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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

61E3.4 Gene

protein-coding   GIFtS: 20
GCID: GC16M021847          (predicted)

61E3.4


  Search for 61E3.4
in our new
 Human Malady Compendium 
Biological research products
for 61E3.4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Nuclear Pore Complex Interacting Protein-Like2
NPIPL34
Protein 61E3.44
Uncharacterized Protein4

External Ids:    Entrez Gene: 4403452   Ensembl: ENSG000001858647   UniProtKB: E5RHP94   UniProtKB: E7ENX14   UniProtKB: E9PKP14   
UniProtKB: F5GW904   UniProtKB: F5GWQ44   UniProtKB: F5GXZ64   UniProtKB: F5GYP34   UniProtKB: F5GZP94   
UniProtKB: F5H6Y64   UniProtKB: F5H6Z54   UniProtKB: F5H7Q74   UniProtKB: H0YIQ54   UniProtKB: H3BQU54   

Export aliases for 61E3.4 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for 61E3.4
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for 61E3.4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat 61E3.4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.2   Ensembl cytogenetic band:  16p12.2   

61E3.4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
61E3.4 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M021847:  view genomic region     (about GC identifiers)

Start:
21,845,884 bp from pter      End:
21,892,148 bp from pter
Size:
46,265 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/TrEMBL: E5RHP9 (See protein sequence)
Recommended Name: Nuclear pore complex-interacting protein-like 3  
Size: 49 amino acids; 5676 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data
Secondary accessions: E7EQ51

UniProtKB/TrEMBL: E7ENX1 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 661 amino acids; 74088 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: E9PKP1 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 595 amino acids; 65915 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5GW90 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 420 amino acids; 45766 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5GWQ4 (See protein sequence)

Recommended Name: Nuclear pore complex-interacting protein-like 3  
Size: 40 amino acids; 4627 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5GXZ6 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 11 amino acids; 1229 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5GYP3 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 78 amino acids; 8909 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5GZP9 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 14 amino acids; 1576 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5H6Y6 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 120 amino acids; 13965 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5H6Z5 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 104 amino acids; 11927 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: F5H7Q7 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 834 amino acids; 92250 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: H0YIQ5 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 68 amino acids; 7929 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

UniProtKB/TrEMBL: H3BQU5 (See protein sequence)

Recommended Name: Protein 61E3.4  
Size: 84 amino acids; 9683 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as
preliminary data

61E3.4 Protein expression data from MOPED and PaxDb:    About this image 
61E3.4 Protein Expression

ENSEMBL proteins: 
 ENSP00000442776   ENSP00000339196   ENSP00000429543   ENSP00000439732   ENSP00000429523  
 ENSP00000439720   ENSP00000433301   ENSP00000442065   ENSP00000443445   ENSP00000404439  
 ENSP00000349936   ENSP00000392155   ENSP00000439166  

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Uscn Proteins for 61E3.4


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Uscn ELISAs and CLIAs for 61E3.4


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

61E3.4 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR009443 NPIP

Graphical View of Domain Structure for InterPro Entry E5RHP9
Graphical View of Domain Structure for InterPro Entry E7ENX1
Graphical View of Domain Structure for InterPro Entry E9PKP1
Graphical View of Domain Structure for InterPro Entry F5GW90
Graphical View of Domain Structure for InterPro Entry F5GWQ4
Graphical View of Domain Structure for InterPro Entry F5GXZ6
Graphical View of Domain Structure for InterPro Entry F5GYP3
Graphical View of Domain Structure for InterPro Entry F5GZP9
Graphical View of Domain Structure for InterPro Entry F5H6Y6
Graphical View of Domain Structure for InterPro Entry F5H6Z5
Graphical View of Domain Structure for InterPro Entry F5H7Q7
Graphical View of Domain Structure for InterPro Entry H0YIQ5
Graphical View of Domain Structure for InterPro Entry H3BQU5

ProtoNet protein and cluster: E5RHP9


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Animal Models:
   inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for 61E3.4 

miRNA
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In Situ Assay
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for 61E3.4

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for 61E3.4
Search CenterWatch for drugs/clinical trials and news about 61E3.4 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
ENST00000165086 ENST00000545367 ENST00000542133 ENST00000543660 ENST00000541329
ENST00000539318 ENST00000341400 ENST00000518761 ENST00000543654 ENST00000520808
ENST00000542338 ENST00000539191 ENST00000536041 ENST00000529969 ENST00000540103
ENST00000543449 ENST00000541674 ENST00000544693

miRNA
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Clone
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Primer
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat 61E3.4
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat 61E3.4

2 AceView cDNA sequences:

AW849367 AW849175 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --

See 61E3.4 Protein Expression from SPIRE MOPED and PaxDB    SABiosciences Custom PCR Arrays for 61E3.4
Primer
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat 61E3.4
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for 61E3.4

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

ENSEMBL Gene Tree for 61E3.4 (if available)
TreeFam Gene Tree for 61E3.4 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for 61E3.4 gene
LOC100132247  NPIPL31 2  LOC7288881 2  LOC4403532  ENSG000001980642  LOC7287412  ENSG000002149402  NPIPL12  
PKD1P12  NPIPL22  LOC6427992  LOC1002883322  NPIP2  ENSG000002149672  LOC1005076072  ENSG000002262322  
LOC7299782  LOC6427782  LOC7301532  ENSG000001969932  LOC6130372  
18/19 SIMAP similar genes for 61E3.4 using alignment to 13 protein entries:     E5RHP9_HUMAN (see all proteins) (see all similar genes):
A-575C2.4    NPIPL3    LOC728888    ACSM1    LOC642778    NPIPP1
Nbla00537    LOC728734    ACSM3    NPIP    ACSM2A    ACSM2B
NPIPL1    LOC728741    PKD1P1    LOC339047    NPIPL2    A-589H1.1

61E3.4 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for 61E3.4
PGOHUM00000260907


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/76 NCBI SNPs in 61E3.4 are shown (see all 76    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs2018857941,2
F--21847702(+) TCATCG/CGCTGA 2 /P /R mis11Minor allele frequency- C:0.00EU 505
rs1998680291,2
F--21847708(+) GCTGAT/GGGTGG 2 /H /P mis11Minor allele frequency- G:0.01EU 497
rs2020111551,2
F--21847857(+) TTGATG/ATTATC 2 /N syn11Minor allele frequency- A:0.09EU 304
rs2001377721,2
F--21847910(+) ACGCTC/TGGAAG 2 K E mis11Minor allele frequency- T:0.00EU 587
rs2003279251,2
F--21848336(+) CCCCCG/ACAGAC 2 /R /W mis11Minor allele frequency- A:0.01EU 571
rs285806621,2
C--21848536(-) CGAGCG/ATCAGC 2 /H /R mis11Minor allele frequency- A:0.50NA 2
rs8402761,2
F--21848602(+) CGGCAC/G/TGTGTC 3 H P R mis11NA 4
rs10639141,2
C,F--21848644(-) AGCTCC/TACCCT 2 P L mis13Minor allele frequency- T:0.50NA 6
rs749836991,2
F--21848670(-) TGTCTG/ACTCAC 2 /L syn12Minor allele frequency- A:0.33NA 6
rs763480731,2
F--21848703(-) TCAGCG/AGATGA 2 /A syn13Minor allele frequency- A:0.50NA 8

HapMap Linkage Disequilibrium report for 61E3.4 (21845884 - 21892148 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for 61E3.4: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing 61E3.4
DNA2.0 Custom Variant and Variant Library Synthesis for 61E3.4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for 61E3.4 gene integrated from 9 sources:
(articles sorted by number of sources associating them with 61E3.4)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1 Loftus B.J.... Adams M.D. (1999)
  2. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1 Nagase T....Nomura N. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 440345 AceView: LOC440345.2 Ensembl:ENSG00000185864 euGenes: HUgn440345

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for 61E3.4 gene:
Search GeneIP for patents involving 61E3.4

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section

 
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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VWF
(GIFTS: 73)
von Willebrand factor
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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