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ABCA10 Gene

protein-coding   GIFtS: 50
GCID: GC17M067144

ATP-Binding Cassette, Sub-Family A (ABC1), Member 10

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATP-Binding Cassette, Sub-Family A (ABC1), Member 101 2
EST6987392
ATP-Binding Cassette A102
ATP-Binding Cassette Sub-Family A Member 102
EC 3.6.38
EC 3.6.3.418

External Ids:    HGNC: 301   Entrez Gene: 103492   Ensembl: ENSG000001542637   OMIM: 6125085   UniProtKB: Q8WWZ43   

Export aliases for ABCA10 gene to outside databases

Previous GC identifers: GC17M066943 GC17M070104 GC17M067601 GC17M067741 GC17M064650 GC17M062529


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ABCA10 Gene:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)
transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are
divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein
is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found
exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but
neither the substrate nor the function of this gene is known. (provided by RefSeq, Jul 2008)

GeneCards Summary for ABCA10 Gene:
ABCA10 (ATP-binding cassette, sub-family A (ABC1), member 10) is a protein-coding gene. GO annotations related to this gene include ATPase activity. An important paralog of this gene is ABCA1.

UniProtKB/Swiss-Prot: ABCAA_HUMAN, Q8WWZ4
Function: Probable transporter which may play a role in macrophage lipid homeostasis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the ABCA10 gene promoter:
         GR   Nkx3-1   Nkx3-1 v4   GR-beta   Nkx3-1 v1   C/EBPalpha   CHOP-10   Nkx3-1 v2   Nkx3-1 v3   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidABCA10 promoter sequence
   Search Chromatin IP Primers for ABCA10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ABCA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q24   Ensembl cytogenetic band:  17q24.3   HGNC cytogenetic band: 17q24

ABCA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ABCA10 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M067144:  view genomic region     (about GC identifiers)

Start:
67,143,355 bp from pter      End:
67,240,987 bp from pter
Size:
97,633 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ABCAA_HUMAN, Q8WWZ4 (See protein sequence)
Recommended Name: ATP-binding cassette sub-family A member 10  
Size: 1543 amino acids; 175790 Da
Secondary accessions: C9JZH2 C9K035 Q6PIQ6 Q7Z2I9 Q7Z7P7 Q86TD2
Alternative splicing: 5 isoforms:  Q8WWZ4-1   Q8WWZ4-2   Q8WWZ4-3   Q8WWZ4-4   Q8WWZ4-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ABCA10: NX_Q8WWZ4

Explore proteomics data for ABCA10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ABCA10 (Q8WWZ4) (see all 5)
     VLLLDEP  LDEPTAG  NGAGKST  DEPTAGLD 


    See ABCA10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_525021.3  
    ENSEMBL proteins: 
     ENSP00000468351   ENSP00000466506   ENSP00000269081   ENSP00000429853   ENSP00000430341  
     ENSP00000428032   ENSP00000429945   ENSP00000429795   ENSP00000407772   ENSP00000387674  
     ENSP00000394639  
    Reactome Protein details: Q8WWZ4

    ABCA10 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ABCA10

     
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    Search eBioscience for ELISAs for ABCA10 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ABCA: ATP binding cassette transporters / subfamily A

    IUPHAR Guide to PHARMACOLOGY protein family classification: ABCA10
    ABCA subfamily

    5 InterPro protein domains:
     IPR003439 ABC_transporter-like
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase
     IPR026082 ABC_A
     IPR017871 ABC_transporter_CS

    Graphical View of Domain Structure for InterPro Entry Q8WWZ4

    ProtoNet protein and cluster: Q8WWZ4

    UniProtKB/Swiss-Prot: ABCAA_HUMAN, Q8WWZ4
    Similarity: Belongs to the ABC transporter superfamily. ABCA family
    Similarity: Contains 2 ABC transporter domains


    Find genes that share domains with ABCA10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABCAA_HUMAN, Q8WWZ4
    Function: Probable transporter which may play a role in macrophage lipid homeostasis
    Induction: Down-regulated by cholesterol loading of macrophages

         Enzyme Numbers (IUBMB): EC 3.6.3.412 EC 3.6.32

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity IEA--
    GO:0017111nucleoside-triphosphatase activity ----
         
    Find genes that share ontologies with ABCA10           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ABCA10:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ABCA10
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ABCA10

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    GenScript: all cDNA clones in your preferred vector: ABCA10 (NM_080282)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABCA10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA10

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABCAA_HUMAN, Q8WWZ4: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ABCA10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ABCA10 About    
    See pathways by source

    SuperPathContained pathways About
    1ABC-family proteins mediated transport
    ABC-family proteins mediated transport0.69
    ABCA transporters in lipid homeostasis0.00
    ABC transporters0.69
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Transmembrane transport of small molecules0.47


    Find genes that share SuperPaths with ABCA10           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ABCA10
        ABCA transporters in lipid homeostasis


    1 Kegg Pathway  (Kegg details for ABCA10):
        ABC transporters

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ABCA10
    Interactions:

        GeneGlobe Interaction Network for ABCA10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ABCA10 (ENSP000002690814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABCG2ENSP000002376124STRING: ENSP00000237612
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--

    Find genes that share ontologies with ABCA10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ABCA10 (ABCAA)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ABCA10 gene: 
    NM_080282.3  

    Unigene Cluster for ABCA10:

    ATP-binding cassette, sub-family A (ABC1), member 10
    Hs.25377  [show with all ESTs]
    Unigene Representative Sequence: NM_080282
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000522787 ENST00000521538 ENST00000269081(uc010wqt.1 uc010dfa.1)
    ENST00000522406(uc010dfb.1) ENST00000524231(uc002jhz.3) ENST00000519732
    ENST00000518929 ENST00000523419 ENST00000588514 ENST00000523512 ENST00000524273
    ENST00000521526 ENST00000416101(uc010wqs.1) ENST00000432313(uc010dfc.1)
    ENST00000423818
    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ABCA10
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ABCA10 (NM_080282)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABCA10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABCA10
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      QuantiTect SYBR Green Assays in human, mouse, rat ABCA10
      QuantiFast Probe-based Assays in human, mouse, rat ABCA10

    Additional mRNA sequence: 

    AK298508.1 AK310858.1 AL832004.2 AY028900.1 AY247065.1 BC031026.1 BC051320.1 BC136460.1 
    BC144124.1 

    10 DOTS entries:

    DT.100777105  DT.100029318  DT.100777104  DT.100029319  DT.91981788  DT.92415839  DT.95358004  DT.425145 
    DT.100777106  DT.303146 

    Selected AceView cDNA sequences (see all 208):

    AI568925 CD629440 BE503590 BQ441353 AW189609 BQ000362 AV718464 AW440582 
    BG566938 CD629432 AL711380 AY028897 AI698175 BX280304 BF061307 BG288838 
    CA773849 NM_080282 AB067475 AJ512612 BU625990 AA988796 AL698749 NM_018672 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ABCA10 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21a · 21b · 21c · 21d
    SP1:                                                                                                        -           -                                 
    SP2:                                                                                                                                                      
    SP3:                                                                                                                    -                                 
    SP4:                                                                                                                                                      
    SP5:                                                                                                                    -                                 


    ECgene alternative splicing isoforms for ABCA10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ABCA10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ABCA10 Expression
    About this image

    ABCA10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ABCA10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.25377

    UniProtKB/Swiss-Prot: ABCAA_HUMAN, Q8WWZ4
    Tissue specificity: Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABCA10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ABCA10 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves --
    --
    Uncharacterized protein
    51(a)
    45(a)
    many ↔ many
    many ↔ many
    18(8206967-8226132)
    18(8181915-8205387)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    43(a)
    1 → many
    GL343630.1(35018-149208)
    zebrafish
    (Danio rerio)
    Actinopterygii abch16
    ATP-binding cassette, sub-family H, member 1
    17(a)
    many ↔ many
    17(24365342-24392834) ENSDARG00000071341
    fruit fly
    (Drosophila melanogaster)
    Insecta CG428166
    --
    22(a)
    many ↔ many
    3L(17785188-17790694)
    worm
    (Caenorhabditis elegans)
    Secernentea abt-56
    Protein ABT-5 (abt-5) mRNA, complete cds
    19(a)
    many ↔ many
    I(12011276-12018668) WBGene00000023
            Species with no ortholog for ABCA10

    ENSEMBL Gene Tree for ABCA10 (if available)
    TreeFam Gene Tree for ABCA10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ABCA10 gene
    ABCA12  ABCA132  ABCA32  ABCA82  ABCA122  ABCA42  ABCA72  ABCA22  
    ABCA92  ABCA62  ABCA52  
    13 SIMAP similar genes for ABCA10 using alignment to 6 protein entries:     ABCAA_HUMAN (see all proteins):
    ABCA11P    DKFZp686F2450    ABCA9    ABCA6    DKFZp686K07118    ABCA8
    ABCA5    ABC2    DKFZp547P193    ABCA2    ABCA13    ABCG2
    DKFZp434E1030

    Find genes that share paralogs with ABCA10           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ABCA10
    PGOHUM00000257145


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ABCA10 (see all 2081)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs749359441,2
    C--67143765(+) TGGCAG/TAGGTG 1 -- int14Minor allele frequency- T:0.06CSA WA NA EA 360
    rs1400200441,2
    --67143891(+) CATAAC/TTGCAA 1 -- int10--------
    rs49688411,2
    C,F,A,H--67143914(+) GCAATT/CCATGA 1 -- int112Minor allele frequency- C:0.37NS EA NA WA 780
    rs49688421,2
    C,F,A--67143971(+) CAACAT/CTGGGA 1 -- int110Minor allele frequency- C:0.44NA WA EA 372
    rs1499602401,2
    --67144034(+) GGATAC/GTGACT 1 -- int10--------
    rs49688431,2
    C,F,H--67144197(+) AACCCA/GAACGT 1 -- ut3131Minor allele frequency- G:0.33NS EA NA WA CSA 2915
    rs1827684191,2
    --67144200(+) CCGAAC/TGTAAC 1 -- ut310--------
    rs1874162311,2
    --67144371(+) ATACAC/TTGAAT 1 -- ut310--------
    rs22337671,2
    C,F,H--67144395(+) AGAAAA/GTATTA 1 -- ut3115Minor allele frequency- G:0.09NS EA CSA WA NA 2216
    rs1450430741,2
    C--67144450(+) ACTTCA/GATATG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ABCA10 (67143355 - 67240987 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ABCA10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2129CNV Insertion18451855
    nsv2128CNV Insertion18451855
    nsv457888CNV Loss19166990
    nsv516799CNV Loss19592680
    nsv470598CNV Loss18288195
    nsv833527CNV Gain+Loss17160897

    Human Gene Mutation Database (HGMD): ABCA10
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ABCA10
    DNA2.0 Custom Variant and Variant Library Synthesis for ABCA10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612508    OMIM disorders: --


    Find genes that share disorders with ABCA10           About GenesLikeMe


    Export disorders for ABCA10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ABCA10 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ABCA10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter. (PubMed id 12821155)1, 2, 3, 9 Wenzel J.J....Schmitz G. (Biochem. Biophys. Res. Commun. 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The human ATP-binding cassette (ABC) transporter superfamily. (PubMed id 11435397)1, 3 Dean M....Allikmets R. (Genome Res. 2001)
    4. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    6. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    7. Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PubMed id 16094384)1 Tao W.A....Aebersold R. (Nat. Methods 2005)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PubMed id 8894702)1 Allikmets R....Dean M. (Hum. Mol. Genet. 1996)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10349 HGNC: 30 AceView: ABCA5andABCA10 Ensembl:ENSG00000154263 euGenes: HUgn10349
    ECgene: ABCA10 Kegg: 10349 H-InvDB: ABCA10

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ABCA10 Pharmacogenomics, SNPs, Pathways
    ABCMdbhttp://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q8WWZ4

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ABCA10 gene:
    Search GeneIP for patents involving ABCA10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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