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Aliases & Descriptions for A1BG
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| A1B 2 | | ABG 2 | | DKFZp686F0970 2 | | GAB 2 | | HYST2477 2 |
| | | Descriptions |
|---|
| alpha 1B-glycoprotein 2 | | alpha-1-B glycoprotein 2, 3 |
|
| | Search outside databases for aliases for A1BG genePrevious GC identifers: GC19M059755 GC19M059310 GC19M063532 |
Summaries for A1BG(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for A1BG: The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. [provided by RefSeq]
|
Genomic Location for A1BG
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19qA1BG Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M063548:
(about GC identifiers)
Start:
|
63,548,356 bp from pter |
End:
|
63,556,669 bp from pter |
Size:
|
8,314 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000019.8 NT_011109.15
| Proteins for A1BG
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: A1BG_HUMAN, P04217 (See
protein sequence)Recommended Name: Alpha-1B-glycoprotein precursor Size: 495 amino acids; 54273 Da
Subcellular location: Secreted
Secondary accessions: Q68CK0 Q8IYJ6 Q96P39REFSEQ proteins: NP_570602.2
ENSEMBL proteins: ENSP00000263100
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
1 Gene Ontology (GO) cellular component term (links to tree view): About this table
Antibodies for A1BG: Assays for A1BG: | Protein
Domains/ Families for A1BG(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P04217
ProtoNet protein and cluster: P04217 1 Blocks protein family: IPB003598 Immunoglobulin C-2 type
UniProtKB/Swiss-Prot: A1BG_HUMAN, P04217Similarity: Contains 5 Ig-like V-type (immunoglobulin-like) domains | Gene Function for A1BG
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_130786
Applied Biosystems Silencer® siRNAs for A1BG
Sigma-Aldrich siRNA and siRNA Panels for A1BG  Sigma-Aldrich shRNA for A1BG  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_130786                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_130786                                  untagged cDNA clones in CMV expression vector (see all 2): NM_130786 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_130786
Genatlas biochemistry entry for A1BG:glycoprotein,alpha-1-B-1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | About this table | Pathways & Interactions for A1BG
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5/34 Interacting proteins for A1BG (ENSP000002631003) via UniProtKB, MINT, and/or STRING (see all 34
)About this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- | About this table
|
Drugs & Compounds for A1BG(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for A1BG
|
Transcripts for A1BG(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_130786
Sigma-Aldrich siRNA and siRNA Panels for A1BG  Sigma-Aldrich shRNA for A1BG  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_130786 REFSEQ mRNAs for A1BG gene: NM_130786.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_130786               OriGene GFP tagged cDNA clone in CMV expression vector: NM_130786                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_130786                                  untagged cDNA clones in CMV expression vector (see all 2): NM_130786  Additional cDNA sequence: AB073611.1 AF414429.1 AK055885.1 AK056201.1 AK289417.1 BC035719.1 BX537419.1 CR603363.1 CR604603.1 CR609084.1 CR612720.1 CR614062.1 8 DOTS entries: DT.95230508 DT.207949 DT.100768640 DT.97823153 DT.121451092 DT.100878023 DT.100878029 DT.100878031 24/152 AceView cDNA sequences (see all 152
):CB163551 CB162205 CB135246 AB073611 CB130088 CR614062 CB138231 CB141199 CR612720 CR603363 CR609084 AW470952 CB148792 BM153273 CB121414 CR604603 CB130068 BF196450 CB144216 CB130078 CB163893 BX410165 CB134894 BU740127
highest scoring ESTs for A1BG:AF414429 AI022193 AK055885 AL531425 BC035719 BM545070 BX325176 BX346032 BX422371 BX427184 Unigene Cluster for A1BG: Alpha-1-B glycoprotein Hs.529161 [show with all ESTs]Unigene Representative Sequence: AK055885
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for A1BG
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for A1BG
1 Ensembl transcript including schematic representation: ENST00000263100
|
Expression for A1BG
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| A1BG expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for A1BG
1 / 2 / 3 3 probe-sets matching A1BG gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: ACAACCAAAA
SOURCE GeneReport for Unigene cluster: Hs.529161 UniProtKB/Swiss-Prot: A1BG_HUMAN, P04217Tissue specificity: Plasma |
Orthologs for A1BG
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for A1BG gene from 5 species
About this table Species with no ortholog for A1BG
ENSEMBL Gene Tree for A1BG | Paralogs for A1BG(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for A1BG gene
- OSCAR2 NCR12 IGSF12 FCAR2 GP62
|
SNPs/Variants for A1BG(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for A1BG (up to first 250kb)
|
Disorders & Mutations for A1BG
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 138670
|
Medical News for A1BG(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for A1BG (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/28 PubMed articles for A1BG gene (see all 28
):- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)3, 4 Liu T.... Smith R.D. (2005)
- Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)3, 4 Yamada S....Nakagawara A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. (PubMed id 14760718)3, 4 Bunkenborg J.... Wisniewski J.R. (2004)
- Linkage between alpha 1B-glycoprotein (A1BG) and Lutheran (LU) red blood group system: assignment to chromosome 19: new genetic variants of A1BG. (PubMed id 2591067)2, 3 Eiberg H....Mohr J. (1989)
- Amino acid sequence of human plasma alpha 1B-glycoprotein: homology to the immunoglobulin supergene family. (PubMed id 3458201)3, 4 Ishioka N.... Putnam F.W. (1986)
- Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. (PubMed id 15461460)1, 3 Udby L....Kjeldsen L. (2004)
- Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients. (PubMed id 18706098)3 Tian M....Han J.X. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)3 Ota T....Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
|
Search for A1BG
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing A1BG
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing A1BG
(According to HUGE)
About This Section
| -- |
Specialized Databases showing A1BG(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| SHMPD | http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=alpha1B |
|
| | | About This Section
| --
| Services for A1BG(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for A1BG:

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| | Recombinant Proteins (A1BG) | | Antibodies (A1BG) |
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