Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AARSD1 Gene

protein-coding   GIFtS: 41
GCID: GC17M041102

Alanyl-TRNA Synthetase Domain Containing 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Alanyl-TRNA Synthetase Domain Containing 11 2
Alanyl-TRNA Synthetase Domain-Containing Protein 12 3
Alanyl-TRNA Editing Protein Aarsd12

External Ids:    HGNC: 284171   Entrez Gene: 807552   Ensembl: ENSG000002669677   OMIM: 6132125   UniProtKB: Q9BTE63   

Export aliases for AARSD1 gene to outside databases

Previous GC identifers: GC17M038357 GC17M036868


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AARSD1 Gene: 
AARSD1 (alanyl-tRNA synthetase domain containing 1) is a protein-coding gene. Diseases associated with AARSD1 include ovarian cancer. GO annotations related to this gene include alanine-tRNA ligase activity and molecular_function. An important paralog of this gene is PTGES3.

UniProtKB/Swiss-Prot: AASD1_HUMAN, Q9BTE6
Function: Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AARSD1 gene promoter:
         RREB-1   AP-2beta   Meis-1a   AP-2alpha   AP-2gamma   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAARSD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AARSD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AARSD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.31   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21.31

AARSD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AARSD1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M041102:  view genomic region     (about GC identifiers)

Start:
41,102,543 bp from pter      End:
41,132,545 bp from pter
Size:
30,003 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AASD1_HUMAN, Q9BTE6 (See protein sequence)
Recommended Name: Alanyl-tRNA editing protein Aarsd1  
Size: 412 amino acids; 45480 Da
Cofactor: Binds 1 zinc ion per subunit (Potential)
Subcellular location: Cytoplasm (By similarity)
Secondary accessions: B4DI73
Alternative splicing: 3 isoforms:  Q9BTE6-1   Q9BTE6-2   Q9BTE6-3   (Based on a readthrough transcript which may produce a PTGES3L-AARSD1 fusion protein. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AARSD1: NX_Q9BTE6

Explore proteomics data for AARSD1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BTE6

  • AARSD1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AARSD1 Protein Expression
    REFSEQ proteins: NP_001248363.1  
    ENSEMBL proteins: 
     ENSP00000467714   ENSP00000400870   ENSP00000387415   ENSP00000400735   ENSP00000467696  
     ENSP00000404894  

    Human Recombinant Protein Products for AARSD1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for AARSD1
    GenScript Custom Purified and Recombinant Proteins Services for AARSD1
    Novus Biologicals AARSD1 Protein
    Novus Biologicals AARSD1 Lysates
    Sino Biological Recombinant Protein for AARSD1
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AARSD1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--

    AARSD1 for ontologies           About GeneDecksing



    AARSD1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for AARSD1
    GenScript Custom Superior Antibodies Services for AARSD1
    Novus Biologicals AARSD1 Antibodies
    Abcam antibodies for AARSD1
    Cloud-Clone Corp. Antibodies for AARSD1 
    ThermoFisher Antibodies for AARSD1
    LSBio Antibodies in human, mouse, rat for AARSD1 

    Assay Products for AARSD1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for AARSD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for AARSD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for AARSD1 
    Cloud-Clone Corp. CLIAs for AARSD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR018163 Thr/Ala-tRNA-synth_IIc_edit
     IPR018165 Ala-tRNA-synth_IIc_core
     IPR018164 Ala-tRNA-synth_IIc_N
     IPR012947 tRNA_SAD

    Graphical View of Domain Structure for InterPro Entry Q9BTE6

    ProtoNet protein and cluster: Q9BTE6

    UniProtKB/Swiss-Prot: AASD1_HUMAN, Q9BTE6
    Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily


    AARSD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AASD1_HUMAN, Q9BTE6
    Function: Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala) (By similarity)

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003674molecular_function ND--
    GO:0003676nucleic acid binding IEA--
    GO:0004813alanine-tRNA ligase activity IEA--
    GO:0005524ATP binding IEA--
         
    AARSD1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for AARSD1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AARSD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AARSD1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for AARSD1 

    miRNA
    Products:
        
    miRTarBase miRNAs that target AARSD1:
    hsa-let-7b (MIRT001655)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AARSD1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate AARSD1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AARSD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AARSD1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for AARSD1
    Sirion Biotech Customized adenovirus for overexpression of AARSD1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    Browse OriGene untagged/tagged cDNA clones in CMV expression vector
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): AARSD1 (NM_025267)
    Sino Biological Human cDNA Clone for AARSD1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AARSD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AARSD1
    Sirion Biotech Customized lentivirus for stable overexpression of AARSD1 
                         Customized lentivirus expression plasmids for stable overexpression of AARSD1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for AARSD1
    Search LifeMap BioReagents cell lines for AARSD1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AARSD1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AARSD1

    5/15 Interacting proteins for AARSD1 (Q9BTE63) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARPC1AQ927473I2D: score=3 
    ACTR2P611603I2D: score=1 
    ACTR3BQ9P1U13I2D: score=1 
    ARPC2O151443I2D: score=1 
    ARPC3O151453I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006419alanyl-tRNA aminoacylation IEA--
    GO:0008150biological_process ND--
    GO:0043039tRNA aminoacylation ----

    AARSD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AARSD1 (AASD1)

    Search CenterWatch for drugs/clinical trials and news about AARSD1 / AASD1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AARSD1 gene: 
    NM_001261434.1  

    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000587023 ENST00000593123 ENST00000592136 ENST00000486493 ENST00000591096
    ENST00000474578 ENST00000427569 ENST00000483535 ENST00000486664 ENST00000478040
    ENST00000491665 ENST00000450475 ENST00000441280(uc010cyu.1) ENST00000430739
    ENST00000591910 ENST00000483774 ENST00000436545 ENST00000416949
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AARSD1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate AARSD1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AARSD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AARSD1
    Clone
    Products:
         
    Browse OriGene untagged/tagged cDNA clones in CMV expression vector
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): AARSD1 (NM_025267)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AARSD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AARSD1
    Sirion Biotech Customized lentivirus for stable overexpression of AARSD1 
                         Customized lentivirus expression plasmids for stable overexpression of AARSD1 
    Primer
    Products:
        
    Browse OriGene qPCR
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AARSD1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AARSD1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AARSD1

    24/223 AceView cDNA sequences (see all 223):

    AI354976 BQ021729 BM714928 AA315994 BF588584 W81432 BG104425 BE465035 
    AI680102 CA426522 BQ278878 CR619011 BX406721 BC019324 CR621048 CB240971 
    BM827274 AI140327 BE504977 AK056965 AW471359 BU633849 AI810550 CA950887 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AARSD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAACTGAAAA
    AARSD1 Expression
    About this image


    See AARSD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AARSD1
        SABiosciences Custom PCR Arrays for AARSD1
    Primer
    Products:
    Browse OriGene qPCR
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AARSD1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AARSD1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AARSD1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AARSD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for AARSD1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves AARSD11 alanyl-tRNA synthetase domain containing 1 71.38(n)
    74.86(a)
      420013  XM_001235321.2  XP_001235322.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    53(a)
    possible ortholog
    6(62455217-62479605)
    African clawed frog
    (Xenopus laevis)
    Amphibia mgc2744-prov2 hypothetical protein MGC52898 76.96(n)    BC043754.1 
    zebrafish
    (Danio rerio)
    Actinopterygii aarsd16
    si:ch211-131k2.36
    si:ch211-131k2.3
    59(a)
    3(a)
    1 ↔ 1
    possible ortholog
    12(6732851-6746824)
    12(6686211-6690361)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG108026
    --
    36(a)
    1 → many
    X(3376998-3378588)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YNL040W6
    Putative protein of unknown function with strong s...
    18(a)
    1 → many
    XIV(553380-554750)
            Species with no ortholog for AARSD1

    ENSEMBL Gene Tree for AARSD1 (if available)
    TreeFam Gene Tree for AARSD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AARSD1 gene
    PTGES32  PTGES3L-AARSD12  PTGES3L2  
    18/34 SIMAP similar genes for AARSD1 using alignment to 6 protein entries:     AASD1_HUMAN (see all proteins) (see all similar genes):
    KIAA1651    PTGES3L-AARSD1    ARIH1    EIF3G    KIAA0101    LSM12
    ZNF257    ZNF799    CALCOCO2    PFKFB3    TMX3    TUBA1C
    ZNF114    RAD51    FRG1    PARK2    SEC14L3    TMSB15B

    AARSD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for AARSD1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2672913CNV Deletion23128226
    esv1503826CNV Deletion17803354
    esv1214844CNV Insertion17803354
    nsv2057CNV Insertion18451855
    nsv457742CNV Loss19166990
    nsv908258CNV Loss21882294
    nsv112322CNV Loss16902084
    nsv483009CNV Gain15286789
    esv33998OTHER Inversion15654335

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing AARSD1
    DNA2.0 Custom Variant and Variant Library Synthesis for AARSD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613212    OMIM disorders: --

    2 diseases for AARSD1:    About MalaCards
    ovarian cancer    


    AARSD1 for disorders           About GeneDecksing


    Export disorders for AARSD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AARSD1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with AARSD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    4. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
    10. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80755 HGNC: 28417 AceView: MGC2744 Ensembl:ENSG00000266967 euGenes: HUgn80755
    ECgene: AARSD1 H-InvDB: AARSD1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AARSD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AARSD1 gene:
    Search GeneIP for patents involving AARSD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for AARSD1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   Browse OriGene clones  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for AARSD1   OriGene Custom Protein Services for AARSD1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AARSD1
     QIAGEN SeqTarget long-range PCR primers for resequencing AARSD1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AARSD1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AARSD1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AARSD1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AARSD1
     GenScript Custom Purified and Recombinant Proteins Services for AARSD1 GenScript cDNA clones with any tag delivered in your preferred vector for AARSD1
     GenScript Custom Assay Services for AARSD1 GenScript Custom Superior Antibodies Services for AARSD1
     GenScript Custom overexpressing Cell Line Services for AARSD1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in AARSD1 promoter
     Search Chromatin IP Primers for AARSD1
     RT2 qPCR Primer Assay in human, mouse, rat AARSD1
     Search GNC Networks for AARSD1
     SABiosciences Custom PCR Arrays for AARSD1
     Search Tocris compounds for AARSD1 (AASD1)
     Proteins and Antibodies for AARSD1
     Browse Sino Biological Cell Lysates
     cDNA Clones for AARSD1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     AARSD1 antibodies
     AARSD1 proteins
     AARSD1 lysates
     Antibodies for AARSD1
     See all of Abcam's Antibodies, Kits and Proteins for AARSD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for AARSD1
     Antibodies for AARSD1
     ELISAs for AARSD1
     CLIAs for AARSD1
     Search LifeMap BioReagents cell lines for AARSD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AARSD1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for AARSD1
     SwitchGear Promoter luciferase reporter plasmids for AARSD1
     ThermoFisher Antibodies for AARSD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AARSD1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for AARSD1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AARSD1
    Customized:
     lentivirus for stable overexpression of AARSD1
     lentivirus expression plasmids for stable overexpression of AARSD1
     adenovirus for overexpression of AARSD1
     LSBio Antibodies in human, mouse, rat for AARSD1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      AARSD1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4