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Aliases & Descriptions for AARS2
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| AARSL 2, 3 | | AlaRS 3 | | EC 6.1.1.7 3 | | KIAA1270 1, 2, 3, 5 | | MT-ALARS 2 | | MTALARS 2, 5 | | OTTHUMP00000016528 2 | | OTTHUMP00000039883 2 | | bA444E17.1 1, 2 |
| | | Descriptions |
|---|
| Alanine--tRNA ligase 3 | | Alanyl-tRNA synthetase-like 3 | | alanine tRNA ligase 2, mitochondrial (putative) 2 | | alanyl-tRNA synthetase 2, mitochondrial 2 | | alanyl-tRNA synthetase 2, mitochondrial (putative) 2 | | alanyl-tRNA synthetase like 1, 2 |
|
| | Search outside databases for aliases for AARS2 gene |
Summaries for AARS2(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location for AARS2
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1AARS2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M044376:
(about GC identifiers)
Start:
|
44,374,441 bp from pter |
End:
|
44,389,041 bp from pter |
Size:
|
14,601 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000006.10 NT_007592.14
| Proteins for AARS2
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: SYAM_HUMAN, Q5JTZ9 (See
protein sequence)Recommended Name: Probable alanyl-tRNA synthetase, mitochondrial precursor Size: 985 amino acids; 107340 Da
Subcellular location: Mitochondrion matrix (By similarity)
Secondary accessions: A2RRN5 Q8N198 Q96D02 Q9ULF0REFSEQ proteins: NP_065796.1
ENSEMBL proteins: ENSP00000244571
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
3 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for AARS2: Assays for AARS2: | Protein
Domains/ Families for AARS2(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q5JTZ9
ProtoNet protein and cluster: Q5JTZ9 1 Blocks protein family: IPB002318 Alanyl-tRNA synthetase signature
UniProtKB/Swiss-Prot: SYAM_HUMAN, Q5JTZ9Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family | Gene Function for AARS2
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_020745
Applied Biosystems Silencer® siRNAs for AARS2
Sigma-Aldrich siRNA for AARS2  Sigma-Aldrich shRNA for AARS2  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_020745                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_020745                                  untagged cDNA clone in CMV expression vector: NM_020745 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_020745
UniProtKB/Swiss-Prot: SYAM_HUMAN, Q5JTZ9Catalytic activity: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)Enzyme Number (IUBMB): EC 6.1.1.7 5 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for AARS2
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| 2 Sigma-Aldrich "Your Favorite Gene" Pathways for AARS2 (Your Favorite Gene powered by Ingenuity) 
5/9 Interacting proteins for AARS2 (ENSP000002445713) via UniProtKB, MINT, and/or STRING (see all 9
)About this table
3 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for AARS2(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for AARS2
|
Transcripts for AARS2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_020745
Sigma-Aldrich siRNA for AARS2  Sigma-Aldrich shRNA for AARS2  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_020745 REFSEQ mRNAs for AARS2 gene: NM_020745.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_020745               OriGene GFP tagged cDNA clone in CMV expression vector: NM_020745                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_020745                                  untagged cDNA clone in CMV expression vector: NM_020745  Additional cDNA sequence: AB033096.1 BC013593.1 BC021131.1 BC033169.1 BC041026.1 BC128175.1 BC131728.1 CR612653.1 7 DOTS entries: DT.110699 DT.208413 DT.95376032 DT.100025489 DT.121344622 DT.91953897 DT.99927375 24/121 AceView cDNA sequences (see all 121
):BI789129 BQ682453 CK821197 AI806436 BQ883770 BM042314 BU146586 CR612653 AI381515 BI769677 C01141 BQ642175 BI770414 AI183453 BQ925080 BM545479 AB033096 BI859749 BE794883 BE464558 BU174518 AA627815 CA312977 AI942297 Unigene Cluster for AARS2: Alanyl-tRNA synthetase 2, mitochondrial (putative) Hs.158381 [show with all ESTs]Unigene Representative Sequence: NM_020745
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000244571
|
Expression for AARS2
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| AARS2 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for AARS2
1 / 2 7 probe-sets matching AARS2 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.158381
|
Orthologs for AARS2
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for AARS2 gene from 5/7 species (see all 7
)
About this table Species with no ortholog for AARS2
ENSEMBL Gene Tree for AARS2 | Paralogs for AARS2(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for AARS2 gene
- AARS2
|
SNPs/Variants for AARS2(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for AARS2 (up to first 250kb)
|
Disorders & Mutations for AARS2
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 612035
|
Medical News for AARS2(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for AARS2 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 8 PubMed articles for AARS2 gene: |
Search for AARS2
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing AARS2
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing AARS2
(According to HUGE)
About This Section
| |
Specialized Databases showing AARS2(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for AARS2(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for AARS2:

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Incremental update: 13 Oct 2009
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