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Aliases for AARD Gene

Aliases for AARD Gene

  • Alanine And Arginine Rich Domain Containing Protein 2 3
  • Alanine And Arginine-Rich Domain-Containing Protein 2 3
  • C8orf85 3 4
  • Chromosome 8 Open Reading Frame 85 2

External Ids for AARD Gene

Previous HGNC Symbols for AARD Gene

  • C8orf85

Previous GeneCards Identifiers for AARD Gene

  • GC08P117951

Summaries for AARD Gene

GeneCards Summary for AARD Gene

AARD (Alanine And Arginine Rich Domain Containing Protein) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AARD Gene

Genomics for AARD Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for AARD Gene

Start:
116,938,199 bp from pter
End:
116,944,487 bp from pter
Size:
6,289 bases
Orientation:
Plus strand

Genomic View for AARD Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AARD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AARD Gene

No data available for Regulatory Elements for AARD Gene

Proteins for AARD Gene

  • Protein details for AARD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4LEZ3-AARD_HUMAN
    Recommended name:
    Alanine and arginine-rich domain-containing protein
    Protein Accession:
    Q4LEZ3
    Secondary Accessions:
    • A5PKU8

    Protein attributes for AARD Gene

    Size:
    155 amino acids
    Molecular mass:
    17575 Da
    Quaternary structure:
    No Data Available

neXtProt entry for AARD Gene

Proteomics data for AARD Gene at MOPED

Post-translational modifications for AARD Gene

No Post-translational modifications

Other Protein References for AARD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for AARD Gene

Domains for AARD Gene

Protein Domains for AARD Gene

ProtoNet:

Suggested Antigen Peptide Sequences for AARD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AARD: view

No data available for Gene Families and UniProtKB/Swiss-Prot for AARD Gene

Function for AARD Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for AARD

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AARD Gene

Localization for AARD Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AARD Gene

Pathways for AARD Gene

SuperPathways for AARD Gene

No Data Available

Interacting Proteins for AARD Gene

Gene Ontology (GO) - Biological Process for AARD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030324 lung development IEA --
genes like me logo Genes that share ontologies with AARD: view

No data available for Pathways by source for AARD Gene

Transcripts for AARD Gene

mRNA/cDNA for AARD Gene

(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AARD Gene

Alanine and arginine rich domain containing protein:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for AARD

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for AARD
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for AARD Gene

No ASD Table

Relevant External Links for AARD Gene

GeneLoc Exon Structure for
AARD
ECgene alternative splicing isoforms for
AARD

Expression for AARD Gene

mRNA expression in normal human tissues for AARD Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for AARD Gene

This gene is overexpressed in Esophagus - Muscularis (9.6), Testis (9.1), Esophagus - Gastroesophageal Junction (7.2), Colon - Sigmoid (4.5), and Bladder (4.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for AARD Gene

SOURCE GeneReport for Unigene cluster for AARD Gene Hs.437551

genes like me logo Genes that share expressions with AARD: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for AARD Gene

Orthologs for AARD Gene

This gene was present in the common ancestor of mammals.

Orthologs for AARD Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AARD 35
  • 98.7 (n)
  • 96.75 (a)
AARD 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia AARD 35
  • 75 (n)
  • 56.58 (a)
AARD 36
  • 54 (a)
OneToOne
dog
(Canis familiaris)
Mammalia AARD 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Aard 35
  • 71.02 (n)
  • 58.82 (a)
Aard 16
Aard 36
  • 52 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Aard 35
  • 70.97 (n)
  • 56.77 (a)
Species with no ortholog for AARD:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AARD Gene

ENSEMBL:
Gene Tree for AARD (if available)
TreeFam:
Gene Tree for AARD (if available)

Paralogs for AARD Gene

Selected SIMAP similar genes for AARD Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with AARD: view

No data available for Paralogs for AARD Gene

Variants for AARD Gene

Sequence variations from dbSNP and Humsavar for AARD Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs958637 -- 116,936,747(-) gagga(A/G)actaa upstream-variant-2KB
rs1348794 -- 116,936,602(-) AGAGA(A/G)TTGCT upstream-variant-2KB
rs2166482 -- 116,940,942(-) TGTAT(A/T)ATTCA intron-variant
rs2921723 -- 116,937,345(-) AGTGT(A/G)TGGCA upstream-variant-2KB
rs3020179 -- 116,937,463(+) CAGGC(C/T)TCATC upstream-variant-2KB

Relevant External Links for AARD Gene

HapMap Linkage Disequilibrium report
AARD

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for AARD Gene

Disorders for AARD Gene

No disorders were found for AARD Gene.

No data available for UniProtKB/Swiss-Prot for AARD Gene

Publications for AARD Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Genome-wide searching of rare genetic variants in WTCCC data. (PMID: 20549515) Feng T. … Zhu X. (Hum. Genet. 2010) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for AARD Gene

Sources for AARD Gene

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