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Aliases for AAMDC Gene

Aliases for AAMDC Gene

  • Adipogenesis Associated, Mth938 Domain Containing 2 3 5
  • Adipogenesis Associated Mth938 Domain-Containing Protein 3 4
  • C11orf67 3 4
  • Chromosome 11 Open Reading Frame 67 2
  • UPF0366 Protein C11orf67 3
  • PTD015 3
  • CK067 3

External Ids for AAMDC Gene

Previous HGNC Symbols for AAMDC Gene

  • C11orf67

Previous GeneCards Identifiers for AAMDC Gene

  • GC11P077533

Summaries for AAMDC Gene

GeneCards Summary for AAMDC Gene

AAMDC (Adipogenesis Associated, Mth938 Domain Containing) is a Protein Coding gene.

UniProtKB/Swiss-Prot for AAMDC Gene

  • May play a role in preadipocyte differentiation and adipogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AAMDC Gene

Genomics for AAMDC Gene

Regulatory Elements for AAMDC Gene

Enhancers for AAMDC Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around AAMDC on UCSC Golden Path with GeneCards custom track

Promoters for AAMDC Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around AAMDC on UCSC Golden Path with GeneCards custom track

Genomic Location for AAMDC Gene

77,821,107 bp from pter
77,918,432 bp from pter
97,326 bases
Plus strand

Genomic View for AAMDC Gene

Genes around AAMDC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AAMDC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AAMDC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AAMDC Gene

Proteins for AAMDC Gene

  • Protein details for AAMDC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Mth938 domain-containing protein
    Protein Accession:
    Secondary Accessions:
    • Q96AQ4
    • Q9Y6B1

    Protein attributes for AAMDC Gene

    122 amino acids
    Molecular mass:
    13332 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for AAMDC Gene

    Alternative splice isoforms for AAMDC Gene


neXtProt entry for AAMDC Gene

Proteomics data for AAMDC Gene at MOPED

Post-translational modifications for AAMDC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for AAMDC Gene

Domains & Families for AAMDC Gene

Protein Domains for AAMDC Gene


Suggested Antigen Peptide Sequences for AAMDC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the AAMDC family.
  • Belongs to the AAMDC family.
genes like me logo Genes that share domains with AAMDC: view

No data available for Gene Families for AAMDC Gene

Function for AAMDC Gene

Molecular function for AAMDC Gene

UniProtKB/Swiss-Prot Function:
May play a role in preadipocyte differentiation and adipogenesis.

Phenotypes for AAMDC Gene

genes like me logo Genes that share phenotypes with AAMDC: view

Animal Model Products

CRISPR Products

miRNA for AAMDC Gene

miRTarBase miRNAs that target AAMDC

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AAMDC Gene

Localization for AAMDC Gene

Subcellular locations from UniProtKB/Swiss-Prot for AAMDC Gene

Cytoplasm. Note=Diffuse distribution with some highly concentrated spots around the nucleus. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for AAMDC Gene COMPARTMENTS Subcellular localization image for AAMDC gene
Compartment Confidence
cytosol 3
nucleus 3
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for AAMDC Gene

Pathways & Interactions for AAMDC Gene

SuperPathways for AAMDC Gene

No Data Available

Gene Ontology (GO) - Biological Process for AAMDC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043066 negative regulation of apoptotic process IBA --
GO:0045600 positive regulation of fat cell differentiation IBA --
genes like me logo Genes that share ontologies with AAMDC: view

No data available for Pathways by source and SIGNOR curated interactions for AAMDC Gene

Drugs & Compounds for AAMDC Gene

No Compound Related Data Available

Transcripts for AAMDC Gene

Unigene Clusters for AAMDC Gene

Adipogenesis associated, Mth938 domain containing:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AAMDC Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
SP1: - -
SP2: - - -
SP3: - - -

Relevant External Links for AAMDC Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AAMDC Gene

mRNA expression in normal human tissues for AAMDC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for AAMDC Gene

SOURCE GeneReport for Unigene cluster for AAMDC Gene Hs.745040

genes like me logo Genes that share expression patterns with AAMDC: view

Protein tissue co-expression partners for AAMDC Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for AAMDC Gene

Orthologs for AAMDC Gene

This gene was present in the common ancestor of chordates.

Orthologs for AAMDC Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia AAMDC 35
  • 90.71 (n)
  • 89.34 (a)
  • 89 (a)
(Canis familiaris)
Mammalia AAMDC 35
  • 92.35 (n)
  • 87.7 (a)
  • 88 (a)
(Mus musculus)
Mammalia Aamdc 35
  • 90.71 (n)
  • 91.8 (a)
Aamdc 16
Aamdc 36
  • 75 (a)
(Pan troglodytes)
Mammalia C11H11orf67 35
  • 99.73 (n)
  • 100 (a)
  • 73 (a)
(Rattus norvegicus)
Mammalia Aamdc 35
  • 90.16 (n)
  • 89.34 (a)
(Monodelphis domestica)
Mammalia AAMDC 36
  • 84 (a)
(Gallus gallus)
Aves C1H11ORF67 35
  • 80.6 (n)
  • 86.07 (a)
C1H11ORF67 36
  • 86 (a)
(Anolis carolinensis)
Reptilia AAMDC 36
  • 82 (a)
(Danio rerio)
Actinopterygii aamdc 35
  • 70.49 (n)
  • 76.23 (a)
aamdc 36
  • 76 (a)
Species with no ortholog for AAMDC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for AAMDC Gene

Gene Tree for AAMDC (if available)
Gene Tree for AAMDC (if available)

Paralogs for AAMDC Gene

genes like me logo Genes that share paralogs with AAMDC: view

No data available for Paralogs for AAMDC Gene

Variants for AAMDC Gene

Sequence variations from dbSNP and Humsavar for AAMDC Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs2186564 - 77,872,220(-) CCGCA(C/T)ATCAA reference, missense
rs584601 -- 77,829,415(-) gaccc(A/C)aatgg intron-variant
rs584732 -- 77,863,559(+) AATTT(C/T)TGTAA intron-variant
rs585172 -- 77,863,651(+) CCCAA(A/T)GTGCT intron-variant
rs585721 -- 77,842,592(+) GGGGG(C/T)AGTCG reference, synonymous-codon

Variation tolerance for AAMDC Gene

Residual Variation Intolerance Score: 56.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.01; 80.08% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for AAMDC Gene

Disorders for AAMDC Gene

Relevant External Links for AAMDC

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for AAMDC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AAMDC Gene

Publications for AAMDC Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress. (PMID: 24797263) Tong J. … Moran M.F. (Mol. Cell Proteomics 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for AAMDC Gene

Sources for AAMDC Gene