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Aliases for A2MP1 Gene

Aliases for A2MP1 Gene

  • Alpha-2-Macroglobulin Pseudogene 1 2 3
  • Pregnancy-Zone Protein Pseudogene 3
  • Alpha-2-Macroglobulin Pseudogene 2
  • A2MP 3

External Ids for A2MP1 Gene

Previous HGNC Symbols for A2MP1 Gene

  • A2MP

Previous GeneCards Identifiers for A2MP1 Gene

  • GC12M009384

Summaries for A2MP1 Gene

GeneCards Summary for A2MP1 Gene

A2MP1 (Alpha-2-Macroglobulin Pseudogene 1) is a Pseudogene. Diseases associated with A2MP1 include alzheimer disease.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for A2MP1 Gene

Genomics for A2MP1 Gene

Genomic Location for A2MP1 Gene

Start:
9,228,533 bp from pter
End:
9,275,817 bp from pter
Size:
47,285 bases
Orientation:
Minus strand

Genomic View for A2MP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for A2MP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for A2MP1 Gene

No data available for Regulatory Elements for A2MP1 Gene

Proteins for A2MP1 Gene

Post-translational modifications for A2MP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for A2MP1 Gene

Domains for A2MP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for A2MP1 Gene

Function for A2MP1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for A2MP1 Gene

Localization for A2MP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for A2MP1 Gene

Pathways for A2MP1 Gene

SuperPathways for A2MP1 Gene

No Data Available

Interacting Proteins for A2MP1 Gene

Gene Ontology (GO) - Biological Process for A2MP1 Gene

None

No data available for Pathways by source for A2MP1 Gene

Transcripts for A2MP1 Gene

mRNA/cDNA for A2MP1 Gene

(1) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for A2MP1 Gene

Alpha-2-macroglobulin pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for A2MP1 Gene

No ASD Table

Relevant External Links for A2MP1 Gene

GeneLoc Exon Structure for
A2MP1
ECgene alternative splicing isoforms for
A2MP1

Expression for A2MP1 Gene

mRNA expression in normal human tissues for A2MP1 Gene

SOURCE GeneReport for Unigene cluster for A2MP1 Gene Hs.569125

genes like me logo Genes that share expressions with A2MP1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for A2MP1 Gene

Orthologs for A2MP1 Gene

Evolution for A2MP1 Gene

ENSEMBL:
Gene Tree for A2MP1 (if available)
TreeFam:
Gene Tree for A2MP1 (if available)

No data available for Orthologs for A2MP1 Gene

Paralogs for A2MP1 Gene

No data available for Paralogs for A2MP1 Gene

Variants for A2MP1 Gene

Sequence variations from dbSNP and Humsavar for A2MP1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs34362 -- 9,232,829(+) GATAT(C/T)TGACA intron-variant
rs2059758 -- 9,228,533(+) GAGTT(A/G)TAAAT nc-transcript-variant
rs7301712 -- 9,229,991(+) CTTTA(G/T)AGGGA intron-variant
rs7315222 -- 9,233,614(+) CTTCC(A/G)CAGAG nc-transcript-variant
rs7952958 -- 9,230,632(+) Ctttt(C/T)tcttc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for A2MP1 Gene

Variant ID Type Subtype PubMed ID
nsv527404 CNV Gain 19592680
nsv523958 CNV Loss 19592680
dgv466e1 CNV Complex 17122850
nsv8903 CNV Loss 18304495
esv992832 CNV Insertion 20482838

Relevant External Links for A2MP1 Gene

HapMap Linkage Disequilibrium report
A2MP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for A2MP1 Gene

Disorders for A2MP1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for A2MP1 Gene including...

Search for A2MP1 Gene in MalaCards »

Relevant External Links for A2MP1

Genetic Association Database (GAD)
A2MP1
Human Genome Epidemiology (HuGE) Navigator
A2MP1
genes like me logo Genes that share disorders with A2MP1: view

No data available for UniProtKB/Swiss-Prot for A2MP1 Gene

Publications for A2MP1 Gene

  1. An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. (PMID: 19105203) Edwards T.L. … Ritchie M.D. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009) 3 48
  2. A cluster of alpha 2-macroglobulin-related genes (alpha 2 M) on human chromosome 12p: cloning of the pregnancy-zone protein gene and an alpha 2M pseudogene. (PMID: 2478422) Devriendt K. … Marynen P. (Gene 1989) 2 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Recombinant soluble glypican 3 protein inhibits the growth of hepatocellular carcinoma in vitro. (PMID: 20617511) Feng M. … Ho M. (Int. J. Cancer 2011) 3
  5. Activator-independent transcription of Snf1-dependent genes in mutants lacking histone tails. (PMID: 21338416) Infante J.J. … Young E.T. (Mol. Microbiol. 2011) 3

Products for A2MP1 Gene

Sources for A2MP1 Gene

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