Aliases for AASDHPPT Gene
- Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase 2 3
- Alpha-Aminoadipic Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase 3 4
- 4-Phosphopantetheinyl Transferase 3 4
- LYS5 Ortholog 3 4
- AASD-PPT 3 4
- L-Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase 3
External Ids for AASDHPPT Gene
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for AASDHPPT Gene
AASDHPPT (Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase) is a Protein Coding gene. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include magnesium ion binding and holo-[acyl-carrier-protein] synthase activity.
UniProtKB/Swiss-Prot for AASDHPPT Gene
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.