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Aliases for AAED1 Gene

Aliases for AAED1 Gene

  • AhpC/TSA Antioxidant Enzyme Domain Containing 1 2 3
  • AhpC/TSA Antioxidant Enzyme Domain-Containing Protein 1 3 4
  • C9orf21 3 4
  • Chromosome 9 Open Reading Frame 21 2
  • Thioredoxin-Like Protein AAED1 3
  • UPF0308 Protein C9orf21 3

External Ids for AAED1 Gene

Previous Symbols for AAED1 Gene

  • C9orf21

Summaries for AAED1 Gene

GeneCards Summary for AAED1 Gene

AAED1 (AhpC/TSA Antioxidant Enzyme Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AAED1 Gene

Genomics for AAED1 Gene

Genomic Location for AAED1 Gene

Start:
96,639,577 bp from pter
End:
96,655,317 bp from pter
Size:
15,741 bases
Orientation:
Minus strand

Genomic View for AAED1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AAED1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AAED1 Gene

No data available for Regulatory Elements for AAED1 Gene

Proteins for AAED1 Gene

  • Protein details for AAED1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTV5-AAED1_HUMAN
    Recommended name:
    Thioredoxin-like protein AAED1
    Protein Accession:
    Q7RTV5
    Secondary Accessions:
    • B2RMW4
    • Q5JU02

    Protein attributes for AAED1 Gene

    Size:
    226 amino acids
    Molecular mass:
    24857 Da
    Quaternary structure:
    No Data Available

neXtProt entry for AAED1 Gene

Proteomics data for AAED1 Gene at MOPED

Post-translational modifications for AAED1 Gene

No Post-translational modifications

Other Protein References for AAED1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for AAED1 Gene

Domains for AAED1 Gene

Protein Domains for AAED1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

AAED1_HUMAN
Family:
  • Belongs to the AAED1 family.:
    • Q7RTV5
genes like me logo Genes that share domains with AAED1: view

No data available for Gene Families for AAED1 Gene

Function for AAED1 Gene

Gene Ontology (GO) - Molecular Function for AAED1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016209 antioxidant activity --
GO:0016491 oxidoreductase activity --
genes like me logo Genes that share ontologies with AAED1: view

Phenotypes for AAED1 Gene

GenomeRNAi human phenotypes for AAED1:
genes like me logo Genes that share phenotypes with AAED1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AAED1 Gene

Localization for AAED1 Gene

No data available for Gene Ontology (GO) - Cellular Components for AAED1 Gene

Pathways for AAED1 Gene

SuperPathways for AAED1 Gene

No Data Available

Interacting Proteins for AAED1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000364382%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000364382 for AAED1 Gene via STRING

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for AAED1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process --
genes like me logo Genes that share ontologies with AAED1: view

No data available for Pathways by source for AAED1 Gene

Transcripts for AAED1 Gene

mRNA/cDNA for AAED1 Gene

Unigene Clusters for AAED1 Gene

AhpC/TSA antioxidant enzyme domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AAED1 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: -
SP2: - - -
SP3:

Relevant External Links for AAED1 Gene

GeneLoc Exon Structure for
AAED1
ECgene alternative splicing isoforms for
AAED1

Expression for AAED1 Gene

mRNA expression in normal human tissues for AAED1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for AAED1 Gene

SOURCE GeneReport for Unigene cluster for AAED1 Gene Hs.44640

genes like me logo Genes that share expressions with AAED1: view

Orthologs for AAED1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for AAED1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AAED1 36
  • 99.41 (n)
  • 99.12 (a)
AAED1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia AAED1 36
  • 90.86 (n)
  • 91.15 (a)
AAED1 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia AAED1 36
  • 90.62 (n)
  • 87.95 (a)
AAED1 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Aaed1 36
  • 86.79 (n)
  • 90.09 (a)
Aaed1 16
Aaed1 37
  • 88 (a)
OneToOne
chicken
(Gallus gallus)
Aves AAED1 37
  • 66 (a)
OneToOne
C9ORF21 36
  • 73.05 (n)
  • 75 (a)
lizard
(Anolis carolinensis)
Reptilia AAED1 37
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia aaed1 36
  • 61.65 (n)
  • 54.87 (a)
Str.4655 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.215 36
zebrafish
(Danio rerio)
Actinopterygii AAED1 37
  • 54 (a)
OneToOne
Dr.16712 36
LOC100332791 36
  • 58.86 (n)
  • 55.41 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G37240 36
  • 45.34 (n)
  • 32.26 (a)
rice
(Oryza sativa)
Liliopsida Os03g0284600 36
  • 42.56 (n)
  • 31.28 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10381 37
  • 32 (a)
OneToOne
Species with no ortholog for AAED1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rat (Rattus norvegicus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for AAED1 Gene

ENSEMBL:
Gene Tree for AAED1 (if available)
TreeFam:
Gene Tree for AAED1 (if available)

Paralogs for AAED1 Gene

Selected SIMAP similar genes for AAED1 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for AAED1 Gene

genes like me logo Genes that share paralogs with AAED1: view

No data available for Paralogs for AAED1 Gene

Variants for AAED1 Gene

Sequence variations from dbSNP and Humsavar for AAED1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1129517 -- 96,641,272(+) TTTGG(G/T)GTTTA utr-variant-3-prime
rs6477597 -- 96,644,468(+) GCTTA(C/T)AGTCG intron-variant
rs6477600 -- 96,648,479(+) atttt(C/T)aGTGC intron-variant
rs7029007 -- 96,640,689(+) tagcc(A/G)ggcgt downstream-variant-500B
rs7046055 -- 96,640,900(+) AATAC(A/G)TATCT downstream-variant-500B, utr-variant-3-prime

Relevant External Links for AAED1 Gene

HapMap Linkage Disequilibrium report
AAED1

No data available for Structural Variations from Database of Genomic Variants (DGV) for AAED1 Gene

Disorders for AAED1 Gene

No disorders were found for AAED1 Gene.

No data available for UniProtKB/Swiss-Prot for AAED1 Gene

Publications for AAED1 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  2. Fugu and human sequence comparison identifies novel human genes and conserved non-coding sequences. (PMID: 12234665) Gilligan P. … Venkatesh B. (Gene 2002) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution. (PMID: 14710190) Castellano S. … GuigA^ R. (EMBO Rep. 2004) 3
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3

Products for AAED1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate AAED1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for AAED1
    • Block miRNA regulation of AAED1 using miScript Target Protectors

    Sources for AAED1 Gene

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