V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

AAAS Gene

protein-coding GIFtS: 57

GC12M051987

achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AAA ^², ⁵
AAASb ^²
ADRACALA ^², ³
ADRACALIN ^²
ALADIN ^²
Adracalin ^³
DKFZp586G1624 ^²
GL003 ^²

Descriptions
achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A) ^²

External Ids
HGNC: 13666¹
Entrez Gene: 8086²
UniProtKB: Q9NRG9³
Ensembl: ENSG00000094914⁷

Search outside databases for aliases for AAAS gene

Previous GC identifers: GC12P053994 GC12P053789 GC12M053417

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AAAS_HUMAN, Q9NRG9

Function: Plays a role in the normal development of the peripheral and central nervous system

Gene Wiki entry for AAAS

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the AAAS gene

Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q13.13 HGNC cytogenetic band: 12q13

AAAS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M051987: (about GC identifiers)

Start:	51,987,507 bp from pter
End:	52,001,648 bp from pter
Size:	14,142 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.10 NT_029419.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: AAAS_HUMAN, Q9NRG9 (See protein sequence)

Recommended Name: Aladin

Size: 546 amino acids; 59574 Da

Secondary accessions: Q9NWI6 Q9UG19

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_056480.1

ENSEMBL proteins:

ENSP00000209873 ENSP00000377908

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Adracalin)
	Human Recombinant Proteins from Abnova (AAAS)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005643	colocalizes with nuclear pore	IDA	12730363

About this table

Antibodies for AAAS:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for AAAS
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Adracalin), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (AAAS)
	Novus Biologicals Antibodies for AAAS

Assays for AAAS:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9NRG9

ProtoNet protein and cluster: Q9NRG9

UniProtKB/Swiss-Prot: AAAS_HUMAN, Q9NRG9

Similarity: Contains 4 WD repeats

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (AAAS)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (AAAS)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_015665

Applied Biosystems Silencer® siRNAs for AAAS

Sigma-Aldrich siRNA for AAAS

Sigma-Aldrich shRNA for AAAS

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for AAAS
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_015665
Myc/DDK tagged cDNA clone in CMV expression vector: NM_015665
untagged cDNA clones in CMV expression vector (see all 2): NM_015665

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_015665

UniProtKB/Swiss-Prot: AAAS_HUMAN, Q9NRG9

Function: Plays a role in the normal development of the peripheral and central nervous system

8 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Aaas):

behavior/neurological	cellular	digestive/alimentary	endocrine/exocrine gland	growth/size
homeostasis/metabolism	nervous system	reproductive system

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/52 Interacting proteins for AAAS (ENSP00000209873³) via UniProtKB, MINT, and/or STRING (see all 52 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IPO7	ENSP00000369042³	STRING (score=.931)
AGFG1	ENSP00000312059³	STRING (score=.899)
DDX19B	ENSP00000288071³	STRING (score=.899)
EIF5AL1	ENSP00000336702³	STRING (score=.899)
GLE1	ENSP00000308622³	STRING (score=.899)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0046822	regulation of nucleocytoplasmic transport	NAS	12730363

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for AAAS
1 Novoseek chemical compound relationship for AAAS gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
acth	57.79	3	18426811 (2), 18279781 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (AAAS)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (AAAS)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_015665

Sigma-Aldrich siRNA for AAAS

Sigma-Aldrich shRNA for AAAS

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_015665

REFSEQ mRNAs for AAAS gene:

NM_015665.5

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_015665

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_015665
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_015665
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_015665

Additional cDNA sequence:

AF226048.1 AJ289857.1 AK000833.1 AK094302.1 AK222509.1 AK293342.1 AL110160.1 AY237818.1

BC000659.2 BC018836.2 BT006912.1 CR590678.1 CR591048.1 CR593907.1 CR595976.1 CR597176.1

CR597994.1 CR601072.1 CR601632.1 CR616332.1 CR619164.1

20 DOTS entries:

DT.416286 DT.95167303 DT.75103801 DT.121180914 DT.100846216 DT.100846222 DT.40259973 DT.65284108

DT.121180939 DT.95167301 DT.100029444 DT.92439335 DT.100758722 DT.121180903 DT.121180929 DT.416284

DT.92439331 DT.95167299 DT.95167302 DT.97850238

24/372 AceView cDNA sequences (see all 372 ):

BE797091 BQ009784 CR597176 AL550148 BQ084010 BI829100 CB123646 BP366407

BI761621 BM552143 CR593907 BQ051486 BU631921 BU153912 CR597994 AI140344

CR601072 AW340290 BQ929947 BU579732 BQ879190 BM762954 BQ685495 BQ687774

highest scoring ESTs for AAAS:

AF226048 AI763061 AI880283 AK000833 AL515777 AL525649 AL552409 AL559497 BC000659 BC018836

Unigene Cluster for AAAS:

Achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)

Hs.369144 [show with all ESTs]

Unigene Representative Sequence: AK094302

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for AAAS (see all 12 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2a	·	2b	·	2c	^	3a	·	3b	·	3c	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7	^	8a	·	8b	·	8c	^	9	^	10	^	11	^	12	^
SP1:													-		-						-		-				-				-								-
SP2:													-		-						-		-				-				-		-		-				-
SP3:																					-		-				-				-		-		-				-
SP4:
SP5:													-		-						-		-		-		-				-

ExUns:	13	^	14	^	15a	·	15b	^	16
SP1:							-
SP2:							-
SP3:							-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for AAAS

2 Ensembl transcripts including schematic representations:

ENST00000209873 ENST00000394384

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

AAAS expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for AAAS

¹ / ² / ³

3 probe-sets matching AAAS gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
65445_at²^{, 3}	U95-C	2	1.00	0.97	1.00	1.00	AI763061	0.80	1.00	0.91	1
218075_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_015665	0.60	1.00	0.82	1
218075_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ACCTGCCCCT

SOURCE GeneReport for Unigene cluster: Hs.369144
UniProtKB/Swiss-Prot: AAAS_HUMAN, Q9NRG9
Tissue specificity: Widely expressed. Particularly abundant expression is found in cerebellum,
corpus callosum, adrenal gland, pituary gland, gatsrointestinal structures and fetal lung

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for AAAS gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	AAAS¹	--	achalasia, adrenocortical insufficiency, alacrimia more	87.96(n) 93.65(a)	607867 XM_844704.1 XP_849797.1
chimpanzee (Pan troglodytes)	AAAS¹	--	achalasia, adrenocortical insufficiency, alacrimia more	99.63(n) 99.63(a)	467003 XM_522403.2 XP_522403.2
cow (Bos taurus)	AAAS¹	--	achalasia, adrenocortical insufficiency, alacrimia more	90.95(n) 96.15(a)	506561 NM_001075269.1 NP_001068737.1
mouse (Mus musculus)	Aaas^{1, 5}	15⁵	achalasia, adrenocortical insufficiency, alacrimia^{1, 5}	87.3(n)¹ 93.41(a)¹	223921¹ NM_153416.1¹ NP_700465.1¹ AK034591⁵ AK051635⁵ (see all 24)
zebrafish (Danio rerio)	aaas²	--	achalasia, adrenocortical insufficiency, alacrimia	74.03(n)	378454 AL911339.1

About this table Species with no ortholog for AAAS

ENSEMBL Gene Tree for AAAS

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/90 NCBI SNPs in AAAS are shown (see all 90 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 31)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10747666^1,2	A,C,F,H	52003103(+)	`AGAGCA/GAGACC`	1	--	ng3¹ tfbs³		2		EU WA	216
--	rs11540349^1,2	C,H	52000707(-)	`AGGATC/TCCCTA`	1	P/S	mis¹ ese³		8		EU EA WA	812
--	rs4759213^1,2	C	52003267(-)	`tggctA/Ggtttt`	1	--	ng3¹		0	--	--	--	--
--	rs11540352^1,2	H	52000655(-)	`CATCCA/GTCACC`	1	H/R	mis¹ ese³		4		EU EA WA	406
	rs1546808^1,2	C,F,H	51989288(-)	`TGGTTT/CCGAGG`	1	F/F	syn¹ ese³		8		MN EU EA WA NA	740
	rs11540353^1,2	C,F	51995177(-)	`GAAGAT/CCTGAT`	1	D/D	syn¹		1		NA	58
	rs4759281^1,2	A,C,F,H	51990122(-)	`TGGGCG/AGAGAG`	1	--	int¹		4		EU EA WA	416
	rs4759021^1,2	A,C,F,H	52001135(-)	`GGATGC/TGGGAG`	1	--	int¹		4		EU EA WA	418
	rs10783567^1,2	A,C,F,H	51991970(+)	`CCCCCT/CCCAAA`	1	--	int¹		4		EU EA WA	408
--	rs10876426^1,2	A,C,H	51997530(+)	`GTGAAC/TTCGGG`	1	--	int¹		4		EU EA WA	410

About this table

HapMap Linkage Disequilibrium images for AAAS (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605378 disorders: 231550

UniProtKB/Swiss-Prot: AAAS_HUMAN, Q9NRG9

Defects in AAAS are the cause of achalasia-addisonianism-alacrima syndrome (AAAS)

[MIM:231550]; also known as triple-A syndrome or Allgrove syndrome. AAAS is an autosomal recessive

disorder characterized by adreno-corticotropic hormone (ACTH)-resistant adrenal failure, achalasia

of the esophageal cardia and alacrima. The syndrome is associated with variable and progressive

neurological impairment involving the central, peripheral, and autonomic nervous system. Other

features such as palmoplantar hyperkeratosis, short stature, facial dysmorphy and osteoporosis may

also be present

4 Novoseek disease relationships for AAAS gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
alacrima	99.08	12	18628786 (2), 15680696 (1), 15690314 (1), 19172511 (1) (see all 9)
allgrove syndrome	98.41	22	17880786 (3), 15516781 (2), 11062474 (1), 15217518 (1) (see all 15)
achalasia	92.46	13	18628786 (1), 15680696 (1), 15690314 (1), 19172511 (1) (see all 10)
neurological disorders	41.13	7	15680696 (1), 15690314 (1), 18662670 (1), 12429595 (1) (see all 5)

About this table

Human Gene Mutation Database: AAAS

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/70 PubMed articles for AAAS gene (see all 70 ):

Mutant WD-repeat protein in triple-A syndrome. (PubMed id 11062474)^{1, 2, 3, 4} Tullio-Pelet A.... Lyonnet S. (2000)
Triple A syndrome is caused by mutations in AAAS, a new WD-repeat protein gene. (PubMed id 11159947)^{1, 3, 4} Handschug K....Huebner A. (2001)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The triple A syndrome is due to mutations in ALADIN, a novel member of the nuclear pore complex. (PubMed id 15666842)^{1, 3} Huebner A....Koehler K. (2004)
Spectrum of mutations of the AAAS gene in Allgrove syndrome: lack of mutations in six kindreds with isolated resistance to corticotropin. (PubMed id 11701718)^{1, 3} Sandrini F....Stratakis C.A. (2001)
Identification of the sites of expression of triple A syndrome mRNA in the rat using in situ hybridisation. (PubMed id 15680696)^{1, 3} Storr H.L....Michael G.J. (2005)
Genotypic heterogeneity and clinical phenotype in triple A syndrome: a review of the NIH experience 2000-2005. (PubMed id 16098009)^{1, 3} Brooks B.P....Stratakis C. (2005)
Triple A or Allgrove syndrome. A case report with ophthalmic abnormalities and a novel mutation in the AAAS gene. (PubMed id 19172511)^{1, 3} Villanueva-Mendoza C....Zenteno J.C. (2009)
Cellular localization of 17 natural mutant variants of ALADIN protein in triple A syndrome - shedding light on an unexpected splice mutation. (PubMed id 16609705)^{1, 3} Krumbholz M....Huebner A. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8086	HGNC: 13666	AceView: AAAS	Ensembl:ENSG00000094914	euGenes: HUgn8086
ECgene: AAAS	H-InvDB: AAAS

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
GeneReviews	http://www.genetests.org/query?gene=AAAS

Licensable Technologies for AAAS
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for AAAS:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for AAAS-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for AAAS		Antibodies for AAAS
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for AAAS		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (AAAS)
	Antibodies (AAAS)
	Chimera RNAi (AAAS)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Adracalin)
	Antibodies (Adracalin)

Search OriGene for AAAS

Search Tocris compounds for AAAS

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for AAAS

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
AAAS Gene at Home site.
Version 2.41.1
server5.xennexinc.com

AAAS Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for AAAS

Summaries
for AAAS

Genomic Location
for AAAS

Proteins
for AAAS

Protein Domains/
Families
for AAAS

Gene Function
for AAAS

Pathways & Interactions
for AAAS

Drugs & Compounds
for AAAS

Transcripts
for AAAS

Expression
for AAAS

Orthologs
for AAAS

Paralogs
for AAAS

SNPs/Variants
for AAAS

Disorders & Mutations
for AAAS

Medical News
for AAAS

Publications
for AAAS

Search for AAAS

Genome Databases showing AAAS

Other Databases showing AAAS

Specialized Databases showing AAAS

Licensable Technologies
for AAAS

Services
for AAAS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

AAAS Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor AAAS

Summariesfor AAAS

Genomic Locationfor AAAS

Proteinsfor AAAS

Protein Domains/Familiesfor AAAS

Gene Functionfor AAAS

Pathways & Interactionsfor AAAS

Drugs & Compoundsfor AAAS

Transcriptsfor AAAS

Expression for AAAS

Orthologsfor AAAS

Paralogsfor AAAS

SNPs/Variantsfor AAAS

Disorders & Mutationsfor AAAS

Medical Newsfor AAAS

Publicationsfor AAAS

Search for AAAS

Genome Databases showing AAAS

Other Databases showing AAAS

Specialized Databases showing AAAS

Licensable Technologiesfor AAAS

Servicesfor AAAS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for AAAS

Summaries
for AAAS

Genomic Location
for AAAS

Proteins
for AAAS

Protein Domains/
Families
for AAAS

Gene Function
for AAAS

Pathways & Interactions
for AAAS

Drugs & Compounds
for AAAS

Transcripts
for AAAS

Expression
for AAAS

Orthologs
for AAAS

Paralogs
for AAAS

SNPs/Variants
for AAAS

Disorders & Mutations
for AAAS

Medical News
for AAAS

Publications
for AAAS

Licensable Technologies
for AAAS

Services
for AAAS