: Highly expressed in lung, followed by brain, pancreas, skeletal muscle and
    heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid
    carcinoma cells (MTC) and in C-cell carcinoma

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ABCA3 gene from 5/12 species (see all 12 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ABCA31   -- ATP-binding cassette, sub-family A (ABC1), member 3 86.54(n)
    88.07(a)
    479879  XM_537004.2  XP_537004.2 
    chimpanzee
    (Pan troglodytes)
    ABCA31   -- ATP-binding cassette, sub-family A (ABC1), member 3 99.24(n)
    99.59(a)
    453833  XM_510744.2  XP_510744.2 
    cow
    (Bos taurus)
    ABCA31   -- ATP-binding cassette, sub-family A (ABC1), member 3 87.55(n)
    89.14(a)
    505787  XM_582132.3  XP_582132.3 
    rat
    (Rattus norvegicus)
    Abca31   -- ATP-binding cassette, sub-family A (ABC1), member 3 84.69(n)
    88.19(a)
    302973  XM_220219.4  XP_220219.4 
    mouse
    (Mus musculus)
    Abca31, 5 175
    ATP-binding cassette, sub-family A (ABC1), member 31, 5 84.49(n)1
    88.09(a)1
    274101  NM_001039581.11  NP_001034670.11 
     AA1549975  AF2133945  (see all 24)
    About this table        Species with no ortholog for ABCA3

    ENSEMBL Gene Tree for ABCA3
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

      --
    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/402 NCBI SNPs in ABCA3 are shown (see all 402 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 106)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 16 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs3230481,2
    A,C,F2318664(-) GGACTC/GCTCTC 1 -- ut51 ese36Minor allele frequency- G:0.04EA NA MN NS 338
    rs41468251,2
    C,F,H2319812(-) GATGTC/TCTGCG 1 -- ut51 ese310Minor allele frequency- T:0.07EU EA WA NS 928
    rs171358801,2
    C,F,H2318457(+) AACCTG/CCTAGA 1 -- ut5113Minor allele frequency- C:0.02NA EU EA WA NS 996
    rs3230491,2
    C,F2318597(-) CCATCG/ACCTTC 1 -- ut516Minor allele frequency- A:0.05EA NA MN NS 338
    rs133327601,2
    H2279621(+) CCCGAC/ACCTGT 1 F/V mis14Minor allele frequency- A:0.00EU EA WA 390
    rs1495321,2
    A,C,F,H2271431(-) CCCAGC/TCCGGA 1 S/S syn1 ese311Minor allele frequency- T:0.11MN NA EU EA WA NS 872
    rs3230431,2
    C,F,H2288529(-) CCCCCC/GACCAG 1 P/P syn1 ese3 trp38Minor allele frequency- G:0.11MN EU EA WA NS 744
    rs133325141,2
    C,F2307337(+) ATGGCG/AAAGCA 1 F/F syn1 ese33Minor allele frequency- A:0.07NA NS 164
    --
    rs456205391,2
    F2285666(-) CACCAC/TGTGCC 1 H/H syn12Minor allele frequency- T:0.02NS 92
    --
    rs454805021,2
    F2309775(-) CATGCC/TGATGC 1 A/A syn12Minor allele frequency- T:0.02NS 94
    About this table

    HapMap Linkage Disequilibrium images for ABCA3 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 601615   disorders: 610921  

    UniProtKB/Swiss-Prot: ABCA3_HUMAN, Q99758

  • Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3
    (SMDP3) [MIM:610921]; also called pulmonary alveolar proteinosis due to ABCA3 deficiency. Inborn
    errors of pulmonary surfactant metabolism are genetically heterogeneous disorders resulting in
    severe respiratory insufficiency or failure in full-term neonates or infants. These disorders are
    associated with various pathologic entities, including pulmonary alveolar proteinosis (PAP),
    desquamative interstitial pneumonitis (DIP), or cellular non-specific interstitial pneumonitis
    (NSIP)
  • 1 Novoseek disease relationship for ABCA3 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    lung diseases 35.40 3 16982851 (1), 15985750 (1), 17127271 (1)
    About this table

    Human Gene Mutation Database: ABCA3
    Genetic Association Database: ABCA3
    Human Genome Epidemiology Navigator: ABCA3 (4 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/37 PubMed articles for ABCA3 gene (see all 37 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 21 HGNC: 33 AceView: ABCA3 Ensembl:ENSG00000167972 euGenes: HUgn21
    ECgene: ABCA3 H-InvDB: ABCA3
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    GeneReviewshttp://www.genetests.org/query?gene=ABCA3
    SeattleSNPshttp://pga.gs.washington.edu/data/abca3/
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ABCA3:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
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     Predesigned and custom siRNAs for ABCA3 Antibodies for ABCA3
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ABCA3 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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