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Aliases & Descriptions for AARSD1
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Descriptions alanyl-tRNA synthetase domain containing 1 2
Search outside databases for aliases for AARSD1 gene
Summaries for AARSD1 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Location for AARSD1
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the AARSD1 gene Entrez Gene cytogenetic band: 17q21.31 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31 AARSD1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17M038357:
(about GC identifiers )
Start:
38,356,069 bp from pter
End:
38,386,033 bp from pter
Size:
29,965 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000017.9 NT_010755.15 Proteins for AARSD1
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: AASD1_HUMAN, Q9BTE6 (See
protein sequence )Recommended Name: Alanyl-tRNA synthetase domain-containing protein 1 Size : 412 amino acids; 45480 DaAlternative splicing : 2 isoforms : Q9BTE6-1 Q9BTE6-2
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (4 alternative transcripts):
NP_001129514.2 NP_001136125.1 NP_001136126.1 NP_079543.1 ENSEMBL proteins: ENSP00000386254 ENSP00000386902 ENSP00000353355 ENSP00000386621 Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: AARSD1 1 Gene Ontology (GO) cellular component term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005737 cytoplasm
IEA --
About this table Antibodies for AARSD1: Assays for AARSD1:
Protein
Domains/ Families for AARSD1(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9BTE6 ProtoNet protein and cluster: Q9BTE6
UniProtKB/Swiss-Prot: AASD1_HUMAN, Q9BTE6 Similarity : Belongs to the class-II aminoacyl-tRNA synthetase family. AARSD1 subfamily
Gene Function for AARSD1
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4 ): NM_025267 Applied Biosystems Silencer ® siRNAs for AARSD1 Sigma-Aldrich siRNA for AARSD1 Sigma-Aldrich shRNA for AARSD1 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_001136042                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_001136042                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_001136042  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001136042 5 Gene Ontology (GO) molecular function terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0000166 nucleotide binding
IEA -- GO:0003676 nucleic acid binding
IEA -- GO:0004813 alanine-tRNA ligase activity
IEA -- GO:0005524 ATP binding
IEA -- GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
IEA --
About this table
Pathways & Interactions for AARSD1
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for AARSD1 (Your Favorite Gene powered by Ingenuity) 2 Interacting proteins for AARSD1 (ENSP00000353355 3 ) via UniProtKB, MINT, and/or STRING About this table 3 Gene Ontology (GO) biological process terms (links to tree view) :
About this table
Drugs & Compounds for AARSD1 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for AARSD1
Transcripts for AARSD1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
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OriGene ,
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4 ): NM_025267 Sigma-Aldrich siRNA for AARSD1 Sigma-Aldrich shRNA for AARSD1 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001136042 NM_001142653 NM_001142654 NM_025267
REFSEQ mRNAs for AARSD1 gene (4 alternative transcripts): NM_001136042.2 NM_001142653.1 NM_001142654.1 NM_025267.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001136042 NM_001142653 NM_001142654 NM_025267
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_001136042                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_001136042                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_001136042  
Additional cDNA sequence: AK056965.1 AK094084.1 AK295447.1 BC004172.2 BC019324.1 CR608238.1 CR613084.1 CR617160.1 CR619011.1 CR621048.1
24/25 DOTS entries (see all 25
): DT.455480 DT.100782335 DT.100782338 DT.120991248 DT.95271937 DT.92433390 DT.311916 DT.99927608 DT.306808 DT.100782337 DT.86852121 DT.92433393 DT.91940316 DT.95271935 DT.95324043 DT.100638559 DT.120991209 DT.120991216 DT.120991219 DT.120991254 DT.40131627 DT.91843276 DT.92433386 DT.95271951
24/223 AceView cDNA sequences (see all 223
):AI671153 BF588584 AI680102 CR619011 BM714928 BM767505 AA315994 CR608238 BE465035 AI275613 AI698559 AL539434 AW296090 BC019324 BM803564 BQ278878 CD368831 BM827274 BX406721 AI140327 AI669256 CR617160 W81432 BC004172
highest scoring ESTs for AARSD1 :AF039235 AA180872 AK056965 AK094084 AW245514 BC004172 BC019324 AA040597 AA249437 AA359868
Unigene Cluster for AARSD1: Alanyl-tRNA synthetase domain containing 1 Hs.317403 [show with all ESTs ] Unigene Representative Sequence: NM_001136042 GeneLoc Exon Structure 5/11 Alternative Splicing Database (ASD) splice patterns (SP) for AARSD1 (see all 11
) ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b · 14c ^ SP1 :     -       -           -       -   -   -                       SP2 :                     -                                 SP3 :               -       -                                 SP4 :                     -                                 SP5 :                                                    
ExUns: 15a · 15b ^ 16 ^ 17 SP1 :         SP2 :         SP3 :         SP4 :         SP5 :        
About this scheme ECgene alternative splicing isoforms for AARSD1 4 Ensembl transcripts including schematic representations : ENST00000409103
ENST00000409446
ENST00000360221
ENST00000409399
Expression for AARSD1
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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AARSD1 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for AARSD1 1 / 2 / 3
6 probe-sets matching AARSD1 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GAACTGAAAASOURCE GeneReport for Unigene cluster: Hs.317403
Orthologs for AARSD1
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for AARSD1 gene from 5/13 species (see all 13
)
About this table Species with no ortholog for AARSD1 ENSEMBL Gene Tree for AARSD1 Paralogs for AARSD1 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for AARSD1 gene PTGES3 2
SNPs/Variants for AARSD1 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for AARSD1 (up to first 250kb)
Disorders & Mutations for AARSD1
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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Medical News for AARSD1 (Possibly Related Articles in
Doctor's Guide )
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Publications for AARSD1 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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7 PubMed articles for AARSD1 gene :
Search for AARSD1
(in PubMed ,
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Genome Databases showing AARSD1
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing AARSD1
(According to HUGE )
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Specialized Databases showing AARSD1 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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