A1CF Gene
protein-coding GIFtS : 52
GCID: GC10 M052566
APOBEC1 complementation factor
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Aliasesfor A1CF gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases APOBEC1 Complementation Factor 1 2 APOBEC1CF1 2 ACF1 2 3 Apo-B RNA Editing Protein2 ASP1 2 3 Apobec-1 Complementation Factor (ACF) (ASP)2 ACF641 2 APOBEC-1 Stimulating Protein2 ACF651 2 APOBEC1-Stimulating Protein3
Export aliases for A1CF gene to outside databases Previous GC identifers: GC10M052237 GC10M046544
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Summariesfor A1CF gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for A1CF : Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. (provided by RefSeq, Nov 2010) UniProtKB/Swiss-Prot: A1CF_HUMAN, Q9NQ94 Function : Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for thepostranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay Gene Wiki entry for A1CF (ACF)
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Genomic Viewsfor A1CF gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000010.10 NC_018921.1 NT_030059.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the A1CF gene promoter: Arnt RORalpha2 RORalpha1 POU2F1 POU2F1b POU2F1a STAT3 FOXO1a POU2F1c FOXO1 Other transcription factors Search SABiosciences Chromatin IP Primers for A1CF Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat A1CF
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10q11.23 Ensembl cytogenetic band: 10q11.23 HGNC cytogenetic band: 10q21.1 A1CF Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10M052566: view genomic region
(about GC identifiers )
Start:
52,566,322 bp from pter
End:
52,645,435 bp from pter
Size:
79,114 bases
Orientation:
minus strand
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Proteinsfor A1CF gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: A1CF_HUMAN, Q9NQ94 (See
protein sequence )Recommended Name: APOBEC1 complementation factor Size : 594 amino acids; 65202 Da
Subunit : Part of the apolipoprotein B mRNA editing complex with APOBEC1. Interacts with TNPO2; TNPO2 may be responsiblefor transport of A1CF into the nucleus. Interacts with SYNCRIP. Interacts with CELF2/CUGBP2 (By similarity)
Subcellular location : Nucleus. Endoplasmic reticulum (By similarity). Cytoplasm. Note=Predominantly nuclear where itlocalizes to heterochromatin. Also cytoplasmic where it is found at the outer surface of the endoplasmic reticulum (By similarity). Shuttles between the nucleus and cytoplasm. May be transported into the nucleus by the nuclear import protein TNPO2/TRN2 or by APOBEC1
Sequence caution : Sequence=BAA91086.1; Type=Frameshift; Positions=148;
1 PDB 3D structure from and Proteopedia for A1CF :2CPD (3D)
 
Secondary accessions : A1L4F2 A8K7G7 B7ZM14 Q5SZQ0 Q9NQ93 Q9NQX8 Q9NQX9 Q9NXC9 Q9NZD3Alternative splicing : 6 isoforms : Q9NQ94-1 Q9NQ94-2 Q9NQ94-3 Q9NQ94-4 Q9NQ94-5 Q9NQ94-6 (Minor isoform found in 2-3% of cDNA clones)Explore the universe of human proteins at neXtProt for A1CF: NX_Q9NQ94 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9NQ94 A1CF Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (6 alternative transcripts):
NP_001185747.1 NP_001185748.1 NP_001185749.1 NP_055391.2 NP_620310.1 NP_620311.1 ENSEMBL proteins: ENSP00000363113 ENSP00000363105 ENSP00000363109 ENSP00000363107 ENSP00000397953 ENSP00000282641 ENSP00000378873 ENSP00000378868 Reactome Protein details: Q9NQ94 Human Recombinant Protein Products: Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6 ): About this table
A1CF for ontologies About GeneDecksing A1CF Antibody Products: Assay Products for A1CF:
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Protein
Domains / Familiesfor A1CF gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
A1CF for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q9NQ94 ProtoNet protein and cluster: Q9NQ94
1 Blocks protein family : IPB000504 RNA-binding region RNP-1 (RNA recognition motif) UniProtKB/Swiss-Prot: A1CF_HUMAN, Q9NQ94 Domain : The RRM domains are necessary but not sufficient for binding to APOB mRNA. Additional residues in the pre-RRMand C-terminal regions are required for RNA-binding and for complementing APOBEC1 activity Similarity : Contains 3 RRM (RNA recognition motif) domains
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Functionfor A1CF gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: A1CF_HUMAN, Q9NQ94 Function : Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for thepostranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for A1CF (see all 6 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for A1CF (see all 3 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 6 ): A1CF (NM_138932 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for A1CF Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat A1CF
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for A1CF
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7 ): About this table
A1CF for ontologies About GeneDecksing Animal Models: 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for A1cf) :
A1CF for phenotypes About GeneDecksing
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Pathways & Interactionsfor A1CF gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 Formation of editosomes by ADAR proteins 2 mRNA Splicing - Major Pathway 3 Generic Transcription Pathway
Pathway sources See GeneCards unified pathways Show all pathways 5
Reactome Pathways for A1CF
A1CF for pathways About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for A1CF STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)5/10 Interacting proteins for A1CF (Q9NQ94 3 ENSP00000282641 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 10 )About this table Gene Ontology (GO): 5 biological process terms (GO ID links to tree view) : About this table
A1CF for ontologies About GeneDecksing
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Drugs & Compoundsfor A1CF gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
A1CF for compounds About GeneDecksing Browse Tocris compounds for A1CF 1 HMDB Compound for A1CF About this table Compound Synonyms
CAS
# PubMed Ids Cytosine 4-Amino-2(1H)-pyrimidinone (see all 6 ) 71-30-7 --
4 Novoseek chemical compound relationships for A1CF gene About this table
Search CenterWatch for drugs/clinical trials and news about A1CF
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Transcriptsfor A1CF gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for A1CF gene (6 alternative transcripts): NM_001198818.1 NM_001198819.1 NM_001198820.1 NM_014576.3 NM_138932.2 NM_138933.2 Unigene Cluster for A1CF:
APOBEC1 complementation factor Hs.282795 [show with all ESTs ] Unigene Representative Sequence: NM_001198819 10 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000374001 ENST00000373993 ENST00000373997 (uc009xov.3 uc001jji.3 )ENST00000373995 (uc010qhn.2 uc001jjh.3 ) ENST00000493415 ENST00000473480 ENST00000414883 (uc001jjk.1 ) ENST00000282641 (uc001jjj.3 ) ENST00000395495 ENST00000395489 (uc010qho.2 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for A1CF (see all 6 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for A1CF (see all 3 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 6 ): A1CF (NM_138932 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for A1CF Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat A1CF
Additional cDNA sequence: AF209192.1 AF271789.1 AF271790.1 AJ272078.1 AJ272079.1 AK000324.1 AK130022.1 AK291982.1 AK303801.1 BC022263.1 BC054873.1 BC130519.1 BC144194.1 BC144196.1 CR749831.1
11 DOTS entries : DT.101966638 DT.92425892
DT.95374373 DT.100022638 DT.86841758 DT.100765861 DT.99940798 DT.95374372 DT.95374374 DT.95325400 DT.92425886 24/110 AceView cDNA sequences (see all 110 ):
CK825749 BF431668 CK825748 T39997 BC054873 NM_014576 CA942922 NM_138932 BG617808 T78557 CA942681 AJ272078 BM479119 AJ272079 AI913746 AF271789 NM_138933 T78476 BX101891 AV684607 AV660671 N77737 AW610448 BG618487 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for A1CF About this scheme ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 SP1 :   -             -     -         -         SP2 :         -       -     -         -         SP3 :         -       -     -                 SP4 :                                   SP5 :   -       -                          
ECgene alternative splicing isoforms for A1CF
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Expression for A1CF gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section A1CF expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image A1CF expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category Endoderm progenitor-like cells (Generation and expan... )Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See A1CF Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for A1CF SOURCE GeneReport for Unigene cluster: Hs.282795 UniProtKB/Swiss-Prot: A1CF_HUMAN, Q9NQ94 Tissue specificity : Widely expressed with highest levels in brain, liver, pancreas, colon and spleen SABiosciences Custom PCR Arrays for A1CF Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for A1CFBrowse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat A1CF QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat A1CF QIAGEN QuantiFast Probe-based Assays in human , mouse , rat A1CF In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for A1CF
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Orthologsfor A1CF gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for A1CF gene from 6/20 species (see all 20 ) About this table
ENSEMBL Gene Tree for A1CF (if available)TreeFam Gene Tree for A1CF (if available)
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Paralogsfor A1CF gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for A1CF gene RBM47 2 SYNCRIP 2 DND1 2 RBM46 2 HNRNPR 2 13 SIMAP similar genes for A1CF using alignment to 4 protein entries: A1CF_HUMAN (see all proteins ):RBM47 RBM46 HNRPR DKFZp686A13234 SYNCRIP HNRNPR DKFZp686C17209 DKFZp781C0423 DKFZp781I1140 DND1 RBM39 RBMY1A1 CELF1
A1CF for paralogs About GeneDecksing
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Genomic Variantsfor A1CF gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 10 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for A1CF (52566322 - 52645435 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for A1CF: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing A1CF
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Disorders
/ Diseasesfor A1CF gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
A1CF for disorders About GeneDecksing 6 diseases for A1CF : About MalaCards anisometropia hydrocele amblyopia cholera hepatocellular carcinoma carcinoma 2 diseases from the University of Copenhagen DISEASES database for A1CF :Amblyopia Anisometropia Export disorders for A1CF gene to outside databases
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Publicationsfor A1CF gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for A1CF gene, integrated from 9 sources (see all 30 ): (articles sorted by number of sources associating them with A1CF) Utopia : connect your pdf to the dynamic world of online information
A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling. (PubMed id 12896982) 1 , 2 , 9 Blanc V.... Davidson N.O. (2003) Molecular cloning of APOBEC-1 complementation factor, a novel RNA- binding protein involved in the editing of apolipoprotein B mRNA. (PubMed id 10669759) 1 , 2 , 9 Mehta A.... Driscoll D.M. (2000) Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing. (PubMed id 11815617) 1 , 3, 9 Dance G.S....Smith H.C. (2002) Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene. (PubMed id 11718896) 1 , 2 , 9 Henderson J.O.... Davidson N.O. (2001) Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing. (PubMed id 11871661) 1 , 2 , 9 Mehta A. and Driscoll D.M. (2002) The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay. (PubMed id 12881431) 1 , 2 , 9 Chester A.... Navaratnam N. (2003) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054) 1 , 2 Deloukas P.... Rogers J. (2004) Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing. (PubMed id 11134005) 1 , 2 Blanc V.... Davidson N.O. (2001) Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex. (PubMed id 10781591) 1 , 2 Lellek H.... Greeve J. (2000)
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Specialized Databases showing A1CF gene (According to PharmGKB ,
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PharmGKB entry for A1CF Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for A1CF gene: Search GeneIP for patents involving A1CF GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor A1CF gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for A1CF OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for A1CF OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for A1CF OriGene Protein Over-expression Lysate for A1CF Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for A1CF Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for A1CF OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for A1CF Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for A1CF OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat A1CF QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing A1CF QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat A1CF QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat A1CF QIAGEN QuantiFast Probe-based Assays in human , mouse , rat A1CF QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat A1CF
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A1CF Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for A1CF
ThermoFisher Antibody for A1CF
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat A1CF
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