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AATF Gene

protein-coding GIFtS: 59

GC17P032380

apoptosis antagonizing transcription factor
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CHE-1 ^¹, ²
CHE1 ^¹, ², ³, ⁵
DED ^¹, ², ³

Descriptions
Apoptosis-antagonizing transcription factor ^³
Rb-binding protein Che-1 ^³
apoptosis antagonizing transcription factor ^²

External Ids
HGNC: 19235¹
Entrez Gene: 26574²
UniProtKB: Q9NY61³
Ensembl: ENSG00000108270⁷

Search outside databases for aliases for AATF gene

Previous GC identifers: GC17P034690 GC17P037258 GC17P035037 GC17P035501

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for AATF:

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a

protein kinase known to be involved in the induction of cell apoptosis. This gene product contains

a leucine zipper, which is a characteristic motif of transcription factors, and was shown to

exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of

this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq]

UniProtKB/Swiss-Prot: AATF_HUMAN, Q9NY61

Function: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the

pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F

target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the

CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle

progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in

Alzheimer disease (presenile and senile dementia), although the molecular basis for this

phenomenon has not been described to date

Gene Wiki entry for AATF (Apoptosis_antagonizing_transcription_factor)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the AATF gene

Entrez Gene cytogenetic band: 17q11.2-q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q12

AATF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P032380: (about GC identifiers)

Start:	32,380,288 bp from pter
End:	32,488,284 bp from pter
Size:	107,997 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000017.9 NT_078100.1

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: AATF_HUMAN, Q9NY61 (See protein sequence)

Recommended Name: Protein AATF

Size: 560 amino acids; 63133 Da

Subunit: Binds PAWR, POLR2J, RB1/RB, RBL1/P107, RBL2/P130, and SP1. May also bind MAPT

Subcellular location: Nucleus, nucleolus

Sequence caution: Sequence=AAD52016.1; Type=Frameshift; Positions=355, 365, 487, 498, 503;

Secondary accessions: A6NCJ6 B3KQ26 Q9P0A4 Q9UNX5

Post-translational modifications:

Hyperphosphorylated during the G1/S phase transition¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036270.1

ENSEMBL proteins:

ENSP00000225402

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (AATF)
	Human Recombinant Proteins from Abnova (AATF)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	12429849
GO:0005730	nucleolus	IDA	18029348
GO:0005813	centrosome	IDA	18029348
GO:0005925	focal adhesion	IDA	18029348
GO:0030054	cell junction	IDA	18029348

About this table

Antibodies for AATF:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for AATF
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (AATF), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (AATF)
	Novus Biologicals Antibodies for AATF

Assays for AATF:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9NY61

ProtoNet protein and cluster: Q9NY61

1 Blocks protein family: IPB012617 TRAUB

UniProtKB/Swiss-Prot: AATF_HUMAN, Q9NY61

Similarity: Belongs to the AATF family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (AATF)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (AATF)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012138

Applied Biosystems Silencer® siRNAs for AATF

Sigma-Aldrich siRNA for AATF

Sigma-Aldrich shRNA Panels and shRNA for AATF

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for AATF
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012138
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012138
untagged cDNA clones in CMV expression vector (see all 2): NM_012138

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012138

UniProtKB/Swiss-Prot: AATF_HUMAN, Q9NY61

Function: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the

pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F

target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the

CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle

progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in

Alzheimer disease (presenile and senile dementia), although the molecular basis for this

phenomenon has not been described to date

4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Aatf):

cellular

embryogenesis

growth/size

lethality-prenatal/perinatal

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	10580117
GO:0005515	protein binding	IPI	15231747 17157788

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for AATF

5/44 Interacting proteins for AATF (ENSP00000225402³ Q9NY61^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 44 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CHEK2	O96017¹	STRING (score=.959) EBI-372428, EBI-1180783
RELA	Q04206¹	STRING (score=.727) EBI-372428, EBI-73886
MAPT	P10636²	STRING (score=.968) MINT-49642 MINT-49641
POLR2J	P52435²	STRING (score=.788) MINT-49955 MINT-49956
ATM	Q13315¹	EBI-372428, EBI-495465

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006916	anti-apoptosis	TAS	10580117

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for AATF
1 Novoseek chemical compound relationship for AATF gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
leucine	39.44	3	15207272 (1), 14627703 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (AATF)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (AATF)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012138

Sigma-Aldrich siRNA for AATF

Sigma-Aldrich shRNA Panels and shRNA for AATF

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012138

REFSEQ mRNAs for AATF gene:

NM_012138.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012138

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012138
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012138
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_012138

Additional cDNA sequence:

AF083208.1 AF161395.1 AJ249940.2 AK026173.1 AK057229.1 AK130740.1 BC000591.2 CR616929.1

21 DOTS entries:

DT.92455094 DT.97860038 DT.99932217 DT.452954 DT.316399 DT.120894106 DT.100799882 DT.100799876

DT.91826648 DT.92455082 DT.95167005 DT.120893889 DT.87017028 DT.95166734 DT.120893894 DT.120894069

DT.91733647 DT.91994800 DT.95167000 DT.120894026 DT.120894145

24/362 AceView cDNA sequences (see all 362 ):

BU740585 AI817450 F34702 CB150276 BU169820 BG231720 BM855480 BG391551

CB151083 BE312780 BQ056766 BG191682 W77795 BU742473 AI003563 BM713071

AJ249940 AW964198 BQ225065 BC000591 AA290643 BM825155 AA291023 CB125443

highest scoring ESTs for AATF:

U51698 AA099988 AA211386 AA291023 AA317577 AA379087 AA379088 AA579979 AA625561 AA625749

Unigene Cluster for AATF:

Apoptosis antagonizing transcription factor

Hs.195740 [show with all ESTs]

Unigene Representative Sequence: NM_012138

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for AATF

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11a	·	11b	^	12a	·	12b	·	12c
SP1:																													-
SP2:							-		-		-
SP3:
SP4:																													-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for AATF

1 Ensembl transcript including schematic representation:

ENST00000225402

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

AATF expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for AATF

¹ / ² / ³

3 probe-sets matching AATF gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32117_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U51698	1.00	1.00	1.00	1
209165_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF083208	0.80	1.00	0.91	1
209165_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GCACCTATTG

SOURCE GeneReport for Unigene cluster: Hs.195740
Expression variation in blood from EXPOLDB for AATF
UniProtKB/Swiss-Prot: AATF_HUMAN, Q9NY61
Tissue specificity: Ubiquitously expressed. Expressed at high levels in brain, heart, kidney,
placenta and thymus

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for AATF gene from 5/21 species (see all 21 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	AATF¹	--	apoptosis antagonizing transcription factor	89.35(n) 89.77(a)	480595 XM_537715.2 XP_537715.2
chimpanzee (Pan troglodytes)	AATF¹	--	apoptosis antagonizing transcription factor	99.52(n) 99.64(a)	454601 XM_511427.2 XP_511427.2
cow (Bos taurus)	AATF¹	--	apoptosis antagonizing transcription factor	88.31(n) 89.42(a)	786013 XM_001252957.1 XP_001252958.1
rat (Rattus norvegicus)	Aatf¹	--	apoptosis antagonizing transcription factor	83.97(n) 84.87(a)	114512 NM_053720.1 NP_446172.1
mouse (Mus musculus)	Aatf^{1, 5}	11⁵	apoptosis antagonizing transcription factor^{1, 5}	83.75(n)¹ 84.13(a)¹	56321¹ NM_019816.1¹ NP_062790.1¹ AF222801⁵ AF322223⁵ (see all 18)

About this table Species with no ortholog for AATF

ENSEMBL Gene Tree for AATF

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/556 NCBI SNPs in AATF are shown (see all 556 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 153)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs11870749^1,2	A,C,F,H	32488438(+)	`acatgT/Cagatt`	1	--	ng3¹		8	EU EA WA	810
--	rs7216758^1,2	A,C,F,H	32379482(+)	`ACCGTG/TGGGGG`	1	--	ng5¹		6	NA EU EA	422
	rs1001814^1,2	A,C,F,H	32379903(-)	`GGATAC/TGCACG`	1	--	ng5¹		19	NA EA MN EU WA	2954
	rs2306658^1,2	C,F	32380425(-)	`GACTCA/C/GGCCAG`	1	--	ut5¹		4	EA MN	2938
	rs11653434^1,2	C,F	32488119(+)	`TGGTGC/TGGCTG`	1	--	ut3¹ ese³		2	NA	182
	rs11650575^1,2	H	32384701(+)	`GAAGAA/CCCAGA`	1	N/T	mis¹		4	EU EA WA	418
--	rs28384473^1,2	F	32380170(+)	`CACTGG/-CCGCG`	1	--	ng5¹		2	MN EA	1252
	rs1045056^1,2	C,F,H,O	32420754(+)	`CGCTCT/CGTCTA`	1	S/S	syn¹		8	MN NA EU EA WA	744
	rs17139107^1,2	C,F,H	32450464(+)	`CCCAAC/TGATCA`	1	N/N	syn¹ ese³		7	NA EU EA WA	562
	rs873950^1,2	A,C,F,H,O	32452041(-)	`GAGCTA/GCTTGG`	1	--	int¹		16	EA NA EU WA	2564

About this table

HapMap Linkage Disequilibrium images for AATF (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 608463

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/28 PubMed articles for AATF gene (see all 28 ):

Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb. (PubMed id 10783144)^{1, 2, 3, 4} Fanciulli M....Passananti C. (2000)
Identification of novel transcription factor-like gene from human intestinal cells. (PubMed id 11027528)^{2, 3, 4} Lindfors K.... Kainulainen H. (2000)
AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4. (PubMed id 14627703)^{1, 3, 4} Guo Q. and Xie J. (2004)
AATF protects neural cells against oxidative damage induced by amyloid beta-peptide. (PubMed id 15207272)^{1, 3, 4} Xie J. and Guo Q. (2004)
Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis. (PubMed id 14697667)^{1, 3, 4} Barbato C....Passananti C. (2003)
Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220)^{3, 4} Nousiainen M.... Koerner R. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter. (PubMed id 12847090)^{3, 4} Di Padova M....Fanciulli M. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 26574	HGNC: 19235	AceView: AATF	Ensembl:ENSG00000108270	euGenes: HUgn26574
ECgene: AATF	H-InvDB: AATF

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for AATF	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for AATF
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for AATF:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for AATF-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for AATF		Antibodies for AATF
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for AATF		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (AATF)
	Antibodies (AATF)
	Chimera RNAi (AATF)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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Search Tocris compounds for AATF

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for AATF

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AATF Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for AATF

Summaries
for AATF

Genomic Location
for AATF

Proteins
for AATF

Protein Domains/
Families
for AATF

Gene Function
for AATF

Pathways & Interactions
for AATF

Drugs & Compounds
for AATF

Transcripts
for AATF

Expression
for AATF

Orthologs
for AATF

Paralogs
for AATF

SNPs/Variants
for AATF

Disorders & Mutations
for AATF

Medical News
for AATF

Publications
for AATF

Search for AATF

Genome Databases showing AATF

Other Databases showing AATF

Specialized Databases showing AATF

Licensable Technologies
for AATF

Services
for AATF

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

AATF Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor AATF

Summariesfor AATF

Genomic Locationfor AATF

Proteinsfor AATF

Protein Domains/Familiesfor AATF

Gene Functionfor AATF

Pathways & Interactionsfor AATF

Drugs & Compoundsfor AATF

Transcriptsfor AATF

Expression for AATF

Orthologsfor AATF

Paralogsfor AATF

SNPs/Variantsfor AATF

Disorders & Mutationsfor AATF

Medical Newsfor AATF

Publicationsfor AATF

Search for AATF

Genome Databases showing AATF

Other Databases showing AATF

Specialized Databases showing AATF

Licensable Technologiesfor AATF

Servicesfor AATF

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for AATF

Summaries
for AATF

Genomic Location
for AATF

Proteins
for AATF

Protein Domains/
Families
for AATF

Gene Function
for AATF

Pathways & Interactions
for AATF

Drugs & Compounds
for AATF

Transcripts
for AATF

Expression
for AATF

Orthologs
for AATF

Paralogs
for AATF

SNPs/Variants
for AATF

Disorders & Mutations
for AATF

Medical News
for AATF

Publications
for AATF

Licensable Technologies
for AATF

Services
for AATF